ORCID Profile
0000-0001-8163-7772
Current Organisation
University of Houston
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Informa UK Limited
Date: 23-08-2022
DOI: 10.1080/23279095.2022.2114356
Abstract: We translated the Medication Management Ability Assessment (MMAA) from English to Spanish for use via tele-assessment and examined its reliability and validity. Following International Test Commission Guidelines for Translating and Adapting Tests, we used translation/back-translation and a small focus group (
Publisher: Informa UK Limited
Date: 02-11-2020
Publisher: American Psychological Association (APA)
Date: 22-04-2021
DOI: 10.1037/NEU0000727
Publisher: American Psychological Association (APA)
Date: 2021
DOI: 10.1037/NEU0000705
Publisher: Springer Science and Business Media LLC
Date: 02-10-2018
DOI: 10.1038/S41598-018-32924-Y
Abstract: Evidence from small-scale studies indicates that impairments in postural stability are an early and disabling feature of Huntington’s disease (HD) and may be a useful clinical endpoint for disease modifying trials. Larger studies are needed to confirm these preliminary findings and the suitability of postural stability outcomes as clinical endpoints. Static and dynamic postural stability were evaluated in 54 premanifest HD, 36 manifest HD and 45 healthy in iduals using the Sensory Organization Test (SOT) and Limits of Stability (LOS) test. Manifest HD displayed significantly lower scores on all SOT conditions and on the SOT composite score and had more falls than healthy and premanifest HD (p 0.05). Premanifest and manifest HD demonstrated significantly lower endpoint excursion (p 0.001), maximum excursion (p ≤ 0.001), and directional control (p ≤ 0.004) values than healthy in iduals on the LOS test. Deficits in LOS were found to manifest on the left side of premanifest HD. Significant but low associations were observed between UHDRS-TMS, disease burden score, diagnostic confidence level, SOT conditions and SOT composite score. We confirm here that in iduals with premanifest and manifest HD display significant impairments in static and dynamic postural stability. Dynamic posturography assessments should be considered as clinical endpoints for future disease modifying trials.
Location: United States of America
Location: United States of America
No related grants have been discovered for Luis D Medina.