ORCID Profile
0000-0002-8195-5057
Current Organisations
Nankai University
,
Western Norway University of Applied Sciences
,
University of Adelaide
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Publisher: Springer Science and Business Media LLC
Date: 12-2020
DOI: 10.1140/EPJC/S10052-020-08477-8
Abstract: The jet energy scale, jet energy resolution, and their systematic uncertainties are measured for jets reconstructed with the ATLAS detector in 2012 using proton–proton data produced at a centre-of-mass energy of 8 TeV with an integrated luminosity of $$20 \\, \\hbox {fb}^{-1}$$ 20 fb - 1 . Jets are reconstructed from clusters of energy depositions in the ATLAS calorimeters using the anti- $$k_t$$ k t algorithm. A jet calibration scheme is applied in multiple steps, each addressing specific effects including mitigation of contributions from additional proton–proton collisions, loss of energy in dead material, calorimeter non-compensation, angular biases and other global jet effects. The final calibration step uses several in situ techniques and corrects for residual effects not captured by the initial calibration. These analyses measure both the jet energy scale and resolution by exploiting the transverse momentum balance in $$\\gamma $$ γ + jet, Z + jet, dijet, and multijet events. A statistical combination of these measurements is performed. In the central detector region, the derived calibration has a precision better than 1% for jets with transverse momentum $$150 \\, \\hbox {GeV} p_{{\\mathrm {T}}} $$ 150 GeV p T 1500 GeV, and the relative energy resolution is $$(8.4\\pm 0.6)\\%$$ ( 8.4 ± 0.6 ) % for $$p_{{\\mathrm {T}}}= 100 \\, \\hbox {GeV}$$ p T = 100 GeV and $$(23\\pm 2)\\%$$ ( 23 ± 2 ) % for $$p_{{\\mathrm {T}}}= 20 \\, \\hbox {GeV}$$ p T = 20 GeV . The calibration scheme for jets with radius parameter $$R=1.0$$ R = 1.0 , for which jets receive a dedicated calibration of the jet mass, is also discussed.
Publisher: OMICS Publishing Group
Date: 2013
Publisher: Sissa Medialab
Date: 27-06-2019
DOI: 10.22323/1.352.0135
Publisher: JMIR Publications Inc.
Date: 13-04-2021
DOI: 10.2196/27275
Abstract: Although the potential of big data analytics for health care is well recognized, evidence is lacking on its effects on public health. The aim of this study was to assess the impact of the use of big data analytics on people’s health based on the health indicators and core priorities in the World Health Organization (WHO) General Programme of Work 2019/2023 and the European Programme of Work (EPW), approved and adopted by its Member States, in addition to SARS-CoV-2–related studies. Furthermore, we sought to identify the most relevant challenges and opportunities of these tools with respect to people’s health. Six databases (MEDLINE, Embase, Cochrane Database of Systematic Reviews via Cochrane Library, Web of Science, Scopus, and Epistemonikos) were searched from the inception date to September 21, 2020. Systematic reviews assessing the effects of big data analytics on health indicators were included. Two authors independently performed screening, selection, data extraction, and quality assessment using the AMSTAR-2 (A Measurement Tool to Assess Systematic Reviews 2) checklist. The literature search initially yielded 185 records, 35 of which met the inclusion criteria, involving more than 5,000,000 patients. Most of the included studies used patient data collected from electronic health records, hospital information systems, private patient databases, and imaging datasets, and involved the use of big data analytics for noncommunicable diseases. “Probability of dying from any of cardiovascular, cancer, diabetes or chronic renal disease” and “suicide mortality rate” were the most commonly assessed health indicators and core priorities within the WHO General Programme of Work 2019/2023 and the EPW 2020/2025. Big data analytics have shown moderate to high accuracy for the diagnosis and prediction of complications of diabetes mellitus as well as for the diagnosis and classification of mental disorders prediction of suicide attempts and behaviors and the diagnosis, treatment, and prediction of important clinical outcomes of several chronic diseases. Confidence in the results was rated as “critically low” for 25 reviews, as “low” for 7 reviews, and as “moderate” for 3 reviews. The most frequently identified challenges were establishment of a well-designed and structured data source, and a secure, transparent, and standardized database for patient data. Although the overall quality of included studies was limited, big data analytics has shown moderate to high accuracy for the diagnosis of certain diseases, improvement in managing chronic diseases, and support for prompt and real-time analyses of large sets of varied input data to diagnose and predict disease outcomes. International Prospective Register of Systematic Reviews (PROSPERO) CRD42020214048 www.crd.york.ac.uk rospero/display_record.php?RecordID=214048
Publisher: BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
Date: 17-09-2017
Publisher: Springer Science and Business Media LLC
Date: 10-2020
DOI: 10.1140/EPJC/S10052-020-8223-0
Abstract: Inclusive and differential fiducial cross sections of the Higgs boson are measured in the $$H \\rightarrow ZZ^{*} \\rightarrow 4\\ell $$ H → Z Z ∗ → 4 ℓ ( $$\\ell = e,\\mu $$ ℓ = e , μ ) decay channel. The results are based on proton-proton collision data produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector from 2015 to 2018, equivalent to an integrated luminosity of 139 $$\\hbox {fb}^{-1}$$ fb - 1 . The inclusive fiducial cross section for the $$H \\rightarrow ZZ^{*} \\rightarrow 4\\ell $$ H → Z Z ∗ → 4 ℓ process is measured to be $$\\sigma _\\mathrm {fid} = 3.28 \\,{\\pm }\\, 0.32$$ σ fid = 3.28 ± 0.32 fb, in agreement with the Standard Model prediction of $$\\sigma _\\mathrm {fid, SM} = 3.41 \\pm 0.18 $$ σ fid , SM = 3.41 ± 0.18 fb. Differential fiducial cross sections are measured for a variety of observables which are sensitive to the production and decay of the Higgs boson. All measurements are in agreement with the Standard Model predictions. The results are used to constrain anomalous Higgs boson interactions with Standard Model particles.
Publisher: Springer Science and Business Media LLC
Date: 08-2020
DOI: 10.1140/EPJC/S10052-020-8050-3
Abstract: The results of a search for electroweakino pair production $$pp \\rightarrow \\tilde{\\chi }^\\pm _1 \\tilde{\\chi }^0_2$$ p p → χ ~ 1 ± χ ~ 2 0 in which the chargino ( $$\\tilde{\\chi }^\\pm _1$$ χ ~ 1 ± ) decays into a W boson and the lightest neutralino ( $$\\tilde{\\chi }^0_1$$ χ ~ 1 0 ), while the heavier neutralino ( $$\\tilde{\\chi }^0_2$$ χ ~ 2 0 ) decays into the Standard Model 125 GeV Higgs boson and a second $$\\tilde{\\chi }^0_1$$ χ ~ 1 0 are presented. The signal selection requires a pair of b -tagged jets consistent with those from a Higgs boson decay, and either an electron or a muon from the W boson decay, together with missing transverse momentum from the corresponding neutrino and the stable neutralinos. The analysis is based on data corresponding to 139 $$\\mathrm {fb}^{-1}$$ fb - 1 of $$\\sqrt{s}=13$$ s = 13 TeV pp collisions provided by the Large Hadron Collider and recorded by the ATLAS detector. No statistically significant evidence of an excess of events above the Standard Model expectation is found. Limits are set on the direct production of the electroweakinos in simplified models, assuming pure wino cross-sections. Masses of $$\\tilde{\\chi }^{\\pm }_{1}/\\tilde{\\chi }^{0}_{2}$$ χ ~ 1 ± / χ ~ 2 0 up to 740 GeV are excluded at 95% confidence level for a massless $$\\tilde{\\chi }^{0}_{1}$$ χ ~ 1 0 .
