Fabio Pesciaioli

Asymmetric Organocatalysis Accelerated via Self‐Assembled Minimal Structures

Publisher: Wiley

Date: 14-09-2021

DOI: 10.1002/EJOC.202101042

Abstract: Self‐assembling minimalistic peptides embedded with an organocatalytic moiety were designed. By controlling the formation of fibrils via external intervention, it was shown that the activation is accelerated when the organocatalyst is in its supramolecular state. The effect of the accelerated catalysis was demonstrated in a Michael benchmark reaction.

Cover Feature: Asymmetric Organocatalysis Accelerated via Self‐Assembled Minimal Structures (Eur. J. Org. Chem. 39/2021)

Publisher: Wiley

Date: 04-10-2021

DOI: 10.1002/EJOC.202101219

Enantioselective Cobalt(III)‐Catalyzed C−H Activation Enabled by Chiral Carboxylic Acid Cooperation

Publisher: Wiley

Date: 19-11-2018

DOI: 10.1002/ANIE.201808595

Abstract: The enantioselective cobalt(III)-catalyzed C-H alkylation was achieved through the design of a novel chiral acid. The cobalt(III)-catalyzed enantioselective C-H activation was characterized by high position-, regio- and enantio-control under exceedingly mild reaction conditions. Thereby, the robust cooperative cobalt(III) catalysis proved tolerant of valuable electrophilic functional groups, including hydroxyl, bromo, and iodo substituents. Mechanistic studies revealed a considerable additive effect on kinetics and on a negative non-linear-effect.

Rheinisch Westfälische Technische Hochschule Aachen RWTH Aachen Fakultät Für Mathematik Informatik Und Naturwissenschaften

Location: Germany

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Max-Planck-Institut Für Kohlenforschung

Location: Germany

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Università Degli Studi Dell'Aquila

Location: Italy

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University Of Goettingen

Location: Germany

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Università Degli Studi Di Pavia Dipartimento Di Chimica

Location: Italy

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Università Degli Studi Di Bologna

Location: Italy

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