ORCID Profile
0000-0002-8243-2872
Current Organisation
RMIT University
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Colloid and Surface Chemistry | Nanomaterials | Optical Properties of Materials | Nanotechnology | Physical Chemistry (Incl. Structural)
Expanding Knowledge in the Chemical Sciences | Energy Conservation and Efficiency not elsewhere classified | Immune System and Allergy | Expanding Knowledge in Technology |
Publisher: World Scientific Pub Co Pte Lt
Date: 10-2010
DOI: 10.1142/S1793545810001155
Abstract: In this paper, amino capped CdSe/ZnS quantum dots (QDs) were immobilized on the 11-mercaptoundecanoic acid (MUA) self-assembled Au surface (SAM/Au) by 1-ethyl-3-(3-dimethyl-aminopropyl) carbodiimide hydrochloride (EDC). Atomic force microscopy (AFM), fluorescence imaging and electrochemistry were employed to characterize the surface. The results showed that CdSe/ZnS QDs were immobilized on the surface of SAM/Au successfully. Based on this method, the fluorescence of the QDs on the SAM/Au was monitored on-line.
Publisher: American Chemical Society (ACS)
Date: 03-01-2018
DOI: 10.1021/JACS.7B10694
Abstract: Mesoporous solids have been widely used in various biomedical areas such as drug delivery and tumor therapy. Although deformability has been recognized as a prime important characteristic influencing cellular uptake, the synthesis of deformable mesoporous solids is still a great challenge. Herein, deformable thioether-, benzene-, and ethane-bridged hollow periodic mesoporous organosilica (HPMO) nanocapsules have successfully been synthesized for the first time by a preferential etching approach. The prepared HPMO nanocapsules possess uniform diameters (240-310 nm), high surface areas (up to 878 m
Publisher: American Chemical Society (ACS)
Date: 30-12-2008
DOI: 10.1021/NL803459B
Abstract: We report the first observation of electrogenerated chemiluminescence (ECL) from PbS quantum dots (QDs). Different ECL intensities are observed for different ligands used to passivate the QDs, which indicates that ECL is sensitive to surface chemistry, with the potential to serve as a powerful probe of surface states and charge transfer dynamics in QDs. In particular, passivation of the QD surfaces with trioctylphosphine (TOP) increases ECL intensity by 3 orders of magnitude when compared to passivation with oleic acid alone. The observed overlap of the ECL and photoluminescence spectra suggests a significant reduction of deep surface trap states from the QDs passivated with TOP.
Publisher: American Chemical Society (ACS)
Date: 27-03-2018
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C7CP06861A
Abstract: Growth of femtoliter droplets on the top of a microlens is in a constant contact area mode. Droplets with finely tuneable volume may be converted to composite microlens arrays with desirable optical properties.
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8CP02353K
Abstract: Coupled effects from droplet formation and the local flow dramatically enhanced the droplet growth on a microfiber in flow.
Publisher: Wiley
Date: 09-01-2023
Abstract: Herein, we report, for the first time, a unique stiffness‐transformable manganese oxide hybridized mesoporous organosilica nanoplatform (MMON) for enhancing tumor therapeutic efficacy. The prepared MMONs had a quasi‐spherical morphology and were completely transformed into soft bowl‐like nanocapsules in the simulated tumor microenvironment through the breakage of Mn−O bonds, which decreased their Young's modulus from 165.7 to 84.5 MPa. Due to their unique stiffness transformation properties, the MMONs had reduced macrophage internalization, improved tumor cell uptake, and enhanced penetration of multicellular spheroids. In addition, in vivo experiments showed that the MMONs displayed a 3.79‐ and 2.90‐fold decrease in non‐specific liver distribution and a 2.87‐ and 1.83‐fold increase in tumor accumulation compared to their soft and stiff counterparts, respectively. Furthermore, chlorin e6 (Ce6) modified MMONs had significantly improved photodynamic therapeutic effect.