Publisher: MDPI AG
Date: 30-03-2020
DOI: 10.3390/JCM9040941
Abstract: A growing body of literature on the 2019 novel coronavirus (SARS-CoV-2) is becoming available, but a synthesis of available data has not been conducted. We performed a scoping review of currently available clinical, epidemiological, laboratory, and chest imaging data related to the SARS-CoV-2 infection. We searched MEDLINE, Cochrane CENTRAL, EMBASE, Scopus and LILACS from 01 January 2019 to 24 February 2020. Study selection, data extraction and risk of bias assessment were performed by two independent reviewers. Qualitative synthesis and meta-analysis were conducted using the clinical and laboratory data, and random-effects models were applied to estimate pooled results. A total of 61 studies were included (59,254 patients). The most common disease-related symptoms were fever (82%, 95% confidence interval (CI) 56%–99% n = 4410), cough (61%, 95% CI 39%–81% n = 3985), muscle aches and/or fatigue (36%, 95% CI 18%–55% n = 3778), dyspnea (26%, 95% CI 12%–41% n = 3700), headache in 12% (95% CI 4%–23%, n = 3598 patients), sore throat in 10% (95% CI 5%–17%, n = 1387) and gastrointestinal symptoms in 9% (95% CI 3%–17%, n = 1744). Laboratory findings were described in a lower number of patients and revealed lymphopenia (0.93 × 109/L, 95% CI 0.83–1.03 × 109/L, n = 464) and abnormal C-reactive protein (33.72 mg/dL, 95% CI 21.54–45.91 mg/dL n = 1637). Radiological findings varied, but mostly described ground-glass opacities and consolidation. Data on treatment options were limited. All-cause mortality was 0.3% (95% CI 0.0%–1.0% n = 53,631). Epidemiological studies showed that mortality was higher in males and elderly patients. The majority of reported clinical symptoms and laboratory findings related to SARS-CoV-2 infection are non-specific. Clinical suspicion, accompanied by a relevant epidemiological history, should be followed by early imaging and virological assay.
Publisher: Springer Science and Business Media LLC
Date: 28-07-2022
DOI: 10.1186/S12888-022-04158-W
Abstract: The COVID-19 pandemic has exacerbated the risk factors associated with suicidal behavior and thus, prioritizing its prevention is recommended. This study systematically reviewed the global evidence on the incidence of suicide/suicidal attempts and the trend in suicidal rates during the COVID-19 pandemic. Cross-sectional and cohort studies investigating the outcomes of suicidal death and suicidal attempts at any setting during the COVID-19 pandemic were searched in Medline, Embase, and PsycINFO databases for papers published from December 2019 to May 2021. Out of 1052 studies18 studies with 12,746 suicidal attempts and 33,345 suicidal deaths were included in the final analysis. The mental health impact of social distancing, COVID-19 quarantine, and financial crises due to loss of employment were associated risk factors with suicide and/or suicidal attempts during the COVID-19 pandemic. Six common thematic recommendations for preventing suicidal deaths and suicidal attempts were identified. Unexpected behavior changes during the COVID-19 pandemic may have contributed to the increasing trend of suicidal attempts reported. Domestic conflicts and violence, financial loss, anxiety and depression, and pre-existing mental health condition/s should be considered in preventing suicidal attempts and deaths secondary to the COVID 19 pandemic. Early detection and timely intervention for in iduals with suicidal behavior is crucial and collated recommendations in the current study can be utilized for those preventive interventions. More systematic suicide risk screening process should be introduced who are at risk, along with an evidence base prevention approach.
Publisher: Springer Science and Business Media LLC
Date: 10-2020
DOI: 10.1140/EPJC/S10052-020-8227-9
Abstract: Higgs boson properties are studied in the four-lepton decay channel (where lepton = e , $$\\mu $$ μ ) using 139 $$\\hbox {fb}^{-1}$$ fb - 1 of proton–proton collision data recorded at $$\\sqrt{s}=$$ s = 13 TeV by the ATLAS experiment at the Large Hadron Collider. The inclusive cross-section times branching ratio for $$H\\rightarrow ZZ^*$$ H → Z Z ∗ decay is measured to be $$1.34 \\pm 0.12$$ 1.34 ± 0.12 pb for a Higgs boson with absolute rapidity below 2.5, in good agreement with the Standard Model prediction of $$1.33 \\pm 0.08$$ 1.33 ± 0.08 pb. Cross-sections times branching ratio are measured for the main Higgs boson production modes in several exclusive phase-space regions. The measurements are interpreted in terms of coupling modifiers and of the tensor structure of Higgs boson interactions using an effective field theory approach. Exclusion limits are set on the CP-even and CP-odd ‘beyond the Standard Model’ couplings of the Higgs boson to vector bosons, gluons and top quarks.
Publisher: Springer Science and Business Media LLC
Date: 07-2020
DOI: 10.1140/EPJC/S10052-020-8001-Z
Abstract: This paper describes precision measurements of the transverse momentum $$p_\\mathrm {T}^{\\ell \\ell }$$ p T ℓ ℓ ( $$\\ell =e,\\mu $$ ℓ = e , μ ) and of the angular variable $$\\phi ^{*}_{\\eta }$$ ϕ η ∗ distributions of Drell–Yan lepton pairs in a mass range of 66–116 GeV. The analysis uses data from 36.1 fb $$^{-1}$$ - 1 of proton–proton collisions at a centre-of-mass energy of $$\\sqrt{s}=13\\,$$ s = 13 TeV collected by the ATLAS experiment at the LHC in 2015 and 2016. Measurements in electron-pair and muon-pair final states are performed in the same fiducial volumes, corrected for detector effects, and combined. Compared to previous measurements in proton–proton collisions at $$\\sqrt{s}=7$$ s = 7 and $$8\\,$$ 8 TeV, these new measurements probe perturbative QCD at a higher centre-of-mass energy with a different composition of initial states. They reach a precision of 0.2 $$\\%$$ % for the normalized spectra at low values of $$p_\\mathrm {T}^{\\ell \\ell }$$ p T ℓ ℓ . The data are compared with different QCD predictions, where it is found that predictions based on resummation approaches can describe the full spectrum within uncertainties.
Publisher: MDPI AG
Date: 28-03-2023
DOI: 10.3390/NU15071649
Abstract: Glucose is a vital fuel for fetal growth, and carbohydrates are the primary source of glucose in the diet. The effects of carbohydrate intake during pregnancy on neonatal birth weight have not been fully investigated or systematically reviewed. Therefore, this systematic review aimed to collate the available evidence to determine whether carbohydrate intake during pregnancy impacts newborn birth weight. A literature search was performed from inception to March 2022 in Embase, Medline, and PsycInfo. Articles published in English were independently screened for the title and abstracts, and then for full texts. Out of 17 studies included, a significant relationship between the intake of maternal carbohydrate or its subcomponents and neonatal birth weight was reported in six studies. Of them, one study reported that higher carbohydrate intake in early pregnancy was associated with lower birth weight. The two other studies reported a positive correlation between maternal carbohydrate intake and neonatal birth weight regarding first- and second-trimester intake. Maternal carbohydrate intake may have an impact on birth weight, as suggested by the included studies in this systematic review. However, the overall review indicates contradictory findings concerning the relationship between carbohydrate intake and neonatal birth weight. Studies assessing the type of carbohydrate and the amount consumed with improved methodological quality are recommended.
Publisher: JMIR Publications Inc.
