ORCID Profile
0000-0002-6169-8049
Current Organisation
University College London
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Publisher: Wiley
Date: 15-05-2017
DOI: 10.1111/DME.13335
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 06-2015
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 25-08-2015
Abstract: Short‐term risk assessment tools for prediction of cardiovascular disease events are widely recommended in clinical practice and are used largely for single time‐point estimations however, persons with low predicted short‐term risk may have higher risks across longer time horizons. We estimated short‐term and lifetime cardiovascular disease risk in a pooled population from 2 studies of Peruvian populations. Short‐term risk was estimated using the atherosclerotic cardiovascular disease Pooled Cohort Risk Equations. Lifetime risk was evaluated using the algorithm derived from the Framingham Heart Study cohort. Using previously published thresholds, participants were classified into 3 categories: low short‐term and low lifetime risk, low short‐term and high lifetime risk , and high short‐term predicted risk . We also compared the distribution of these risk profiles across educational level, wealth index, and place of residence. We included 2844 participants (50% men, mean age 55.9 years [ SD 10.2 years]) in the analysis. Approximately 1 of every 3 participants (34% [95% CI 33 to 36]) had a high short‐term estimated cardiovascular disease risk. Among those with a low short‐term predicted risk, more than half (54% [95% CI 52 to 56]) had a high lifetime predicted risk. Short‐term and lifetime predicted risks were higher for participants with lower versus higher wealth indexes and educational levels and for those living in urban versus rural areas ( P .01). These results were consistent by sex. These findings highlight potential shortcomings of using short‐term risk tools for primary prevention strategies because a substantial proportion of Peruvian adults were classified as low short‐term risk but high lifetime risk. Vulnerable adults, such as those from low socioeconomic status and those living in urban areas, may need greater attention regarding cardiovascular preventive strategies.
Publisher: Ubiquity Press, Ltd.
Date: 03-2016
Location: Peru
Location: Spain
Location: Peru
Location: Peru
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Juan Carlos Bazo-Alvarez.