ORCID Profile
0000-0001-9579-6889
Current Organisations
University of Adelaide
,
Queensland University of Technology
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Publisher: Elsevier BV
Date: 06-2020
Publisher: Elsevier BV
Date: 05-2020
Publisher: Informa UK Limited
Date: 03-2020
DOI: 10.2147/NSS.S239001
Publisher: Elsevier BV
Date: 08-2023
Publisher: Hindawi Limited
Date: 19-07-2022
DOI: 10.1155/2022/7071801
Abstract: Background. The role of sleep in childhood myopia has been a research focus however, the existing evidence is conflicting on sleep duration and timing, and as yet, no studies involve sleep consistency and chronotype. This study is done to make multiple-perspective analyses on the associations between sleep variables and myopia. Methods. A population-based cross-sectional study was conducted in Shanghai, China, which included 10,142 school-aged children (7–12 years old, 53.2% boys). The Chinese version of the Children’s Sleep Habits Questionnaire (CSHQ) was used to assess sleep variables. Propensity score matching was adopted to balance the difference of covariates between nonmyopic and myopic groups. Logistic regression models were implemented to examine the associations between sleep variables and myopia. Results. Sleep duration and timing, mainly during weekdays, were correlated with myopia in a dose-dependent pattern, in which longer sleep duration was associated with decreased risk of myopia (9-10 hours/day: odds ratio (OR) = 0.87 ≥10 hours/day: OR = 0.77 by comparison with hours/day) later bedtime (9 pm to 9:30 pm: OR = 1.46 9:30 pm to 10 pm: OR = 1.51 10 pm and after: OR = 2.08 by comparison with before 9 pm) and later wake-up time (7 am and after: OR = 1.36 by comparison with before 6:30 am) increased the risk (all P 0.05 ). Moreover, longer weekend catch-up sleep duration and intermediate and evening chronotype were positively correlated with myopia, while social jetlag was associated with a lower odds of myopia. All these findings were also similarly observed in the matching s le. Conclusions. Multiple dimensions of sleep were involved in childhood myopia. In addition to sleep duration and timing, sleep consistency and chronotype were also strictly related to myopia. More studies are needed to enrich the current evidence, thus further clarifying the association between sleep and childhood myopia.
Publisher: Springer Science and Business Media LLC
Date: 10-06-2021
DOI: 10.1007/S12519-021-00436-X
Abstract: Asthma has been a global problem, especially in children. We aim to evaluate the contemporary prevalence and influencing factors of asthma among children aged 3-7 years in Shanghai, China. A random s le of preschool children was included in this study. The International Study of Asthma and Allergies in Childhood questionnaire was adopted to assess the childhood asthma. Multivariable logistic regression models were used to evaluate the associations between independent variables and childhood asthma. Of 6389 preschool children who were invited to take part in this study, 6163 (response rate: 96.5%) completed the questionnaire and were included in the analysis. The overall prevalence of asthma was 14.6% which increased more than six folds from 2.1% in 1990. Being male, younger age, preterm delivery, being born in spring or autumn, being delivered by elective cesarean section without indication, miscarriage, high socioeconomic status, having allergy history, and exposure to passive smoking, latex paint, and dust were potential risk factors for childhood asthma. Spending more time outdoors (> 30 min/day), having indoor plants, and cleaning rooms more frequently were potential protective factors. The prevalence of childhood asthma in Shanghai has increased dramatically during the past three decades. The findings about risk and protective factors of childhood asthma could be used to develop appropriate strategies to prevent and control childhood asthma in Shanghai and in other similar metropolitan cities.