Date: 19-01-2021
Abstract: lthough the potential of big data analytics for health care is well recognized, evidence is lacking on its effects on public health. he aim of this study was to assess the impact of the use of big data analytics on people’s health based on the health indicators and core priorities in the World Health Organization (WHO) General Programme of Work 2019/2023 and the European Programme of Work (EPW), approved and adopted by its Member States, in addition to SARS-CoV-2–related studies. Furthermore, we sought to identify the most relevant challenges and opportunities of these tools with respect to people’s health. ix databases (MEDLINE, Embase, Cochrane Database of Systematic Reviews via Cochrane Library, Web of Science, Scopus, and Epistemonikos) were searched from the inception date to September 21, 2020. Systematic reviews assessing the effects of big data analytics on health indicators were included. Two authors independently performed screening, selection, data extraction, and quality assessment using the AMSTAR-2 (A Measurement Tool to Assess Systematic Reviews 2) checklist. he literature search initially yielded 185 records, 35 of which met the inclusion criteria, involving more than 5,000,000 patients. Most of the included studies used patient data collected from electronic health records, hospital information systems, private patient databases, and imaging datasets, and involved the use of big data analytics for noncommunicable diseases. “Probability of dying from any of cardiovascular, cancer, diabetes or chronic renal disease” and “suicide mortality rate” were the most commonly assessed health indicators and core priorities within the WHO General Programme of Work 2019/2023 and the EPW 2020/2025. Big data analytics have shown moderate to high accuracy for the diagnosis and prediction of complications of diabetes mellitus as well as for the diagnosis and classification of mental disorders prediction of suicide attempts and behaviors and the diagnosis, treatment, and prediction of important clinical outcomes of several chronic diseases. Confidence in the results was rated as “critically low” for 25 reviews, as “low” for 7 reviews, and as “moderate” for 3 reviews. The most frequently identified challenges were establishment of a well-designed and structured data source, and a secure, transparent, and standardized database for patient data. lthough the overall quality of included studies was limited, big data analytics has shown moderate to high accuracy for the diagnosis of certain diseases, improvement in managing chronic diseases, and support for prompt and real-time analyses of large sets of varied input data to diagnose and predict disease outcomes. nternational Prospective Register of Systematic Reviews (PROSPERO) CRD42020214048 www.crd.york.ac.uk rospero/display_record.php?RecordID=214048
Publisher: Springer International Publishing
Date: 30-08-2021
Publisher: Springer Science and Business Media LLC
Date: 03-05-2022
DOI: 10.1038/S41598-022-11034-W
Abstract: Primary dysmenorrhea (PD) is a common gynecological condition among adolescent and adult women. Several pharmacological and alternative therapies (e.g. therapeutic taping) have been used to treat PD, with varying effect. This systematic review and meta-analysis was performed to evaluate the safety and efficacy of therapeutic taping on clinical symptoms of PD, considering pain as the primary outcome. MEDLINE, Cochrane Library, Embase, PEDro, CINAHL and gray literature sources were searched from inception to February 2022 for randomized controlled trials (RCTs) that assessed the effect of therapeutic taping for PD. The language was restricted to English. A total of ten studies were included in the systematic review, involving 685 participants. Eight studies were included in quantitative analysis. The quality of the studies ranged from 4 to 7 with a median of 5 as assessed by PEDro scale. Meta-analyses indicated short-term improvements of pain compared to sham and no interventions. Elastic therapeutic taping (ETT) indicated short term improvements in anxiety associated with PD. Moderate to high quality of evidence suggested that ETT is an effective intervention in improving pain, anxiety, and quality of life of women with PD. A scarcity of evidence on the long-term effects of therapeutic taping in PD is observed.
Publisher: American Physical Society (APS)
Date: 21-09-2020
Publisher: Springer Science and Business Media LLC
Date: 27-08-2022
DOI: 10.1007/S00296-022-05194-1
Abstract: Literature searches are important components of systematic reviews. They are not only informative of the retrieval process, but they also set the data to be analyzed and influence additional components of systematic reviews. Despite the available guidelines, several studies have shown that the quality of reporting in systematic reviews is deficient in several medical fields. Systematic reviews may not comply completely with those guidelines despite explicitly stating they do. This protocol intends to answer to what extent systematic reviews published in rheumatology journals have complied with the PRISMA's search strategy guidelines published in 2009. The objective of the study is to analyze the compliance with the PRISMA (2009) search strategy guidelines among systematic reviews published in leading rheumatology journals. Inclusion criteria for this umbrella review protocol are systematic reviews (with or without meta-analyses) that mention having followed the PRISMA statement (2009) in their methods section, and published in journals listed in the Rheumatology category of the Journal of Citations Report 2020. Exclusion criteria are articles published before 2009 retraction letters, notes, expressions of concern systematic reviews using PRISMA 2020. Databases to be consulted are Web of Science, PubMed and Scopus, from inception to present. Data summaries will be presented in graphs, figures, tables and network maps. A narrative synthesis will be described. This protocol complies with guidelines such as PRISMA 2020, PRISMA-A, PRISMA-P, PRISMA-S, PRESS, and JBI Manual for evidence synthesis, as long as it is suitable for umbrella review protocols. Articles in any language will be considered.
Publisher: Elsevier BV
Date: 07-2018
Publisher: Informa UK Limited
Date: 17-07-2018
DOI: 10.1080/09593985.2018.1494233
Abstract: Hippotherapy is used to supplement conventional therapy in neurological conditions with evidence supporting its use in pediatric patients. However, evaluation of its merit in adults with acquired brain injury (ABI) is lacking. The aim of this study was to determine if hippotherapy can improve motor function in adults with ABI.
Publisher: Springer Science and Business Media LLC
Date: 06-2020
Publisher: American Physical Society (APS)
Date: 05-08-2020
Publisher: Springer Science and Business Media LLC
Date: 08-2020
DOI: 10.1140/EPJC/S10052-020-8102-8
Abstract: A search for direct pair production of scalar partners of the top quark (top squarks or scalar third-generation up-type leptoquarks) in the all-hadronic $$t{\\bar{t}}$$ t t ¯ plus missing transverse momentum final state is presented. The analysis of 139 $$\\hbox {fb}^{-1}$$ fb - 1 of $${\\sqrt{s}=13}$$ s = 13 TeV proton–proton collision data collected using the ATLAS detector at the LHC yields no significant excess over the Standard Model background expectation. To interpret the results, a supersymmetric model is used where the top squark decays via $${\\tilde{t}} \\rightarrow t^{(*)} {\\tilde{\\chi }}^0_1$$ t ~ → t ( ∗ ) χ ~ 1 0 , with $$t^{(*)}$$ t ( ∗ ) denoting an on-shell (off-shell) top quark and $${\\tilde{\\chi }}^0_1$$ χ ~ 1 0 the lightest neutralino. Three specific event selections are optimised for the following scenarios. In the scenario where $$m_{{\\tilde{t}}} m_t+m_{{\\tilde{\\chi }}^0_1}$$ m t ~ m t + m χ ~ 1 0 , top squark masses are excluded in the range 400–1250 GeV for $${\\tilde{\\chi }}^0_1$$ χ ~ 1 0 masses below 200 GeV at 95% confidence level. In the situation where $$m_{{\\tilde{t}}}\\sim m_t+m_{{\\tilde{\\chi }}^0_1}$$ m t ~ ∼ m t + m χ ~ 1 0 , top squark masses in the range 300–630 GeV are excluded, while in the case where $$m_{{\\tilde{t}}} m_W+m_b+m_{{\\tilde{\\chi }}^0_1}$$ m t ~ m W + m b + m χ ~ 1 0 (with $$m_{{\\tilde{t}}}-m_{{\\tilde{\\chi }}^0_1}\\ge 5$$ m t ~ - m χ ~ 1 0 ≥ 5 GeV), considered for the first time in an ATLAS all-hadronic search, top squark masses in the range 300–660 GeV are excluded. Limits are also set for scalar third-generation up-type leptoquarks, excluding leptoquarks with masses below 1240 GeV when considering only leptoquark decays into a top quark and a neutrino.
Publisher: Elsevier BV
Date: 2020
DOI: 10.2139/SSRN.3550028
Publisher: Springer Science and Business Media LLC
Date: 10-2020
Abstract: A search for a chargino-neutralino pair decaying via the 125 GeV Higgs boson into photons is presented. The study is based on the data collected between 2015 and 2018 with the ATLAS detector at the LHC, corresponding to an integrated luminosity of 139 fb − 1 of pp collisions at a centre-of-mass energy of 13 TeV. No significant excess over the expected background is observed. Upper limits at 95% confidence level for a massless $$ {\\tilde{\\chi}}_1^0 $$ χ ˜ 1 0 are set on several electroweakino production cross-sections and the visible cross-section for beyond the Standard Model processes. In the context of simplified supersymmetric models, 95% confidence-level limits of up to 310 GeV in $$ m\\left({\\tilde{\\chi}}_1^{\\pm }/{\\tilde{\\chi}}_2^0\\right) $$ m χ ˜ 1 ± / χ ˜ 2 0 , where $$ m\\left({\\tilde{\\chi}}_1^0\\right) $$ m χ ˜ 1 0 = 0 . 5 GeV, are set. Limits at 95% confidence level are also set on the $$ {\\tilde{\\chi}}_1^{\\pm }{\\tilde{\\chi}}_2^0 $$ χ ˜ 1 ± χ ˜ 2 0 cross-section in the mass plane of $$ m\\left({\\tilde{\\chi}}_1^{\\pm }/{\\tilde{\\chi}}_2^0\\right) $$ m χ ˜ 1 ± / χ ˜ 2 0 and $$ m\\left({\\tilde{\\chi}}_1^0\\right) $$ m χ ˜ 1 0 , and on scenarios with gravitino as the lightest supersymmetric particle. Upper limits at the 95% confidence-level are set on the higgsino production cross-section. Higgsino masses below 380 GeV are excluded for the case of the higgsino fully decaying into a Higgs boson and a gravitino.
