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0000-0003-3444-8519
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Universidade Estadual Paulista Júlio de Mesquita Filho
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Publisher: Springer Science and Business Media LLC
Date: 24-07-2015
DOI: 10.1007/S00784-015-1534-0
Abstract: The aim of this study was to evaluate the influence of systemic administration of antibiotics (amoxicillin and tetracycline) at the different phases of the repair process (7, 15, 30 days) in immediate rat tooth replantation. Ninety rats had their incisors extracted and stored in saline for 5 min. Next, the teeth were replanted, and the animals were assigned to three groups according to the antibiotic administered by oral gavage: control group, amoxycillin group, and tetracycline group. Euthanasia was performed at 7, 15, and 30 days after replantation. Regardless of the evaluation period, the connective tissue underlying the epithelial attachment and the periodontal ligament showed statistically significant difference relative to the acute inflammatory infiltrate, which was more intense in the control group followed by the tetracycline group. These results point to the fact that systemic antibiotic therapy (SAT) in immediate tooth replantation is beneficial to pulpal and periodontal ligament repair and that amoxycillin is an excellent option. There is a lack of randomized studies assessing how the use of systemic antibiotics could influence tooth healing after immediate replantation.
Publisher: No publisher found
Date: 2017
Publisher: Elsevier BV
Date: 06-2021
Publisher: Revista Ciencias em Saude
Date: 14-05-2020
DOI: 10.21876/RCSHCI.V10I2.930
Abstract: Objective: To identify the presence and level of halitosis in edentulous in iduals with or without prostheses, before and after rehabilitation with complete dentures (CD). Methods: Patients were verbally invited to participate and signed an Informed Consent. Halitosis was analyzed by the volatile sulfur compounds measurement method in the presence and absence of the old prostheses (M1) and 15 to 30 days after the patients received their new prostheses (M2). At M1, the patients answered a questionnaire with clinical data, and the saliva type and presence/absence of tongue coating were assessed. T-test and Spearman correlation test were used, and a p-value 0,05 was considered statistically significant. Results: Twenty-seven patients (19 women) with an average age of 67 years participated in the study. The mean time of prosthesis usage was 20.2 years. Tong coating was present in 21 patients (77,8%). A good odor level of halitosis was self-claimed in 13 (41,8%) in iduals. The odor level of halitosis was significantly lower in M2 compared to M1, either with or without CD and after hygiene (p 0,001). There was a positive and statistically significant correlation between the level of halitosis and alcoholism, smoking, prostheses hygiene method, and the presence of disease (diabetes). Conclusion: The old complete replacement of the prostheses with new ones was able to improve the odor level in a period of 15 to 30 days after the treatment. The presence of halitosis was correlated with alcoholism, smoking, denture hygiene methods, and the presence of diabetes.
Publisher: Research, Society and Development
Date: 21-07-2020
Abstract: The act of caring, being responsible for the survival and quality of life of others, represent extra activities that can cause socio-emotional changes to those who perform this function. Objective: To assess the quality of life, depression, anxiety and stress of caregivers of people with or without Down syndrome. Methodology: 144 caregivers were ided into Control Group (caregivers of typical children) and Down Syndrome Group (caregivers of people with Down Syndrome). The controlled observational cross-sectional study was prepared in accordance with the Declaration of Helsinki and approved by the Human Ethics Committee. To achieve the objectives, validated questionnaires related to the theme were applied. The data were subjected to the Chi-square test with modified Bonferroni post hoc and Rank or Pearson correlation tests. Results: The Down Syndrome Group had a lower quality of life related to the psychological domain and a higher environmental domain than the Control Group. In the groups studied, quality of life and family income showed a positive correlation (p = 0.02) and there was no difference in depression. The Control Group had a higher rate of anxiety and the Down Syndrome Group had a higher rate of physical symptoms of stress correlated with the degree of dependence of the Down Syndrome patient (p = 0.04). Conclusion: Family income is an important factor for a better quality of life, symptoms of physical stress reduce the quality of life in the psychological domain and symptoms of physical stress of caregivers are correlated with a greater degree of dependence of patients with Down Syndrome.
