ORCID Profile
0000-0002-1424-7528
Current Organisations
Monash University
,
University of Michigan
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Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8TB01979G
Abstract: Controlling the initial contact angle of biological sessile drops to advance the study and applications of their desiccated cracking patterns.
Publisher: American Chemical Society (ACS)
Date: 04-12-2019
Abstract: Transparent liquid marbles coated with hydrophobic silica nanoparticles were used as micro-bioreactors for embryonic stem cell (ESC) culturing. The high transparency of silica liquid marbles enables real-time and in situ monitoring of embryonic body (EB) formation and differentiation. The experimental result shows that ESCs can aggregate with each other close to the bottom of the liquid marble and form EBs, while remaining suspended in the culture media. The differentiation of the suspending EBs into contractile cardiomyocytes has been demonstrated inside the transparent liquid marbles, which enable the in situ microscopic observation. It was also found, through comparison, that ESCs in a bare sessile drop placed on a superhydrophobic substrate tend to anchor onto the substrate and then differentiate following the normal way of cell spreading, i.e., withdrawal from the cell cycle, fusion with nascent myotubes, and final differentiation into cardiomyocytes. In contrast, liquid marble particle shells weaken the adhesion of spherical EBs to the substrate, encouraging them to differentiate in suspension into cardiomyocytes, without anchoring. The results of this study highlight the promising performance of liquid marbles as "one-pot" micro-bioreactors for EB formation and differentiation.
Publisher: MDPI AG
Date: 22-07-2022
DOI: 10.3390/IJMS23158055
Abstract: Great efforts have been made to separate micro/nanoparticles in small-volume specimens, but it is a challenge to achieve the simple, maneuverable and low-cost separation of sub-microliter suspension with large separation distances. By simply adding trace amounts of cations (Mg2+/Ca2+/Na+), we experimentally achieved the size-dependent spontaneous separation of colloidal particles in an evaporating droplet with a volume down to 0.2 μL. The separation distance was at a millimeter level, benefiting the subsequent processing of the specimen. Within only three separating cycles, the mass ratio between particles with diameters of 1.0 μm and 0.1 μm can be effectively increased to 13 times of its initial value. A theoretical analysis indicates that this spontaneous separation is attributed to the size-dependent adsorption between the colloidal particles and the aromatic substrate due to the strong hydrated cation-π interactions.
Publisher: American Chemical Society (ACS)
Date: 11-07-2017
DOI: 10.1021/ACSSENSORS.7B00403
Abstract: Surface-enhanced Raman scattering (SERS) has the theoretical possibility of detecting chemicals at the single molecular level. This potential is frequently limited, however, by the critical requirements of the surface morphology and mechanical stability of SERS substrates. In this paper, we report a new method for fabricating a SERS substrate with a significantly improved mechanical stability and analytical sensitivity, using cellulose nanofibers (CNFs) and gold nanoparticles (AuNPs). We constructed a uniformly CNFs-textured substrate on a glass surface by means of suppressing the "coffee ring" effect of the CNF sessile drop and then introduced an AuNP suspension onto the CNFs-textured substrate by taking advantage of the "coffee ring" effect. A widened detection zone is formed by AuNPs on the CNFs-textured glass, producing a stable SERS substrate for trace analysis and chemical identification. Microscopic and spectroscopic characterizations of the CNF-AuNPs SERS substrate show that the CNFs enhance the stability of both the AuNP clusters and the SERS activity. The CNF-AuNPs SERS substrate is significantly more stable and sensitive than the SERS substrate fabricated by directly depositing the AuNP suspension on a smooth glass surface.
Publisher: Elsevier BV
Date: 03-2020
DOI: 10.1016/J.JCIS.2019.11.093
Abstract: Cellulose nanofibers (CNF) are promising nanomaterials for functional inks and printed sensors, although the potential applications are currently limited by the available functionalization methods. This work outlines a convenient method to grow a novel and highly conductive network of single-crystalline gold nanowires (AuNW) on CNF for use in conductive inks and printed sensors. The CNF are able to reduce Au (III) precursors to Au (0) monomers and generate nucleation sites for the subsequent monomer-by-monomer growth of Au nanocrystals sodium citrate is used to control the reduction kinetics and the crystal growth. The growth of these AuNW/CNF materials is a three-step process of redox reaction, isotropic nucleation and anisotropic crystallization: the morphology and crystal structure of Au nanocrystals on CNF can be controlled by adjusting the reaction temperature and concentrations of citrate and CNF. The AuNW/CNF materials obtained have been formulated into highly conductive and atmospherically stable inks for use in either directly writing or screen printing. We have demonstrated AuNW/CNF-printed sensors with highly controllable electrical conductivity as well as excellent stability against rinsing and immersion by water and ethanol.
Publisher: American Chemical Society (ACS)
Date: 17-05-2019
DOI: 10.1021/ACSSENSORS.9B00618
Abstract: The renewed interest in plasma desiccation patterns focuses on the potential of these patterns to be developed into a platform of low-cost and facile diagnostic methods to interpret health conditions of donors. During desiccation, several physical mechanisms are simultaneously acting on the plasma sessile drop these include material redistribution, buildup/release of local internal stresses, protein aggregation, and salt crystallization. After desiccation, cracking patterns and "superimposed" crystal-like patterns are formed. It has been reported that these characteristic patterns were influenced by changes in plasma compositions caused by diseases. Potential applications of these patterns in diagnosis are, however, limited by our understanding of formation mechanisms of cracking patterns and chemical compositions of crystal-like patterns. To address these limitations, this research studied morphologies of desiccated plasma patterns and the influence of sodium chloride to the pattern formation at both macroscopic and microscopic levels. Experimental results show that cracking patterns of plasma from healthy adults form throughout the desiccated deposit propagation directions of cracks are found to have correlations to local dominant stresses, which are governed by the development of gelation. Crystal-like patterns are located in the drop center, which are caused by the heterogeneous distribution of macromolecular proteins and sodium chloride within the plasma sessile drop during desiccation these patterns are influenced by the concentration of sodium chloride. With the increase of the concentration of sodium chloride, the distribution area of crystal-like patterns enlarges whereas, the number of cracks decreases.
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7TB02290E
Abstract: Formation mechanisms of cracking patterns in different regions of a desiccation blood sessile drop.
Publisher: Elsevier BV
Date: 09-2023
Publisher: Wiley
Date: 07-06-2019
Publisher: SAGE Publications
Date: 05-02-2019
Abstract: In this paper, we aim to study the effects of artificial sweat components on the photo-fading of reactive dyes on cotton fabrics. Two standards of artificial perspiration were tested according to the Japanese Industrial Standard (JIS L 0888 standard) and the Association for Textile Technical Study (ATTS standard), respectively. The light and perspiration stability of reactive dyes was characterized using the color difference value (DE). Standard orthogonal experiments were designed to study the influences of each artificial sweat component and the interaction between these components on the photo-fading reaction of the selected reactive dyes. The results indicated that L-histidine monohydrochloride monohydrate (0.5 g/L) was the dominant influencing factor on the light and perspiration stability of the reactive dyes exposing under both standards of artificial perspiration. In the JIS L 0888 standard, sodium chloride (5.0 g/L) played the significant role in the photo-fading reaction of the reactive dyes, while the influences caused by other components could be neglected. In the ATTS standard, sodium chloride (5.0 g/L), DL-aspartic acid (0.5 g/L) and glucose (5.0 g/L) aggravated the photo-fading of the selected reactive dyes.
No related grants have been discovered for Ruoyang Chen.