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D2BM01701F
Abstract: Schematic illustration of the elasticity of MONs-HA that regulates in vitro cellular uptake, in vivo blood circulation, and tumor accumulation.
Publisher: Proceedings of the National Academy of Sciences
Date: 09-07-2015
Abstract: Solvent exchange is a generally used approach for producing many nanoscale droplets on an immersed substrate. In this process, a good solvent is displaced by a poor solvent of oil, leading to oil nanodroplet nucleation and subsequent growth on the substrate. This work is, to our knowledge, the first attempt to quantitatively understand the relationship between the droplet size and the flow conditions during the solvent exchange, and to pave the way for the droplet size control. The experimental results show that the droplet volume increases with increasing Peclet number of the flow as ∝ P e 3 / 4 , in good agreement with our theoretical analysis. We also reveal that the buoyancy effects contribute to the formation of bigger and less homogeneously distributed droplets in less-narrow channels.
Publisher: Springer Science and Business Media LLC
Date: 30-06-2020
DOI: 10.1007/S40820-020-00465-7
Abstract: To date, the ability of nanoplatforms to achieve excellent therapeutic responses is hindered by short blood circulation and limited tumor accumulation enetration. Herein, a soft mesoporous organosilica nanoplatform modified with hyaluronic acid and cyanine 5.5 are prepared, denoted SMONs-HA-Cy5.5, and comparative studies between SMONs-HA-Cy5.5 (24.2 MPa) and stiff counterparts (79.2 MPa) are conducted. Results indicate that, apart from exhibiting a twofold increase in tumor cellular uptake, the soft nanoplatforms also display a remarkable pharmacokinetic advantage, resulting in considerably improved tumor accumulation. Moreover, SMONs-HA-Cy5.5 exhibits a significantly higher tumor penetration, achieving 30-μm deeper tissue permeability in multicellular spheroids relative to the stiff counterparts. Results further reveal that the soft nanoplatforms have an easier extravasation from the tumor vessels, diffuse farther in the dense extracellular matrix, and reach deeper tumor tissues compared to the stiff ones. Specifically, the soft nanoplatforms generate a 16-fold improvement (43 vs. 2.72 μm) in diffusion distance in tumor parenchyma. Based on the significantly improved blood circulation and tumor accumulation enetration, a soft therapeutic nanoplatform is constructed by loading photosensitizer chlorin e6 in SMONs-HA-Cy5.5. The resulting nanoplatform exhibits considerably higher therapeutic efficacy on tumors compared to the stiff ones.
Publisher: American Chemical Society (ACS)
Date: 11-03-2021
Publisher: Wiley
Date: 20-09-2018
Publisher: Elsevier BV
Date: 05-2019
DOI: 10.1016/J.JCIS.2019.02.046
Abstract: Microscopic droplets integrating multiple functionalities are essential in the microcompartmentalized related reaction and applications. Solvent exchange is a simple approach for producing femtoliter surface droplets by the transit oversaturation created at the mixing front of a solution by a poor solvent. But it remains challenging to control the compositions in nanodroplets. Our hypothesis is the new liquid component can be added to the pre-formed surface droplets at certain ratios controlled by solvent exchange. In this work we investigate the growth of the droplets during addition of a new component by solvent exchange. Two-component droplets were formed on a microdomain patterned substrate as highly ordered arrays. The physical and chemical parameters that control droplet composition and a possible application of the binary droplet arrays were presented in this work. The added amount of the second component in the binary droplet can be quantitatively controlled by the solution and flow conditions. The theoretical prediction of the component ratio based on the droplet diffusive growth dynamics mode shows a good agreement with the experimental results. The results show that the solvent exchange on the surface with pre-formed droplets provides a highly efficient method to tune the droplet compositions to desired ratio. The unique feature of this approach enables a gradient structure of droplet composition over the surface, demonstrated by an application of different microlens performance on a surface.