Publisher: Elsevier BV
Date: 07-2016
DOI: 10.1016/J.ARCHORALBIO.2016.03.008
Abstract: To compare electrical activity in the anterior temporal and masseter muscles on the habitual (HMS) and non-habitual mastication side (NHMS), during mastication and in the mandibular postural position. In addition, the increase in electrical activity during mastication was assessed for the HMS and NHMS, analysing both working (WSM) and non-working side during mastication (NWSM). A total of 28 healthy women (18-32 years) participated in the study. They were submitted to Kazazoglu's test to identify the HMS. Bioresearch 'Bio EMG' software and bipolar surface electrodes were used in the exams. The exams were conducted in the postural position and during the unilateral mastication of raisins, on both the HMS and NHMS. The working and non-working side on HMS and NHMS were assessed separately. The obtained data were then statistically analysed with SPSS 20.0, using the Paired S les Test at a significance level of 95%. The differences in the average EMG values between HMS and NHMS were not statistically significant in the postural position (Temporal p=0.2 Masseter p=0.4) or during mastication (Temporal WSM p=0.8 Temporal NWSM p=0.8 Masseter WSM p=0.6 Masseter NWSM p=0.2). Differences in the increase in electrical activity between the masseter and temporal muscles occurred on the working side, on the HMS and NHMS (p=0.0), but not on the non-working side: HMS (p=0.9) and NHMS (p=0.3). The increase in electrical activity was about 35% higher in the masseter than in the temporal muscle. Mastication side preference does not significantly impact electrical activity of the anterior temporal and masseter muscles during mastication or in postural position.
Publisher: Research, Society and Development
Date: 06-07-2020
Abstract: As fraturas faciais têm incidência variável de acordo com idade e gênero do in íduo, localização geográfica e aspectos culturais, posição socioeconômica, influência do clima e tempo, utilização de álcool e drogas, variação das legislações de trânsito, violência doméstica e fatores etiológicos. Com o objetivo de verificar a epidemiologia do trauma facial na região de Araçatuba – SP, foi realizado um levantamento retrospectivo de vinte anos a partir dos prontuários de pacientes atendidos no Serviço de Cirurgia e Traumatologia Bucomaxilofacial da Unesp Araçatuba, verificando a incidência, fatores etiológicos, faixa etária e gênero de pacientes que sofreram múltiplas fraturas de face. Os dados obtidos foram inseridos no EpiInfo, para a realização da contagem e estatística (Teste de correlação de Spearman). Foram avaliados 2770 prontuários, dos quais, 357 pacientes apresentaram mais de uma fratura na face. Foi observado que houve uma maior prevalência em pacientes do gênero masculino (p .05). O fator etiológico em destaque foi o acidente motociclístico seguido dos acidentes automobilísticos e a agressão física. Múltiplas fraturas em face são eventos muito frequentes nas emergências hospitalares, sendo que os homens são mais frequentemente atingidos, e os acidentes de alto impacto os que mais determinam a gravidade e a associação de fraturas faciais.
Publisher: Medknow
Date: 2016
Abstract: A better understanding of the relation between traumatic dental occlusion and periodontal changes is needed. This study aimed to evaluate the pattern of osteoclastic activity in the periodontal bone in front of the traumatic dental occlusion in rat molars. Traumatic dental occlusion (TO) was induced in twenty rats, which were sacrificed after periods of 2, 5, 7, and 14 days. Transversal histological sections of both jaws were stained with tartrate-resistant acid phosphatase and hematoxylin and eosin. Mann-Whitney U-test was used for group comparison, and Pearson's correlation test was applied for the number of osteoclasts and bone area (BA). Traumatic dental occlusion caused an increase in the number of osteoclasts in the bone of the upper and lower right first molar from days 2-5 to 2-14, respectively. In the TO groups, the number of osteoclasts on the lamina dura and in the center of the alveolar bone septum, respectively, increased almost 4-fold and 9-fold in the lower jaw and 3-fold and 5-fold in the upper jaw, during all periods. In the TO groups, the BA of the alveolar bone septum was substantially reduced. There was a negative correlation between the number of osteoclasts and BA in both jaws during all experimental periods. Traumatic dental occlusion increases osteoclast activity in the alveolar lamina dura and in the center of alveolar bone and stimulates a higher degradation in the center of the alveolar bone septum.
Publisher: Wiley
Date: 19-08-2011
DOI: 10.1111/J.1600-9657.2011.01023.X
Abstract: The prognosis of tooth replantation is usually related to the need of endodontic treatment, which has a direct relationship with the occurrence of root resorptions. Several studies have been undertaken in an attempt to prevent, delay, or treat these complications, which are the main causes of loss of replanted teeth. This literature review examines research evidence on intracanal dressings and root canal filling materials used in cases of tooth replantation. A comprehensive search was performed in the Medline/Pubmed, Bireme and Scielo full-text electronic journal databases to retrieve English-language articles referring to these topics that had been published between 1964 and 2010. Calcium hydroxide (CH) remains the usually recommended choice as an intracanal medicament in replanted teeth however, there is evidence to support the initial use of a corticosteroid-antibiotic combination such as Ledermix paste to control potential early resorption, prior to the introduction of CH where the beneficial effect in the treatment of progressive root resorption has been well proven. Regarding root filling materials, CH-containing sealers are a good option because of their biological properties. Accurate diagnosis and adequate treatment plan may constitute very complex tasks, particularly in tooth avulsion because several variables are involved. In addition to the technical knowledge and clinical experience directed toward the quality of treatment, patient education may favorably influence the survival of replanted teeth.
