ORCID Profile
0000-0002-3033-4840
Current Organisations
University of California Davis
,
University of Glasgow
,
King Saud University
,
The University of Newcastle
,
University of Newcastle Australia
,
Islamic University
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Herbert Publications PVT LTD
Date: 2013
Publisher: Elsevier BV
Date: 07-2021
Publisher: Elsevier BV
Date: 07-2021
Publisher: Journal of Applied Pharmaceutical Science
Date: 2015
Publisher: Springer Science and Business Media LLC
Date: 27-03-2019
Publisher: Springer Science and Business Media LLC
Date: 29-06-2022
DOI: 10.1007/S11270-022-05711-9
Abstract: Lead (Pb) is a widely occurring heavy metal employed in industrial products and hence released into the environment, causing several environmental health risk concerns. This study comprehensively surveyed the literature on Pb contamination in different agricultural foods and food products commonly consumed by Bangladeshi inhabitants and assessed associated cancer and non-cancer health risks. Cereals (i.e., rice, wheat and maize) contained very high concentrations of Pb among the selected food items, the highest was found in wheat (4.04 µg g −1 ), while rice and maize were 2.22 and 1.43 µg g −1 , respectively, that exceeded the maximum allowable concentration (MAC, 0.20 µg g −1 ) for cereals. Vegetables contained higher Pb than the MAC of 0.01 µg g −1 , except for mushroom, green banana, cauliflower and arum. In addition, pulses also contained a moderate amount of Pb however, fruits contained a low level of Pb, except for mangoes. When examining spatial differences in Pb contamination, most districts exhibited high Pb content in cereals however, vegetables of the Tangail district exhibited the highest Pb concentrations (2.17 µg g −1 ), originating from industrial operations and vehicular emissions. In terms of human health risk assessment, it was observed that consumption of rice, zucchini, tesla gourd, sponge gourd, okra, drumstick lib, chili and cabbage might pose non-cancer health risks (THQs 1) however, fruits and pulses do not pose any non-cancer health risks to Bangladeshi residents. Most of the cereals and vegetables showed a higher value than 10 −6 , indicating a potential cancer risk however, fruits and pulses showed lower risk only marginally exceeding the lower allowable limit (i.e., 10 −6 ). Graphical abstract
Publisher: American Institute of Mathematical Sciences (AIMS)
Date: 2018
Publisher: Elsevier BV
Date: 02-2023
Publisher: Elsevier BV
Date: 05-2019
DOI: 10.1016/J.ENVPOL.2019.02.056
Abstract: Estrogenic endocrine disrupting chemicals (EDCs) are natural hormones, synthetic compounds or industrial chemicals that mimic estrogens due to their structural similarity with estrogen's functional moieties. They typically enter aquatic environments through wastewater treatment plant effluents or runoff from intensive livestock operations. Globally, most natural and synthetic estrogens in receiving aquatic environments are in the low ng/L range, while industrial chemicals (such as bisphenol A, nonylphenol and octylphenol) are present in the μg to low mg/L range. These environmental concentrations often exceed laboratory-based predicted no effect concentrations (PNECs) and have been evidenced to cause negative reproductive impacts on resident aquatic biota. In vertebrates, such as fish, a well-established indicator of estrogen-mediated endocrine disruption is overexpression of the egg yolk protein precursor vitellogenin (Vtg) in males. Although the vertebrate Vtg has high sensitivity and specificity to estrogens, and the molecular basis of its estrogen inducibility has been well studied, there is growing ethical concern over the use of vertebrate animals for contaminant monitoring. The potential utility of the invertebrate Vtg as a biomonitor for environmental estrogens has therefore gained increasing attention. Here we review evidence providing support that the molluscan Vtg holds promise as an invertebrate biomarker for exposure to estrogens. Unlike vertebrates, estrogen signalling in invertebrates remains largely unclarified and the classical genomic pathway only partially explains estrogen-mediated activation of Vtg. In light of this, in the latter part of this review, we summarise recent progress towards understanding the molecular mechanisms underlying the activation of the molluscan Vtg gene by estrogens and present a hypothetical model of the interplay between genomic and non-genomic pathways in the transcriptional regulation of the gene.