Publisher: MDPI AG
Date: 02-10-2019
DOI: 10.3390/MOLECULES24193569
Abstract: A series of fluorescent coumarin derivatives 2a–e were systematically designed, synthesized and studied for their Cu2+ sensing performance in aqueous media. The sensitivities and selectivities of the on-to-off fluorescent Cu2+ sensing signal were in direct correlation with the relative arrangements of the heteroatoms within the coordinating moieties of these coumarins. Probes 2b and 2d exhibited Cu2+ concentration dependent and selective fluorescence quenching, with linear ranges of 0–80 μM and 0–10 μM, and limits of detection of 0.14 μM and 0.38 μM, respectively. Structural changes of 2b upon Cu2+ coordination were followed by fluorescence titration, attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), mass spectrometry, and single crystal X-ray diffraction on the isolated Cu2+-coumarin complex. The results revealed a 1:1 stoichiometry between 2b and Cu2+, and that the essential structural features for Cu2+-selective coordination are the coumarin C=O and a three-bond distance between the amide NH and heterocyclic N. Probe 2b was also used to determine copper (II) levels in aqueous soil extracts, with recovery rates over 80% when compared to the standard soil analysis method: inductively coupled plasma-mass spectrometry (ICP-MS).
Publisher: Springer Science and Business Media LLC
Date: 11-06-2010
DOI: 10.1007/S11033-010-0190-3
Abstract: A simple, controllable and effective s le preparation method was established for atomic force microscopy (AFM) imaging of in idual DNA molecules in aqueous solution. Firstly, magnesium ion (Mg(2+)) at a concentration of 5.0-10.0 mM as a positively charged bridge was transferred onto mica to immobilize DNA molecules. Then Mg(2+)-modified mica was used to investigate DNA molecules in any buffer without magnesium ion by AFM. AFM images demonstrated that DNA molecules can be successfully observed in solution with good resolution, reproducibility, and stability. Further, this DNA s le preparation method makes AFM successful to investigate DNA molecular interaction in situ and DNA/chitosan complex in gene delivery.
Publisher: American Chemical Society (ACS)
Date: 03-07-2019
Abstract: Microlens arrays are key elements for light management in optoelectronic devices. The recent advancement in the wearable intelligent electronics has driven the development of flexible microlenses. In this work, we show a controllable and scalable surface-droplet-based strategy to create unconventional flexible polymer microlens arrays. The technique is underpinned by the morphological transition of femtoliter liquid on the surface of a microlens surrounded by a planar area. We found that the droplet liquid wetted the rim of the microlens first and gradually moved upward to the microlens surface with an increase in the liquid volume. The morphology evolution of the droplet is in good agreement with the predication from our simulations based on the interfacial energy minimization under the condition of the pinned boundary. The shape of the droplet on the microlens is well controlled by the droplet volume, aspect ratio of the microlens, and the interfacial energy of the droplets on the microlens. As a result, the obtained structures of one microlens partially covered by a droplet can be produced in arrays over a large scale, serving as templates for fabricating transparent polymer double microlens arrays for improved light emission from the optoelectronic device.
Publisher: American Chemical Society (ACS)
Date: 24-07-2014
DOI: 10.1021/AC502405P
Abstract: Recently, research on carbon nanodots (C-dots), a new type of luminescent nanoparticles with superior optical properties, biocompatibility, and low cost, has been focused on exploring novel properties and structure-related mechanisms to extend their scope. Herein, electrochemiluminescence, a surface-sensitive tool, is used to probe the unrevealed property of carbon nanodots which is characterized by surface oxygen-containing groups. Together with chemiluminescence, carbon nanodots as the coreactants for the anodic electrochemiluminescence of Ru(bpy)3(2+) are demonstrated for the first time. During the anodic scan, the benzylic alcohol units on the C-dots surface are oxidized "homogeneously" by electrogenerated-Ru(bpy)3(3+) to form reductive radical intermediate, which further reduce Ru(bpy)3(3+) into Ru(bpy)3(2+)* that produces a strong ECL emission. This work has provided an insight into the ECL mechanism of the C-dots-involved system, which will be beneficial for in-depth understanding of some peculiar phenomena of C-dots, such as photocatalytic activity and redox properties. Moreover, because of the features of C-dots, the ECL system of Ru(bpy)3(2+)/C-dots is more promising in the bioanalysis.