Publisher: Elsevier BV
Date: 07-2016
DOI: 10.1016/J.PROSDENT.2015.12.014
Abstract: Dentists often note problems with infection in patients with maxillofacial prostheses. Conventional disinfection protocols are not always effective and may alter the properties of the polymer used in the prosthesis. Thus, the search for improved disinfection methods is important. The purpose of this in vitro study was to evaluate and compare the antimicrobial activity of conventional disinfectant solutions (water and neutral soap and 4% chlorhexidine) and plant extracts (Cymbopogon nardus and Hydrastis canadensis) on specimens of maxillofacial silicone contaminated with Candida albicans and Staphylococcus aureus biofilms. Seventy-two silicone (MDX4-4210) specimens were fabricated (5×2 mm) and sterilized. Thirty-six were contaminated with C albicans (10(6) cells/mL) and 36 with S aureus (10(8) cells/mL) to evaluate the antimicrobial activity of the cleaning protocols. After incubation (37°C/72 hours), the specimens were ided into 5 groups: not disinfected (positive control), soaking in saline solution for 10 minutes, soaking in 4% chlorhexidine for 10 minutes, soaking in C nardus for 10 minutes, soaking in H canadensis for 10 minutes, and washing by hand with water and neutral soap for 30 seconds. The viability of cells was evaluated by XTT (2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide) assay and by scanning electron microscope analysis. The results were analyzed by ANOVA and the Tukey HSD test (α=.05). All disinfection solutions provided a statistically significant reduction in biofilm viability compared with the control group for both microorganisms (P<.05). Washing with water and neutral soap was significantly more effective in reducing biofilm viability than immersion in the disinfection solutions, with persistence of viable microorganisms between 1.05% for C albicans and 0.62% for S aureus after this cleaning protocol. Photomicrographs revealed that 4% chlorhexidine altered the surface of the polymer. Within the limitations of this in vitro study, it was concluded that the cleaning protocols with different disinfectant solutions produced a significant reduction in the viability of C albicans and S aureus biofilms on the silicone polymer. Washing with water and neutral soap was the most effective protocol against both microorganisms.
Publisher: American Diabetes Association
Date: 18-01-2019
DOI: 10.2337/DC18-2248
Abstract: Given the role of gut microbiota in regulating metabolism, probiotics administered during pregnancy might prevent gestational diabetes mellitus (GDM). This question has not previously been studied in high-risk overweight and obese pregnant women. We aimed to determine whether probiotics (Lactobacillus rhamnosus and Bifidobacterium animalis subspecies lactis) administered from the second trimester in overweight and obese women prevent GDM as assessed by an oral glucose tolerance test (OGTT) at 28 weeks’ gestation. Secondary outcomes included maternal and neonatal complications, maternal blood pressure and BMI, and infant body composition. This was a double-blind randomized controlled trial of probiotic versus placebo in overweight and obese pregnant women in Brisbane, Australia. The study was completed in 411 women. GDM occurred in 12.3% (25 of 204) in the placebo arm and 18.4% (38 of 207) in the probiotics arm (P = 0.10). At OGTT, mean fasting glucose was higher in women randomized to probiotics (79.3 mg/dL) compared with placebo (77.5 mg/dL) (P = 0.049). One- and two-hour glucose measures were similar. Preecl sia occurred in 9.2% of women randomized to probiotics compared with 4.9% in the placebo arm (P = 0.09). Excessive weight gain occurred in 32.5% of women in the probiotics arm (55 of 169) compared with 46% in the placebo arm (81 of 176) (P = 0.01). Rates of small for gestational age (& th percentile) were 2.4% in the probiotics arm (5 of 205) and 6.5% in the placebo arm (13 of 199) (P = 0.042). There were no differences in other secondary outcomes. The probiotics used in this study did not prevent GDM in overweight and obese pregnant women.
Publisher: Wiley
Date: 17-05-2018
DOI: 10.1111/EDT.12402
Abstract: The storage media is directly related to the prognosis of avulsed teeth, with resveratrol drawing attention due to its antioxidant and anti-inflammatory proprieties. The aim of this study was to evaluate the repair process in rat teeth following delayed replantation after storage in resveratrol (R) dissolved in dimethyl sulphoxide (DMSO). The upper right central incisors of 36 rats were ided into 4 groups. In group I, the teeth were extracted and immediately replanted. Group II teeth were stored in 50 mL R+DMSO (0.0512 g/mL), whereas group III teeth were stored in 50 mL pure DMSO, both for a period of 60 minutes. The teeth of group IV were stored dry for 60 minutes. The teeth of groups II, III and IV were then replanted, and the animals were euthanized after 60 days. Longitudinal histological cuts were HE stained for histomorphometric analysis of the periodontal ligament, alveolar bone, cementum and dentin. The analysis of HE stained histological sections showed the following statistical differences: the acute inflammatory process in the epithelial insertion was less prominent in group II than in group III the organization of the periodontal ligament was better in group I, while the intensity and extension of acute inflammation in the periodontal ligament were better in group I, and worse in group III the chronic inflammatory infiltrate was less in groups I and IV, and the depth and extent of resorption, as well as the repair of root resorption, were better in group I. Storage in R+DMSO solution did not inhibit root resorption after delayed replantation in rat teeth. It is concluded that pure DMSO is not a suitable transport medium for avulsed teeth.
