ORCID Profile
0000-0003-3781-0464
Current Organisations
University of Birmingham
,
University of Southampton
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Publisher: American Chemical Society (ACS)
Date: 28-06-2022
DOI: 10.1021/JACS.2C02029
Abstract: Catenanes composed of two achiral rings that are oriented (C
Publisher: Springer Science and Business Media LLC
Date: 27-06-2022
Publisher: Royal Society of Chemistry (RSC)
Date: 2009
DOI: 10.1039/B804243H
Abstract: Active metal template synthesis is a powerful new strategy for the construction of rotaxanes, catenanes and other mechanically interlocked molecular structures. The key feature is that the metal plays a dual role during the assembly of the interlocked architecture, acting as both a template for entwining or threading the components and as a catalyst for capturing the interlocked final product by covalent bond formation. Unlike traditional "passive" metal template methods to rotaxanes and catenanes, permanent recognition motifs are not required on each of the components to be interlocked (i.e., the assembly can be traceless) and the template can often be used in sub-stoichiometric quantities. Since its inception in 2006, a rapidly growing number of different metal-catalysed reactions have proven suitable for the active metal template synthesis of both rotaxanes and catenanes, including the copper(i)-catalysed terminal alkyne-azide cycloaddition (the CuAAC "click" reaction), palladium- and copper-catalysed alkyne homocouplings and heterocouplings, and palladium-catalysed oxidative Heck couplings and Michael additions. In addition to simple rotaxanes and catenanes, the synthetic strategy has been used to construct switchable molecular shuttles with weak intercomponent interactions (a requirement for fast shuttling) and to provide insight into the mechanisms of transition metal-catalysed reactions. In this tutorial review we highlight the utility and potential of the early ex les of the active metal template strategy in mechanically interlocked molecule synthesis.
Publisher: Wiley
Date: 05-03-2018
Abstract: We report a rotaxane based on a simple urea motif that binds Cl − selectively as a separated ion pair with H + and reports the anion binding event through a fluorescence switch‐on response. The host selectively binds Cl − over more basic anions, which deprotonate the framework, and less basic anions, which bind more weakly. The mechanical bond also imparts size selectivity to the ditopic host.
Publisher: Royal Society of Chemistry (RSC)
Date: 2010
DOI: 10.1039/C0SC00279H
Publisher: Wiley
Date: 27-08-2008
Publisher: Wiley
Date: 05-03-2018
Publisher: Wiley
Date: 14-04-2008
Publisher: Royal Society of Chemistry (RSC)
Date: 2012
DOI: 10.1039/C2CS90105F
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Stephen Goldup.