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C5NR00842E
Abstract: An efficient edge-functionalization strategy with high specificity was employed to study the effects of conjugated structures on photoluminescence (PL) properties of graphene quantum dots (GQDs). Both the experimental results and density functional theory (DFT)-based calculations suggested the mechanism for conjugated structures in GQDs to tune the band gap of GQDs.
Publisher: American Chemical Society (ACS)
Date: 08-03-2016
DOI: 10.1021/ACS.JPCLETT.6B00099
Abstract: Femtoliter droplet arrays on immersed substrates are essential elements in a broad range of advanced droplet-based technologies, such as light manipulation, sensing, and high throughput diagnosis. Solvent exchange is a bottom-up approach for producing those droplets from a pulse of oil oversaturation when a good solvent of the droplet liquid is displaced by a poor solvent. The position and arrangement of the droplets are regulated by chemical micropatterns on the substrate. Here we show experimentally and theoretically that the growth modes of droplets confined in planar micropatterns on the surface can be manipulated through the laminar flow of the solvent exchange. The control parameters are the area size of the micropatterns and the flow rate, and the observables are the contact angle and the final droplet volume. For a given pattern size, the Peclet number of the flow determines whether the growing droplets switch from an initial constant contact angle mode to a subsequent constant contact radius mode. Good agreement is achieved between the experimental results and our theoretical model that describes the dependence of the final droplet size on Pe.
Publisher: Wiley
Date: 04-08-2023
Abstract: Granular microporous hydrogels are emerging as effective biomaterial scaffolds for tissue engineering due to their improved characteristics compared to traditional nanoporous hydrogels, which better promote cell viability, cell migration, cellular/tissue infiltration, and tissue regeneration. Recent advances have resulted in the development of granular hydrogels made of non‐spherical microgels, which compared to those made of spherical microgels have higher macroporosity, more stable mechanical properties, and better ability to guide the alignment and differentiation of cells in anisotropic tissue. The development of these hydrogels as an emerging research area is attracting increasing interest in regenerative medicine. This review first summarizes the fabrication techniques available for non‐spherical microgels with different aspect‐ratios. Then, it introduces the development of granular microporous hydrogels made of non‐spherical microgels, their physicochemical characteristics, and their applications in tissue regeneration. The limitations and future outlook of research on microporous granular hydrogels are also critically discussed.
Publisher: Wiley
Date: 06-12-2011
Abstract: The size of C-nanodots can be electrochemically tuned by changing the applied potential during their preparation. The higher the applied potential, the smaller the resulting C-nanodots. Moreover, the surface oxidation degree of the C-nanodots can also be electrochemically tuned. The red-shift of emission independent of the size provides an insight into the luminescence mechanism of C-nanodots.
Publisher: Wiley
Date: 04-2022
Publisher: American Chemical Society (ACS)
Date: 30-09-2011
DOI: 10.1021/AC201631B
Abstract: We presented a new aptamer biosensor for thrombin in this work, which was based on fluorescence resonance energy transfer (FRET) from upconverting phosphors (UCPs) to carbon nanoparticles (CNPs). The poly(acrylic acid) (PAA) functionalized UCPs were covalently tagged with a thrombin aptamer (5'-NH(2)- GGTTGGTGTGGTTGG-3'), which bound to the surface of CNPs through π-π stacking interaction. As a result, the energy donor and acceptor were taken into close proximity, leading to the quenching of fluorescence of UCPs. A maximum fluorescence quenching rate of 89% was acquired under optimized conditions. In the presence of thrombin, which induced the aptamer to form quadruplex structure, the π-π interaction was weakened, and thus, the acceptor was separated from the donor blocking the FRET process. The fluorescence of UCPs was therefore restored in a thrombin concentration-dependent manner, which built the foundation of thrombin quantification. The sensor provided a linear range from 0.5 to 20 nM for thrombin with a detection limit of 0.18 nM in an aqueous buffer. The same linear range was obtained in spiked human serum s les with a slightly higher detection limit (0.25 nM), demonstrating high robustness of the sensor in a complex biological s le matrix. As a practical application, the sensor was used to monitor thrombin level in human plasma with satisfactory results obtained. This is the first time that UCPs and CNPs were employed as a donor-acceptor pair to construct FRET-based biosensors, which utilized both the photophysical merits of UCPs and the superquenching ability of CNPs and thus afforded favorable analytical performances. This work also opened the opportunity to develop biosensors for other targets using this UCPs-CNPs system.
