ORCID Profile
0000-0001-6877-7383
Current Organisations
RMIT University
,
University of Melbourne
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In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Artificial Intelligence and Image Processing | Heat and Mass Transfer Operations | Building Not Elsewhere Classified | Neural Networks, Genetic Alogrithms And Fuzzy Logic | Simulation And Modelling | Statistics | Numerical Computation | Virtual Reality and Related Simulation | Numerical Analysis | Simulation and Modelling | Stochastic Analysis and Modelling | Functional Materials | Manufacturing Processes and Technologies (excl. Textiles) | Materials Engineering | Interdisciplinary Engineering | Composite and Hybrid Materials |
Expanding Knowledge in Engineering | Application packages | Polymeric Materials (e.g. Paints) | Environmentally Sustainable Manufacturing not elsewhere classified | Expanding Knowledge in Built Environment and Design | Expanding Knowledge in Technology | Industrial Energy Conservation and Efficiency | Housing | Housing | Aerospace Equipment | Expanding Knowledge in the Mathematical Sciences
Publisher: Elsevier BV
Date: 08-2009
Publisher: SAE International
Date: 15-09-2015
DOI: 10.4271/2015-01-2571
Publisher: Emerald
Date: 18-03-2022
Abstract: The purpose of this paper is to investigate the development process of the fire whirl in the fixed-frame facility and focus on the impacts of the fire whirl’s vortex core on the formation and flame structure of the fire whirl. The complex turbulent reacting flame surface is captured by the large eddy simulation turbulence closure coupled with two sub-grid scale (SGS) kinetic schemes (i.e. the chemistry equilibrium and steady diffusion flamelet). Numerical predictions are validated thoroughly against the measurements by Lei et al. (2015) with excellent agreements. A double maximum tangential velocity refinement approach is proposed to quantify the vortex cores’ instantaneous location and region, addressing the missing definition in other studies. The numerical results show that the transition process of the fire whirl is dominated by the vortex core movement, which is related to the centripetal force. The unsteadiness of the fully developed fire whirl was found depending on the instantaneous fluctuation of heat release rate. The steady diffusion flamelet scheme is essential to capture the instantaneous fluctuation. Furthermore, the axial velocity inside the vortex core is the key to determining the state of fire whirl. Due to intensive interactions between buoyant fires and ambient rotating flow, the on-set and formation of fire whirl still remain largely elusive. This paper focused on the transition process of fire whirl between different development stages. This paper provides insights into the transition process from the inclined flame to the fire whirls based on the centripetal force. This paper presented and compared two SGS kinetic schemes to resolve the fire whirl development process and the unsteadiness of its vortical structures. The modelling framework addresses the shortcoming of previous numerical studies where RANS turbulence closure and simplified combustion kinetics was adopted. Numerical results also revealed the fire whirl transition process and its relationship to centripetal force.
Publisher: Springer Science and Business Media LLC
Date: 04-03-2011
Publisher: Elsevier BV
Date: 10-2013
Publisher: World Scientific Pub Co Pte Ltd
Date: 10-01-2013
DOI: 10.1142/S0219519413500012
Abstract: It is a well-established fact that atherosclerosis in carotid bifurcation depends on flow parameters such as wall shear stress, flow pulsatility, and blood pressure. However, it is still not clearly verified how atherosclerosis can become aggravated when plaque experiences a high level of shear stress during advance stages of this disease. In this paper, fluid and structural properties in idealistic geometries are analyzed by using fluid-structure interaction (FSI). From our results, the relationship among blood pressure, stenotic compression, and deformation was established. We show that a high level of compression occurs at the stenotic apex, and can potentially be responsible for plaque progression. Moreover, wall shear stress and deformation are significantly affected by the degree of stenosis. Finally, through analysis of the FSI-based simulation results, we can better understand the parameters that influence flow through a stenotic artery and plaque aggravation, and apply the knowledge for the enhancement of clinical research and prediction of treatment outcomes.