Publisher: IOP Publishing
Date: 14-09-2020
Publisher: Springer Science and Business Media LLC
Date: 10-10-2021
DOI: 10.1186/S12874-021-01390-Y
Abstract: Recruitment to stroke clinical trials is challenging, but consumer registers can facilitate participation. Researchers need to understand the key factors that facilitate trial involvement and improve consumer partnerships to identify what research topics important to stroke and transient ischemic attack (TIA) survivors and their carers. We aimed to examine i) the experience of being involved in a stroke research register, and ii) the priorities for stroke research from the perspective of stroke survivors. Online and paper-based surveys were sent directly to members of a stroke register and disseminated online. Multiple choice questions were reported as counts and percentages and open-ended questions were thematically analysed using Braun and Clarke’s 6-stage process. Of 445 survey respondents, 154 (38%) were a member of the Stroke Research Register. The most frequently reported reason for research participation was to help others in the future. Respondents reported they were less likely to take part in research if the research question was not relevant to them, if transport was an issue, or because they lacked time. The most important research problems reported were targeting specific impairments including recovery of movement, fatigue, and aphasia, improvement of mental health services, and increased support for carers. Recruitment to trials may be improved by research registers if an inclusive research culture is fostered, in which consumers feel valued as members of a community, have direct and timely access to research findings and the opportunity to be meaningfully involved in research around the problems that consumers find most important.
Publisher: Springer Science and Business Media LLC
Date: 08-2020
Abstract: The factor of four increase in the LHC luminosity, from 0 . 5 × 10 34 cm − 2 s − 1 to 2 . 0 × 10 34 cm − 2 s − 1 , and the corresponding increase in pile-up collisions during the 2015–2018 data-taking period, presented a challenge for the ATLAS trigger, particularly for those algorithms that select events with missing transverse momentum. The output data rate at fixed threshold typically increases exponentially with the number of pile-up collisions, so the legacy algorithms from previous LHC data-taking periods had to be tuned and new approaches developed to maintain the high trigger efficiency achieved in earlier operations. A study of the trigger performance and comparisons with simulations show that these changes resulted in event selection efficiencies of 98% for this period, meeting and in some cases exceeding the performance of similar triggers in earlier run periods, while at the same time keeping the necessary bandwidth within acceptable limits.
Publisher: American Physical Society (APS)
Date: 27-07-2020
Publisher: Springer Science and Business Media LLC
Date: 11-2020
DOI: 10.1140/EPJC/S10052-020-08509-3
Abstract: A search is presented for four-top-quark production using an integrated luminosity of 139 fb $$^{-1}$$ - 1 of proton–proton collision data at a centre-of-mass energy of $$13~\\text {TeV}$$ 13 TeV collected by the ATLAS detector at the LHC. Events are selected if they contain a same-sign lepton pair or at least three leptons (electrons or muons). Jet multiplicity, jet flavour and event kinematics are used to separate signal from the background through a multivariate discriminant, and dedicated control regions are used to constrain the dominant backgrounds. The four-top-quark production cross section is measured to be $$24^{+7}_{-6}$$ 24 - 6 + 7 fb. This corresponds to an observed (expected) significance with respect to the background-only hypothesis of 4.3 (2.4) standard deviations and provides evidence for this process.
Publisher: Springer Science and Business Media LLC
Date: 07-2020
Abstract: A search for Higgs boson pair production via vector-boson fusion (VBF) in the $$ b\\overline{b}b\\overline{b} $$ b b ¯ b b ¯ final state is carried out with the ATLAS experiment using 126 fb − 1 of proton- proton collision data delivered at $$ \\sqrt{s} $$ s = 13 TeV by the Large Hadron Collider. This search is sensitive to VBF production of additional heavy bosons that may decay into Higgs boson pairs, and in a non-resonant topology it can constrain the quartic coupling between the Higgs bosons and vector bosons. No significant excess relative to the Standard Model expectation is observed, and limits on the production cross-section are set at the 95% confidence level for a heavy scalar resonance in the context of an extended Higgs sector, and for non-resonant Higgs boson pair production. Interpretation in terms of the coupling between a Higgs boson pair and two vector bosons is also provided: coupling values normalised to the Standard Model expectation of κ 2 V − 0 . 76 and κ 2 V 2 . 90 are excluded at the 95% confidence level in data.
Publisher: Springer Science and Business Media LLC
Date: 02-03-2023
DOI: 10.1186/S13643-022-02164-3
Abstract: Osteoarthritis (OA) and lower back pain (LBP) are most common health problems which lead to pain and disability. This study aimed to systematically review the evidence to find any relationship between knee osteoarthritis (KOA) and LBP or any potential causation. The databases of Scopus, MEDLINE, and Embase were searched from inception to 01 October 2022. Any study published in English assessing live humans over 18 years with KOA and LBP was eligible to be included. Studies were independently screened by two researchers. Data of the included studies were extracted based on the participants, outcomes related to knee and lumbar spine, reported association or causation between LBP and KOA, and study design. Data were narratively analyzed and presented as graphs and table. Methodology quality was assessed. Of 9953 titles and abstracts, duplicates were removed, and 7552 were screened. Altogether, 88 full texts were screened, and 13 were eligible for the final inclusion. There were some biomechanical and clinical causations were observed for the concurrent presence of LBP and KOA. Biomechanically, high pelvic incidence is a risk factor for development of spondylolisthesis and KOA. Clinically, knee pain intensity was higher in KOA when presents with LBP. Less than 20% of studies have justified their s le size during the quality assessment. Development and progression of KOA in patients with degenerative spondylolisthesis may be induced by significantly greater mismatches of lumbo-pelvic sagittal alignment. Elderly patients with degenerative lumbar spondylolisthesis and severe KOA reported a different pelvic morphology, increased sagittal malalignment with a lack of lumbar lordosis due to double-level listhesis, and greater knee flexion contracture than in patients with no to mild and moderate KOA. People with concurrent LBP and KOA have reported poor function with more disability. Both LBP and lumbar kyphosis indicate functional disability and knee symptoms in patients with KOA. Different biomechanical and clinical causations were revealed for the concurrent existence of KOA and LBP. Therefore, careful assessment of both back and knee joints should be considered when treating KOA and vice versa. PROSPERO CRD42022238571
Publisher: Wiley
Date: 02-08-2022
DOI: 10.1111/PAPR.13150
Abstract: To evaluate the exercise‐induced hypoalgesic (EIH) effects of different types of physical exercise in in iduals with neck pain. Systematic review with meta‐analysis. An electronic search of six databases was completed to include studies assessing EIH effects on neck pain. Randomized controlled trials, controlled trials, and observational studies that assessed before and immediate after‐effects of a single session of physical exercise in people with neck pain were included. Two reviewers independently screened records, extracted outcomes, assessed the risk of bias, and rated the quality of evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. EIH is characterized by increased pain threshold, pain tolerance, and/or decreased sensitivity to painful stimuli or unpleasantness, which may last up to 30 min after a single bout of exercise. EIH is usually measured with quantitative sensory testing (QST) and is mostly taken as the difference between pre‐ and postexercise pressure pain threshold (PPT). Data were pooled and analyzed using a fixed‐effect meta‐analysis. Eleven articles were included in this review nine with low risk of bias and two with some concerns about the risk of bias. Three studies with chronic whiplash‐associated disorders (WAD) were included in the meta‐analysis isometric exercise had a larger EIH effect at the local testing site compared with submaximal aerobic exercises (MD = −0.21, [95% CI = −0.43, 0.00], p = 0.05, I 2 = 92%), submaximal aerobic and isometric exercises had equal EIH effects at the remote testing site (MD = 0.01, [95% CI = −0.33, 0.35], p = 0.95, I 2 = 0%), and submaximal aerobic exercises exerted comparably larger EIH effect at the remote testing site than local testing site (MD = −0.01, [95% CI = −0.20, 0.18], p = 0.93, I 2 = 56%). The certainty of evidence (GRADE) for these analyses was low to very low. According to the descriptive analysis of the studies of chronic nonspecific neck pain, isometric and range of motion (ROM) exercises have shown EIH effects. Active stretching exercises have illustrated contradictory effects. Isometric and ROM exercises exerted hypoalgesia at local and remote sites. A larger EIH effect following submaximal aerobic exercises was exerted at the remote testing site compared with the local site.