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9BM01559K
Abstract: Virus-mimicking mesoporous organosilica nanocapsules possess enhanced cellular uptake and tumor penetration.
Publisher: Elsevier BV
Date: 08-2019
DOI: 10.1016/J.JCIS.2019.04.086
Abstract: Soft nanoparticles have attracted increasing attention in biomedical fields because of their unique biological behaviors such as long circulation and high cellular uptake. However, previously reported soft nanoparticles are generally spherical or torispherical in shape, and non-spherical soft nanoparticles are rarely reported because of the shape is thermodynamically unstable for typical soft materials (e.g., liposomes and micelles). Herein, soft mesoporous organosilica nanorods with gold plasmonic core protected with poly-ethylene imine (GNR@SMON/PEI) have been successfully synthesized, for the first time, by a dispersive-protection etching method, in which rod-like solid mesoporous organosilicas with gold nanorod are firstly shielded with PEI (GNR@MON/PEI) and then etched with aqueous NaOH solution. The prepared GNR@SMON/PEI inherits the rod morphology of the mother particle, showing wrinkled morphology and excellent dispersity thanks to the dispersive-protection effect of PEI. In addition, the GNR@SMON/PEI possesses a uniform size (174 × 105 nm), well-defined mesopores (3.9 nm), high surface area (355 m
Publisher: Springer Science and Business Media LLC
Date: 21-12-2015
DOI: 10.1038/SREP18515
Abstract: Bubble formation from plasmonic heating of nanostructures is of great interest in many applications. In this work, we study experimentally the intrinsic effects of the number of three-dimensional plasmonic nanostructures on the dynamics of microbubbles, largely decoupled from the effects of dissolved air. The formation and dissolution of microbubbles is observed on exciting groups of 1, 4 and 9 nanopillars. Our results show that the power threshold for the bubble formation depends on the number density of the nanopillars in highly-ordered arrays. In the degassed water, both the growth rate and the maximal radius of the plasmonic microbubbles increase with an increase of the illuminated pillar number, due to the heat balance between the heat loss across the bubble and the collective heating generated from the nanopillars. Interestingly, our results show that the bubble dissolution is affected by the spatial arrangement of the underlying nanopillars, due to the pinning effect on the bubble boundary. The bubbles on nanopillar arrays dissolve in a jumping mode with step-wise features on the dissolution curves, prior to a smooth dissolution phase for the bubble pinned by a single pillar. The insight from this work may facilitate the design of nanostructures for efficient energy conversion.
Publisher: Wiley
Date: 14-07-2022
Abstract: Wide bandgap semiconducting oxides are emerging as potential 2D materials for transparent electronics and optoelectronics. This fuels the quest for discovering new 2D metal oxides with ultrahigh transparency and high mobility. While the former can be achieved by reducing the thickness of oxide films to only a few nanometers, the latter is more commonly realized by intentional doping. This article reports a one‐step synthesis of few‐unit‐cell‐thick and laterally large antimony‐doped indium oxide (IAO). The doping process occurs spontaneously when the oxide is grown on the surface of a molten Sb–In alloy and 2D IAO nanosheets can be easily printed onto desired substrates. With thicknesses at the atomic scale, these materials exhibit excellent transparency exceeding 98% across the visible and near‐infrared range. Field‐effect transistors based on low‐doped IAO nanosheets reveal a high electron mobility of ≈40 cm 2 V −1 s −1 . Additionally, a notable photoresponse is observed in 2D IAO‐based photodetectors under ultraviolet (UV) radiation. Photoresponsivities of low‐doped and highly doped IAO at a wavelength of 285 nm are found to be 1.2 × 10 3 and 0.7 × 10 3 A W −1 , respectively, identifying these materials as promising candidates for the fabrication of high‐performance optoelectronics in the UV region.