Publisher: Springer Science and Business Media LLC
Date: 22-03-2020
Publisher: Elsevier BV
Date: 12-2013
Publisher: Elsevier BV
Date: 10-2022
Publisher: AIP
Date: 2010
DOI: 10.1063/1.3452283
Publisher: MDPI AG
Date: 2020
DOI: 10.3390/APP10010318
Abstract: A numerical study of the fire whirl formation under symmetrical and asymmetrical entraining configuration is presented. This work aims to assess the effect of eddy-generation configuration on the evolution of the intriguing phenomenon coupled with both flow dynamics and combustion. The numerical framework implements large-eddy simulation, detailed chemistry to capture the sophisticated turbulence-chemistry interaction under reasonable computational cost. It also adopts liquid-based clean fuel with fixed injection rate and uniformed discretisation scheme to eliminate potential interference introduced by various aspects of uncertainties. The result reveals that the nascent fire whirl formulates significantly rapidly under the symmetrical two-slit configuration, with extended flame height and constrained vortex structure, compared with the asymmetrical baseline. However, its revolution orbit gradually erges from domain centreline and eventually stabilises with a large radius of rotation, whereas the revolution pattern of that from the baseline case is relatively unchanged from the inception of nascent fire whirl. Through the analysis, the observed difference in evaluation pathway could be explained using the concept of circular motion with constant centripetal force. This methodology showcases its feasibility to reveal and visualise the fundamental insight and facilitate profound understanding of the flaming behaviour to benefit both research and industrial sectors.
Publisher: Elsevier BV
Date: 07-2004
Publisher: Elsevier BV
Date: 10-2014
Publisher: Elsevier BV
Date: 03-2012
Publisher: SAGE Publications
Date: 03-2012
Abstract: In the numerical study, investigation of bubbly flow requires deep understanding of complex hydrodynamics under various flow conditions. In order to simulate the bubble behaviour in conjunction with suitable bubble coalescence and bubble breakage kernels, direct quadrature method of moments (DQMOM) has been applied and validated instead. To examine the predictive results from DQMOM model, the validation has been carried out against experimental data of Lucas et al. (2005) and Prasser et al. (2007) measured in the Forschungszentrum Dresden-Rossendorf FZD facility. Numerical results showed good agreement against experimental data for the local and axial void fraction, bubble size distribution and interfacial area concentration profiles. Encouraging results demonstrates the prospect of the DQMOM two-fluid model against flow conditions with wider range of bubble sizes and rigorous bubble interactions. Moreover, moment sensitivity study also has been carried out to carefully assess the performance of the model. In order to perform the moment sensitivity test three different moment criteria has chosen – as 4 moments, 6 moments and 8 moments. Close agreement between the predictions and measurement was found and it appeared that increasing the number of moments does not have much significance to improve the conformity with experimental data. Nonetheless, increasing the number of moments merely contribute to perform the calculation expensive in terms of computational resource and time. Based on the present study, this preliminary assessment has definitely served to demonstrate and exploit DQMOM model's capabilities to handle wider range of bubble sizes as well as moment resolution required to achieve moment independent solution.
Publisher: Elsevier BV
Date: 05-2019
Publisher: Wiley
Date: 18-04-2008
DOI: 10.1002/AIC.11503
Publisher: American Society for Microbiology
Date: 31-05-2023
DOI: 10.1128/JVI.00451-23
Publisher: SAGE Publications
Date: 13-07-2021
DOI: 10.1177/1420326X211031276
Abstract: A high-performance smoke exhaust system is vital for maintaining a tenable environment during fire accidents evacuation. This study proposes a novel vortex flow driven smoke exhaust system to delay the smoke filling process during the atrium fire accident. The complex fluid movement and combustion reactions were predicted using Fire Dynamics Simulator, and the predicted smoke filling process was identified by the least-square method. Good agreements between numerical predictions and experimental measurements for vertical temperature, tangential velocity profile and smoke interface height were achieved. The numerical outcomes revealed that the amount of fresh air supplied, heat release rate and exhaust fan's rate determined the smoke interface's final height. A parametric study was also carried out to investigate the dominating factor in maintaining a stable vortex flow to maximize the smoke exhaust efficiency. Numerical results showed that the vortex flow smoke exhaust system could slow down the smoke filling, and the stability of the swirling fire is crucial for the system's performance.
Publisher: Elsevier BV
Date: 03-2011
Publisher: Elsevier BV
Date: 03-2018
Publisher: Trans Tech Publications, Ltd.
Date: 08-2010
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.29-32.143
Abstract: The aim of the study was to develop a numerical model to reproduce the bubbly flow field created by ventilated cavity which includes three different regions. The model was established based on the Eulerian-Eulerian two-fluid model coupled with a population balance approach which is solved by the Homogeneous Multiple-Size-Group (MUSIG) model to predict bubble size distribution. Base on the model, the simulation was carried out at the experimental condition of Su et al. (1995). Firstly three regions were successfully captured proved by the spatial voidage distribution and streamline shape. Then distributions of void fraction and Sauter mean bubble diameter at various sections below the cavity corresponding to three regions respectively were plotted against experimental data. A close agreement was observed in the void fraction distribution which indicates that qualitative details of the structure of the two-phase flow field below the cavity was successfully produced. The Sauter mean bubble diameter in the pipe flow region was under-predicted for about 10%. In conclusion, the proposed model was validated in predicting the multi-region flow field below the ventilated cavity which will provide a valuable insight in designing and controlling of the two phase systems with the detailed flow field information obtained.