Publisher: American Physical Society (APS)
Date: 13-08-2020
Publisher: Elsevier BV
Date: 07-2019
Publisher: Springer Science and Business Media LLC
Date: 09-2020
Abstract: Inclusive and differential cross-sections for the production of top quarks in association with a photon are measured with proton-proton collision data corresponding to an integrated luminosity of 139 fb − 1 . The data were collected by the ATLAS detector at the LHC during Run 2 between 2015 and 2018 at a centre-of-mass energy of 13 TeV. The measurements are performed in a fiducial volume defined at parton level. Events with exactly one photon, one electron and one muon of opposite sign, and at least two jets, of which at least one is b -tagged, are selected. The fiducial cross-section is measured to be $$ {39.6}_{-2.3}^{+2.7} $$ 39.6 − 2.3 + 2.7 fb. Differential cross-sections as functions of several observables are compared with state-of-the-art Monte Carlo simulations and next-to-leading-order theoretical calculations. These include cross-sections as functions of photon kinematic variables, angular variables related to the photon and the leptons, and angular separations between the two leptons in the event. All measurements are in agreement with the predictions from the Standard Model.
Publisher: IOP Publishing
Date: 02-10-2020
Publisher: American Physical Society (APS)
Date: 04-06-2020
Publisher: Elsevier BV
Date: 07-2018
DOI: 10.1016/J.APMR.2017.07.019
Abstract: To assess the clinical benefits of joint mobilization for ankle sprains. MEDLINE, MEDLINE In-Process, Embase, AMED, PsycINFO, CINAHL, Cochrane Library, PEDro, Scopus, SPORTDiscus, and Dissertations and Theses were searched from inception to June 2017. Studies investigating humans with grade I or II lateral or medial sprains of the ankle in any pathologic state from acute to chronic, who had been treated with joint mobilization were considered for inclusion. Any conservative intervention was considered as a comparator. Commonly reported clinical outcomes were considered such as ankle range of movement, pain, and function. After screening of 1530 abstracts, 56 studies were selected for full-text screening, and 23 were eligible for inclusion. Eleven studies on chronic sprains reported sufficient data for meta-analysis. Data were extracted using the participants, interventions, comparison, outcomes, and study design approach. Clinically relevant outcomes (dorsiflexion range, proprioception, balance, function, pain threshold, pain intensity) were assessed at immediate, short-term, and long-term follow-up points. Methodological quality was assessed independently by 2 reviewers, and most studies were found to be of moderate quality, with no studies rated as poor. Meta-analysis revealed significant immediate benefits of joint mobilization compared with comparators on improving posteromedial dynamic balance (P=.0004), but not for improving dorsiflexion range (P=.16), static balance (P=.96), or pain intensity (P=.45). Joint mobilization was beneficial in the short-term for improving weight-bearing dorsiflexion range (P=.003) compared with a control. Joint mobilization appears to be beneficial for improving dynamic balance immediately after application, and dorsiflexion range in the short-term. Long-term benefits have not been adequately investigated.
Publisher: American Physical Society (APS)
Date: 14-08-2020
Publisher: Springer Science and Business Media LLC
Date: 13-02-2019
Publisher: SAGE Publications
Date: 15-04-2020
Abstract: Objective. This study aims to describe the clinical features in terms of pain perception, ankle range of motion, and foot volume in participants with recurrent ankle sprains compared with first-time sprains. Methods. In iduals with grade I and II ankle sprains were referred to physiotherapy care for further rehabilitation by their general practitioner. Primary outcome measures were range of movement, pain, and foot volume. Recurrences were described according to engagement in sport. Results. A total of 115 participants were recruited (age = 22.2 ± 6.9 years female, 84). Neither pain level (P = .822), nor range of motion (dorsiflexion P = .452 plantar flexion P = .436 inversion P = .383 eversion P = .657), nor foot volume (P = .654) were significantly different between the groups: in iduals with first-time sprain or with recurrences. Conclusion. Pain and high existence of other lower-limb injuries were reported disregarding the presence of a recurrence. Clinically, it is difficult to differentiate recurrent sprain from a first-time ankle sprain by means of foot volume, range of movement, or pain intensity.
Publisher: Springer Science and Business Media LLC
Date: 08-2020
Abstract: The combination of measurements of the W boson polarization in top quark decays performed by the ATLAS and CMS collaborations is presented. The measurements are based on proton-proton collision data produced at the LHC at a centre-of-mass energy of 8 TeV, and corresponding to an integrated luminosity of about 20 fb − 1 for each experiment. The measurements used events containing one lepton and having different jet multiplicities in the final state. The results are quoted as fractions of W bosons with longitudinal ( F 0 ), left-handed ( F L ), or right-handed ( F R ) polarizations. The resulting combined measurements of the polarization fractions are F 0 = 0 . 693 ± 0 . 014 and F L = 0 . 315 ± 0 . 011. The fraction F R is calculated from the unitarity constraint to be F R = − 0 . 008 ± 0 . 007. These results are in agreement with the standard model predictions at next-to-next-to-leading order in perturbative quantum chromodynamics and represent an improvement in precision of 25 (29)% for F 0 ( F L ) with respect to the most precise single measurement. A limit on anomalous right-handed vector ( V R ), and left- and right-handed tensor ( g L , g R ) tWb couplings is set while fixing all others to their standard model values. The allowed regions are [ − 0 . 11 , 0 . 16] for V R , [ − 0 . 08 , 0 . 05] for g L , and [ − 0 . 04 , 0 . 02] for g R , at 95% confidence level. Limits on the corresponding Wilson coefficients are also derived.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 07-09-2022
DOI: 10.1097/JOM.0000000000002698
Abstract: To understand the flexible work practices during the COVID-19 pandemic and their impact on work-related musculoskeletal disorders (MSDs) and depression in frequent computer users. An e-survey determined the extent of workplace changes and MSD, and the relationships between them using descriptive-statistics and chi-squared tests. Of 700 who commenced the survey, 511 were analyzed. Since the pandemic commenced, 80% of respondents reported they were working more from home and 89% reported some musculoskeletal pain. Compared with prepandemic, more people worked in nonergonomic environments, computer configurations and body postures. Work location was associated with upper back pain ( P = 0.011) body posture with headache ( P = 0.027) and low back pain ( P = 0.003). Nonergonomic work environments of frequent computer users during COVID-19 are related to having upper back pain, whereas nonergonomic postures are related to having headache and low back pain.
Publisher: Elsevier BV
Date: 08-2020
Publisher: MDPI AG
Date: 20-01-2022
DOI: 10.3390/HEALTHCARE10020203
Abstract: The impact of COVID-19 virus infection during pregnancy is still unclear. This systematic review and meta-analysis aimed to quantitatively pool the evidence on impact of COVID-19 infection on perinatal outcomes. Databases of Medline, Embase, and Cochrane library were searched using the keywords related to COVID-19 and perinatal outcomes from December 2019 to 30 June 2021. Observational studies comparing the perinatal outcomes of COVID-19 infection in pregnancy with a non-infected comparator were included. The screening process and quality assessment of the included studies were performed independently by two reviewers. Meta-analyses were used to pool the comparative dichotomous data on perinatal outcomes. The database search yielded 4049 results, 1254 of which were duplicates. We included a total of 21 observational studies that assessed the adverse perinatal outcomes with COVID-19 infection. The odds of maternal death (pooled OR: 7.05 [2.41−20.65]), preecl sia (pooled OR: 1.39 [1.29−1.50]), cesarean delivery (pooled OR: 1.67 [1.29−2.15]), fetal distress (pooled OR: 1.66 [1.35−2.05]), preterm birth (pooled OR: 1.86 [1.34−2.58]), low birth weight (pooled OR: 1.69 [1.35−2.11]), stillbirth (pooled OR: 1.46 [1.16−1.85]), 5th minute Apgar score of less than 7 (pooled OR: 1.44 [1.11−1.86]) and admissions to neonatal intensive care unit (pooled OR: 2.12 [1.36−3.32]) were higher among COVID-19 infected pregnant women compared to non-infected pregnant women.
