ORCID Profile
0000-0002-5010-8744
Current Organisation
Deakin University
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Publisher: Wiley
Date: 03-2018
Abstract: The capability to study the dynamic formation of plasmonic molecular junction is of fundamental importance, and it will provide new insights into molecular electronics lasmonics, single-entity electrochemistry, and nanooptoelectronics. Here, a facile method to form plasmonic molecular junctions is reported by utilizing single gold nanoparticle (NP) collision events at a highly curved gold nanoelectrode modified with a self-assembled monolayer. By using time-resolved electrochemical current measurement and surface-enhanced Raman scattering spectroscopy, the current changes and the evolution of interfacial chemical bonding are successfully observed in the newly formed molecular tunnel junctions during and after the gold NP "hit-n-stay" and "hit-n-run" collision events. The results lead to an in-depth understanding of the single NP motion and the associated molecular level changes during the formation of the plasmonic molecular junctions in a single NP collision event. This method also provides a new platform to study molecular changes at the single molecule level during electron transport in a dynamic molecular tunnel junction.
Publisher: Royal Society of Chemistry (RSC)
Date: 2012
DOI: 10.1039/C2CC18069C
Abstract: In this communication we describe a new approach to the fabrication of fluorescent silver olymer nanohybrids with thermo-switchable metal enhanced fluorescence (MEF). By manipulating a soft polymer spacer between the silver nanoparticles and the fluorophores a tunable MEF was achieved.
Publisher: Springer Science and Business Media LLC
Date: 02-04-2016
Publisher: Elsevier BV
Date: 08-2016
Publisher: Elsevier BV
Date: 10-2021
Publisher: Elsevier BV
Date: 2015
Publisher: Elsevier BV
Date: 07-2015
DOI: 10.1016/J.TALANTA.2015.02.010
Abstract: In this study, electron transfer behavior of the graphene nanosheets attachment on glassy carbon electrode (GCE) via direct electrochemical reduction of graphene oxide (GO) is investigated for the first time. The graphene modified electrode was achieved by simply dipping the GCE in GO suspension, followed by cyclic voltammetric scanning in the potential window from 0V to -1.5V. Tris(2,2'-bipyridyl)ruthenium(II) [Ru(bpy)3(2+)] was immobilized on the graphene modified electrode and used as the redox probe to evaluate the electron transfer behavior. The electron transfer rate constant (Ks) was calculated to be 61.9±5.8s(-1), which is much faster than that of tiled graphene modified GCE (7.1±0.6s(-1)). The enhanced electron transfer property observed with the GCE modified by reductively deposited graphene is probably due to its standing configuration, which is beneficial to the electron transfer comparing with the tiled one. Because the abundant oxygen-containing groups are mainly located at the edges of GO, which should be much easier for the reduction to start from, the reduced GO should tend to stand on the electrode surface as evidenced by scanning electron microscopy analysis. In addition, due to the favored electron transfer and standing configuration, the Ru(bpy)3(2+) electrochemiluminescence sensor fabricated with standing graphene modified GCE provided much higher and more stable efficiency than that fabricated with tiled graphene.
Publisher: Elsevier BV
Date: 05-2017
Publisher: Wiley
Date: 29-09-2021
Abstract: Periodontal defect regeneration in severe periodontitis relies on the differentiation and proliferation of periodontal ligament cells (PDLCs). Recently, an emerging 2D nanomaterial, MXene (Ti 3 C 2 T x ), has gained more and more attention due to the extensive antibacterial and anticancer activity, while its potential biomedical application on tissue regeneration remains unclear. Through a combination of experimental and multiscale simulation schemes, Ti 3 C 2 T x has exhibited satisfactory biocompatibility and induced distinguish osteogenic differentiation of human PDLCs (hPDLCs), with upregulated osteogenesis‐related genes. Ti 3 C 2 T x manages to activate the Wnt/ β ‐catenin signaling pathway by enhancing the Wnt‐Frizzled complex binding, thus stabilizing HIF‐1 α and altering metabolic reprogramming into glycolysis. In vivo, hPDLCs pretreated by Ti 3 C 2 T x display excellent performance in new bone formation and osteoclast inhibition with enhanced RUNX2, HIF‐1 α , and β ‐catenin in an experimental rat model of periodontal fenestration defects, indicating that this material has high efficiency of periodontal regeneration promotion. It is demonstrated in this work that Ti 3 C 2 T x has highly efficient therapeutic effects in osteogenic differentiation and periodontal defect repairment.
