ORCID Profile
0000-0003-2836-6429
Current Organisation
University of California, San Diego
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Publisher: Frontiers Media SA
Date: 16-04-2014
Publisher: Springer Singapore
Date: 2018
Publisher: Springer Singapore
Date: 2018
Publisher: Frontiers Media SA
Date: 17-06-2015
Publisher: Springer Singapore
Date: 2018
Publisher: Public Library of Science (PLoS)
Date: 04-06-2015
Publisher: Frontiers Media SA
Date: 2014
Publisher: Springer Singapore
Date: 2018
Publisher: Elsevier BV
Date: 10-2018
DOI: 10.1016/J.PHYSBEH.2018.06.032
Abstract: In neuroscience literature, dopamine is often considered as a pleasure chemical of the brain. Dopaminergic neurons respond to rewarding stimuli which include primary rewards like opioids or food, or more abstract forms of reward like cash rewards or pictures of pretty faces. It is this reward-related aspect of dopamine, particularly its association with reward prediction error, that is highlighted by a large class of computational models of dopamine signaling. Dopamine is also a neuromodulator, controlling synaptic plasticity in several cortical and subcortical areas. But dopamine's influence is not limited to the nervous system its effects are also found in other physiological systems, particularly the circulatory system. Importantly, dopamine agonists have been used as a drug to control blood pressure. Is there a theoretical, conceptual connection that reconciles dopamine's effects in the nervous system with those in the circulatory system? This perspective article integrates the erse physiological roles of dopamine and provides a simple theoretical framework arguing that its reward related function regulates the processes of energy consumption and acquisition in the body. We conclude by suggesting that energy-related book-keeping of the body at the physiological level is the common motif that links the many facets of dopamine and its functions.
Publisher: Frontiers Media SA
Date: 09-01-2017
Location: United States of America
No related grants have been discovered for pragathi priyadharsini balasubramani.