Publisher: OMICS Publishing Group
Date: 2016
Publisher: Springer Science and Business Media LLC
Date: 11-2020
Abstract: In this paper, a new technique for reconstructing and identifying hadronically decaying τ + τ − pairs with a large Lorentz boost, referred to as the di- τ tagger, is developed and used for the first time in the ATLAS experiment at the Large Hadron Collider. A benchmark di- τ tagging selection is employed in the search for resonant Higgs boson pair production, where one Higgs boson decays into a boosted $$ b\\overline{b} $$ b b ¯ pair and the other into a boosted τ + τ − pair, with two hadronically decaying τ -leptons in the final state. Using 139 fb − 1 of proton-proton collision data recorded at a centre-of-mass energy of 13 TeV, the efficiency of the di- τ tagger is determined and the background with quark- or gluon-initiated jets misidentified as di- τ objects is estimated. The search for a heavy, narrow, scalar resonance produced via gluon-gluon fusion and decaying into two Higgs bosons is carried out in the mass range 1–3 TeV using the same dataset. No deviations from the Standard Model predictions are observed, and 95% confidence-level exclusion limits are set on this model.
Publisher: Elsevier BV
Date: 06-2020
Publisher: Elsevier BV
Date: 02-2022
DOI: 10.1016/J.JMPT.2022.04.001
Abstract: The purpose of this study was to determine the feasibility of using detuned laser as a placebo intervention in manual therapy research. We performed a secondary data analysis of a randomized controlled trial. In our analysis, 30 participants with chronic ankle instability (manual therapy group: n = 13, age = 33.1 ± 8.1 years, female participants = 50% detuned laser group: n = 17, age = 31.9 ± 11.8 years, female participants = 72%) were asked to indicate which intervention (manual therapy [active] or detuned laser [placebo]), they thought they had received and to give a confidence rating on their response regarding the received intervention at the conclusion of the course of intervention. Independent t tests were used to compare the groups. Participants in both groups were asked the following open-ended question: "What did you think of the intervention?". There were 52.9% participants in the detuned laser group and 53.8% participants in the manual therapy group who perceived that they had received the active intervention. The confidence ratings about their perceptions (6.7 ± 2.0, detuned laser group 6.3 ± 2.4, manual therapy group) (P = .66) and the self-reported recovery ratings (1.9 ± 1.5 and 1.8 ± 1.2, respectively) (P = .77) were similar. Participants in this study confidently perceived that detuned laser was an active intervention. They positively rated their recovery following the course of the placebo intervention and perceived that detuned laser was effective in treating their condition. Therefore, it is feasible for detuned laser to be used as a placebo for manual therapy trials.
Publisher: Elsevier BV
Date: 11-2019
Publisher: Lambert Academic Publishing, Germany
Date: 2014
Publisher: JMIR Publications Inc.
Date: 22-01-2023
Abstract: ral anticoagulation is the cornerstone treatment of several diseases. Its management is often challenging, and different telemedicine strategies have been implemented to support it. he aim of the study is to systematically review the evidence on the impact of telemedicine-based oral anticoagulation management compared to usual care on thromboembolic and bleeding events. andomized controlled trials were searched in 5 databases from inception to September 2021. Two independent reviewers performed study selection and data extraction. Total thromboembolic events, major bleeding, mortality, and time in therapeutic range were assessed. Results were pooled using random effect models. n total, 25 randomized controlled trials were included (n=25,746 patients) and classified as moderate to high risk of bias by the Cochrane tool. Telemedicine resulted in lower rates of thromboembolic events, though not statistically significant (n=13 studies, relative risk [RR] 0.75, 95% CI 0.53-1.07 i I /i sup /sup =42%), comparable rates of major bleeding (n=11 studies, RR 0.94, 95% CI 0.82-1.07 i I /i sup /sup =0%) and mortality (n=12 studies, RR 0.96, 95% CI 0.78-1.20 i I /i sup /sup =11%), and an improved time in therapeutic range (n=16 studies, mean difference 3.38, 95% CI 1.12-5.65 i I /i sup /sup =90%). In the subgroup of the multitasking intervention, telemedicine resulted in an important reduction of thromboembolic events (RR 0.20, 95% CI 0.08-0.48). elemedicine-based oral anticoagulation management resulted in similar rates of major bleeding and mortality, a trend for fewer thromboembolic events, and better anticoagulation quality compared to standard care. Given the potential benefits of telemedicine-based care, such as greater access to remote populations or people with ambulatory restrictions, these findings may encourage further implementation of eHealth strategies for anticoagulation management, particularly as part of multifaceted interventions for integrated care of chronic diseases. Meanwhile, researchers should develop higher-quality evidence focusing on hard clinical outcomes, cost-effectiveness, and quality of life. ROSPERO International Prospective Register of Systematic Reviews CRD42020159208 www.crd.york.ac.uk rospero/display_record.php?RecordID=159208
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 28-02-2023
Publisher: JMIR Publications Inc.
Date: 10-07-2023
DOI: 10.2196/45922
Abstract: Oral anticoagulation is the cornerstone treatment of several diseases. Its management is often challenging, and different telemedicine strategies have been implemented to support it. The aim of the study is to systematically review the evidence on the impact of telemedicine-based oral anticoagulation management compared to usual care on thromboembolic and bleeding events. Randomized controlled trials were searched in 5 databases from inception to September 2021. Two independent reviewers performed study selection and data extraction. Total thromboembolic events, major bleeding, mortality, and time in therapeutic range were assessed. Results were pooled using random effect models. In total, 25 randomized controlled trials were included (n=25,746 patients) and classified as moderate to high risk of bias by the Cochrane tool. Telemedicine resulted in lower rates of thromboembolic events, though not statistically significant (n=13 studies, relative risk [RR] 0.75, 95% CI 0.53-1.07 I2=42%), comparable rates of major bleeding (n=11 studies, RR 0.94, 95% CI 0.82-1.07 I2=0%) and mortality (n=12 studies, RR 0.96, 95% CI 0.78-1.20 I2=11%), and an improved time in therapeutic range (n=16 studies, mean difference 3.38, 95% CI 1.12-5.65 I2=90%). In the subgroup of the multitasking intervention, telemedicine resulted in an important reduction of thromboembolic events (RR 0.20, 95% CI 0.08-0.48). Telemedicine-based oral anticoagulation management resulted in similar rates of major bleeding and mortality, a trend for fewer thromboembolic events, and better anticoagulation quality compared to standard care. Given the potential benefits of telemedicine-based care, such as greater access to remote populations or people with ambulatory restrictions, these findings may encourage further implementation of eHealth strategies for anticoagulation management, particularly as part of multifaceted interventions for integrated care of chronic diseases. Meanwhile, researchers should develop higher-quality evidence focusing on hard clinical outcomes, cost-effectiveness, and quality of life. PROSPERO International Prospective Register of Systematic Reviews CRD42020159208 www.crd.york.ac.uk rospero/display_record.php?RecordID=159208
Publisher: Springer Science and Business Media LLC
Date: 11-2020
Abstract: A search for new physics with non-resonant signals in dielectron and dimuon final states in the mass range above 2 TeV is presented. This is the first search for non-resonant signals in dilepton final states at the LHC to use a background estimate from the data. The data, corresponding to an integrated luminosity of 139 fb − 1 , were recorded by the ATLAS experiment in proton-proton collisions at a center-of-mass energy of $$ \\sqrt{s} $$ s = 13 TeV during Run 2 of the Large Hadron Collider. The benchmark signal signature is a two-quark and two-lepton contact interaction, which would enhance the dilepton event rate at the TeV mass scale. To model the contribution from background processes a functional form is fit to the dilepton invariant-mass spectra in data in a mass region below the region of interest. It is then extrapolated to a high-mass signal region to obtain the expected background there. No significant deviation from the expected background is observed in the data. Upper limits at 95% CL on the number of events and the visible cross-section times branching fraction for processes involving new physics are provided. Observed (expected) 95% CL lower limits on the contact interaction energy scale reach 35.8 (37.6) TeV.