Publisher: Springer Science and Business Media LLC
Date: 20-08-2014
Publisher: Wiley
Date: 20-09-2014
Publisher: Elsevier BV
Date: 2014
Publisher: CSIRO Publishing
Date: 2014
DOI: 10.1071/CH13593
Abstract: Luminescent rare earth complex (REC) nanocomposites, Eu(TTA)3Phen attached onto Ag@SiO2 nanoshells, were fabricated by facile wet chemistry and self-assembly techniques. Transmission electron microscopy, and fourier transform infrared and UV–Vis spectroscopy were used to investigate the step-by-step fabrication. The luminescence of REC was significantly enhanced using a silver core (size: 45 nm) surrounded by a 20-nm thick silica shell. Thicker or thinner silica shells afforded tuning of the metal-enhanced luminescence. The thiophene-TTA-containing REC fluorophore was able to etch the silver core, resulting in hollow silica shells, consequently displaying no luminescence enhancing capabilities. The etching efficiency was proportional to the concentration of Eu(TTA)3Phen, and decreased with increasing shell thickness.
Publisher: American Chemical Society (ACS)
Date: 03-07-2020
Publisher: Elsevier BV
Date: 10-2013
Publisher: Royal Society of Chemistry (RSC)
Date: 2013
DOI: 10.1039/C3AN36929C
Abstract: The fabrication of glucose oxidase (GOx) enzyme electrodes with controlled alternate enzyme and graphene layers is described. GOx was first modified with pyrene functionalities in order to be self-assembled onto a graphene basal plane via non-covalent π-π stacking interaction. Fluorescence spectroscopy analysis revealed that about 5.4 pyrene functional groups were attached to each GOx and the pyrene functionalized GOx retained more than 76% of the biocatalytical activity compared with the native enzyme. Via alternate layer-by-layer self-assembly of graphene and pyrene functionalized GOx, mono- and multi-layered enzyme electrodes with controlled biocatalytical activity can be easily fabricated. The biocatalytical activity of the as-prepared enzyme electrodes increased with increasing graphene and GOx layers and increased insignificantly when the layers reached four. Such multi-layered enzyme electrodes with controlled nanostructure exhibited reliable application in human serum s les analysis with high detection sensitivity, good stability and repeatability. A broad linear detection limit of 0.2 to 40 mM was obtained.
Publisher: American Chemical Society (ACS)
Date: 15-12-2022
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9ME00008A
Abstract: Design and formation of electron transfer pathways across self-assembled monolayers by the hydrophobic attachment of BN-NH 2 and MoS 2 nanosheets.
Publisher: Wiley
Date: 20-04-2020
Publisher: Springer Science and Business Media LLC
Date: 28-07-2022
DOI: 10.1007/S00604-022-05387-2
Abstract: An ultrasensitive luminol electrochemiluminescence (ECL) immunosensor was constructed for the detection of prostate specific antigen (PSA) using glucose oxidase-decorated hemin-graphene oxide-gold nanoflowers ternary nanocomposites as probes. Graphene oxide was first modified with hemin and then with gold nanoflowers through an in situ growth method, which has significantly boosted the catalytic activity of this graphene oxide-based peroxidase mimetics. The biocatalytical activity of this ECL immunosensor was thoroughly investigated to achieve selective recognition of the analyte molecules (PSA) by specific binding between antigens and antibodies. The limit of detection was calculated to be 0.32 pg mL
Publisher: SAGE Publications
Date: 21-07-2022
DOI: 10.1177/10870547221112941
Abstract: Previous studies at child and youth mental health services (CYMHS) suggest that children with ADHD have poorer outcomes compared to those with other diagnoses. This study investigates this in more detail. Children with ADHD were compared to those with ASD and those with emotional disorders, on routinely collected outcomes at CYMHS in Australia ( N = 2,513) and the Netherlands ( N = 844). Where the emotional disorders group reached a similar level of emotional symptoms at the end-of-treatment as the ADHD and ASD groups, the latter two groups still had higher scores on ADHD and ASD symptoms (attention and peer problems). The poorer outcomes were mainly explained by higher severity at baseline. In Australia, an ADHD and/or ASD diagnosis also independently contributed to worse outcomes. Those with neurodevelopmental disorders within both countries had poorer outcomes than those with emotional disorders. Services should aim to optimize treatment to ensure best possible outcomes.