Publisher: Begell House
Date: 2015
Publisher: American Chemical Society (ACS)
Date: 23-09-2020
Publisher: Elsevier BV
Date: 09-2007
Publisher: Elsevier BV
Date: 10-2006
Publisher: American Society for Microbiology
Date: 22-06-2023
Publisher: Elsevier BV
Date: 10-2012
Publisher: Elsevier BV
Date: 05-2021
Publisher: Elsevier BV
Date: 09-2018
Publisher: American Society for Microbiology
Date: 15-03-2018
DOI: 10.1128/JVI.01404-18
Abstract: The genome sequences of the koala and wombat gammaherpesviruses show that the viruses form a distinct branch, indicative of a novel genus within the Gammaherpesvirinae . Their genomes contain several new ORFs, including ORFs encoding a β-galactoside α-2,6-sialyltransferase that is phylogenetically closest to poxvirus and insect homologs and the first reported viral NTPDase. NTPDases are ubiquitously expressed in mammals and are also present in several parasitic, fungal, and bacterial pathogens. In mammals, these cell surface-localized NTPDases play essential roles in thromboregulation, inflammation, and immune suppression. In this study, we demonstrate that the virus-encoded NTPDase is enzymatically active and is transcribed during natural infection of the host. Understanding how these enzymes benefit viruses can help to inform how they may cause disease or evade host immune defenses.
Publisher: Elsevier BV
Date: 2012
Publisher: American Scientific Publishers
Date: 06-2011
Publisher: SAGE Publications
Date: 20-09-2018
Abstract: In this article, a generic framework was proposed to effectively characterise the pyrolysis kinetics of any household furniture materials. To examine the validity of this method, two wooden polymeric s les, (1) furniture plywood and (2) particle board, were experimented through thermogravimetric and differential thermal analyses, as well as cone calorimetry. The framework comprises of three major parameterisation procedures including (1) using the Kissinger method for the initial approximation, (2) modification of modelling constants and (3) optimisation by comparisons with the experimental results. The finalised pyrolysis kinetics was numerically investigated through computational fluid dynamics simulation of the cone calorimeter. Numerical predictions were validated against the experimental data for three different cone radiation intensities. Good agreement was achieved between the computational and experimental results in terms of heat release rate, ignition time and burn duration. The proposed framework was capable of establishing quality pyrolysis kinetics that fully replicates the complex thermal decomposition of solid combustible materials.
Publisher: ASME International
Date: 15-03-2017
DOI: 10.1115/1.4035805
Abstract: Modeling subcooled boiling flows in vertical channels has relied heavily on the utilization of empirical correlations for the active nucleation site density, bubble departure diameter, and bubble departure frequency. Following the development and application of mechanistic modeling at low pressures, the capability of the model to resolve flow conditions at elevated pressure up to 10 bar is thoroughly assessed and compared with selected empirical models. Predictions of the mechanistic and selected empirical models are validated against two experimental data at low to elevated pressures. The results demonstrate that the mechanistic model is capable of predicting the heat and mass transfer processes. In spite of some drawbacks of the currently adopted force balance model, the results still point to the great potential of the mechanistic model to predict a wide range of flow conditions in subcooled boiling flows.
Publisher: Elsevier BV
Date: 06-2003
Publisher: Elsevier BV
Date: 07-2018
Publisher: Springer Science and Business Media LLC
Date: 15-02-2012
Abstract: This study characterizes the distribution and components of plaque structure by presenting a three-dimensional blood-vessel modelling with the aim of determining mechanical properties due to the effect of lipid core and calcification within a plaque. Numerical simulation has been used to answer how cap thickness and calcium distribution in lipids influence the biomechanical stress on the plaque. Modelling atherosclerotic plaque based on structural analysis confirms the rationale for plaque mechanical examination and the feasibility of our simulation model. Meaningful validation of predictions from modelled atherosclerotic plaque model typically requires examination of bona fide atherosclerotic lesions. To analyze a more accurate plaque rupture, fluid-structure interaction is applied to three-dimensional blood-vessel carotid bifurcation modelling. A patient-specific pressure variation is applied onto the plaque to influence its vulnerability. Modelling of the human atherosclerotic artery with varying degrees of lipid core elasticity, fibrous cap thickness and calcification gap, which is defined as the distance between the fibrous cap and calcification agglomerate, form the basis of our rupture analysis. Finite element analysis shows that the calcification gap should be conservatively smaller than its threshold to maintain plaque stability. The results add new mechanistic insights and methodologically sound data to investigate plaque rupture mechanics. Structural analysis using a three-dimensional calcified model represents a more realistic simulation of late-stage atherosclerotic plaque. We also demonstrate that increases of calcium content that is coupled with a decrease in lipid core volume can stabilize plaque structurally.
