ORCID Profile
0000-0003-0432-2704
Current Organisations
Eawag
,
Vanderbilt University Medical Center
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Publisher: Oxford University Press (OUP)
Date: 22-08-2022
Abstract: Synthesizing heterogeneous findings from different scientific disciplines, thematic fields, and professional sectors is considered to be a critical component of inter- and transdisciplinary research endeavors. However, little is known about the complex interplay between synthesizing heterogeneous findings, leading creative synthesis, and learning about leading and synthesizing. In the present article, we therefore focus on the key interactions between leading and synthesizing, between synthesizing and learning, and between learning and leading in inter- and transdisciplinary contexts and compile a set of 21 principles that guide the interactions between these components. We use these principles to reflect ex post on the benefits and challenges we encountered in developing a nationwide monitoring program for river restoration in Switzerland and draw lessons learned for future inter- and transdisciplinary research endeavors. We conclude that learning and synthesizing do not happen on their own but need to be designed as intentional and purposeful processes.
Publisher: European Respiratory Society (ERS)
Date: 19-06-2024
Publisher: Elsevier BV
Date: 06-2014
Publisher: European Respiratory Society (ERS)
Date: 06-2019
Publisher: Elsevier BV
Date: 05-2019
DOI: 10.1016/J.JACI.2019.01.032
Abstract: The Agency for Healthcare Research and Quality and the National Institute of Allergy and Infectious Diseases organized a workshop to develop trial concepts that could improve the use and effectiveness of aeroallergen immunotherapy (AAIT). Expert groups were formed to accomplish the following tasks: (1) propose a study design to compare the effectiveness and safety of subcutaneous versus sublingual AAIT (2) propose a study design to compare the effectiveness and safety of AAIT by using 1 or a few allergens versus all or most allergens to which a patient is sensitized (3) propose a study design to determine whether AAIT can alter the progression of childhood allergic airways disease and (4) propose a study design to determine the optimal dose and duration of AAIT to achieve maximal effectiveness with acceptable safety. Study designs were presented by the workgroups, extensively discussed at the workshop, and revised for this report. The proposed trials would be of long duration and require large highly characterized patient populations. Scientific caveats and feasibility matters are discussed. These concepts are intended to help the development of clinical trials that can address some of the major questions related to the practice of AAIT for the management and prevention of allergic airways disease.
Publisher: Elsevier BV
Date: 2022
DOI: 10.1016/J.ARBRES.2021.10.003
Abstract: The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g., medication availability). This article summarizes key recommendations from GINA 2021, and the evidence underpinning recent changes. GINA recommends that asthma in adults and adolescents should not be treated solely with short-acting β
Publisher: Wiley
Date: 15-06-2012
Publisher: American Thoracic Society
Date: 15-04-2022
Publisher: Wiley
Date: 2022
DOI: 10.1111/RESP.14174
Abstract: The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g., medication availability). This article summarizes key recommendations from GINA 2021, and the evidence underpinning recent changes. GINA recommends that asthma in adults and adolescents should not be treated solely with short-acting β
Publisher: American Thoracic Society
Date: 2022
Location: United States of America
Location: United States of America
No related grants have been discovered for Leonard Bacharier.