ORCID Profile
0000-0002-7394-2029
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Informa UK Limited
Date: 13-08-2016
DOI: 10.3109/02713683.2015.1056375
Abstract: The goal of this study was to provide the empirical evidence of fractal dimension as an indirect measure of retinal vasculature density. Two hundred retinal s les of right eye [57.0% females (n = 114) and 43.0% males (n = 86)] were selected from baseline visit. A custom-written software was used for vessel segmentation. Vessel segmentation is the process of transforming two-dimensional color images into binary images (i.e. black and white pixels). The circular area of approximately 2.6 optic disc radii surrounding the center of optic disc was cropped. The non-vessels fragments were removed. FracLac was used to measure the fractal dimension and vessel density of retinal vessels. This study suggested that 14.1% of the region of interest (i.e. approximately 2.6 optic disk radii) comprised retinal vessel structure. Using correlation analysis, vessel density measurement and fractal dimension estimation are linearly and strongly correlated (R = 0.942, R(2) = 0.89, p < 0.001). Polynomial regression model suggests quadratic regression as the best fit for our data (linear: R(2) = 0.1024, 198 d.f., p < 0.001, quadratic: R(2) = 0.1236, 197 d.f., p < 0.001, cubic: R(2) = 0.1236, 196 d.f., p < 0.001). This study demonstrated the ability of vessel density measurement to detect the changes in the morphology of retinal microvascular associated with increasing age. Thus, vessel density can be suggested to be another parameter in the quantification of retinal microvasculature.
Publisher: Hindawi Limited
Date: 2014
DOI: 10.1155/2014/783525
Abstract: Objective . The aim of this study was to compare the retinal vasculature complexity between emmetropia, and myopia in younger subjects. Methods . A total of 82 patients ( 24.12 ± 1 . 25 years) with two types of refractive conditions, myopia and emmetropia were enrolled in this study. Refraction data were converted to spherical equivalent refraction. These retinal images (right eyes) were obtained from NAVIS Lite Image Filing System and the vasculature complexity was measured by fractal dimension ( D f ), quantified using a computer software following a standardized protocol. Results . There was a significant difference ( P 0.05 ) in the value of D f between emmetropic ( 1.5666 ± 0.0160 ) and myopic ( 1.5588 ± 0.0142 ) groups. A positive correlation ( rho = 0.260 , P 0.05 ) between the D f and the spherical equivalent refraction was detected in this study. Using a linear model, it was estimated that 6.7% of the variation in D f could be explained by spherical equivalent refraction. Conclusions . This study provides valuable findings about the effect of moderate to high myopia on the fractal dimension of the retinal vasculature network. These results show that myopic refraction in younger subjects was associated with a decrease in D f , suggesting a loss of retinal vessel density with moderate to high myopia.
Publisher: Elsevier BV
Date: 07-2020
Location: No location found
No related grants have been discovered for Ilyanoon Zahari.