ORCID Profile
0000-0003-0339-1249
Current Organisation
University of Oxford
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Publisher: Informa UK Limited
Date: 11-2013
Publisher: Informa UK Limited
Date: 05-2013
Publisher: Informa UK Limited
Date: 07-2002
Publisher: Informa UK Limited
Date: 02-2013
Publisher: Springer Nature Singapore
Date: 2021
Publisher: University of Waikato
Date: 31-08-2013
Publisher: Springer Science and Business Media LLC
Date: 11-12-2015
Publisher: Informa UK Limited
Date: 11-2006
Publisher: Oxford University Press
Date: 24-05-2017
DOI: 10.1093/ACREFORE/9780190264093.013.96
Abstract: This article examines teacher education accountability and argues for new emphases in accreditation and beginning teacher certification designed to professionalize teacher education. A brief overview of the history of teacher education policy is presented as a background framing for exploring the current policy moment positioning teacher education as a problem that needs to be fixed. Government responses discussed are mainly those in the Anglophone areas of Australia, North America, and the United Kingdom. These involve tighter regulation while at the same time opening up a deregulated teacher education environment as well as an increasing focus on measuring the contribution that teacher preparation makes to student learning. The article suggest ways of professionalizing teacher education accountability which go beyond the “partnerships,” “classroom-ready,” and “value-added” mantras of current debates and policies and considers (1) teacher education in a new hybrid space, (2) authentic graduate assessments, and (3) rigorous research evidence as the cornerstones of a refreshed and more professionalised approach to teacher education accountability.
Publisher: Elsevier BV
Date: 2022
Publisher: Informa UK Limited
Date: 11-2011
Publisher: Springer Science and Business Media LLC
Date: 31-12-2014
Publisher: Informa UK Limited
Date: 18-01-2011
Publisher: Springer Netherlands
Date: 2011
Publisher: Springer Nature Singapore
Date: 2021
Publisher: Informa UK Limited
Date: 04-2003
Publisher: Routledge
Date: 19-06-2013
Publisher: Informa UK Limited
Date: 04-2003
Publisher: Edith Cowan University
Date: 10-2017
Publisher: Informa UK Limited
Date: 12-10-2020
Publisher: Informa UK Limited
Date: 04-0003
Publisher: Springer Singapore
Date: 2017
Publisher: Oxford University Press
Date: 19-12-2017
DOI: 10.1093/ACREFORE/9780190264093.013.305
Abstract: The past decade has seen increasing federal intervention in teacher education in Australia, and like many other countries, more attention on teacher education as a policy problem. The current policy context calls for graduates from initial teacher education programs to be classroom ready and for teacher education programs to provide evidence of their effectiveness and their impact on student learning. It is suggested that teacher educators currently lack sufficient evidence and response to criticisms of effectiveness and impact. However, examination of the relevant literature and analysis of the discourses informing current policy demonstrate that it is the issue of how effectiveness is understood and framed, and what constitutes evidence of effectiveness, that needs closer examination by both teacher educators and policymakers before evidence of impact can be usefully claimed—or not.
Publisher: Informa UK Limited
Date: 27-10-2010
Publisher: Informa UK Limited
Date: 03-2006
Publisher: Informa UK Limited
Date: 11-2012
Publisher: Springer Nature Singapore
Date: 2021
Publisher: Springer International Publishing
Date: 2016
Publisher: Springer Netherlands
Date: 2001
Publisher: Informa UK Limited
Date: 21-09-2019
Publisher: Informa UK Limited
Date: 07-2005
Publisher: Informa UK Limited
Date: 15-07-2011
Publisher: Springer Netherlands
Date: 2005
Publisher: Springer Berlin Heidelberg
Date: 2013
Publisher: Informa UK Limited
Date: 08-2011
Publisher: Life Science Alliance, LLC
Date: 11-05-2022
Abstract: Pathogenic mycobacteria inhibit inflammasome activation to establish infection. Although it is known that potassium efflux is a trigger for inflammasome activation, the interaction between mycobacterial infection, potassium efflux, and inflammasome activation has not been investigated. Here, we use Mycobacterium marinum infection of zebrafish embryos and Mycobacterium tuberculosis infection of THP-1 cells to demonstrate that pathogenic mycobacteria up-regulate the host WNK signalling pathway kinases SPAK and OXSR1 which control intracellular potassium balance. We show that genetic depletion or inhibition of OXSR1 decreases bacterial burden and intracellular potassium levels. The protective effects of OXSR1 depletion are at least partially mediated by NLRP3 inflammasome activation, caspase-mediated release of IL-1β, and downstream activation of protective TNF-α. The elucidation of this druggable pathway to potentiate inflammasome activation provides a new avenue for the development of host-directed therapies against intracellular infections.
Publisher: Informa UK Limited
Date: 02-2012
Publisher: Informa UK Limited
Date: 04-2000
Publisher: Springer Science and Business Media LLC
Date: 20-12-2019
Publisher: Springer Singapore
Date: 2016
Publisher: Informa UK Limited
Date: 19-03-2012
Location: United States of America
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Diane Mayer.