ORCID Profile
0000-0003-2046-8957
Current Organisations
The University of Auckland
,
Auckland District Health Board
,
Royal Australasian College of Physicians
,
Royal Australasian College of Medical Administrators
,
University of Otago
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Publisher: EDP Sciences
Date: 10-2018
DOI: 10.1051/0004-6361/201832992
Abstract: Context . Absorbing galaxies are selected via the detection of characteristic absorption lines which their gas-rich media imprint in the spectra of distant light-beacons. The proximity of the typically faint foreground absorbing galaxies to bright background sources makes it challenging to robustly identify these in emission, and hence to characterise their relation to the general galaxy population. Aims . We search for emission to confirm and characterise ten galaxies hosting d ed, metal-rich quasar absorbers at redshift z 1. Methods . We identified the absorbing galaxies by matching spectroscopic absorption -and emission redshifts and from projected separations. Combining emission-line diagnostics with existing absorption spectroscopy and photometry of quasar-fields hosting metal-rich, d ed absorbers, we compare our new detections with reference s les and place them on scaling relations. Results . We spectroscopically confirm seven galaxies harbouring d ed absorbers (a 70% success-rate). Our results conform to the emerging picture that neutral gas on scales of tens of kpc in galaxies is what causes the characteristic H I absorption. Our key results are: (I) Absorbing galaxies with log 10 [ M ⋆ ,( M ⊙ )] ≳ 10 have star formation rates that are lower than predicted for the main sequence of star formation. (II) The distribution of impact parameter with H I column density and with absorption-metallicity for absorbing galaxies at z ∼ 2–3 extends to z ∼ 0.7 and to lower H I column densities. (III) A robust mean metallicity gradient of ⟨Γ⟩ = −0.022 ± 0.001 dex kpc −1 . (IV) By correcting absorption metallicities for ⟨Γ⟩ and imposing a truncation-radius at 12 kpc, absorbing galaxies fall on top of predicted mass-metallicity relations, with a statistically significant decrease in scatter.
Publisher: Wiley
Date: 20-08-2018
DOI: 10.1111/RESP.13386
Publisher: Wiley
Date: 07-2018
DOI: 10.1111/IMJ.13739
Abstract: This study evaluated whether there are ethnic factors which affect the severity and progression of bronchiectasis in our adult multi-ethnic population in Auckland, New Zealand. Clinical records were reviewed from patients attending the outpatient facilities of our institution between 2007 and 2010. Data collected included demographics, clinical features, smoking status, self-reported ethnicity, socioeconomic status (NZDep), pulmonary function and sputum microbiology. A total of 437 patients was identified: median age 65 years, 66% female, mean forced expiratory volume in the first second (FEV Patients of Maori and Pacific ethnicity are both overrepresented and have more severe bronchiectasis in this cohort, independent of socioeconomic status. Ethnicity did not predict decline in pulmonary function. Further studies into genetic predisposition to bronchiectasis in Maori or Pacific people may be warranted.
Publisher: Cambridge University Press
Date: 10-06-2005
Publisher: Elsevier BV
Date: 05-2023
Publisher: Elsevier BV
Date: 09-2021
DOI: 10.1016/J.AJO.2021.03.003
Abstract: To examine systemic associations of sarcoid uveitis and association with uveitis clinical phenotype and ethnicity. Retrospective cross-sectional study. A total of 362 subjects with definite or presumed sarcoid uveitis from Moorfields Eye Hospital, Royal Victorian Eye and Ear, and Auckland District Health Board. Data were collected from the review of clinical notes, imaging, and investigations. Sarcoidosis was diagnosed in accordance with the International Workshop on Ocular Sarcoidosis guidelines. Diagnosis of associated systemic disease secondary to sarcoidosis. A total of 362 subjects with sarcoid uveitis were identified. Median age was 46 years, and 226 (62.4%) were female. Granulomatous anterior uveitis (47.8%), intermediate uveitis with snowballs (46.4%), and multifocal choroiditis (43.1%) were the most frequent clinical presentations, and disease was bilateral in 313 (86.5%). Periphlebitis was observed in 21.0%, and solitary optic nerve or choroidal granuloma in 11.3%. Lung parenchymal disease was diagnosed in 200 subjects (55.2%), cutaneous sarcoid in 98 (27.1%), sarcoid arthritis in 57 (15.7%), liver involvement in 21 (5.8%), neurosarcoid in 49 (13.5%), and cardiac sarcoid in 16 subjects (4.4%). Subjects with cardiac sarcoid were less likely to have granulomatous anterior uveitis (P = .017). Caucasian subjects were older at presentation (48 vs 41 years P = .009), had less granulomatous anterior uveitis (26.4% vs 51.7% P < .001), and were less likely to present with cutaneous involvement (23.1% vs 35.4% P = .040). Ophthalmologists need to be aware of the systemic associations of sarcoid uveitis, in particular potentially life-threatening complications such as cardiac sarcoidosis. Differences observed in uveitis phenotype and between ethnicities require further investigation.
Publisher: Wiley
Date: 09-02-2022
DOI: 10.1111/RESP.14219
Abstract: See related article
Publisher: Wiley
Date: 24-11-2020
DOI: 10.1111/RESP.13977
Location: Australia
No related grants have been discovered for Margaret Wilsher.