ORCID Profile
0000-0001-5403-2161
Current Organisations
Universitas Muhammadiyah Surabaya
,
Universitas Muhammadiyah Yogyakarta
,
Institut Ilmu Kesehatan Bhakti Wiyata Kediri
,
Taipei Medical University
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Publisher: MDPI AG
Date: 10-2020
Abstract: Alkaline electrolyzed water (AEW) and walking are strongly recommended for ameliorating oxidative stress and inflammation. Nevertheless, there is a lack of information on the combination of both on alleviating inflammation, oxidative stress, and improving the quality of life (QoL). We investigated the synergistic effects of drinking AEW and walking on advanced glycation end products (AGEs), advanced oxidation protein products (AOPPs), malondialdehyde (MDA), white blood cells (WBCs), neutrophil-lymphocyte ratio (NLR) and QoL. In total, 81 eligible patients with type 2 diabetes (T2DM) were randomly allocated via single blind to four groups: consumed 2 L/day of AEW (n = 20), instructed to walk for 150 min/week (n = 20), received a combination of AEW and walking (n = 20), and continue their habitual diet and activity (n = 21). Data were collected and analyzed before and after 8 weeks of intervention. Our results showed a significant interaction between the group and time, with both AEW and walking independently and synergistically ameliorating AGEs, AOPPs, MDA, NLR and WBCs levels. Moreover, the AEW group had a higher physical and total QoL score. The walking group and the combined group had higher scores in physical, mental and total QoL compared to the control group. The synergistic effect of AEW and regular walking are an advisable treatment for patients with T2DM.
Publisher: LPPM STIKes Prima Nusantara Bukittinggi
Date: 18-01-2021
Abstract: Latar Belakang: Organisasi Kesehatan Dunia (WHO) menyatakan bahwa Penyakit Coronavirus 2019 dikategorikan sebagai pandemi global.Hingga tanggal 31 Maret 2020, jumlah positif Covid -19 di Indonesia sebanyak 1.528 kasus, pasien sembuh 81 orang , meninggal dunia sebanyak 136 orang. Tindakan penanggulangan COVID-19 masih tetap berlanjut s ai saat ini, dibutuhkan kepatuhan masyarakat terhadap langkah-langkah upaya yang dilakukan, yang sebagian besar dipengaruhi oleh pengetahuan, sikap, dan tindakan masyarakat terhadap COVID-19.Tujuan : Mengetahui gambaran distribusi frekuensi pengetahuan, sikap dan tindakan masyarakat Indonesia Bagian Barat selama Pandemi Covid 19.Metode : Metode kuantitatif dengan jumlah s el adalah masyarakat Indonesia Bagian Barat sebanyak 817 orang. Teknik pengambilan s el menggunakan random s ling.Hasil: Hasil analisa data univariat diperoleh sebagian besar pengetahuan masyarakat Indonesia Bagian Barat selama pandemi Covid 19 adalah berpengetahuan baik yaitu sejumlah 581 orang (71,1%), sebagian besar sikap masyarakat Indonesia Bagian Barat Selama Pandemic Copid 19 adalah sikap positif yaitu sejumlah 761 orang (93,1%), sebagian besar tindakan masyarakat Indonesia Bagian Barat Selama Pandemic Covid 19 adalah tindakan positif yaitu sejumlah 607 orang (74,3%).Kesimpulan : Sebagian besar masyarakat Indonesia Bagian Barat memiliki pengetahuan yang baik, sikap yang positif dan tindakan yang positif sebagai upaya untuk mencegah penularan COVID-19
Publisher: MDPI AG
Date: 06-08-2020
Abstract: Secondhand smoke (SHS) and physical inactivity are thought to be associated with type 2 diabetes mellitus (T2DM), but the synergistic effect of SHS with physical inactivity and their relationships with T2DM–associated inflammation biomarkers have not been estimated. We investigated the roles of SHS exposure and physical inactivity and their synergistic effect on T2DM risk and their relationships with T2DM associated inflammation biomarkers, neutrophil–lymphocyte ratio (NLR) and white blood cells (WBCs). A case–control study was conducted in total 588 participants (294 case T2DM and 294 healthy controls) from five community clinics in Indonesia. Participants completed a standardized questionnaire on demographic information, smoking status, physical activity habits and food consumption. WBCs and NLR levels were determined using an automated hematology analyzer. Adjusted odds ratios (AORs) and 95% confidence intervals (CIs) were analyzed using multiple logistic regression model. The synergistic effect was analyzed using additive interaction for logistic regression. Physical inactive people exposed to SHS exhibited a synergistically increased 7.78-fold risk of T2DM compared with people who were not exposed to SHS and who were physically active. SHS is significantly correlated with a high NLR, WBCs and has a synergistic effect with physical inactivity on increasing susceptibility to T2DM.
Publisher: SAGE Publications
Date: 11-05-2020
Abstract: Physical inactivity and Type 2 diabetes mellitus (T2DM)–associated inflammatory biomarkers are correlated with poor quality of life (QoL). However, no study has investigated the synergistic effect of physical activity (PA) and lower neutrophil–lymphocyte ratio (NLR) on QoL. We examined the independent and synergistic effects of PA and inflammatory biomarkers on three domains of QoL in T2DM. This cross-sectional study included 294 patients with T2DM from community clinics in Indonesia. The 36-item Short Form Survey and a questionnaire about PA engagement were used to measure QoL and metabolic equivalent of task (MET)-hr/week, respectively. Inflammatory biomarkers were measured in fasting blood. Adjusted coefficients β and 95% confidence interval (CI) were estimated using multiple linear regression. The synergistic effect was analyzed using additive interaction for linear regression. Patients with PA ≥ 7.5 MET-hr/week exhibited significantly higher total QoL (β = 8.41, 95% CI = [6.04, 10.78]) and physical component score (PCS β = 13.90, 95% CI = [10.52, 17.29]) than those with PA 7.5 MET-hr/week. Patients with NLR 1.940 had significantly higher total QoL (β = 4.76, 95% CI = [3.41, 6.11]), mental component score (MCS β = 2.62, 95% CI = [0.75, 4.49]), and PCS (β = 6.89, 95% CI = [4.97, 8.82]) than patients with NLR ≥ 1.940. PA ≥ 7.5 MET-hr/week and NLR 1.940 exhibited a synergistic effect on total QoL, MCS, and PCS. High PA level and low NLR had a positive synergistic effect on QoL among patients with T2DM.
No related grants have been discovered for Yohanes Andy Rias.