ORCID Profile
0000-0002-7033-5995
Current Organisation
Universidade Federal Rural do Rio de Janeiro
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Publisher: Universidade Estadual de Londrina
Date: 07-06-2019
DOI: 10.5433/1679-0359.2019V40N4P1489
Abstract: Anti-Müllerian Hormone (AMH) is a protein expressed in the gonads and related to ovarian follicular development. The aim of this study was to investigate the presence of polymorphisms in the AMH gene in a Nelore herd to analyze the genetic constitution of this population and to perform association studies with early pregnancy occurrence (EPO) and age at first calving (AFC). Phenotypic data consisted of verification of early pregnancy and age at first calving of 197 unrelated heifers exposed to the mating season and aged between 15 and 17 months (precocious group) and 24 months (non-precocious group). The "precocious" group consisted of 67 heifers with age at first calving of 26.5 ± 0.59 months, and the "non-precocious" group was composed of 130 heifers with age at first calving of 36.4 ± 0.99 months. All five exons of the AMH gene were lified by Polymerase Chain Reaction (PCR) and sequenced. A total of three SNPs were identified in this study, all of them located in exon 5 (rs527023314, rs722016629, and rs134387246), the latter one positioned in the stop codon. All three SNPs identified in exon 5 characterized synonymous mutations. Only SNP rs134387246 exhibited a significant value (P ? 0.10) for EPO and AFC. The association study of SNP rs134387246 revealed an over-dominance effect (P = 0.056), and no additive effect was observed (P = 0.67). A reduction of 2.5 months (75 days) in the age at first calving of heterozygous heifers for the SNP rs134387246 was observed. For the first time, polymorphisms of the AMH gene were described in Nelore heifers and associated with sexual precocity traits.
Publisher: Springer Science and Business Media LLC
Date: 19-08-2015
Publisher: Public Library of Science (PLoS)
Date: 05-08-2016
Publisher: Springer Science and Business Media LLC
Date: 21-06-2016
Publisher: Springer Science and Business Media LLC
Date: 17-09-2015
Publisher: Frontiers Media SA
Date: 20-03-2018
Publisher: Elsevier BV
Date: 09-2017
Publisher: Public Library of Science (PLoS)
Date: 02-01-2018
Publisher: Springer Science and Business Media LLC
Date: 28-07-2016
DOI: 10.1007/S11250-016-1110-X
Abstract: This study identified polymorphisms in the DGAT1 gene in Murrah buffaloes and investigated the associations to milk production and quality traits (milk, fat and protein yields and percentages, somatic cell count). Genomic DNA was extracted from hair follicles collected from the tail of 196 females. Three SNPs were identified in DGAT1 gene by sequencing. Statistical analyses were performed to verify the linkage and the association between polymorphisms and traits. The estimated value of r (2) between two SNPs in exon 17 (g.11,783G > A and g.11,785 T > C) was 0.029. SNP g.11,785 T > C was significantly associated (P < 0.05) to fat and protein percentage. Dominance effect was significant for milk and fat yields and protein percentage (P C was significant for protein production and somatic cell count (P < 0.05). It indicates that assisted marker selection might be done with considerations to balance production and udder health.
Location: Brazil
No related grants have been discovered for Marina Mortati Dias Barbero.