Publisher: Wiley
Date: 24-09-2020
DOI: 10.1111/EDT.12601
Publisher: Editora Cubo
Date: 23-03-2017
DOI: 10.14295/BDS.2017.V20I1.1307
Abstract: Dental avulsion is the most severe type of dentoalveolar trauma, and the treatment of choice for this type of injury should be the replantation of the exarticulated tooth. After conducting a review of the literature and holding discussions with experienced researchers and clinical specialists from different areas, the International Association of Dental Traumatology (IADT) proposed a protocol for tooth replantation, including a recommendation for systemic antibiotic therapy (SAT) to reduce the risk of root resorption. Several antibiotics have been tested, but tetracycline and amoxicillin are, by far, the most commonly used drugs for avulsion injuries. This paper reviews the literature on the prescription of SAT in cases of immediate and delayed replantation of accidentally avulsed permanent teeth, based on a critical analysis of full-length papers retrieved from the PubMed/Medline, Bireme and SciELO electronic databases. Original research reports and literature reviews published in English-language journals between 1966 and 2016, and directly or indirectly discussing the relation between antibiotic therapy and the replantation of permanent teeth, were searched using “tooth avulsion,” “systemic antibiotic therapy” and “tooth replantation” as key words. The prescription of antibiotics for tooth replantation was found to be a controversial subject, and randomized clinical studies are needed to determine whether antibiotics for tooth replantation are actual indicated. Until the results of these studies become available, the recommendation is to use SAT for the management of permanent teeth replanted after an accidental avulsion. The best prescription option is tetracycline for 7 days, and the second best prescription option is amoxicillin for 4 to 7 days.
Publisher: Research, Society and Development
Date: 14-09-2020
Abstract: O objetivo do estudo foi avaliar o processo de reparo periodontal de dentes de ratos reimplantados conservados em solução de α e β-amirina a 10%. Foram utilizados incisivos superiores direitos de 36 ratos ididos em 3 grupos, os dentes foram extraídos e deixados em meio seco e no respectivo meio de conservação por 20 minutos e reimplantados. A isão dos grupos foi de acordo com o meio de conservação utilizado: SO – soro fisiológico 0,9% AMSC - solução de α e β-amirina a 10%, sem tratamento endodôntico e AMCC - solução de α e β-amirina a 10%, com tratamento endodôntico. Após 60 dias foi realizada eutanásia por perfusão transcardíaca. Os cortes obtidos foram corados em Hematoxilina e Eosina e Picrosirius Red. Foi avaliada matriz extracelular e vasos sanguíneos, perfil nuclear, fibras colágenas, organização do ligamento periodontal, extensão e intensidade do processo inflamatório, reabsorção dentária e anquilose. O teste de Kruskal-Wallis foi utilizado para comparação entre grupos. Dentre as diferenças significativas, o terço apical da raiz no grupo AMCC obteve maior área de vasos sanguíneos em comparação a SO, menor área de fibras colágenas de birrefringência vermelha e maior de fibras verdes, ao contrário, AMSC apresentou maior área de fibras de birrefringência vermelha e menor de fibras verdes. As outras variáveis não apresentaram diferença entre os grupos. Conclui-se que a mistura de α e β-amirina em ambiente pré-clínico mostrou possuir potencial para utilização como meio de conservação em avulsão dentária.
Publisher: Medical Association of Pharmacopuncture Institute
Date: 04-2017
DOI: 10.1016/J.JAMS.2017.01.004
Abstract: Paresthesia is defined as an alteration in local sensibility, associated with numbness, tingling, or unpleasant sensations caused by nerve lesions or irritation. It can be temporary or permanent. The treatment protocol for facial paresthesia is primarily based on the use of drugs and implant removal, which may not be completely effective or may require other risk exposure when there is no spontaneous regression. However, other therapeutic modalities such as acupuncture can be used. The aim of this study is to report a case of a patient with paresthesia of the inferior alveolar nerve and pain caused by an implant surgery performed 2 years earlier. The patient received acupuncture treatment during 4 months of weekly sessions. Six points were used: Large Intestine (LI4), Large Intestine (LI11), Stomach (ST36), Liver (LR3), Extra Head and Neck (E-HN-18), and Stomach (ST5). The visual analog scale was used before and after each session for the analysis of paresthesia and pain, together with assessment of the paresthesia by delimitation of the desensitized region of the skin and presented discomfort. Pain remission and reduction in the size of the paresthesia area occurred after four sessions.
