ORCID Profile
0000-0002-8272-9641
Current Organisations
Chris O’Brien Lifehouse
,
Port Macquarie Base Hospital
,
Port Macquarie Private Hospital
,
The Christie NHS foundation trust
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Publications
Impact of COVID ‐19, gender, race, specialty and seniority on mental health during surgical training: an international study
Publisher: Wiley
Date: 18-08-2022
DOI: 10.1111/ANS.17980
Abstract: Superior patient outcomes rely on surgical training being optimized. Accordingly, we conducted an international, prospective, cross‐sectional study determining relative impacts of COVID‐19, gender, race, specialty and seniority on mental health of surgical trainees. Trainees across Australia, New Zealand and UK enrolled in surgical training accredited by the Royal Australasian College of Surgeons or Royal College of Surgeons were included. Outcomes included the short version of the Perceived Stress Scale, Oxford Happiness Questionnaire short scale, Patient Health Questionnaire‐2 and the effect on in idual stress levels of training experiences affected by COVID‐19. Predictors included trainee characteristics and local COVID‐19 prevalence. Multivariable linear regression analyses were conducted to assess association between outcomes and predictors. Two hundred and five surgical trainees were included. Increased stress was associated with number of COVID‐19 patients treated ( P = 0.0127), female gender ( P = 0.0293), minority race ( P = 0.0012), less seniority ( P = 0.001), and greater COVID‐19 prevalence ( P = 0.0122). Lower happiness was associated with training country ( P = 0.0026), minority race ( P = 0.0258) and more seniority ( P 0.0001). Greater depression was associated with more seniority ( P 0.0001). Greater COVID‐19 prevalence was associated with greater reported loss of training opportunities ( P = 0.0038), poor working conditions ( P = 0.0079), personal protective equipment availability ( P = 0.0008), relocation to areas of little experience ( P 0.0001), difficulties with career progression ( P = 0.0172), loss of supervision ( P = 0.0211), difficulties with pay ( P = 0.0034), and difficulties with leave ( P = 0.0002). This is the first study to specifically describe the relative impacts of COVID‐19 community prevalence, gender, race, surgical specialty and level of seniority on stress, happiness and depression of surgical trainees on an international scale.
The clinical academic workforce in Australia and New Zealand: report on the second binational summit to implement a sustainable training pathway
Publisher: Wiley
Date: 05-0005
DOI: 10.1111/IMJ.13356
Abstract: There has been a decline in the proportion of clinical academics compared with full-time clinicians, since 2004. A Working Party was established to help develop and implement a model for the training of clinical academics. After a highly successful first summit in 2014 that summarised the challenges faced by clinical academics in Australia and New Zealand, a second summit was convened late in 2015 to report on progress and to identify key areas for further action. The second summit provided survey results that identified the varied training pathways currently offered to clinical academics and the institutions willing to be involved in developing improved pathways. A literature review also described the contributions that clinical academics make to the health sector and the challenges faced by this workforce sector. Current training pathways created for clinical academics by Australasian institutions were presented as ex les of what can be done. The perspectives of government and research organisations presented at the summit helped define how key stakeholders can contribute. Following the summit, there was a strong commitment to continue to work towards developing a sustainable and defined training pathway for clinical academics. The need for a coordinated and integrated approach was highlighted. Some key objectives were agreed upon for the next phase, including identifying and engaging key advocates within government and leading institutions publishing and profiling the contributions of successful clinical academics to healthcare outcomes defining the stages of a clinical academic training pathway and establishing a mentoring programme for training clinical academics.
Building a sustainable clinical academic workforce to meet the future healthcare needs of A ustralia and N ew Z ealand: report from the first summit meeting
Publisher: Wiley
Date: 09-2015
DOI: 10.1111/IMJ.12854
Abstract: The delivery of healthcare that meets the requirements for quality, safety and cost-effectiveness relies on a well-trained medical workforce, including clinical academics whose career includes a specific commitment to research, education and/or leadership. In 2011, the Medical Deans of Australia and New Zealand published a review on the clinical academic workforce and recommended the development of an integrated training pathway for clinical academics. A bi-national Summit on Clinical Academic Training was recently convened to bring together all relevant stakeholders to determine how best to do this. An important part understood the lessons learnt from the UK experience after 10 years since the introduction of an integrated training pathway. The outcome of the summit was to endorse strongly the recommendations of the medical deans. A steering committee has been established to identify further stakeholders, solicit more information from stakeholder organisations, convene a follow-up summit meeting in late 2015, recruit pilot host institutions and engage the government and future funders.
