ORCID Profile
0000-0002-9148-5685
Current Organisation
University of Adelaide
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Publisher: Springer Science and Business Media LLC
Date: 05-2017
Publisher: Elsevier BV
Date: 10-2020
Publisher: Informa UK Limited
Date: 12-03-2022
Publisher: Informa UK Limited
Date: 08-02-2018
Publisher: Elsevier BV
Date: 03-2018
Publisher: International Digital Organization for Scientific Information (IDOSI)
Date: 02-2017
Publisher: International Digital Organization for Scientific Information (IDOSI)
Date: 12-2016
Publisher: Elsevier BV
Date: 03-2021
Publisher: Elsevier BV
Date: 09-2018
Publisher: Springer Science and Business Media LLC
Date: 11-2017
Publisher: IOP Publishing
Date: 02-06-2017
Publisher: EnPress Publisher
Date: 14-05-2018
Abstract: In this article, generalized differential quadrature method (GDQM) is used to study the free vibrational behavior of variable cross section nano beams. Eringen's nonlocal elastic theory is taken into account to model the small scale effects and nonuniformity is assumed by exponentially varying the width of nano beam. Governing equation of motion is solved using generalized differential quadrature method with different numbers of s ling points. Effects of increasing the s ling points in reaching more accurate results for first three frequency parameters are presented and it is shown that after a specific number of s ling points, results merge to a certain accurate number. It is concluded that generalized differential quadrature method is able to reach the correct answers comparing to analytical results. Moreover, due to the stiffness softening behavior of small-scale structures, necessity of using Eringen's nonlocal elastic theory to model the small scale effects due to the frequency variation is observed.
Publisher: Elsevier BV
Date: 08-2018
Publisher: Springer Science and Business Media LLC
Date: 22-07-2021
Publisher: Oxford University Press (OUP)
Date: 22-09-2017
Abstract: In this paper, dynamic behavior of multi-layered viscoelastic nanobeams resting on a viscoelastic medium with a moving nanoparticle is studied. Eringens nonlocal theory is used to model the small scale effects. Layers are coupled by Kelvin-Voigt viscoelastic medium model. Hamilton's principle, eigen-function technique and the Laplace transform method are employed to solve the governing differential equations. Analytical solutions for transverse displacements of double-layered is presented for both viscoelastic nanobeams embedded in a viscoelastic medium and without it while numerical solution is achieved for higher layered nanobeams. The influences of the nonlocal parameter, stiffness and d ing parameter of medium, internal d ing parameter and number of layers are studied while the nanoparticle passes through. Presented results can be useful in analysing and designing nanocars, nanotruck moving on surfaces, racing nanocars etc.
Publisher: Springer Science and Business Media LLC
Date: 13-11-2020
Publisher: No publisher found
Date: 2022
Publisher: Elsevier BV
Date: 08-2019
Publisher: Elsevier BV
Date: 02-2019
Publisher: Elsevier BV
Date: 06-2017
Publisher: MDPI AG
Date: 17-05-2021
DOI: 10.3390/PH14050478
Abstract: Skeletal myopathy encompasses both atrophy and dysfunction and is a prominent event in cancer and chemotherapy-induced cachexia. Here, we investigate the effects of a chemotherapeutic agent, 5-fluorouracil (5FU), on skeletal muscle mass and function, and whether small-molecule therapeutic candidate, BGP-15, could be protective against the chemotoxic challenge exerted by 5FU. Additionally, we explore the molecular signature of 5FU treatment. Male Balb/c mice received metronomic tri-weekly intraperitoneal delivery of 5FU (23 mg/kg), with and without BGP-15 (15 mg/kg), 6 times in total over a 15 day treatment period. We demonstrated that neither 5FU, nor 5FU combined with BGP-15, affected body composition indices, skeletal muscle mass or function. Adjuvant BGP-15 treatment did, however, prevent the 5FU-induced phosphorylation of p38 MAPK and p65 NF-B subunit, signalling pathways involved in cell stress and inflammatory signalling, respectively. This as associated with mitoprotection. 5FU reduced the expression of the key cytoskeletal proteins, desmin and dystrophin, which was not prevented by BGP-15. Combined, these data show that metronomic delivery of 5FU does not elicit physiological consequences to skeletal muscle mass and function but is implicit in priming skeletal muscle with a molecular signature for myopathy. BGP-15 has modest protective efficacy against the molecular changes induced by 5FU.
