ORCID Profile
0000-0002-4893-6583
Current Organisation
University of Nottingham
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Publisher: Public Library of Science (PLoS)
Date: 03-01-2012
Publisher: Springer Science and Business Media LLC
Date: 2012
Publisher: Springer Science and Business Media LLC
Date: 10-2015
Publisher: Springer Science and Business Media LLC
Date: 2013
Publisher: BMJ
Date: 12-2016
Publisher: Springer Science and Business Media LLC
Date: 2013
Publisher: Wiley
Date: 2018
DOI: 10.1136/VR.104390
Abstract: There is little peer-reviewed research assessing therapeutic effectiveness in canine eye disease. Current treatments used in first opinion and ophthalmology referral practices are also somewhat poorly documented. The aim of this study was to investigate the current management of canine keratoconjunctivitis sicca (KCS) and acute primary angle-closure glaucoma (PACG) by veterinary surgeons. Questionnaires using clinical vignettes were administered to a cross section of general practitioners ('GPs') and veterinarians engaged in or training for postgraduate ophthalmology practice ('PGs'). Similar treatment recommendations for KCS (topical cyclosporine, lubricant, antibiotic) were given by both groups of veterinarians with the single exception of increased topical antibiotic use by GPs. Treatment of acute glaucoma erged between groups: PGs were much more likely to recommend topical prostaglandin analogues and a wider array of both topical and systemic treatments were recommended by both groups. Systemic ocular hypotensive agents were suggested infrequently. Our results suggest that treatments may vary substantially in ocular conditions, particularly in conditions for which neither guidelines nor high-quality evidence exists. This study highlights the need for novel strategies to address evidence gaps in veterinary medicine, as well as for better evaluation and dissemination of current treatment experience.
Publisher: Elsevier BV
Date: 05-2008
DOI: 10.1016/J.PREVETMED.2007.12.009
Abstract: Little is known regarding the types and frequencies of contact that exist between farms and which of these may act as pathogen transmission routes however it is likely that farms demonstrate considerable heterogeneity in such contacts. In this cross-sectional study, we explored the direct and indirect contact types and frequencies that exist between cattle farms within a region, focusing on potential routes of pathogen transmission. The owners/managers of 56 farms located in a 10 km by 10 km study area in north-west England were administered an interview-based questionnaire between June and September 2005. Information was obtained relating to contact types and frequencies, including those involving animal movements, equipment sharing between farms and any contractors or companies visiting the farms. The data was explored using hierarchical cluster analysis and network analysis. There was considerable variation between farms arising from different contact types. Some networks exhibited great connectivity, incorporating approximately 90% of the farms interviewed in a single component, whilst other networks were more fragmented, with multiple small components (sets of connected farms not linked with other farms). A range of factors influencing contact between farms were identified. For ex le, contiguous farms were more likely to be linked via other contacts, such as sharing of equipment and direct farm-to-farm animal movements (p<0.001 and p=0.02, respectively). The frequency of contacts was also investigated it is likely that the amount of contact a farm receives from a company or contractor and whether or not biosecurity is performed after contact would impact on disease transmission potential. We found considerable heterogeneity in contact frequency and that many company and contractor personnel undertook little biosecurity. These findings lead to greater understanding of inter-farm contact and may aid development of appropriate biosecurity practices and control procedures, and inform mathematical modelling of infectious diseases.
Publisher: Informa UK Limited
Date: 03-07-2017
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Marnie Brennan.