ORCID Profile
0000-0001-7704-9441
Current Organisations
University of Helsinki, Clinicum
,
Helsinki University Central Hospital
,
University of Helsinki
,
Helsingin Yliopisto Laaketieteellinen tiedekunta
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Publications
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Publisher: Elsevier BV
Date: 12-2019
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa
Publisher: American Psychiatric Association Publishing
Date: 09-2017
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Publisher: Springer Science and Business Media LLC
Date: 15-07-2019
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
Publisher: Springer Science and Business Media LLC
Date: 27-04-2020
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Publisher: Elsevier BV
Date: 10-2022
Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches
Publisher: Elsevier BV
Date: 10-2019
Analysis of shared heritability in common disorders of the brain
Publisher: American Association for the Advancement of Science (AAAS)
Date: 22-06-2018
Abstract: Consistent classification of neuropsychiatric diseases is problematic because it can lead to misunderstanding of etiology. The Brainstorm Consortium examined multiple genome-wide association studies drawn from more than 200,000 patients for 25 brain-associated disorders and 17 phenotypes. Broadly, it appears that psychiatric and neurologic disorders share relatively little common genetic risk. However, different and independent pathways can result in similar clinical manifestations (e.g., psychosis, which occurs in both schizophrenia and Alzheimer's disease). Schizophrenia correlated with many psychiatric disorders, whereas the immunopathological affliction Crohn's disease did not, and posttraumatic stress syndrome was also largely independent of underlying traits. Essentially, the earlier the onset of a disorder, the more inheritable it appeared to be. Science , this issue p. eaap8757
Shared genetic risk between eating disorder‐ and substance‐use‐related phenotypes: Evidence from genome‐wide association studies
Publisher: Wiley
Date: 16-02-2020
DOI: 10.1111/ADB.12880
Genome‐wide association analysis of eating disorder‐related symptoms, behaviors, and personality traits
Publisher: Wiley
Date: 22-08-2012
DOI: 10.1002/AJMG.B.32087
Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa
Publisher: Springer Science and Business Media LLC
Date: 25-07-2017
DOI: 10.1038/MP.2017.88
Abstract: Anorexia nervosa (AN) is a complex neuropsychiatric disorder presenting with dangerously low body weight, and a deep and persistent fear of gaining weight. To date, only one genome-wide significant locus associated with AN has been identified. We performed an exome-chip based genome-wide association studies (GWAS) in 2158 cases from nine populations of European origin and 15 485 ancestrally matched controls. Unlike previous studies, this GWAS also probed association in low-frequency and rare variants. Sixteen independent variants were taken forward for in silico and de novo replication (11 common and 5 rare). No findings reached genome-wide significance. Two notable common variants were identified: rs10791286, an intronic variant in OPCML ( P =9.89 × 10 −6 ), and rs7700147, an intergenic variant ( P =2.93 × 10 −5 ). No low-frequency variant associations were identified at genome-wide significance, although the study was well-powered to detect low-frequency variants with large effect sizes, suggesting that there may be no AN loci in this genomic search space with large effect sizes.
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Publisher: Elsevier BV
Date: 02-2022
Related Organisations
Related Funding Activities
No related grants have been discovered for Anu Raevuori.