Publisher: Elsevier BV
Date: 08-2023
Publisher: Springer Science and Business Media LLC
Date: 06-02-2021
DOI: 10.1186/S12931-021-01644-9
Abstract: Childhood asthma and allergic diseases are a significant global problem. There are inconsistent findings on the associations of delivery mode, the number of children in the household and breastfeeding with childhood asthma and allergic diseases. We assessed these associations and examined whether breastfeeding modified the effects of neonatal and familial risk factors on childhood asthma and allergic diseases. A population-based cross-sectional study was conducted in Shanghai, China. A total of 17 primary schools were randomly selected from 13 districts of Shanghai in this study. The International Study of Asthma and Allergies in Childhood questionnaire was adopted to assess the childhood asthma and allergic diseases. Multivariable logistic regression models were used to evaluate the associations between neonatal and familial factors and childhood asthma and allergic diseases, and to examine the modification effects of breastfeeding on the associations assessed. Of 10,464 primary school children aged 6–11 years, the overall prevalence of childhood asthma, allergic rhinitis, urticaria, food allergy and drug allergy was 13.9, 22.7, 15.3, 8.1 and 4.6%, respectively. Male sex, high socioeconomic status, cesarean section delivery, only one child in the household and having family history of allergy were associated with increased odds ratio (OR) of childhood asthma and allergic diseases while longer breastfeeding duration ( 6 months) was inversely associated with these diseases. Longer breastfeeding duration also attenuated the OR of neonatal and familial risk factors on childhood asthma and allergic diseases. For instance, the adjusted OR of childhood asthma in the group of vaginal delivery and breastfeeding duration 6 months was lowest (0.78, 95% confidence interval: 0.66, 0.92). Longer breastfeeding duration was inversely associated with childhood asthma and allergic diseases, and also reduced the OR of neonatal and familial risk factors on these diseases. Giving the prevalence of childhood asthma and allergic diseases is rapidly rising across the globe, these findings may have important clinical and public health implications.
Publisher: Elsevier BV
Date: 02-2019
DOI: 10.1016/J.SCITOTENV.2018.08.332
Abstract: Few data are available on the health impacts of heatwaves in China, and in particular, the heatwave definition and vulnerable populations remain to be identified. We collected data on daily maximum temperature and mortality from 31 Chinese capital cities during 2007-2013. A Poisson regression model allowing for over-dispersion was applied to estimate the short-term effects of heatwaves on mortality in hot season (May-September). 15 heatwave definitions combining five heat thresholds (90.0th, 92.5th, 95th, 97.5th and 99th percentiles of daily maximum temperature) and three durations (≥2, ≥3 and ≥4 days) were compared. The pooled effects were then computed using random effect meta-analysis based on the residual maximum likelihood estimation. Effect modification of heatwave-mortality association by in idual-level characteristics was tested using a stratified analysis. Potential effect modification by city-level characteristics was examined by meta-regression analysis. Totally, 259 million permanent residents were covered and 4,481,090 non-accidental deaths occurred during the study period. Generally, the magnitude of heatwave impacts increased by intensities and durations of the heatwaves. Heatwave definition using daily maximum temperature ≥ 92.5th percentile with duration ≥3 days produced the best model fit. The pooled relative risks of heatwaves on non-accidental mortality at lag 0, lag 0-2 and lag 0-10 days were 1.06 (95%CI: 1.03-1.09), 1.09 (1.05-1.13) and 1.10 (1.05-1.15), respectively. Compared with non-accidental mortality, higher effect estimates of heatwaves were observed among deaths from ischemic heart diseases, stroke and respiratory diseases, although the differences were not statistically significant. Females, those ≥75 years old and the illiterates were more vulnerable to heatwaves. Cities with higher concentrations of PM
Publisher: Research Square Platform LLC
Date: 17-11-2020
DOI: 10.21203/RS.3.RS-105228/V1
Abstract: Background : Childhood asthma and allergic diseases are a significant global problem. There are inconsistent findings on the associations of delivery mode, the number of children in the household and breastfeeding with childhood asthma and allergic diseases. We assessed these associations and examined whether breastfeeding modified the effects of neonatal and familiar risk factors on childhood asthma and allergic diseases. Methods : A population-based cross-sectional study was conducted in Shanghai, China. A total of 17 primary schools were randomly selected from 13 districts of Shanghai in this study. The International Study of Asthma and Allergies in Childhood questionnaire was adopted to assess the childhood asthma and allergic diseases. Multivariable logistic regression models were used to evaluate the associations between neonatal and familiar factors and childhood asthma and allergic diseases, and to examine the modification effects of breastfeeding on the associations assessed. Results : Of 10,464 primary school children aged 6-11 years, the overall prevalence of childhood asthma, allergic rhinitis, urticarial, food allergy and drug allergy was 13.9%, 22.7%, 15.3%, 8.1% and 4.6%, respectively. Male sex, high socioeconomic status, cesarean section delivery, only one child in the household and having family history of allergy were among the major risk factors for childhood asthma and allergic diseases while longer exclusive breastfeeding duration (>6 months) was a protective factor. Longer exclusive breastfeeding duration also attenuated the effects of neonatal and familiar risk factors on childhood asthma and allergic diseases. Conclusions : Longer exclusive breastfeeding duration was a protective factor against childhood asthma and allergic diseases, and also reduced the adverse effects of neonatal and familiar risk factors on these diseases. Giving the prevalence of childhood asthma and allergic diseases is rapidly rising across the globe, these findings may have important clinical and public health implications.
