ORCID Profile
0000-0003-4726-5746
Current Organisation
Mahatma Gandhi University
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Publisher: Wiley
Date: 08-06-2018
Publisher: Wiley
Date: 08-07-2017
DOI: 10.1002/APP.45447
Publisher: Elsevier BV
Date: 09-2013
Publisher: Elsevier BV
Date: 03-2005
Publisher: Springer Science and Business Media LLC
Date: 02-06-2016
Publisher: Springer Science and Business Media LLC
Date: 12-12-2016
DOI: 10.1038/SREP37731
Abstract: Metal nanowires exhibit unusually high catalytic activity towards oxygen reduction reaction (ORR) due to their inherent electronic structures. However, controllable synthesis of stable nanowires still remains as a daunting challenge. Herein, we report the in situ synthesis of silver nanowires (AgNWs) over boron doped graphene sheets (BG) and demonstrated its efficient electrocatalytic activity towards ORR for the first time. The electrocatalytic ORR efficacy of BG-AgNW is studied using various voltammetric techniques. The BG wrapped AgNWs shows excellent ORR activity, with very high onset potential and current density and it followed four electron transfer mechanism with high methanol tolerance and stability towards ORR. The results are comparable to the commercially available 20% Pt/C in terms of performance.
Publisher: Elsevier BV
Date: 10-2013
Publisher: Elsevier BV
Date: 03-2015
DOI: 10.1016/J.ADDR.2014.12.002
Abstract: Wound healing is a dynamic and complex phenomenon of replacing devitalized tissues in the body. Urethral healing takes place in four phases namely inflammation, proliferation, maturation and remodelling, similar to dermal healing. However, the duration of each phase of wound healing in urology is extended for a longer period when compared to that of dermatology. An ideal wound dressing material removes exudate, creates a moist environment, offers protection from foreign substances and promotes tissue regeneration. A single wound dressing material shall not be sufficient to treat all kinds of wounds as each wound is distinct. This review includes the recent attempts to explore the hidden potential of growth factors, stem cells, siRNA, miRNA and drugs for promoting wound healing in urology. The review also discusses the different technologies used in hospitals to treat wounds in urology, which make use of innovative biomaterials synthesised in regenerative medicines like hydrogels, hydrocolloids, foams, films etc., incorporated with growth factors, drug molecules or nanoparticles. These include surgical zippers, laser tissue welding, negative pressure wound therapy, and hyperbaric oxygen treatment.
Publisher: Wiley
Date: 26-01-2006
DOI: 10.1002/APP.23450
Publisher: Elsevier BV
Date: 12-2016
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C4TC01037J
Abstract: The current study focuses on giving a basic understanding of tubular graphene sheets or carbon nanotubes (CNTs) and points towards their role in fabricating elastomer composites.
Publisher: American Chemical Society (ACS)
Date: 24-02-2011
DOI: 10.1021/IE102259S
Publisher: American Chemical Society (ACS)
Date: 21-10-2013
DOI: 10.1021/AM403436Y
Abstract: Exploring the possibility of using inorganic faujasites in tissue engineering scaffolds is a prospective approach in regenerative medicine. Novel gelatin/hyaluronic acid (HA)/faujasite porous scaffolds with low surface energy were fabricated by lyophilization. The pore size of gelatin/HA scaffold was 50-2000 μm, whereas it was greatly reduced to 10-250 μm after incorporation of 2.4% (w/w) of faujasites in polymer matrix, GH(2.4%). Micro computed tomography analysis showed that the porosity of GH(2.4%) was 90.6%. The summative effect was ideal for growth of dermal fibroblasts and cellular attachment. XRD analysis revealed that the embedded faujasites maintained their crystallinity in the polymer matrix even though they interacted with the polymers as indicated by FT-IR analysis. Coupling with effective reinforcement of faujasites, GH(2.4%) demonstrated compression modulus of 929 ± 7 Pa and glass transition temperature of 31 ± 0.05 °C. It exhibited controlled swelling and degradation, allowing sufficient space for tissue regrowth. The latter is further supported by capability of faujasites to provide efficient oxygen supply to fibroblast cells. GH(2.4%) showed a cell viability of 91 ± 8% on NIH 3T3 fibroblast cell lines. The in vivo studies on Sprague-Dawley rats revealed its ability to enhance wound healing by accelerating re-epithelization and collagen deposition. These findings indicated its potential as excellent wound dressing material.