Publisher: Elsevier BV
Date: 11-2022
Publisher: Elsevier BV
Date: 03-2013
Publisher: American Chemical Society (ACS)
Date: 23-01-2014
DOI: 10.1021/JP411979X
Publisher: Ivyspring International Publisher
Date: 2017
DOI: 10.7150/THNO.17252
Publisher: Elsevier BV
Date: 03-2023
Publisher: Elsevier BV
Date: 2016
DOI: 10.1016/J.TALANTA.2015.09.020
Abstract: A uniform graphene nanodots inlaid porous gold electrode was prepared via ion beam sputtering deposition (IBSD) and mild corrosion chemistry. HRTEM, SEM, AFM and XPS analyses revealed the successful fabrication of graphene nanodots inlaid porous gold electrode. The as-prepared porous electrode was used as π-orbital-rich drug loading platform to fabricate an electrochemically controlled drug release system with high performance. π-orbital-rich drugs with amino mioety, like doxorubicin (DOX) and tetracycline (TC), were loaded into the graphene nanodots inlaid porous gold electrode via non-covalent π-π stacking interaction. The amino groups in DOX and TC can be easily protonated at acidic medium to become positively-charged NH3(+), which allow these drug molecules to be desorbed from the porous electrode surface via electrostatic repulsion when positive potential is applied at the electrode. The drug loading and release experiment indicated that this graphene nanodots inlaid porous gold electrode can be used to conveniently and efficiently control the drug release electrochemically. Not only did our work provide a benign method to electrochemically controlled drug release via electrostatic repulsion process, it also enlighten the promising practical applications of micro electrode as a drug carrier for precisely and efficiently controlled drug release via embedding in the body.
Publisher: Wiley
Date: 09-06-2022
Abstract: Wearable electronics demand energy storage devices with high energy density and fast charging‐discharging rates. Although various porous electrodes have been constructed, the effect of pore size on the capacitive performance of 2D nanomaterials has been rarely studied. Herein, flexible MXene foams with significantly different pore structures are fabricated using varying diameter polystyrene (PS) spheres (80, 310, and 570 nm), which shows uniform pores and interconnected pores providing enough active sites and a good electrical connection for electron transfer. Noteworthy, when MXene flakes and templates (310 nm) have a similar size, the foam delivers the highest gravimetric capacitance of 474 ± 12 F g −1 at 2 mV s −1 than others. Additionally, the mass ratio between MXene and PS controls the packing density of foams influencing the inner resistance of foam electrodes. A carbon nanotube is introduced to further improve the electrical conductivity of foams to achieve a capacitance of 462 ± 8 F g −1 at 2 mV s −1 and retains 205 ± 10 F g −1 at 1000 mV s −1 , demonstrating promises in energy storage applications and providing an insightful guidance for designing 2D nanomaterials‐based porous electrodes for supercapacitors.
Publisher: American Scientific Publishers
Date: 08-2013
Publisher: American Chemical Society (ACS)
Date: 24-06-2021
DOI: 10.1021/JACS.1C02426
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D1NR07387G
Abstract: A long shelf time MXene ink was prepared using a mixture of water and ethylene glycol and is a promising candidate for fabricating conductive circuits and paper-based flexible devices.
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C5CC06228D
Abstract: We describe an alternative electrochemical technique to monitor covalent bond formation in real-time using nanoparticle–electrode collisions.
Publisher: Elsevier BV
Date: 06-2019
DOI: 10.1016/J.BIOMATERIALS.2019.03.039
Abstract: The regeneration of lost periodontal apparatus in periodontitis treatment remains a clinical challenge due to the limited regenerative capacity of cementum, periodontal ligament and alveolar bone in periodontitis condition. For periodontal tissue regeneration, it is essential to regulate the inflammatory response and the subsequent differentiation of periodontal cells under the condition due to the infectious nature of the disease. In this study, it was noted that 45 nm gold nanoparticles (AuNPs) could exhibit significant anti-inflammatory effect and improve the periodontal inflammatory microenvironment via regulating inflammatory and regenerative cytokine production and modulating macrophage polarization, subsequently affect the differentiation of human periodontal ligament cells (hPDLCs). With the addition of direct effects of AuNPs on hPDLCs, the periodontal tissue differentiation capacity of hPDLCs in LPS-activated inflammatory macrophage-hPDLCs coculture system was significantly enhanced by the interaction between AuNPs-conditioned macrophage and AuNPs-stimulated hPDLCs. The potential therapeutic application of AuNPs in periodontal tissue regeneration and periodontitis treatment was investigated using both rat fenestration and ligature-induced periodontitis models. It was found that the treatment of 45 AuNPs showed significantly increased newly-formed periodontal attachment, bone and cementum in periodontal defect and less tissue destruction in the progression of periodontitis. This study demonstrated that 45 nm AuNPs could not only directly modulate hPDLCs, but also regulate the early inflammatory response of periodontal tissues via the regulation of macrophage phenotypes, therefore, generate a microenvironment with constraint inflammatory cytokine levels and reparative cytokines such as bone morphogenetic protein-2 (BMP-2), leading to PDLC differentiation, periodontal tissue regeneration and the prevention of periodontitis progression.
No related grants have been discovered for NA KONG.