Publisher: Research Square Platform LLC
Date: 26-01-2021
DOI: 10.21203/RS.3.RS-105228/V2
Abstract: Background : Childhood asthma and allergic diseases are a significant global problem. There are inconsistent findings on the associations of delivery mode, the number of children in the household and breastfeeding with childhood asthma and allergic diseases. We assessed these associations and examined whether breastfeeding modified the effects of neonatal and familial risk factors on childhood asthma and allergic diseases. Methods : A population-based cross-sectional study was conducted in Shanghai, China. A total of 17 primary schools were randomly selected from 13 districts of Shanghai in this study. The International Study of Asthma and Allergies in Childhood questionnaire was adopted to assess the childhood asthma and allergic diseases. Multivariable logistic regression models were used to evaluate the associations between neonatal and familial factors and childhood asthma and allergic diseases, and to examine the modification effects of breastfeeding on the associations assessed. Results : Of 10,464 primary school children aged 6-11 years, the overall prevalence of childhood asthma, allergic rhinitis, urticaria, food allergy and drug allergy was 13.9%, 22.7%, 15.3%, 8.1% and 4.6%, respectively. Male sex, high socioeconomic status, cesarean section delivery, only one child in the household and having family history of allergy were associated with increased odds ratio (OR) of childhood asthma and allergic diseases while longer breastfeeding duration (>6 months) was inversely associated with these diseases. Longer breastfeeding duration also attenuated the OR of neonatal and familial risk factors on childhood asthma and allergic diseases. For instance, the adjusted OR of childhood asthma in the group of vaginal delivery and breastfeeding duration 6 months was lowest (0.78, 95% confidence interval: 0.66, 0.92). Conclusions : Longer breastfeeding duration was inversely associated with childhood asthma and allergic diseases, and also reduced the OR of neonatal and familial risk factors on these diseases. Giving the prevalence of childhood asthma and allergic diseases is rapidly rising across the globe, these findings may have important clinical and public health implications.
Publisher: Oxford University Press (OUP)
Date: 13-10-2022
DOI: 10.1093/IJE/DYAC197
Publisher: Elsevier BV
Date: 03-2020
DOI: 10.1016/J.SCITOTENV.2019.135975
Abstract: Non-optimal weather conditions and air pollution pose a significant threat to children's health. However, the relative impact of different environmental exposures on childhood allergic diseases remains unclear. This study aimed to quantify the relative impact of meteorological factors and air pollutants on childhood allergic diseases in Shanghai, China. Data on clinical visits due to childhood asthma, allergic rhinitis (AR) and atopic dermatitis (AD) from 2007 to 2017 in Shanghai were collected from Shanghai Children's Medical Center and Xinhua Hospital. The meteorological data (i.e. daily mean temperature, temperature difference, air pressure, air pressure difference, precipitation, relative humidity, sunshine and wind speed) for the same period were obtained from the Shanghai Meteorological Center. Air pollution data (PM There were a total of 2,410,392 cases of childhood allergic diseases, including 975,771 asthma, 646,975 AR and 787,646 AD. Most of environmental factors were significantly associated with childhood allergic diseases. Daily mean temperature (standard β: -0.076 (95% confidence interval (CI): -0.086, -0.067)) and air pressure (standard β: 0.075 (95% CI: 0.068, 0.082)) seemed to play more important roles than other environmental factors in the occurrence of these allergic diseases. The numbers of these allergic diseases attributable to an interquartile range (IQR) change in meteorological factors also appeared to be greater than those attributable to an IQR change in air pollutants. Both climatic variation and air pollution were associated with childhood allergic diseases, but the former appeared to play a more important role in the occurrence of these diseases. These findings may have significant implications for the development of tailored strategies to prevent these rapidly-increasing diseases worldwide.
Publisher: Elsevier BV
Date: 05-2023
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