ORCID Profile
0000-0003-2621-8326
Current Organisations
Institute of Process Engineering Chinese Academy of Sciences
,
中国科学院过程工程研究所
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Publications
Possibilities for an Aerial Biosphere in Temperate Sub Neptune-Sized Exoplanet Atmospheres
Publisher: MDPI AG
Date: 31-05-2021
Abstract: The search for signs of life through the detection of exoplanet atmosphere biosignature gases is gaining momentum. Yet, only a handful of rocky exoplanet atmospheres are suitable for observation with planned next-generation telescopes. To broaden prospects, we describe the possibilities for an aerial, liquid water cloud-based biosphere in the atmospheres of sub Neptune-sized temperate exoplanets, those receiving Earth-like irradiation from their host stars. One such planet is known (K2-18b) and other candidates are being followed up. Sub Neptunes are common and easier to study observationally than rocky exoplanets because of their larger sizes, lower densities, and extended atmospheres or envelopes. Yet, sub Neptunes lack any solid surface as we know it, so it is worthwhile considering whether their atmospheres can support an aerial biosphere. We review, synthesize, and build upon existing research. Passive microbial-like life particles must persist aloft in a region with liquid water clouds for long enough to metabolize, reproduce, and spread before downward transport to lower altitudes that may be too hot for life of any kind to survive. Dynamical studies are needed to flesh out quantitative details of life particle residence times. A sub Neptune would need to be a part of a planetary system with an unstable asteroid belt in order for meteoritic material to provide nutrients, though life would also need to efficiently reuse and recycle metals. The origin of life may be the most severe limiting challenge. Regardless of the uncertainties, we can keep an open mind to the search for biosignature gases as a part of general observational studies of sub Neptune exoplanets.
Biochemical engineering in China
Publisher: Walter de Gruyter GmbH
Date: 08-03-2019
Abstract: Chinese biochemical engineering is committed to supporting the chemical and food industries, to advance science and technology frontiers, and to meet major demands of Chinese society and national economic development. This paper reviews the development of biochemical engineering, strategic deployment of these technologies by the government, industrial demand, research progress, and breakthroughs in key technologies in China. Furthermore, the outlook for future developments in biochemical engineering in China is also discussed.
Biomimetically Engineered Demi‐Bacteria Potentiate Vaccination against Cancer
Publisher: Wiley
Date: 15-06-2017
Abstract: Failure in enhancing antigen immunogenicity has limited the development of cancer vaccine. Inspired by effective immune responses toward microorganisms, demi‐bacteria (DB) from Bacillus are engineered as carriers for cancer vaccines. The explored hydrothermal treatment enables the Bacillus to preserve optimal pathogen morphology with intrinsic mannose receptor agonist. Meanwhile, the treated Bacillus can be further endowed with ideal hollow orous structure for efficient accommodation of antigen and adjuvant, such as CpG. Therefore, this optimal engineered nanoarchitecture allows multiple immunostimulatory elements integrate in a pattern closely resembling that of bacterial pathogens. Such pathogen mimicry greatly enhances antigen uptake and cross‐presentation, resulting in stronger immune activation suitable for cancer vaccines. Indeed, DB‐based biomimetic vaccination in mice induces synergistic cellular and humoral immune responses, achieving potent therapeutic and preventive effects against cancer. Application of microorganism‐sourced materials thus presents new opportunities for potent cancer therapy.
Related Organisations
Institute Of Process Engineering Chinese Academy Of Sciences
Location: China
Related Funding Activities
No related grants have been discovered for Hua Yue.