Publisher: Operative Dentistry
Date: 11-2011
DOI: 10.2341/10-152-S
Abstract: Knowledge of the characteristics and etiologies of noncarious cervical lesions assists dentists in selecting an appropriate treatment and improving the prognosis.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 11-2011
Publisher: SAGE Publications
Date: 25-02-2021
Abstract: Tooth avulsion is a common cause of tooth loss. However, there is a significant lack of knowledge about dental trauma and the appropriate emergency procedures to handle these cases. The aim of this study was to evaluate the educational effect of notebook covers illustrated with figures and informative texts about tooth avulsion and replantation in sixth-grade primary school pupils. Sixth-grade pupils of two public school participated in this study. An experimental group consisting of 134 pupils received notebook covers illustrated with figures and informative texts about tooth avulsion and replantation, while a control group of 108 pupils received notebooks with neutral covers. An assessment of the educational effects on pupils was performed after 9 months, with a standardized questionnaire normally used to evaluate dental trauma. Statistical analysis was conducted with SPSS 21.0 (α = .05) for group description and comparison using chi-square and Student t tests. Compared with the control group, the experimental group showed statistically significant improvements in correct meaning of dental trauma (38% vs. 58.2%) procedures to follow in the case of dental avulsion (2.8% vs. 70.9%) storing the avulsed tooth in milk (18.5% vs. 76.9%) general knowledge about dental anatomy (61.1% vs. 95.5%) and the ideal time for the tooth to remain outside the mouth prior to replantation (20.4% vs. 59.7%). The use of notebook covers illustrated with figures and informative texts about dental trauma led to a significant increase in the knowledge of schoolchildren about tooth avulsion, first aid, and replantation.
Publisher: Medknow
Date: 2018
Publisher: Elsevier BV
Date: 06-2021
Publisher: Wiley
Date: 03-2021
DOI: 10.1002/RMV.2226
Abstract: The coronavirus disease 2019 (Covid‐19) is a viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) that clinically affects multiple organs of the human body. Cells in the oral cavity express viral entry receptor angiotensin‐converting enzyme 2 that allows viral replication and may cause tissue inflammation and destruction. Recent studies have reported that Covid‐19 patients present oral manifestations with multiple clinical aspects. In this review, we aim to summarise main signs and symptoms of Covid‐19 in the oral cavity, its possible association with oral diseases, and the plausible underlying mechanisms of hyperinflammation reflecting crosstalk between Covid‐19 and oral diseases. Ulcers, blisters, necrotising gingivitis, opportunistic coinfections, salivary gland alterations, white and erythematous plaques and gustatory dysfunction were the most reported clinical oral manifestations in patients with Covid‐19. In general, the lesions appear concomitant with the loss of smell and taste. Multiple reports show evidences of necrotic/ulcerative gingiva, oral blisters and hypergrowth of opportunistic oral pathogens. SARS‐CoV‐2 exhibits tropism for endothelial cells and Covid‐19‐mediated endotheliitis can not only promote inflammation in oral tissues but can also facilitate virus spread. In addition, elevated levels of proinflammatory mediators in patients with Covid‐19 and oral infectious disease can impair tissue homeostasis and cause delayed disease resolution. This suggests potential crosstalk of immune‐mediated pathways underlying pathogenesis. Interestingly, few reports suggest recurrent herpetic lesions and higher bacterial growth in Covid‐19 subjects, indicating SARS‐CoV‐2 and oral virus/bacteria interaction. Larger cohort studies comparing SARS‐CoV‐2 negative and positive subjects will reveal oral manifestation of the virus on oral health and its role in exacerbating oral infection.
Publisher: FapUNIFESP (SciELO)
Date: 2021
DOI: 10.1590/2177-6709.26.3.E2119251.OAR
Abstract: ABSTRACT Objective: This study aimed to evaluate the dimensional stability and maintenance of details of conventional and high stability alginates up to 5-day storage. Methods: Two types of alginates were selected (n=10) for this study, conventional (Hydrogum) and high stability alginates (Hydrogum 5), which were produced with the aid of a cylindrical metal block and a ring-shaped metal mold (Specifications 18, 19, and 25, ANSI/ADA). Ten images were obtained from the molds for the dimensional stability test, which were taken immediately after their production and at each different storage periods (15 min, 24 h, 48 h, 72 h, 96 h, and 120 h) by a digital camera. The specimens were kept hermetically sealed in plastic bags (23°C) and then used to obtain 140 (n=70) dental stone models, used in the detail reproduction test, in which the angular accuracy of three grooves (20 µm, 50 µm, and 75 µm) was observed at each period. The details reproduction accuracy was classified using a predetermined score classification. Measurements of dimensional changes were made in the Corel DRAW X6 program. The data were submitted to the Student’s t-test (α?#8197 = 0.05). Results: A statistically significant difference concerning the size of the matrix was observed after 24h for both alginates, and a statistically significant negative linear dimensional change (contraction) was verified after 24 h of storage (1.52% for the high stability alginate, and 1.32% for the conventional alginate). The high stability alginate kept the full details for 72 hours, while the conventional alginate, for 24 h. Both alginates reproduced the 75 µm groove at all storage periods. Conclusion: Impressions made with both alginates presented satisfactory clinical results when the alginates were immediately poured.
