ORCID Profile
0000-0002-8056-0723
Current Organisations
George Mason University
,
Nong Lam University
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Elsevier BV
Date: 12-2021
Publisher: Oxford University Press (OUP)
Date: 12-07-2021
Abstract: Development of antimicrobial use (AMU) surveillance systems in humans and animals is a priority for many low- and middle-income countries however accurate estimations are h ered by a ersity of animal production systems and metrics. The Mekong Delta region of Vietnam is a ‘hotspot’ of antimicrobial resistance and is home to a high density of humans and animal populations. To measure and compare AMU using different metrics (standing population, biomass and population correction unit) in the Mekong Delta, and to explore the potential of field-based data collection methods in the design of AMU surveillance systems. We collected AMU data from humans and animals (chickens, ducks, Muscovy ducks, pigs) from 101 small-scale farms in the Mekong Delta over a fixed period (90 days in humans, 7 days in animals). Humans used 7.1 DDDkg, or 175.9 mg of antimicrobial active ingredients (AAIs) per kg of standing body mass annually animals consumed 60.9 ADDkg or 1324 mg. In the Mekong Delta humans represented 79.3% of the total body mass but consumed 29.6% of AAIs by weight. AAIs regarded of critical importance by WHO represented 56.9% and 50.2% of doses consumed by animals and humans, respectively. Using a One Health approach, we show that AMU can potentially be estimated from cross-sectional surveys, although results are hypothetical due to small s le size and are sensitive to the chosen population denominator. The methodology proposed here can potentially be scaled up be applied to design AMU surveillance in low-resource settings, allowing AMU reduction efforts to be focused on particular animal species.
Publisher: Informa UK Limited
Date: 18-09-2023
Publisher: Informa UK Limited
Date: 16-03-2023
Publisher: Frontiers Media SA
Date: 21-06-2019
Publisher: Springer Science and Business Media LLC
Date: 19-08-2022
DOI: 10.1007/S44168-022-00021-6
Abstract: Climate change is a complex social-political issue in Australia with a history of dysfunctional conflict over climate policy. This presents challenges for the practitioners communicating about climate change to different publics. To date, academic research has focused on exploring how effective communication can be achieved but rarely has this been understood from a practitioner’s perspective. I present the findings of nineteen ( n = 19) semi-structured interviews with climate change communication (CCC) practitioners in Australia. The interviews explored occupational experiences as a means to understand the state of practice, challenges, and ways forward for CCC. I explore four key themes in this analysis: the practitioners, their goals, the barriers, and their perspectives on framing. Participants spoke of the complexity in doing CCC work, including many barriers, but their focus on effective communication and engagement remains strong in the face of challenging circumstances. Graphical abstract
Publisher: Wiley
Date: 02-05-2021
DOI: 10.1111/ZPH.12839
Abstract: Antimicrobials are extensively used both prophylactically and therapeutically in poultry production. Despite this, there are little data on the effect of antimicrobial use (AMU) on disease incidence rate and per cent mortality. We investigated the relationships between AMU and disease and between AMU and mortality using data from a large ( n = 322 flocks) cohort of small‐scale chicken flocks in the Mekong Delta, Vietnam, that were followed longitudinally from day old to slaughter (5,566 observation weeks). We developed a parameterized algorithm to emulate a randomized control trial from observational data by categorizing the observation weeks into ‘non‐AMU’, ‘prophylactic AMU’ and ‘therapeutic AMU’. To evaluate the prophylactic AMU effect, we compared the frequencies of clinical signs in ‘non‐AMU’ and ‘prophylactic AMU’ periods. To analyse therapeutic AMU, we compared weekly per cent mortality between the weeks of disease episodes before and after AMU. Analyses were stratified by clinical signs (4) and antimicrobial classes (13). Prophylactic AMU never reduced the probability of disease, and some antimicrobial classes such as lincosamides, henicols and penicillins increased the risk. The risk of diarrhoea consistently increased with prophylactic AMU. Therapeutic AMU often had an effect on mortality, but the pattern was inconsistent across the combinations of antimicrobial classes and clinical signs with 14/29 decreasing and 11/29 increasing the per cent weekly mortality. Lincosamides, methenamines and cephalosporins were the only three antimicrobial classes that always decreased the mortality when used therapeutically. Results were robust respective to the parameters values of the weeks categorization algorithm. This information should help support policy efforts and interventions aiming at reducing AMU in animal production.
