ORCID Profile
0000-0002-8597-5944
Current Organisation
University of Technology Sydney
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Publisher: SPIE-Intl Soc Optical Eng
Date: 15-01-2016
Publisher: IEEE
Date: 03-2023
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2021
Publisher: Springer International Publishing
Date: 2023
Publisher: American Chemical Society (ACS)
Date: 16-03-2023
Publisher: JMIR Publications Inc.
Date: 03-06-2020
Abstract: europathic pain is a debilitating secondary condition for many in iduals with spinal cord injury. Spinal cord injury neuropathic pain often is poorly responsive to existing pharmacological and nonpharmacological treatments. A growing body of evidence supports the potential for brain-computer interface systems to reduce spinal cord injury neuropathic pain via electroencephalographic neurofeedback. However, further studies are needed to provide more definitive evidence regarding the effectiveness of this intervention. he primary objective of this study is to evaluate the effectiveness of a multiday course of a brain-computer interface neuromodulative intervention in a gaming environment to provide pain relief for in iduals with neuropathic pain following spinal cord injury. e have developed a novel brain-computer interface-based neuromodulative intervention for spinal cord injury neuropathic pain. Our brain-computer interface neuromodulative treatment includes an interactive gaming interface, and a neuromodulation protocol targeted to suppress theta (4-8 Hz) and high beta (20-30 Hz) frequency powers, and enhance alpha (9-12 Hz) power. We will use a single-case experimental design with multiple baselines to examine the effectiveness of our self-developed brain-computer interface neuromodulative intervention for the treatment of spinal cord injury neuropathic pain. We will recruit 3 participants with spinal cord injury neuropathic pain. Each participant will be randomly allocated to a different baseline phase (ie, 7, 10, or 14 days), which will then be followed by 20 sessions of a 30-minute brain-computer interface neuromodulative intervention over a 4-week period. The visual analog scale assessing average pain intensity will serve as the primary outcome measure. We will also assess pain interference as a secondary outcome domain. Generalization measures will assess quality of life, sleep quality, and anxiety and depressive symptoms, as well as resting-state electroencephalography and thalamic γ-aminobutyric acid concentration. his study was approved by the Human Research Committees of the University of New South Wales in July 2019 and the University of Technology Sydney in January 2020. We plan to begin the trial in October 2020 and expect to publish the results by the end of 2021. his clinical trial using single-case experimental design methodology has been designed to evaluate the effectiveness of a novel brain-computer interface neuromodulative treatment for people with neuropathic pain after spinal cord injury. Single-case experimental designs are considered a viable alternative approach to randomized clinical trials to identify evidence-based practices in the field of technology-based health interventions when recruitment of large s les is not feasible. ustralian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12620000556943 bit.ly/2RY1jRx RR1-10.2196/20979
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2021
Publisher: JMIR Publications Inc.
Date: 29-09-2020
DOI: 10.2196/20979
Abstract: Neuropathic pain is a debilitating secondary condition for many in iduals with spinal cord injury. Spinal cord injury neuropathic pain often is poorly responsive to existing pharmacological and nonpharmacological treatments. A growing body of evidence supports the potential for brain-computer interface systems to reduce spinal cord injury neuropathic pain via electroencephalographic neurofeedback. However, further studies are needed to provide more definitive evidence regarding the effectiveness of this intervention. The primary objective of this study is to evaluate the effectiveness of a multiday course of a brain-computer interface neuromodulative intervention in a gaming environment to provide pain relief for in iduals with neuropathic pain following spinal cord injury. We have developed a novel brain-computer interface-based neuromodulative intervention for spinal cord injury neuropathic pain. Our brain-computer interface neuromodulative treatment includes an interactive gaming interface, and a neuromodulation protocol targeted to suppress theta (4-8 Hz) and high beta (20-30 Hz) frequency powers, and enhance alpha (9-12 Hz) power. We will use a single-case experimental design with multiple baselines to examine the effectiveness of our self-developed brain-computer interface neuromodulative intervention for the treatment of spinal cord injury neuropathic pain. We will recruit 3 participants with spinal cord injury neuropathic pain. Each participant will be randomly allocated to a different baseline phase (ie, 7, 10, or 14 days), which will then be followed by 20 sessions of a 30-minute brain-computer interface neuromodulative intervention over a 4-week period. The visual analog scale assessing average pain intensity will serve as the primary outcome measure. We will also assess pain interference as a secondary outcome domain. Generalization measures will assess quality of life, sleep quality, and anxiety and depressive symptoms, as well as resting-state electroencephalography and thalamic γ-aminobutyric acid concentration. This study was approved by the Human Research Committees of the University of New South Wales in July 2019 and the University of Technology Sydney in January 2020. We plan to begin the trial in October 2020 and expect to publish the results by the end of 2021. This clinical trial using single-case experimental design methodology has been designed to evaluate the effectiveness of a novel brain-computer interface neuromodulative treatment for people with neuropathic pain after spinal cord injury. Single-case experimental designs are considered a viable alternative approach to randomized clinical trials to identify evidence-based practices in the field of technology-based health interventions when recruitment of large s les is not feasible. Australian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12620000556943 bit.ly/2RY1jRx PRR1-10.2196/20979
Publisher: IEEE
Date: 12-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2022
Publisher: Cold Spring Harbor Laboratory
Date: 02-12-2020
DOI: 10.1101/2020.12.01.406124
Abstract: Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants’ movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we investigated neural dynamics of RSC in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.
Publisher: Cold Spring Harbor Laboratory
Date: 08-03-2021
DOI: 10.1101/2021.03.05.434173
Abstract: This study investigates the effects of collaboration on task performance in brain-computer interface (BCI) based on steady-state visually evoked potential (SSVEP). Navigation tasks were performed in a virtual environment under two conditions, e.g., in idual performance and team performance. The results showed that average task completion time in the collaborative condition is decreased by 6 percent compared with that of in idual performance, which is inline with other studies in collaborative BCI (cBCI) and joint decision-making. Our work is a step forward for the progress in BCI studies that include multi-user interactions.
Location: Korea, Republic of
No related grants have been discovered for Thomas Do.