Publisher: Springer Science and Business Media LLC
Date: 31-05-2022
DOI: 10.1007/S11051-022-05492-6
Abstract: A SiO 2 -coumarin nanohybrid was investigated for its Cu(II) sensing performance in aqueous media, and in comparison with the Cu(II)-selective coumarin used alone. Fluorescence of both coumarin itself and the nanohybrid, λ ex / λ em 435/481 nm, was selectively quenched by Cu(II) when tested against a range of multivalent cations. The nanohybrid had enhanced Cu(II) sensing properties when compared to the coumarin including (i) improved limit of detection from μM-level (0.48 μM) of Cu(II) using coumarin alone to nM-level (0.033 μM) and (ii) an extended linear detection range of 0.033–260 μM (0.0005–4.1 mg/mL) Cu(II) compared to 0.48–55 μM for the coumarin itself. The lower limit of detection and extended range were achieved with a smaller amount of coumarin and no traces of organic solvents used to help coumarin dissolution. Characterization suggested that under applied test conditions at pH = 5, SiO 2 nanoparticles with negative surface charges adsorbed coumarin and then (when present) Cu(II) ions. The SiO 2 -coumarin nanohybrid was then applied for the determination of Cu(II) levels in aqueous soil extracts reaching over 94% recovery rates when used against the standard soil analysis method by inductively coupled plasma mass spectrometry (ICP-MS). Graphical Abstract
Publisher: Elsevier BV
Date: 04-2018
Publisher: Elsevier BV
Date: 10-2021
Publisher: Wiley
Date: 11-03-2016
Abstract: Ultrabright carbon nanodots-hybridized silica nanospheres (CSNs) are synthesized through the Stöber process of silane functionalized C-dots. The fluorescence of carbon nanodots is converged intensely. A CSN is about 3800 times brighter than a single-carbon nanodot. Along with their high brightness and low cytotoxicity, CSNs also indicate their potential application in cellular labeling.
Publisher: IEEE
Date: 05-2008
Publisher: American Chemical Society (ACS)
Date: 14-06-2019
DOI: 10.1021/ACS.JPCLETT.9B01339
Abstract: The functional groups and π-electron system of carbon dots (C-dots) were carefully controlled by several innovative chemical methods, without any changes in size, to unravel the relationship between the surface structure and photoluminescence (PL). The results of experiments and theoretical calculations reveal that the PL of C-dots is related to the surface state. The energy gap is determined by the coupling of the π-electron system and carbonyl group, and the quantum yield (QY) is dependent on the carbonyl group. The carbonyl group is the main factor increasing the ratio of nonradiation to radiation recombination, thereby leading to the low QY of C-dots. This work provides a strategy for effectively tuning the structure of C-dots, giving rise to the tunable PL emission wavelength and highly desirable QY, which enables us to further unravel the PL mechanism.
Publisher: Informa UK Limited
Date: 18-02-2019
Publisher: Wiley
Date: 14-07-2015
Publisher: American Chemical Society (ACS)
Date: 18-07-2018
DOI: 10.1021/ACS.LANGMUIR.8B01252
Abstract: The crystallization of oil droplets is critical in the processing and storage of lipid-based food and pharmaceutical products. Arrays of femtoliter droplets on a surface offer a unique opportunity to study surfactant-free colloidlike systems. In this work, the crystal growth process in these confined droplets was followed by cooling a model lipid (trimyristin) from a liquid state utilizing synchrotron small-angle X-ray scattering (SAXS). The measurements by SAXS demonstrated a reduced crystallization rate and a greater degree of supercooling required to trigger lipid crystallization in droplets compared to those of bulk lipids. These results suggest that surface droplets crystallize in a stochastic manner. Interestingly, the crystallization rate is slower for larger femtoliter droplets, which may be explained by the onset of crystallization from the three-phase contact line. The larger surface nanodroplets exhibit a smaller ratio of droplet volume to the length of three-phase contact line and hence a slower crystallization rate.