Publisher: Springer Science and Business Media LLC
Date: 11-01-2012
Publisher: American Chemical Society (ACS)
Date: 26-07-2023
Publisher: Elsevier
Date: 2014
Publisher: Elsevier BV
Date: 2020
Publisher: Elsevier BV
Date: 2019
Publisher: SAGE Publications
Date: 12-2014
Publisher: Springer Science and Business Media LLC
Date: 22-03-2018
Publisher: SAGE Publications
Date: 03-2012
Abstract: Numerical simulation of flow through a realistic bifurcated carotid artery geometry with a stenosis has been conducted for comparison to experimental measurements. The behaviour of simplified therapeutic nanoparticles in relatively low concentration was observed using a discrete particle approach. The role of size (diameters from 500 nm to 50 nm) in determining particle residence time and the potential for both desirable and undesirable wall interactions was investigated. It was found that mean particle residence time reduced with decreasing particle diameter, and the percentage of particles experiencing one or more wall interactions increased simultaneously. Further simulations were conducted on a scaled-down version of the geometry which approximated the size and flow conditions of an arteriole with capillary branches, and in this instance the mean residence time increased with decreasing particle diameter, owing largely to the greater influence of Brownian motion. 33% of all 50 nm particles were involved in wall interactions, indicating that smaller particles would have a greater ability to target, for instance, cancerous tumours in such regions.
Publisher: Elsevier BV
Date: 10-2016
Publisher: Elsevier BV
Date: 08-2014
Publisher: SAGE Publications
Date: 27-08-2018
Abstract: In this paper, the mechanistic wall heat partitioning approach was used to capture the complex heat and mass transfer in sub-cooled boiling flows. In order to accommodate the changes of local variables to be relevant to the physical properties of sub-cooled fluids, the Wet-Steam (IAPWS-IF97) is used as the working fluid. Currently, the approach is evaluated based on the bubble sliding along the wall before lifting-off, which is usually found in the flow boiling situations. In the simulation, the closure mechanistic models, including the fractal analysis, the force balance and the mechanistic frequency, were coupled with the Eulerian–Eulerian two-fluid framework, while the Shear Stress Transport model was used as a turbulent modelling closure. The Multiple Size Group model was introduced to handle the bubble interactions and predict the bubble size distribution. Moreover, the effect of adopting the sub-cooled liquid properties into the modelling was investigated and compared with the experiments over a wide range of flow conditions. Specifically, the predicted void fraction and the sub-cooling temperature near the heated wall were precisely compared with the cases of using the constant-property liquid. Overall, the satisfactory agreements were found between the experiments and the predictions of the liquid temperature, void fraction, interfacial area concentration, Sauter mean diameter and bubble and liquid velocities with the exception of the case of high heat and mass fluxes. To enhance the current prediction accuracy for a situation of having a high superheating temperature, more bubble interactions on the boiling wall, such as merging of the bubbles while sliding, need to be considered. Furthermore, to assess the model capability, this mechanistic approach will be introduced to elucidate the sub-cooled boiling flow in situations of using different fluids in the near future.
Publisher: Elsevier BV
Date: 08-2014
Publisher: SAGE Publications
Date: 06-2010
DOI: 10.1260/1757-482X.2.2.101
Abstract: In this study, an Eulerian–Eulerian two-fluid model integrated with the population balance approach based on Multiple-Size-Group (MUSIG) model was proposed to simulate on the gas leakage bubbly wake of a ventilated cavitation problem. Three selected flow conditions with Froude number ranging from 20 to 29 have been selected for investigation. Predicted void fraction and bubble velocity profiles were validated against the experimental measurements in the high-speed water tunnel of Schauer (2003) and Wosnik (2005). Sensitivity studies on the mesh resolution and three different turbulence closures were first carried out. In comparison with experimental data, the shear stress transport (SST) turbulence model was found to be the best candidate in modelling the re-circulation motions within the cavity wake region. To consider the neighbouring effect of closely packed bubbles, an empirical equation was proposed to correlate the turbulent dispersion coefficient to the local gas void fraction. Based on the proposed empirical equation, the turbulent dispersion coefficient reduces to 0.1 when local gas void fraction is higher than 60%. In general, numerical predictions were in satisfactory agreement with the experimental data. Some discrepancies have nonetheless been found between the numerical and experimental results. The lack of exact gas leakage mechanism remains an outstanding challenge in determining the actual gas leakage rate and initial bubble size from the continuous cavity. Further effort should be also focused on combing free-surface tracking model with the present population balance approach to investigate the complex vortex structure and interaction between ventilated cavity and discrete leakage bubbles.