Publisher: Elsevier BV
Date: 02-2021
Publisher: Elsevier BV
Date: 04-2020
DOI: 10.1016/J.SCITOTENV.2020.136576
Abstract: Remnant endangered saltmarsh communities in Australia often occur in urbanised estuaries where industrial processes have contaminated sediments with metal(loid)s. Despite this issue, virtually nothing is known on local plant species exposure to metal contaminants, nor their ability to uptake and translocate metal(loid)s from contaminated estuarine sediment. In the current study, we assessed the accumulation and partitioning of the metal(loid)s Zn, Cu, Pb, Cd and Se in the dominant saltmarsh primary producer, Sporobolus virginicus, across three urbanised estuaries in NSW Australia. Lake Macquarie was the most contaminated estuary, while Sydney Olympic Park, Port Jackson exhibited intermediate metal(loid) loadings and Hunter Wetlands exhibited the lowest loadings among estuaries. Essential metals (Zn and Cu) were more mobile, with sediment:root bioconcentration factors (BCFs) greater than unity and translocation among plant organs greater than, or equal to, unity. Other metal(loid)s were less mobile, with BCFs equal to unity and translocation factors among organs much reduced. Despite these barriers to translocation, all metal(loid)s were accumulated to roots with dose, and further accumulative relationships between metal(loid)s in roots and culms, and culms and leaves, were evidenced (with the exception of Cu). Along with sediment metal(loid)s, increases in sediment pH predicted Cu uptake in roots and increases in soil organic matter predicted Se uptake in roots. Although significant positive linear relationships were observed between sediment metal(loid)s and plant organ metal(loid)s(withholding Cu), the variance explained was low to intermediate for most metal(loid)s suggesting employing S. virginicus as an accumulative bioindicator would be impractical.
Publisher: Faculty of Engineering, Chulalongkorn University
Date: 07-2013
Publisher: Academic Journals
Date: 31-01-2016
Publisher: Central Fisheries Research Institute (SUMAE)
Date: 2013
Publisher: OMICS Publishing Group
Date: 2012
Publisher: Informa UK Limited
Date: 03-09-2015
Publisher: Elsevier BV
Date: 11-2020
Publisher: Elsevier BV
Date: 05-2017
Publisher: Elsevier BV
Date: 11-2018
Publisher: Massachusetts Medical Society
Date: 29-04-2010
DOI: 10.1056/NEJMC0908038
Publisher: Springer Science and Business Media LLC
Date: 1985
DOI: 10.1007/BF00391033
Publisher: American Institute of Mathematical Sciences (AIMS)
Date: 2018
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0FO00350F
Abstract: This study explored plasma levels and urinary and fecal excretion of metabolites and microbial-derived catabolites over a 24 h period following the ingestion of red wine (RWP) or grape seed (GSP) proanthocyanidin-rich extracts by rats.
Publisher: Oxford University Press (OUP)
Date: 1985
DOI: 10.1093/JXB/36.1.99
Publisher: Wiley
Date: 1983
Publisher: Elsevier BV
Date: 03-2022
DOI: 10.1016/J.CHEMOSPHERE.2021.132997
Abstract: This study aimed to reveal possible alterations to lipidomic profiles in Sydney rock oysters, Saccostrea glomerata, exposed to estrogenic mixtures (i.e., estrone, E1 17β-estradiol, E2 estriol, E3 17α-ethinylestradiol, EE2 bisphenol A, BPA 4-t-octylphenol, 4-t-OP and 4-nonylphenol, 4-NP) at "low" and "high" concentrations, typical of those detected in Australian and global receiving waters. A seven-day acute exposure window exhibited significantly lower abundances of many non-polar metabolites in digestive gland, gills, and gonads. Overall, there was a strong effect of the carrier solvent ethanol (despite a low exposure of 0.0002%), with all solvent containing treatments exhibiting lower abundances of lipidic metabolites, especially in the gill and digestive gland. No significant changes of the lipidome were exhibited in the male gonad by estrogenic exposure. However, in the female gonad, significant reductions of phospholipids and phosphatidylcholine were associated with exposure to high estrogenic mixtures. We hypothesise that the decreases in these phospholipids in the female gonad may be attributable to 1) lower algal consumption and thus lower uptake of lipidic building blocks 2) a reduction of available substrates for phospholipid and phosphatidylcholine synthesis and/or 3) induction of reactive oxygen species via estrogen metabolism, which may cause lipid peroxidation and lower abundance of phospholipids.
Location: United Kingdom of Great Britain and Northern Ireland
Start Date: 2017
End Date: End date not available
Funder: University of Newcastle Australia
View Funded Activity