Publisher: American Chemical Society (ACS)
Date: 03-03-2016
Abstract: With unique and tunable photoluminescence (PL) properties, carbon nanodots (CNDs) as a new class of optical tags have been extensively studied. Because of their merits of controllability and sensitivity to the surface of nanomaterials, electrochemical methods have already been adopted to study the intrinsic electronic structures of CNDs. In this review, we mainly deal with the electrochemical researches of CNDs, including preparation, PL mechanism, and biosensing.
Publisher: American Chemical Society (ACS)
Date: 11-10-2012
DOI: 10.1021/AC301835F
Abstract: The near-infrared (NIR) electrogenerated chemiluminescence (ECL) of water-dispersed Ag(2)Se quantum dots (QDs) with ultrasmall size was presented for the first time. The Ag(2)Se QDs have shown a strong and efficient cathodic ECL signal with K(2)S(2)O(8) as coreactant on the glassy carbon electrode (GCE) in aqueous solution. The ECL spectrum exhibited a peak at 695 nm, consistent with the peak in photoluminescence (PL) spectrum of the Ag(2)Se QDs solution, indicating that the Ag(2)Se QDs had no deep surface traps. Dopamine was chosen as a model analyte to study the potential of Ag(2)Se QDs in the ECL analytical application. The ECL signal of Ag(2)Se QDs can also be used for the detection of the dopamine concentration in the practical drug (dopamine hydrochloride injection) containing several adjuvants such as edetate disodium, sodium bisulfite, sodium chloride and so on. The Ag(2)Se QDs could be a promising candidate emitter of ECL biosensors in the future due to their fantastic features, such as ultrasmall size, low toxicity, good water solubility, and near infrared (NIR) fluorescent emission.
Publisher: S. Karger AG
Date: 2022
DOI: 10.1159/000521209
Abstract: b i Questions: /i /b What are the daily temporal patterns of movement behaviours (sedentary time, light-intensity physical activity, and moderate-vigorous physical activity) in people with stroke? Do daily temporal patterns of sedentary time differ (a) between subgroups of people with different movement behaviour classifications and (b) over time during the first year after stroke? b i Design: /i /b This study represents secondary exploratory analyses from an observational, longitudinal cohort study ( i n /i = 197). b i Participants: /i /b This study included people with first-ever stroke recruited from 4 hospitals in the Netherlands. b i Outcome Measures: /i /b Movement behaviour was objectively measured using the Activ8 activity monitor within 3 weeks after hospital discharge and again at 6 and 12 months later. b i Results: /i /b Participants spent the least time sedentary in the morning with proportionally more sedentary time as the day progressed with maximal sedentary time seen in the evening hours. This pattern did not substantially change over time. i Sedentary prolongers /i spent significantly more absolute time sedentary for each hour of the day, but the daily temporal pattern of sedentary time did not differ between this group and either “ i sedentary movers /i ” or “ i sedentary exercisers /i .” b i Conclusion: /i /b People living at home after stroke are highly sedentary, particularly in the afternoons and evenings, and this pattern does not change during the first year after stroke. Clinicians should encourage people with stroke to find meaningful tasks to do during the day to reduce their sitting time. Researchers developing interventions to encourage people to sit less should include particular focus on the afternoon and evening time periods.
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2NR03415H
Abstract: C-dots loaded cubosome is green fluorescent for cell imaging.