Achieving safe surgery after COVID‐19 vaccination
Publisher: Wiley
Date: 05-2022
DOI: 10.1111/ANS.17654
Reply to letter to the editor
Publisher: Elsevier BV
Date: 2013
Progress towards a sustainable clinical academic training pathway
Publisher: Wiley
Date: 10-2018
DOI: 10.1111/ANS.14706
Outcomes following radical inguinal lymphadenectomy for penile cancer using a fascial-sparing surgical technique
Publisher: Springer Science and Business Media LLC
Date: 05-04-2023
Comparing pre-operative and intra-operative bacteriuria during ureteroscopy with laser lithotripsy: A prospective cohort study
Publisher: Elsevier BV
Date: 03-2019
The AMA Specialist Trainee Survey 2014: a survey of hospital-based specialty trainees and general practice registrars
Publisher: AMPCo
Date: 09-2015
DOI: 10.5694/MJA15.00396
Fostering creativity and innovation in the health system: The role of doctors-in-training in biomedical innovation and entrepreneurship
Publisher: AMPCo
Date: 07-2015
DOI: 10.5694/MJA14.01185
Gubernaculum as icebreaker: Do matrix metalloproteinases in rodent gubernaculum and inguinal fat pad permit testicular descent?
Publisher: Elsevier BV
Date: 12-2011
DOI: 10.1016/J.JPEDSURG.2011.09.025
Abstract: Cryptorchidism is the most common male congenital abnormality. The rodent gubernaculum steers the testis from abdomen to scrotum postnatally by eversion and migration through the developing inguinal fat pad (IFP). We hypothesize that extracellular matrix remodeling in/around the gubernaculum is necessary for eversion and migration and is permitted by timed IFP maturation and aimed to examine regional development and matrix metalloproteinase (MMP) content. Embryonic day 19 (E19) and postnatal days 0 and 2 (P0, P2) wild-type Sprague-Dawley rats (n = 10) were prepared for histologic examination (trichrome) and immunohistochemistry (membrane-type MMP-1 [MT1-MMP], MMP2) and analyzed using light/confocal microscopy. At E19, IFP contained fibroblasts and immature cells in an extensive collagenous extracellular matrix. Cells in the gubernaculum base were cytoplasmic-MT1-MMP-positive (inactive). At P0, the gubernaculum had everted, and adjacent cells were membranous-MT1-MMP-positive (active). At P2, the gubernaculum was migrating through the IFP, and adjacent cells were membranous-MT1-MMP-positive. Adipocyte maturation began cranially in the IFP and proceeded in a craniocaudal gradient until more uniformly mature at P2. The MT1-MMP-positive cells may remodel the gubernaculum for eversion and provide the collagenolysis necessary for migration, like an icebreaking ship, through the IFP, which matures to permit migration through collagen-rich tissue. Disruption of these processes may cause cryptorchidism.
Improving clinical teaching for busy clinicians: integration of the one-minute preceptor into mini-clinical examination
Publisher: Wiley
Date: 07-2017
DOI: 10.1111/ANS.14038
Challenges and next steps in teaching professionalism in surgical training
Publisher: Wiley
Date: 06-2017
DOI: 10.1111/ANS.14016
Is matrix metalloproteinase required in postnatal testicular tubules for germ cell maturation?
Publisher: Elsevier BV
Date: 07-2012
DOI: 10.1016/J.JPEDSURG.2012.03.062
Abstract: Cryptorchidism may cause infertility by failed transformation of neonatal gonocytes into adult dark spermatogonia, the putative stem cells for spermatogenesis. Gonocytes migrate centrifugally to the tubular basement membrane to become adult dark spermatogonia. Regulation of this transformation remains unknown. We aimed to investigate neonatal rodent testis matrix metalloproteinase (MMP) production to see whether MMPs loosen extracellular matrix between Sertoli cells to facilitate gonocyte movement. Sprague-Dawley rat testes (n = 4-6 per group) were collected at embryonic day 19 (E19) and postnatal (P) days P0 to 10 for immunohistochemistry. Immunofluorescent confocal images were captured for presence of membrane type 1 MMP (MT1-MMP), matrix metalloproteinase 2 (MMP2), tissue inhibitor of metalloproteinase 2 (TIMP2), mouse VASA homologue, anti-Müllerian hormone, and androgen receptor in tissue sections. Testicular proteins were analyzed by immunoblotting. Membrane type 1 MMP was strongly present in gonocytes at E19 then decreased, whereas it increased in testicular somatic cells from P0 to P10. Testicular protein levels of MT1-MMP, MMP2, and androgen receptor were constant from E19 to P10. Anti-Müllerian hormone protein sharply decreased after P2, whereas TIMP2 gradually increased from E19 to P10. Gonocytes migrated to basement membrane at P2 to P6. Membrane type 1 MMP, MMP2, and TIMP2 were present in testis from E19 to P10 during gonocyte migration and transformation into spermatogenic stem cells. Increased knowledge about germ cell development may aid efforts to improve fertility in cryptorchidism.
Related Organisations
The Christie NHS Foundation Trust
Location: United Kingdom of Great Britain and Northern Ireland
Related Funding Activities
No related grants have been discovered for James Anthony Churchill.