Publisher: American Chemical Society (ACS)
Date: 18-11-2009
DOI: 10.1021/IE9007503
Publisher: Springer International Publishing
Date: 2014
Publisher: Elsevier BV
Date: 03-2014
DOI: 10.1016/J.COLSURFB.2013.11.048
Abstract: In this article, gelatin/copper activated faujasites (CAF) composite scaffolds were fabricated by lyophilisation technique for promoting partial thickness wound healing. The optimised scaffold with 0.5% (w/w) of CAF, G (0.5%), demonstrated pore size in the range of 10-350 μm. Agar disc diffusion tests verified the antibacterial role of G (0.5%) and further supported that bacterial lysis was due to copper released from the core of CAF embedded in the gelatin matrix. The change in morphology of bacteria as a function of CAF content in gelatin scaffold was studied using SEM analysis. The confocal images revealed the increase in mortality rate of bacteria with increase in concentration of incorporated CAF in gelatin matrix. Proficient oxygen supply to needy cells is a continuing hurdle faced by tissue engineering scaffolds. The dissolved oxygen measurements revealed that CAF embedded in the scaffold were capable of increasing oxygen supply and thereby promote cell proliferation. Also, G (0.5%) exhibited highest cell viability on NIH 3T3 fibroblast cells which was mainly attributed to the highly porous architecture and its ability to enhance oxygen supply to cells. In vivo studies conducted on Sprague Dawley rats revealed the ability of G (0.5%) to promote skin regeneration in 20 days. Thus, the obtained data suggest that G (0.5%) is an ideal candidate for wound healing applications.
Publisher: American Scientific Publishers
Date: 09-2015
Abstract: The biocompatibility and excellent ion exchange capacity make faujasites ideal candidates for tissue engineering applications. A novel pectin/copper exchanged faujasite hybrid membrane was synthesized by solvent casting technique, using calcium chloride as the crosslinking agent. AFM images revealed the egg-box model organization of calcium cross-linked pectin chains used as a matrix. The morphology of composite membranes was characterized by SEM and their elemental composition was determined using EDX. The higher contact angle of P (1%) when compared to that of native pectin figured out an enhanced hydrophobicity of hybrid material. The embedded faujasite particles maintained their crystalline structure as revealed by XRD and their interactions with the polymer matrix was evaluated by FTIR. The composite membrane with 1% (w/w) of copper exchanged faujasite, P(1%), exhibited better thermal stability, excellent antibacterial activity, controlled swelling and degradation. Finally, it displayed cell viability of 89% on NIH3T3 fibroblast cell lines and aided in improving wound healing and re-epithelialisation in Sprague Dawley rats. The obtained data suggested their potential as ideal matrices for efficient treatment of burn wounds.
Publisher: Elsevier BV
Date: 2005
Publisher: Elsevier BV
Date: 10-2014
Publisher: Wiley
Date: 16-03-2017
DOI: 10.1002/APP.45059
Publisher: Elsevier BV
Date: 05-2015
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1MA00444A
Abstract: 3D printing provides numerous opportunities for designing tissue engineering constructs with intricate porosity, geometry and favourable mechanical properties and has the potential to revolutionize medical treatments.
Publisher: Informa UK Limited
Date: 22-06-2015
Publisher: Elsevier BV
Date: 10-2015
Publisher: Elsevier BV
Date: 06-2004
Publisher: Rubber Division, ACS
Date: 06-2016
DOI: 10.5254/RCT.15.84841
Abstract: Oil spills due to either accidents or deliberate oily discharges cause severe pollution and can be thwarted if proper detection facilities are applied. This article reports new flexible oil sensor capabilities of three different elastomer (natural rubber, butyl rubber, and styrene–isoprene–styrene copolymer) composites of multiwalled carbon nanotubes (MWCNTs). We highlight the sensor manufacturing by simple means of solution mixing, and the uniform dispersion of MWCNTs in the elastomers is substantiated with the help of morphology and structural analyses. Electrical percolation and semiconductor characteristics were also examined for composites. The developed materials show better oil sensing above the percolation level, and the filler–polymer interfacial interaction is the main factor regulating the oil-detecting capability. The efficiency of the sensors was also tested after many instances of bending.
Publisher: Elsevier BV
Date: 04-2014
Publisher: Elsevier BV
Date: 04-2014
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C4RA01429D
Abstract: Stereochemistry is proposed to contribute to the miscibility of poly(trimethylene terephthalate) (PTT) and bisphenol-A diglycidyl ether (BADGE), since molecular conformation is one of the determinants of the close packing ability and hence the interactions of such a system.
Publisher: Elsevier BV
Date: 07-2017
Publisher: Elsevier BV
Date: 2006
Publisher: Elsevier BV
Date: 03-2014
Publisher: Royal Society of Chemistry (RSC)
Date: 2013
DOI: 10.1039/C3RA41395K
No related grants have been discovered for sabu thomas.