ARDC Research Link Australia

ORCID Profile
Orcid icon. 0000-0002-2521-2582

Current Organisations
Centro de Reabilitação Funcional Animal – C.R.A.A. , Hospital Veterinário da Arrábida , Centro de Reabilitação e Regeneração Animal de Lisboa – CR2AL , Instituto Politécnico da Lusofonia Escola Superior de Saúde Proteção e Bem-Estar Animal , Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas , Universidade de Lisboa Faculdade de Medicina Veterinária , Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária

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Publications

Publication

Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation

Publisher: MDPI AG

Date: 10-02-2022

DOI: 10.3390/IJERPH19041992

Abstract: Molecular hydrogen (H2) is potentially a novel therapeutic gas for acute post-coronavirus disease 2019 (COVID-19) patients because it has antioxidative, anti-inflammatory, anti-apoptosis, and antifatigue properties. The aim of this study was to determine the effect of 14 days of H2 inhalation on the respiratory and physical fitness status of acute post-COVID-19 patients. This randomized, single-blind, placebo-controlled study included 26 males (44 ± 17 years) and 24 females (38 ± 12 years), who performed a 6-min walking test (6 MWT) and pulmonary function test, specifically forced vital capacity (FVC) and expiratory volume in the first second (FEV1). Symptomatic participants were recruited between 21 and 33 days after a positive polymerase chain reaction test. The experiment consisted of H2 lacebo inhalation, 2 × 60 min/day for 14 days. Results showed that H2 therapy, compared with placebo, significantly increased 6 MWT distance by 64 ± 39 m, FVC by 0.19 ± 0.24 L, and, in FEV1, by 0.11 ± 0.28 L (all p ≤ 0.025). In conclusion, H2 inhalation had beneficial health effects in terms of improved physical and respiratory function in acute post-COVID-19 patients. Therefore, H2 inhalation may represent a safe, effective approach for accelerating early function restoration in post-COVID-19 patients.

Related Organisations

Organisation

Universidade Lusófona

Location: Portugal

Ângela Rocha Martins

Researcher

Related Links

Publications

Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation

Related Organisations

Universidade Lusófona

Universidade De Lisboa

Centro De Reabilitação Funcional Animal – C.R.A.A.

Hospital Veterinário Da Arrábida

(Sociedade Portuguesa De Ciências Em Animais De Laboratório

Centro De Reabilitação E Regeneração Animal De Lisboa – CR2AL

International ATMO Inc

Simon Fraser University

Instituto Politécnico Da Lusofonia Escola Superior De Saúde Proteção E Bem-Estar Animal

Instituto Politécnico De Portalegre Escola Superior Agrária De Elvas

Universidade De Lisboa Faculdade De Medicina Veterinária

Universidade Do Porto Instituto De Ciências Biomédicas Abel Salazar

Unione Italiana Society Veterinarie

Universidade De Lisboa

Vetarrabida - Clínica Veterinária Lda

Universidade Lusófona De Humanidades E Tecnologias Faculdade De Medicina Veterinária

Related Funding Activities

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