Publisher: FapUNIFESP (SciELO)
Date: 04-2005
DOI: 10.1590/S0103-64402005000100011
Abstract: The purpose of this study was to investigate the effects of cigarette smoke on the development of the embryo mandible (Meckel's) cartilage in rat fetuses. When inhaled by female Wistar rats between the 9th and the 12th day of pregnancy, cigarette smoke (5 cigarettes a day) caused intrauterine growth retardation, providing smaller fetuses and placentas. In fetuses from the experimental group, the histopathologic examination revealed a poorly developed Meckel's cartilage with smaller chondroblasts showing a scanty cytoplasm with spherical and paler central nuclei, as well as more abundant cartilage matrix. Morphometric analysis revealed that Meckel's cartilage lacunae were smaller in the fetuses from the experimental group, although not showing any remarkable alteration in shape. The results suggested that inhalation of cigarette smoke by pregnant rats during the organogenic period induced growth retardation and delayed cellular differentiation in rat fetal Meckel's cartilage.
Publisher: Wiley
Date: 28-10-2005
DOI: 10.1111/J.1600-9657.2005.00327.X
Abstract: The aim of the present study was to assess the level of knowledge of undergraduates from the College of Physical Education (Toledo, Araçatuba) concerning dental avulsion injuries. Data showed that 95% of the respondents did not know what dental avulsion is, 73.5% said they know how to define dental replantation, however, only 26% were able to do it correctly. When asked about first emergency measures after an avulsion, 50% of the respondents said they know what they should do, and the most cited measure was to seek a dentist. When asked about optimal storage media, 45.5% would keep it in a favorable one, and 28% did not know where to keep the tooth until treatment. Only 25.6% indicated a suitable extra-oral time for replantation 90.3% of the respondents had received no advice about the emergency management of dental avulsion 90% said they consider this an important and necessary subject. The results indicated that educational c aigns are necessary to improve the emergency management of dental injuries by those future P.E. professors for a better prognosis of dental replantation.
Publisher: Research, Society and Development
Date: 06-08-2020
Abstract: O objetivo deste estudo é apresentar uma análise retrospectiva de 20 anos dos casos de pacientes pediátricos acometidos por traumas facias, atendidos pela equipe de Cirurgia e Traumatologia Bucomaxilofacial da Faculdade de Odontologia de Araçatuba UNESP, Brazil, e mostrar a incidência desses tipos de trauma, assim como fatores etiológicos mais comuns, idade e sexo de pacientes pediátricos que sofreram algum tipo de fratura e mostrar como as característcas socias e culturais da papulação alteram diretamente a epidemiologia dessas moléstias em determinada região. Para tanto, foi realizado levantamento retrospectivo nos registros médicos de pacientes com até 12 anos de idade, de acordo com os critérios de elegibilidade adotados pelo estudo, em um período de 20 anos. O teste do qui-quadrado foi utilizado para comparar os grupos e a correlação de Pearson para verificar a associação entre as variáveis. Dos 312 prontuários analisados, as fraturas faciais foram registradas em 263 (84%), evidenciando uma alta incidência de fraturas na população estudada, sendo que a maioria delas ocorreu no sexo masculino e a principal fonte de trauma foi relacionada a eventos de alto impacto, como acidentes de trânsito, que causaram a prevalência de fraturas no terço médio da face. Dessa forma, é possível concluir que a morbimortalidade infantil por trauma maxilofacial foi alta em nosso estudo, mas vale ressaltar que esses números podem ser reduzidos com medidas de educação e segurança no trânsito, tanto para crianças quanto para adultos, os verdadeiros responsáveis por essa casuística.
Publisher: Wiley
Date: 06-2008
DOI: 10.1111/J.1600-9657.2008.00555.X
Abstract: The time elapsed between a trauma and tooth replantation usually ranges from 1 to 4 h. The chances of root surface damage are higher when tooth replantation is not performed immediately or if the avulsed tooth is not stored in an adequate medium. This invariably leads to necrosis of pulp tissue, periodontal ligament cells and cementum, thus increasing the possibility of root resorption, which is the main cause of loss of replanted teeth. This paper presents a comprehensive review of literature on root surface treatments performed in cases of delayed tooth replantation with necrotic cemental periodontal ligament. Journal articles retrieved from PubMed/MedLine, Bireme and Scielo databases were reviewed. It was observed that, when there are no periodontal ligament remnants and contamination is under control, replacement resorption and ankylosis are the best results and that, although these events will end up leading to tooth loss, this will happen slowly with no loss of the alveolar ridge height, which is important for future prosthesis planning.