Publisher: MDPI AG
Date: 17-04-2023
Abstract: Interprofessional learning (IPL), where nursing students learn how to work with multiple health professionals in their future practice to deliver the highest quality of care, has become an essential feature of undergraduate nursing programs. Intraprofessional learning (IaPL) is where in iduals of two or more disciplines within the same profession collaborate however, there is a dearth of literature investigating its effects in nursing education. The aim of this study is to investigate the impact of IaPL on the development of nursing students’ knowledge, skills, and attitudes for collaborative practice. The study will utilize a mixed methods approach with surveys conducted at six time points across two years of two nursing programs and focus groups at the end of the program. Participants will be recruited from the Diploma and Bachelor of Nursing programs at an Australian Training and Further Education institute. Four specific IaPL educational experiences incorporating simulation will be developed on aged care, mental health, complex care and acute care. The study will provide nursing students with multiple opportunities to develop the necessary capabilities for collaborative practice. It will longitudinally evaluate nursing students’ attitudes towards IaPL and examine whether IaPL motivates Diploma of Nursing students to pathway into a Bachelor of Nursing degree. The study will also investigate awareness amongst nursing students of the scope of practice, roles and responsibilities of the nursing team.
Publisher: Copernicus GmbH
Date: 24-07-2020
Publisher: Springer Science and Business Media LLC
Date: 07-2020
Abstract: Single top-quark production in association with a Z boson, where the Z boson decays to a pair of charged leptons, is measured in the trilepton channel. The proton-proton collision data collected by the ATLAS experiment from 2015 to 2018 at a centre-of-mass energy of 13 TeV are used, corresponding to an integrated luminosity of 139 fb − 1 . Events containing three isolated charged leptons (electrons or muons) and two or three jets, one of which is identified as containing a b -hadron, are selected. The main backgrounds are from $$ t\\overline{t}Z $$ t t ¯ Z and diboson production. Neural networks are used to improve the background rejection and extract the signal. The measured cross-section for t ℓ + ℓ − q production, including non-resonant dilepton pairs with $$ {m}_{{\\mathrm{\\ell}}^{+}{\\mathrm{\\ell}}^{-}} $$ m ℓ + ℓ − 30 GeV, is 97 ± 13 (stat.) ± 7 (syst.) fb, consistent with the Standard Model prediction.
Publisher: Public Library of Science (PLoS)
Date: 13-06-2019
Publisher: Public Library of Science (PLoS)
Date: 17-09-2020
Publisher: Springer Science and Business Media LLC
Date: 25-05-2017
Publisher: Springer Science and Business Media LLC
Date: 07-2020
Abstract: This paper presents a measurement of the production cross-section of a Z boson in association with b -jets, in proton-proton collisions at $$ \sqrt{s} $$ s = 13 TeV with the ATLAS experiment at the Large Hadron Collider using data corresponding to an integrated luminosity of 35.6 fb − 1 . Inclusive and differential cross-sections are measured for events containing a Z boson decaying into electrons or muons and produced in association with at least one or at least two b -jets with transverse momentum p T 20 GeV and rapidity |y| 2 . 5. Predictions from several Monte Carlo generators based on leading-order (LO) or next-to-leading-order (NLO) matrix elements interfaced with a parton-shower simulation and testing different flavour schemes for the choice of initial-state partons are compared with measured cross-sections. The 5-flavour number scheme predictions at NLO accuracy agree better with data than 4-flavour number scheme ones. The 4-flavour number scheme predictions underestimate data in events with at least one b-jet.
Publisher: Copernicus GmbH
Date: 14-01-2021
Abstract: Abstract. Hydroxymethanesulfonate (HMS) has recently been identified as an abundant organosulfur compound in aerosols during winter haze episodes in northern China. It has also been detected in other regions although the concentrations are low. Because of the sparse field measurements, the global significance of HMS and its spatial and seasonal patterns remain unclear. Here, we modify and add to the implementation of HMS chemistry in the GEOS-Chem chemical transport model and conduct multiple global simulations. The model accounts for cloud entrainment and gas–aqueous mass transfer within the rate expressions for heterogeneous sulfur chemistry. Our simulations can generally reproduce quantitative HMS observations from Beijing and show that East Asia has the highest HMS concentration, followed by Europe and North America. The simulated HMS shows a seasonal pattern with higher values in the colder period. Photochemical oxidizing capacity affects the competition of formaldehyde with oxidants (such as ozone and hydrogen peroxide) for sulfur dioxide and is a key factor influencing the seasonality of HMS. The highest average HMS concentration (1–3 µg m−3) and HMS ∕ sulfate molar ratio (0.1–0.2) are found in northern China in winter. The simulations suggest that aqueous clouds act as the major medium for HMS chemistry while aerosol liquid water may play a role if its rate constant for HMS formation is greatly enhanced compared to cloud water.
Publisher: Elsevier BV
Date: 11-2022
Publisher: Elsevier BV
Date: 10-2020
Publisher: Springer Science and Business Media LLC
Date: 10-2020
Abstract: Results of a search for new particles decaying into eight or more jets and moderate missing transverse momentum are presented. The analysis uses 139 fb − 1 of proton-proton collision data at $$ \\sqrt{s} $$ s = 13 TeV collected by the ATLAS experiment at the Large Hadron Collider between 2015 and 2018. The selection rejects events containing isolated electrons or muons, and makes requirements according to the number of b -tagged jets and the scalar sum of masses of large-radius jets. The search extends previous analyses both in using a larger dataset and by employing improved jet and missing transverse momentum reconstruction methods which more cleanly separate signal from background processes. No evidence for physics beyond the Standard Model is found. The results are interpreted in the context of supersymmetry-inspired simplified models, significantly extending the limits on the gluino mass in those models. In particular, limits on the gluino mass are set at 2 TeV when the lightest neutralino is nearly massless in a model assuming a two-step cascade decay via the lightest chargino and second-lightest neutralino.
Publisher: Springer Science and Business Media LLC
Date: 10-2020
Abstract: This paper presents a search for new heavy particles decaying into a pair of top quarks using 139 fb − 1 of proton-proton collision data recorded at a centre-of-mass energy of $$ \\sqrt{s} $$ s = 13 TeV with the ATLAS detector at the Large Hadron Collider. The search is performed using events consistent with pair production of high-transverse-momentum top quarks and their subsequent decays into the fully hadronic final states. The analysis is optimized for resonances decaying into a $$ t\\overline{t} $$ t t ¯ pair with mass above 1.4 TeV, exploiting a dedicated multivariate technique with jet substructure to identify hadronically decaying top quarks using large-radius jets and evaluating the background expectation from data. No significant deviation from the background prediction is observed. Limits are set on the production cross-section times branching fraction for the new Z ′ boson in a topcolor-assisted-technicolor model. The Z ′ boson masses below 3.9 and 4.7 TeV are excluded at 95% confidence level for the decay widths of 1% and 3%, respectively.
Publisher: EDP Sciences
Date: 04-2021
DOI: 10.1051/0004-6361/202038488
Abstract: Aims. The giant H II region 30 Doradus (30 Dor) located in the eastern part of the Large Magellanic Cloud is one of the most active star-forming regions in the Local Group. Studies of H I data have revealed two large gas structures which must have collided with each other in the region around 30 Dor. In X-rays there is extended emission (~1 kpc) south of 30 Dor called the X-ray spur, which appears to be anticorrelated with the H I gas. We study the properties of the hot interstellar medium (ISM) in the X-ray spur and investigate its origin including related interactions in the ISM. Methods. We analyzed new and archival XMM-Newton data of the X-ray spur and its surroundings to determine the properties of the hot diffuse plasma. We created detailed plasma property maps by utilizing the Voronoi tessellation algorithm. We also studied H I and CO data, as well as optical line emission data of H α and [S II ], and compared them to the results of the X-ray spectral analysis. Results. We find evidence of two hot plasma components with temperatures of kT 1 ~ 0.2 keV and kT 2 ~ 0.5−0.9 keV, with the hotter component being much more pronounced near 30 Dor and the X-ray spur. In 30 Dor, the plasma has most likely been heated by massive stellar winds and supernova remnants. In the X-ray spur, we find no evidence of heating by stars. Instead, the X-ray spur must have been compressed and heated by the collision of the H I gas.