Publisher: Springer Science and Business Media LLC
Date: 05-2020
Publisher: Elsevier BV
Date: 08-2019
Publisher: Elsevier BV
Date: 11-2021
Publisher: Springer Science and Business Media LLC
Date: 05-08-2022
DOI: 10.1007/S11071-022-07700-3
Abstract: This paper presents a critical review of the nonlinear dynamics of hyperelastic structures. Hyperelastic structures often undergo large strains when subjected to external time-dependent forces. Hyperelasticity requires specific constitutive laws to describe the mechanical properties of different materials, which are characterised by a nonlinear relationship between stress and strain. Due to recent recognition of the high potential of hyperelastic structures in soft robots and other applications, and the capability of hyperelasticity to model soft biological tissues, the number of studies on hyperelastic structures and materials has grown significantly. Thus, a comprehensive explanation of hyperelastic constitutive laws is presented, and different techniques of continuum mechanics, which are suitable to model these materials, are discussed in this literature review. Furthermore, the sensitivity of each hyperelastic strain energy density function to coefficient variation is shown for some well-known hyperelastic models. Alongside this, the application of hyperelasticity to model the nonlinear dynamics of polymeric structures (e.g., beams, plates, shells, membranes and balloons) is discussed in detail with the assistance of previous studies in this field. The advantages and disadvantages of hyperelastic models are discussed in detail. This present review can stimulate the development of more accurate and reliable models.
Publisher: Elsevier BV
Date: 2023
Publisher: Elsevier BV
Date: 11-2017
Publisher: Springer Science and Business Media LLC
Date: 07-2018
Publisher: International Digital Organization for Scientific Information (IDOSI)
Date: 05-2016
Publisher: Springer Science and Business Media LLC
Date: 31-10-2018
Publisher: Elsevier BV
Date: 03-2022
Publisher: IOP Publishing
Date: 02-05-2018
Publisher: Elsevier BV
Date: 08-2019
Publisher: Elsevier BV
Date: 03-2018
Publisher: Springer Science and Business Media LLC
Date: 20-05-2017
Publisher: Springer Science and Business Media LLC
Date: 09-03-2022
DOI: 10.1007/S00161-022-01090-Y
Abstract: In this study, the time-dependent mechanics of multilayered thick hyperelastic beams are investigated for the first time using five different types of shear deformation models for modelling the beam (i.e. the Euler–Bernoulli, Timoshenko, third-order, trigonometric and exponential shear deformable models), together with the von Kármán geometrical nonlinearity and Mooney–Rivlin hyperelastic strain energy density. The laminated hyperelastic beam is assumed to be resting on a nonlinear foundation and undergoing a time-dependent external force. The coupled highly nonlinear hyperelastic equations of motion are obtained by considering the longitudinal, transverse and rotation motions and are solved using a dynamic equilibrium technique. Both the linear and nonlinear time-dependent mechanics of the structure are analysed for cl ed–cl ed and pinned–pinned boundaries, and the impact of considering the shear effect using different shear deformation theories is discussed in detail. The influence of layering, each layer’s thickness, hyperelastic material positioning and many other parameters on the nonlinear frequency response is analysed, and it is shown that the resonance position, maximum litude, coupled motion and natural frequencies vary significantly for various hyperelastic and layer properties. The results of this study should be useful when studying layered soft structures, such as multilayer plastic packaging and laminated tubes, as well as modelling layered soft tissues.
Publisher: Elsevier BV
Date: 05-2018
No related grants have been discovered for Hossein Bakhshi Khaniki.