Publisher: American Chemical Society (ACS)
Date: 31-08-2011
DOI: 10.1021/JP205419Z
Publisher: Elsevier BV
Date: 02-2008
Publisher: Springer Science and Business Media LLC
Date: 12-2007
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4SM02397H
Abstract: The dissolution dynamics of microscopic oil droplets (less than 1 μm in height, i.e. nanodroplets) on a hydrophobilized silicon surface in water was experimentally studied. The lateral diameter was monitored using confocal microscopy, whereas the contact angle was measured by (disruptive) droplet polymerisation of the droplet. In general, we observed the droplets to dissolve in a mixed mode, i.e., neither in the constant contact angle mode nor in the constant contact radius mode. This means that both the lateral diameter and the contact angle of the nanodroplets decrease during the dissolution process. On average, the dissolution rate is faster for droplets with larger initial size. Droplets with the same initial size can, however, possess different dissolution rates. We ascribe the non-universal dissolution rates to chemical and geometric surface heterogeneities (that lead to contact line pinning) and cooperative effects from the mass exchange among neighbouring droplets.
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C7LC01321C
Abstract: The dissolution of femtoliter droplet arrays on the wall of microfluidic channels is determined by coupled effects from the collective interaction of droplets and external flow conditions. Controlled droplet dissolution enables a novel approach for the fabrication of a multifocal lens array.
Publisher: Wiley
Date: 14-01-2015
Abstract: The photoluminescence of carbon nanodots (C-dots) can be tuned by changing their surface chemistry or size because the photoluminescence is a function of the surface-state electronic transitions. Increasing the degree of surface oxidation leads to a narrowing of the energy gap of the surface meanwhile, larger C-dots with an extensive π-electron system, which can couple with surface electronic states, can also lead to a narrowing of the energy gap of the surface states.
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2SM00557C
Abstract: The film, porous and granular nanostructures are generated from evaporating carbon dot-laden ternary droplets. Liquid–liquid phase separation during evaporation is unravelled as a critical role in the controlled self-assembly of carbon nanodots.
Publisher: Royal Society of Chemistry (RSC)
Date: 2012
DOI: 10.1039/C2JM30639E
Publisher: Elsevier BV
Date: 10-2021
Publisher: Elsevier BV
Date: 06-2009
DOI: 10.1016/J.BIOS.2009.03.005
Abstract: The performance of electrochemical sensor is related to the surface structure of electrode. Electrochemical treatment was often used to improve the performance of glassy carbon electrodes (GCEs) for the simplicity of operation. The densely compact oxide film formed on the surface of the electro-oxidized glassy carbon electrodes (GCEs-ox) could be changed to be porous by following electro-reduction of the GCEs-ox obtaining the totally reduced GCEs-ox (GCEs-re). The GCEs-re with a porous film exhibited high sensitivity in detecting epinephrine (EP) accompanying with poor stability and incapability of anti-interference from negatively charged ascorbic acid (AA) because both of AA and EP could permeate the porous film. Compared to the GCEs-re, the GCEs-ox with a densely compact film displayed relatively lower sensitivity but higher stability. To combine the advantages of both porous and densely compact oxide films, a partially reduced GCE-ox (GCE-ox-re) with an oxide film porous outer and densely compact inner was designed by controlling the electro-reduction time and potential, which will provide a new strategy for improving the performance of GCEs. The GCEs-ox-re exhibited high sensitivity, excellent stability and high selectivity in the detection of EP. In the presence of 0.1 mM AA, the anodic peak current of EP was directly proportional to its concentration in the range of 8.0x10(-9)-2.0x10(-7) M and EP as low as 2.0x10(-9) M could be detected.
Start Date: 2019
End Date: 2022
Funder: Australian Research Council
View Funded ActivityStart Date: 2017
End Date: 2019
Funder: Australian Research Council
View Funded ActivityStart Date: 05-2019
End Date: 12-2024
Amount: $352,473.00
Funder: Australian Research Council
View Funded ActivityStart Date: 06-2015
End Date: 12-2018
Amount: $276,433.00
Funder: Australian Research Council
View Funded Activity