ORCID Profile
0000-0002-4792-7386
Current Organisations
University of Technology Sydney
,
King Abdullah University of Science and Technology Department of Electrical Engineering
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Publications
Modelling of multilayer biological medium under molecular communication paradigm
Publisher: IEEE
Date: 12-2017
Influence of Tissue Anisotropy on Molecular Communication
Publisher: IEEE
Date: 07-2019
Modeling of Ligand-Receptor Protein Interaction in Biodegradable Spherical Bounded Biological Micro-Environments
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2018
Wideband RF power meterwith frequency range up to 10 GHz
Publisher: IEEE
Date: 10-2015
Impact of Reactive Obstacle on Molecular Communication between Nanomachines
Publisher: IEEE
Date: 07-2018
Performance analysis of mobile WiMAX communication using directional antenna over fading channel
Publisher: IEEE
Date: 04-2014
Modeling and design of an infrared-based identification (IRID) system-tag and reader design
Publisher: IEEE
Date: 04-2014
Modelling of Implantable Drug Delivery System in Tumor Microenvironment Using Molecular Communication Paradigm
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2019
Implantable Biosensor Interface Platform for Monitoring of Atherosclerosis
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2020
Intrabody Molecular Communication via Blood-Tissue Barrier for Internet of Bio-Nano Things
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 11-2022
Comparison of reception mechanisms for molecular communication via diffusion
Publisher: IEEE
Date: 04-2018
Modelling of combination therapy using implantable anticancer drug delivery with thermal ablation in solid tumor
Publisher: Springer Science and Business Media LLC
Date: 09-11-2020
DOI: 10.1038/S41598-020-76123-0
Abstract: Local implantable drug delivery system (IDDS) can be used as an effective adjunctive therapy for solid tumor following thermal ablation for destroying the residual cancer cells and preventing the tumor recurrence. In this paper, we develop comprehensive mathematical pharmacokinetic harmacodynamic (PK/PD) models for combination therapy using implantable drug delivery system following thermal ablation inside solid tumors with the help of molecular communication paradigm. In this model, doxorubicin (DOX)-loaded implant (act as a transmitter) is assumed to be inserted inside solid tumor (acts as a channel) after thermal ablation. Using this model, we can predict the extracellular and intracellular concentration of both free and bound drugs. Also, Impact of the anticancer drug on both cancer and normal cells is evaluated using a pharmacodynamic (PD) model that depends on both the spatiotemporal intracellular concentration as well as characteristics of anticancer drug and cells. Accuracy and validity of the proposed drug transport model is verified with published experimental data in the literature. The results show that this combination therapy results in high therapeutic efficacy with negligible toxicity effect on the normal tissue. The proposed model can help in optimize development of this combination treatment for solid tumors, particularly, the design parameters of the implant.
Hata Path Loss Model Tuning for Cellular Networks in Irbid City
Publisher: IEEE
Date: 10-2015
Performance analysis of MIMO system over α-μ fading channel for full scheduling scheme
Publisher: IEEE
Date: 10-2015
Modeling a Composite Molecular Communication Channel
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2018
Prediction of radiowave propagation for wireless cellular networks in Jordan
Publisher: IEEE
Date: 2015
Related Organisations
King Abdullah University Of Science And Technology Department Of Electrical Engineering
Location: Saudi Arabia
Related Funding Activities
No related grants have been discovered for Muneer Al-Zubi.