Publisher: Informa UK Limited
Date: 13-11-0021
Publisher: SAGE Publications
Date: 2021
DOI: 10.1177/23337214211057392
Abstract: Whilst people of all ages are affected in some way by COVID-19 virus, older people are at a high mortality risk. This study aimed to systematically review the numerous factors associated with mortality among COVID-19 infected older people. PubMed and Science Direct were searched from inception to the April 15, 2021. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement and Joanna Briggs Institute critical appraisal tool to assess the methodological quality of the included studies. Of the 4957 studies identified, 20 were included in the qualitative analysis, while 10 were included in the quantitative analysis. Male sex (OR = 2.22, 95% CI = 1.23–3.99), age (over 75 years old) (OR = 3.36, 95% CI = 2.30–4.90), Dementia (OR = 3.69, 95% CI = 1.99–6.83) and Dyspnoea (OR = 3.16, 95% CI = 2.61–3.82), were found to be significantly associated with mortality. There is no significant association between Diabetes, or Hypertension. Older age, male gender, dyspnoea and dementia were associated with a greater risk of death of older people from COVID-19 infection. These findings may help health care professionals to identify high-risk groups, facilitate appropriate remedial measures, and control mortality among older people.
Publisher: Springer Science and Business Media LLC
Date: 08-2020
DOI: 10.1140/EPJC/S10052-020-8181-6
Abstract: A measurement of observables sensitive to spin correlations in $$t\\bar{t}$$ t t ¯ production is presented, using 36.1 $$\\hbox {fb}^{-1}$$ fb - 1 of pp collision data at $$\\sqrt{s} = 13$$ s = 13 TeV recorded with the ATLAS detector at the Large Hadron Collider. Differential cross-sections are measured in events with exactly one electron and one muon with opposite-sign electric charge as a function of the azimuthal opening angle and the absolute difference in pseudorapidity between the electron and muon candidates in the laboratory frame. The azimuthal opening angle is also measured as a function of the invariant mass of the $$t\\bar{t}$$ t t ¯ system. The measured differential cross-sections are compared to predictions by several NLO Monte Carlo generators and fixed-order calculations. The observed degree of spin correlation is somewhat higher than predicted by the generators used. The data are consistent with the prediction of one of the fixed-order calculations at NLO, but agree less well with higher-order predictions. Using these leptonic observables, a search is performed for pair production of supersymmetric top squarks decaying into Standard Model top quarks and light neutralinos. Top squark masses between 170 and 230 GeV are largely excluded at the 95% confidence level for kinematically allowed values of the neutralino mass.
Publisher: Elsevier BV
Date: 08-2023
Publisher: Elsevier BV
Date: 2021
Publisher: Springer Science and Business Media LLC
Date: 06-01-2021
DOI: 10.1186/S40798-020-00290-7
Abstract: Netball is estimated to be played by more than 20 million people worldwide, but there is evidence of high injury incidence. A thorough understanding of the types and rates of netball injuries is essential for effective injury management and prevention strategies to be developed and implemented. This systematic review summarises the published findings with respect to injury types, participant characteristics and any identified risk factors for netball injuries. A librarian-assisted computer search of seven scientific databases was conducted for studies reporting on netball injuries. Inclusion criteria were studies published in English, in peer-reviewed journals, which reported data on injuries and variables (e.g. age and competition level) that have been proposed as possibly associated with netball injury risk. Forty-six studies (43.5% prospective, 37% hospital/insurance records, 19.5% retrospective) from 45 articles were included after screening. The majority of studies (74%) were conducted in Australia or New Zealand. There was little consistency in the definition of ‘injury’. Elite or sub-elite level players were included in 69% of studies where the level of competition was reported. The duration of injury surveillance was generally related to the format of competition from which data were collected. Self-report questionnaires were used in 48% of studies and only 26% of studies used qualified health professionals to collect data courtside. Injuries to the ankle and knee were the most common (in 19 studies) although the incidence varied considerably across the studies (ankle 13–84% and knee 8–50% of injuries). Prevention of ankle and knee injuries should be a priority. Children sustained more upper limb injuries (e.g. fractures) compared with adults who sustained more lower limb injuries (e.g. ankle and knee sprains/strains). A large number of potential risk factors for injury in netball have been investigated in small numbers of studies. The main circumstances of injury are landings, collisions and falls. Further studies should be directed towards recreational netball, reporting on injury incidence in players by age and utilising high-quality, standardised methods and criteria. Specific injury diagnosis and a better understanding of the circumstances and mechanisms of injury would provide more meaningful data for developing prevention strategies.
Publisher: Elsevier BV
Date: 2017
Publisher: Springer Science and Business Media LLC
Date: 11-2020
DOI: 10.1140/EPJC/S10052-020-08469-8
Abstract: This paper presents a search for direct top squark pair production in events with missing transverse momentum plus either a pair of jets consistent with Standard Model Higgs boson decay into b -quarks or a same-flavour opposite-sign dilepton pair with an invariant mass consistent with a Z boson. The analysis is performed using the proton–proton collision data at $$\\sqrt{s}=13$$ s = 13 TeV collected with the ATLAS detector during the LHC Run-2, corresponding to an integrated luminosity of 139 fb $$^{-1}$$ - 1 . No excess is observed in the data above the Standard Model predictions. The results are interpreted in simplified models featuring direct production of pairs of either the lighter top squark ( $$\\tilde{t}_1$$ t ~ 1 ) or the heavier top squark ( $$\\tilde{t}_2$$ t ~ 2 ), excluding at 95% confidence level $$\\tilde{t}_1$$ t ~ 1 and $$\\tilde{t}_2$$ t ~ 2 masses up to about 1220 and 875 GeV, respectively.
Publisher: Copernicus GmbH
Date: 24-07-2020
DOI: 10.5194/ACP-2020-643
Abstract: Abstract. Hydroxymethanesulfonate (HMS) has recently been identified as an abundant organosulfur compound in aerosols during winter haze episodes in northern China. It has also been detected in other regions, although the concentrations are low. Because of the sparse field measurements, the global significance of HMS and its spatial and seasonal patterns remain unclear. Here, we implement HMS chemistry into the GEOS-Chem chemical transport model and conduct multiple global simulations. The developed model accounts for cloud entrainment and gas–aqueous mass transfer within the rate expressions for heterogeneous sulfur chemistry. Our simulations can generally reproduce the available HMS observations, and show that East Asia has the highest HMS concentration, followed by Europe and North America. The simulated HMS shows a seasonal pattern with higher values in the colder period. Photochemical oxidizing capacity affects the competition of formaldehyde with oxidants (such as ozone and hydrogen peroxide) for sulfur dioxide and is a key factor influencing the seasonality of HMS. The highest average HMS concentration (1–3 μg m−3) and HMS/sulfate molar ratio (0.1–0.2) are found in northern China winter. The simulations suggest that aqueous clouds act as the major medium for HMS chemistry while aerosol liquid water may play a role if its rate constant for HMS formation is greatly enhanced compared to cloud water.
Publisher: IOP Publishing
Date: 10-11-2020
Publisher: SAGE Publications
Date: 22-06-2016
Abstract: Objective. This study was conducted to determine the most effective thermal modality heat or contrast therapy—in reducing pain, reducing swelling, and increasing range of movement (ROM) of the grade I and II lateral ankle sprain in the prechronic stage of the subacute phase. Design. Randomized control trail. Methods. One hundred and fifteen participants of both genders who were diagnosed as having grade I or II lateral ankle sprain were randomly assigned to the study on the fifth day of injury. Pain, volume, and ROM were recorded before and after treatment continuously for 3 days. Results. Effects were evaluated as “Immediately after application” and “3 days after continuous application.” Immediately after application, there was no difference between the 2 modalities on ankle ROM heat reduced pain over contrast therapy, and both modalities increased swelling. When considering the effects after continuous application for 3 days, no difference was found between the 2 modalities on ROM and the reduction of pain. Contrast therapy reduced swelling while heat caused increased swelling even after 3 days. Conclusion. The use of different thermal modalities during the transition from the acute to chronic phase of injury can be suggested as effective treatment options according to the objectives of injury management: pain reduction, improve ROM, and swelling management. Levels of Evidence: Therapeutic, Level II: Randomized clinical trial
Location: United States of America
Location: Australia
Location: Sri Lanka
Location: Australia
No related grants have been discovered for Ishanka Weerasekara.