Publisher: FapUNIFESP (SciELO)
Date: 09-2008
DOI: 10.1590/S1806-83242008000300007
Abstract: The purpose of this retrospective study was to analyze the cases of traumatic dental injuries involving root fracture and/or periodontal ligament injury (except avulsion) treated at the Discipline of Integrated Clinic, School of Dentistry of Araçatuba, São Paulo State University (UNESP), Brazil, from January 1992 to December 2002. Clinical and radiographic records from 161 patients with 287 traumatized teeth that had sustained root fracture and/or injuries to the periodontal ligament were examined. The results of this survey revealed that subluxation (25.09%) was the most common type of periodontal ligament injury, followed by extrusive luxation (19.86%). There was a predominance of young male patients and most of them did not present systemic alterations. Among the etiologic factors, the most frequent causes were falls and bicycle accidents. Injuries on extraoral soft tissues were mostly laceration and abrasion, while gingival and lip mucosa lacerations prevailed on intraoral soft tissues injuries. Radiographically, the most common finding was an increase of the periodontal ligament space. The most commonly performed treatment was root canal therapy. Within the limits of this study, it can be concluded that traumatic dental injuries occur more frequently in young male in iduals, due to falls and bicycle accidents. Subluxation was the most common type of periodontal ligament injury. Root canal therapy was the type of treatment most commonly planned and performed.
Publisher: APESB (Associacao de Apoio a Pesquisa em Saude Bucal)
Date: 08-2009
Publisher: Research, Society and Development
Date: 03-09-2020
Abstract: Carbonic anhydrase II (CA II) is involved with the acid-base homeostasis of tissue. This study aims to evaluate the effect of traumatic dental occlusion (TDO) by means of CA II expression in osteoclasts and osteocytes (near the lamina dura and in the centre of alveolar bone septum), in the periodontal ligament (PDL) and in lining cells (periosteum). For this study, 50 male Wistar rats aged seven weeks were ided into 2 groups: Loaded and Unloaded group. The study periods were 2, 5, 7, 14 and 21 days. The Mann-Whitney U test for quantitative, and the Chi-square test for semi-quantitative analyses were used for group comparison, along with Bonferroni’s post-hoc test. Statistically significant differences between the groups were observed in the number of osteoclasts in the lamina dura (days 5, 7 and 21) the alveolar bone septum (days 2 and 7) osteocytes near the lamina dura (days 2, 5, 7 and 14) and in the centre of the alveolar bone septum (days 2, 5, 7 and 14). There were also differences between-group in CA II expression in the lining cells on days 7 and 14. TDO increases CA II expression in osteoclasts, osteocytes, the PDL and lining cells of the periosteum. Clinical Relevance: Traumatic dental occlusion stimulates higher cells activity of the alveolar bone at short (lamina dura) and long (centre of alveolar bone and periosteum) distances.
Publisher: Wiley
Date: 06-03-2009
DOI: 10.1111/J.1600-9657.2008.00724.X
Abstract: Root fractures are defined as those that involve cement, dentin and pulp, comprising from 0.5 to 7% of injuries in permanent dentition. Diagnosis is made through clinical and radiographic exams, the latter frequently being limited by the position of the fracture. Treatment varies according to the displacement and vitality of the fragments. The authors present a clinical case of recurrent trauma of tooth 21 causing a horizontal root fracture in the middle third. After several attempts at endodontic treatment, the option was to remove the apical fragment by surgery. The postoperative period of 4 years shows very satisfactory results with regard to wound repair and tooth mobility, or implantation of the coronal segment.
Publisher: FapUNIFESP (SciELO)
Date: 2022
Abstract: Resumo Introdução As disfunções temporomandibulares apresentam uma variedade de sinais e sintomas que afetam a articulação temporomandibular, músculos da mastigação e estruturas relacionadas e muitos pacientes apresentam queixas cervicais. Objetivo Verificar a correlação de dor à palpação dos músculos da mastigação (masseter, temporal anterior, pterigoideos lateral e medial) e digástrico, com a queixa de dor no pescoço verificar a correlação de dor à palpação nos músculos da mastigação e digástrico, com dor à palpação no esternocleidomastoideo e trapézio, e se a força de correlação é diferente entre eles. Material e método Foram avaliados 232 prontuários da clínica odontológica das Disfunções Temporomandibulares da Faculdade de Odontologia de Araçatuba, do período de 2011 a 2013. Os dados coletados foram submetidos à análise estatística, com alfa (α) = 0.01 para todos os casos, exceto digástrico quando associado ao trapézio (α) = 0.05. Resultado A maioria dos pacientes era do sexo feminino. Houve correlação positiva entre dor à palpação nos músculos temporal, masseter, pterigoideo lateral, esternocleidomastoideo e trapézio, e queixa de dor no pescoço. Também houve correlação positiva entre a dor em todos os músculos da mastigação (masseter, temporal, pterigoideo lateral e medial) e digástrico e a dor no esternocleidomastoideo. Bem como a correlação de presença de dor nos músculos masseter, temporal, pterigoideo lateral e digástrico com dor no trapézio. A correlação de dor foi mais forte para o músculo esternocleidomastoideo, exceto para o pterigoideo lateral. Conclusão Existe correlação positiva entre a queixa de dor à palpação nos músculos da mastigação, exceto pterigiodeo medial, e os músculos cervicais (esternocleidomastoideo e trapézio). A força de correlação entre a dor do masseter e temporal anterior com o esternocleidomastoideo é mais forte do que com o trapézio.
