ORCID Profile
0000-0001-5587-1645
Current Organisation
SA Health
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Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 11-2007
DOI: 10.1097/01.CCM.0000284503.88148.6F
Abstract: To quantify the therapeutic efficacy of loop diuretics in acute renal failure using Bayesian evidence synthesis, because despite widespread use, the role of diuretics is controversial. Randomized controlled trials or nonrandomized studies, 1966 to January 2007, identified from MEDLINE and EMBASE databases and manual bibliographic search. Studies with assessable predefined end points, exclusive of those pertaining to acute renal failure prophylaxis or chronic renal failure. Data extraction was performed jointly by the first two authors independent study assessment was via standard checklist, unblinded. The primary outcome was mortality secondary outcomes were time to renal function normalization and total number of dialyses. Bayesian hierarchical random effects estimates of treatment effects were determined as risk ratio for mortality, incidence rate ratio for dialysis number, and mean difference for continuous measures. Bayesian outcome probabilities were calculated as probability (P) that risk ratio or incidence rate ratio of loop diuretics >1 and probability that mean difference >0. Five randomized controlled trials and eight nonrandomized studies were identified. Loop diuretics were not associated with decreased mortality in either randomized controlled trials or nonrandomized studies: overall risk ratio 1.10 95% credible interval 0.85, 1.42 P(risk ratio >1) > 83.8%. The oliguric period was decreased by loop diuretics: overall mean difference -7.70 days 95% credible interval -12.51, -2.08 P (mean difference >0) = 0.7%. Although the dialysis rate credible interval, loop diuretics vs. control, spanned unity (incidence rate ratio 0.71 95% credible interval 0.47, 1.06), the probability that the incidence rate ratio exceeded unity indicated a substantial benefit: P (incidence rate ratio >1 = 4.1%. Uremic duration was not substantially different, loop diuretics vs. control: overall mean difference -1.54 days 95% credible interval -5.62, 2.46 P [mean difference >0] = 17.8%). Loop diuretics were not associated with improved survival benefit in acute renal failure, despite reduction in oliguric period and high probability of a significant reduction in dialysis numbers. Further studies to clarify this dichotomy appear mandated.
Publisher: Springer Science and Business Media LLC
Date: 2010
DOI: 10.1186/CC9182
Publisher: Emerald
Date: 10-2004
DOI: 10.1108/02640470410561965
Abstract: In South Australia, The Queen Elizabeth Hospital (TQEH) was the first health library to commit itself to e‐journals in a significant way. The experience of becoming an electronic library has been closely intertwined with the growth of the South Australian Human Services Libraries Consortium and the trend towards electronic library resources. Between 1999 and 2000 TQEH cancelled all print journals where electronic access was readily available. This paper examines the experiences, benefits, pitfalls, lessons learned and outcomes of committing to electronic resources in TQEH over the last four years and looks at where the future lies for electronic delivery in TQEH.
Publisher: Informa UK Limited
Date: 04-09-2008
Publisher: Wiley
Date: 24-05-2005
DOI: 10.1111/J.1471-1842.2005.00569.X
Abstract: In 2002, a discussion in the United Kingdom (UK) between South-west Information for Clinical Effectiveness (SWICE) librarians and a member of the South Australian Department of Human Services Libraries' Consortium (SAHSLC) raised the possibility of developing an after-hours virtual reference service between the two consortium groups. The aim of the service is to put medical practitioners in contact with a librarian when urgent help is required in finding clinical medical information after hours. A trial project has begun and has been given the name 'Chasing the Sun'. The service will make use of time-zone differences between the UK and Australia, so that librarians at work in another country will be able to answer urgent patient-related queries that cannot wait until normal office hours. This paper looks at the development of 'Chasing the Sun' from initial concept, funding proposal and trial project stage to implementation. It includes details of the groundwork, software evaluation, trials, outcomes, cost and benefits, future directions and potential problems yet to be experienced or overcome. This service is the first of its kind between health libraries in the world and offers potential for future worldwide expansion.
No related grants have been discovered for Sue Rockliff.