Publisher: MDPI AG
Date: 10-08-2020
DOI: 10.3390/ANTIBIOTICS9080499
Abstract: In the Mekong Delta of Vietnam, farmers use large quantities of antimicrobials to raise small-scale chicken flocks, often including active ingredients regarded of “critical importance’” by the World Health Organization. Due to limitations in laboratory capacity, the choice of antimicrobials normally does not follow any empirical criteria of effectiveness. The aim of this study was to highlight non-critically important antimicrobials against which chicken pathogens are likely to be susceptible as a basis for treatment guidelines. Microtiter broth dilution method was performed to determine the minimal inhibitory concentration (MIC) of 12 commonly used antimicrobials for 58 isolates, including Ornithobacterium rhinotracheale (ORT) (n = 22), Gallibacterium anatis (n = 19), and Avibacterium endocarditidis (n = 17). Unfortunately, internationally accepted breakpoints for resistance in these organisms do not exist. We drew tentative epidemiological cut-offs (TECOFFs) for those antimicrobial-pathogen combinations where MIC distributions suggested the presence of a distinct non-wild-type population. Based on the observed results, doxycycline would be the drug of choice for A.endocarditidis (11.8% presumptive non-wild type) and G. anatis infections (5.3% presumptive non-wild type). A total of 13.6% ORT isolates were non-wild type with regards to oxytetracycline, making it the drug of choice against this pathogen. This study illustrates the challenges in interpreting susceptibility testing results and the need to establish internationally accepted breakpoints for veterinary pathogens.
Publisher: Springer Science and Business Media LLC
Date: 14-01-2020
DOI: 10.1186/S12992-019-0539-X
Abstract: In the Mekong Delta region of Vietnam, high quantities of products containing antimicrobial are used as prophylactic and curative treatments in small-scale chicken flocks. A large number of these contain antimicrobial active ingredients (AAIs) considered of ‘critical importance’ for human medicine according to the World Health Organization (WHO). However, little is known about the retail prices of these products and variables associated with the expense on antimicrobials at farm level. Therefore, the aims of the study were: (1) to investigate the retail price of antimicrobials with regards to WHO importance criteria and (2) to quantify the antimicrobial expense incurred in raising chicken flocks. We investigated 102 randomly-selected small-scale farms raising meat chickens (100–2000 per flock cycle) in two districts in Dong Thap (Mekong Delta) over 203 flock production cycles raised in these farms. Farmers were asked to record the retail prices and amounts of antimicrobial used. A total of 214 different antimicrobial-containing products were identified. These contained 37 different AAIs belonging to 13 classes. Over half (60.3%) products contained 1 highest priority, critically important AAI, and 38.8% 1 high priority, critically important AAI. The average (farm-adjusted) retail price of a daily dose administered to a 1 kg bird across products was 0.40 cents of 1 US$ (₵) (SE ± 0.05). The most expensive products were those that included at least one high priority, critically important AAI, as well as those purchased in one of the two study districts. Farmers spent on average of ₵3.91 (SE ± 0.01) on antimicrobials per bird over the production cycle. The expense on antimicrobials in weeks with disease and low mortality was greater than on weeks with disease and high mortality, suggesting that antimicrobial use had a beneficial impact on disease outcomes ( χ 2 = 3.8 p = 0.052). Farmers generally used more expensive antimicrobials on older flocks. The retail prices of antimicrobial products used in chicken production in Mekong Delta small-scale chicken farms are very low, and not related to their relevance for human medicine. Farmers, however, demonstrated a degree of sensitivity to prices of antimicrobial products. Therefore, revising pricing policies of antimicrobial products remains a potential option to curb the use of antimicrobials of critical importance in animal production.
Publisher: Frontiers Media SA
Date: 15-07-2020
Publisher: IOP Publishing
Date: 23-11-2020
Abstract: Climate change emerged as an issue of science, but its broad ranging impacts and potential mitigation strategies mean it is of significance to all people across sectors, interests, and nations. As a result, the traditional fact-centred way of communicating information about climate change is not necessarily the best strategy for engaging the full breadth of publics. In communication practice and scholarship, framing is an approach that emphasises certain attributes of an issue over others and as a consequence shapes how that issue is understood. This has led to the scholarly exploration of framing as a technique for tailoring climate change communication to engage erse publics. Over the past two decades, research has examined a range of different frames for the communication of climate change, such as Public health, National security and Economic prosperity/development . With this literature now rapidly expanding, it is crucial to synthesise existing evidence so that future research efforts and climate communication interventions are best informed about the current knowledge-base and research gaps. This article presents this synthesis in the form of a systematic map. We systematically searched scholarly (Scopus and Web of Science) and grey literature databases for English-language climate change framing literature. All articles were screened at the title/abstract and full-text level, with included articles incorporated into a Microsoft (MS) Excel database. The information extracted from the literature included bibliometric, geographical and other data pertaining to study design and the climate change frames examined. Our systematic map includes 274 articles (281 studies). The most common frames appearing in this literature base (making up about 50% of the total) were Scientific, Economic and Environmental . Other frames such as Public health, Disaster and Morality/ethics appear to be gaining more scholarly attention in recent years. Almost half of the collected studies are from the United States but there is a growing trend of studies comparing climate change frames from other countries. Climate change frames are numerous and can have different efficacies depending upon country and social-political context. Research needs to be reflexive in its approach to understand the broader impact of framing in climate change communication and should continue to employ multi-national studies and explore climate change framing effects in under-researched nations to combat bias.
Location: Viet Nam
No related grants have been discovered for Doan Hoang Phu.