Publisher: FapUNIFESP (SciELO)
Date: 03-2018
DOI: 10.1590/1807-3107/2018.VOL32.0007
Abstract: The aim of this study is to evaluate the action of paramonochlorophenol associated with Furacin followed by calcium hydroxide (CH) dressing in the control of inflammatory root resorption in cases of immediate tooth replantation with delayed endodontic treatment. A total of 28 incisors of 3 male dogs were extracted and replanted after 15 minutes, and randomly ided into 3 groups: Group I (n = 8) - endodontic treatment was performed before the extraction and replantation Group II (n = 10) - endodontic treatment was performed 30 days after replantation and the root canal was filled with CH dressing Group III (n = 10) - endodontic treatment was performed 30 days after replantation and root canals received temporary medication of paramonochlorophenol-Furacin followed by CH dressing. The animals were euthanized 90 days after replantation. The histomorphological events analyzed at the epithelial reattachment site were the intensity and extent of acute and chronic inflammatory processes, periodontal ligament (PDL) organization, the intensity and extent of acute and chronic inflammatory processes in the PDL space, root resorption, bone tissue, and ankylosis. Data were submitted to the Wilcoxon Signed Ranks Test for group comparison (α = 5%). In Groups I, II and III the periodontal ligament was regenerated and most of the resorption areas were repaired by newly formed cementum. The depth and extent of root resorption were significantly higher in Group II than in Group III. The use of paramonochlorophenol-furacin followed by CH dressing was more effective in controlling inflammatory root resorption after immediate tooth replantation.
Publisher: Elsevier BV
Date: 11-2012
Publisher: Research, Society and Development
Date: 03-07-2020
Abstract: The prognosis of dental trauma depends on professionals with solid and updated knowledge. The objective was to evaluate the ability of undergraduate dentistry students to develop treatment plans for dental trauma. This cross-sectional, observational, quantitative study had a s le of 242 participants. A clinical case involving avulsion of tooth 11 and complex coronary root fracture of tooth 21 was selected. All data relating to the patient's exams were added to a clinical record, which was delivered to students in the final year of the undergraduate dentistry course for three years consecutive. The students were instructed to develop a treatment plan for this case. The factors most considered in avulsion treatment plans were: how, when and where the trauma occurred, the patient's age and systemic condition. Of the students, 39.7% developed an adequate treatment plan, the main mistake being the lack of occlusal adjustment. In addition, 9,9% of students had an adequate treatment plan for coronary artery fracture. The recovery of periodontal biological space and the indication of intraradicular retainers were the main difficulties. It is concluded that undergraduate dentistry students had great difficulty in formulating treatment plans suitable for more severe cases of dentoalveolar trauma involving several specialties.
Publisher: FapUNIFESP (SciELO)
Date: 07-05-2018
Publisher: Wiley
Date: 10-04-2017
DOI: 10.1111/EDT.12330
Abstract: Traumatic occlusion (TO) can cause morphofunctional alterations that interfere in the homeostasis of the periodontium. The aim of this study was to assess the influence of TO on the periodontal repair process for teeth following subluxation. Ninety Wistar rats aged 12 weeks were ided into three groups: control (C), subluxation (S) and subluxation with traumatic occlusion (S+TO). Subluxation was created with an impact force of 900 cN applied by a tensiometer and TO was created with a direct composite resin filling. Healing after two experimental periods of 7 and 21 days was assessed histologically. The Kruskal-Wallis and Dunn post hoc tests were used for group comparison. At 7 days, there was a significant increase in periodontal ligament (PDL) width and amorphous fundamental substance, as well as a significant bone area reduction in groups S and S+TO. After 21 days, there was a significant PDL width increase in group S+TO, and in the percentage of collagen fibres in group S, whereas group S+TO showed a 52% bone area reduction compared to the same group at 7 days. Subluxation with or without TO caused only superficial root resorption. However, only group S+TO showed damage to the repair process of resorbed root areas after 21 days. TO can increase damage to the PDL after subluxation and it can also delay the repair process after PDL damage.
Location: Brazil
No related grants have been discovered for Daniela Atili Brandini.