ORCID Profile
0000-0002-5867-8741
Current Organisations
National and Kapodistrian University of Athens
,
IT University of Copenhagen
,
Ethniko Metsobio Polytechneio
,
University of Minnesota
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Publisher: Springer Science and Business Media LLC
Date: 03-09-2018
Publisher: Elsevier BV
Date: 12-2011
DOI: 10.1016/J.JCLINEPI.2011.06.004
Abstract: The most common reason for rating up the quality of evidence is a large effect. GRADE suggests considering rating up quality of evidence one level when methodologically rigorous observational studies show at least a two-fold reduction or increase in risk, and rating up two levels for at least a five-fold reduction or increase in risk. Systematic review authors and guideline developers may also consider rating up quality of evidence when a dose-response gradient is present, and when all plausible confounders or biases would decrease an apparent treatment effect, or would create a spurious effect when results suggest no effect. Other considerations include the rapidity of the response, the underlying trajectory of the condition, and indirect evidence.
Publisher: Springer Berlin Heidelberg
Date: 2005
DOI: 10.1007/11431053_9
Publisher: Elsevier BV
Date: 03-2023
Publisher: Wiley
Date: 21-03-2021
Publisher: Elsevier BV
Date: 02-2013
DOI: 10.1016/J.JCLINEPI.2012.01.006
Abstract: GRADE requires guideline developers to make an overall rating of confidence in estimates of effect (quality of evidence-high, moderate, low, or very low) for each important or critical outcome. GRADE suggests, for each outcome, the initial separate consideration of five domains of reasons for rating down the confidence in effect estimates, thereby allowing systematic review authors and guideline developers to arrive at an outcome-specific rating of confidence. Although this rating system represents discrete steps on an ordinal scale, it is helpful to view confidence in estimates as a continuum, and the final rating of confidence may differ from that suggested by separate consideration of each domain. An overall rating of confidence in estimates of effect is only relevant in settings when recommendations are being made. In general, it is based on the critical outcome that provides the lowest confidence.
Publisher: Elsevier BV
Date: 03-2023
Publisher: Korean Society for Sexual Medicine and Andrology
Date: 2022
DOI: 10.5534/WJMH.210155
No related grants have been discovered for Shahnaz Sultan.