Publisher: Wiley
Date: 21-05-2015
DOI: 10.1002/CJCE.22196
Publisher: Elsevier BV
Date: 2012
Publisher: Elsevier BV
Date: 03-2012
Publisher: Elsevier BV
Date: 2022
Publisher: ASTM International
Date: 2011
DOI: 10.1520/JAI103374
Publisher: Elsevier BV
Date: 08-2021
Publisher: Informa UK Limited
Date: 02-05-2016
Publisher: Elsevier BV
Date: 09-2022
Publisher: WIT Press
Date: 07-2014
DOI: 10.2495/HT140171
Publisher: American Chemical Society (ACS)
Date: 15-09-2020
Publisher: MDPI AG
Date: 02-05-2023
DOI: 10.3390/MET13050880
Abstract: The blowing flow is a key factor in molten bath stirring to affects the steel-bath interface fluctuation and chemical reaction in the top-bottom-blowing converter. The Volume of Fluid (VOF) method is widely used to capture the gas-liquid interface. However, some limitations exist in dealing with the interface curvature and normal vectors of the complex deformed slag-bath interface. The Coupled Level-Set and Volume of Fluid (CLSVOF) method uses the VOF function to achieve mass conservation and capture interface smoothly by computing the curvature and normal vector using the Level-Set function to overcome the limitations in the VOF model. In the present work, a three-dimensional (3D) transient mathematical model coupled CLSVOF method has been developed to analyze the mixing process under different injection flow rates and bottom-blowing positions. The results show that when the bottom-blowing flow rate increases from 0.252 kg/s to 0.379 kg/s, the mixing time in the molten bath gradually decreases from 74 s to 66 s. When the bottom-blowing flow rate is 0.252 kg/s, it is recommended to distribute the outer bottom-blowing position on concentric circles with Dtuy,2/D2 = 0.33.
Publisher: Elsevier BV
Date: 2019
Publisher: Elsevier BV
Date: 08-2007
Publisher: Informa UK Limited
Date: 31-08-2007
Publisher: IEEE
Date: 2007
Publisher: Elsevier BV
Date: 10-2018
Publisher: Elsevier BV
Date: 12-2014
Publisher: Hindawi Limited
Date: 2013
DOI: 10.1155/2013/638519
Abstract: Added-mass instability is known to be an important issue in the partitioned approach for fluid-structure interaction (FSI) solvers. Despite the implementation of the implicit approach, convergence of solution can be difficult to achieve. Relaxation may be applied to improve this implicitness of the partitioned algorithm, but this commonly leads to a significant increase in computational time. This is because the critical relaxation factor that allows stability of the coupling tends to be impractically small. In this study, a mathematical analysis for optimizing numerical performance based on different time integration schemes that pertain to both the fluid and solid accelerations is presented. The aim is to determine the most efficient configuration for the FSI architecture. Both theoretical and numerical results suggest that the choice of time integration schemes has a significant influence on the stability of FSI coupling. This concludes that, in addition to material and its geometric properties, the choice of time integration schemes is important in determining the stability of the numerical computation. A proper selection of the associated parameters can improve performance considerably by influencing the condition of coupling stability.
Publisher: Elsevier BV
Date: 09-2011
Publisher: Springer Science and Business Media LLC
Date: 15-08-2017
Publisher: Springer Science and Business Media LLC
Date: 03-2017
Publisher: Emerald
Date: 03-2002
DOI: 10.1108/09615530210418320
Abstract: This paper presents a comparison of numerical predictions employing a Computational Fluid Dynamics fire model against a series of turbulent buoyant fire experiments recently carried out in a two‐room compartment structure by Nielsen and Fleischmann at the University of Canterbuty, New Zealand. The model incorporates turbulence, combustion, soot generation and radiation due to a fire. An evaluation of the various approaches—volumetric heat source approach or a more sophisticated handling the fire through a combustion model—is carried out. The effect of radiation due to combustion products and soot is also investigated. The model considering combustion with radiation contribution by both the combustion products and soot provides the best agreement between the predicted results and measured data. The presence of soot is seen to significantly augment the global radiation process within the two‐compartment enclosure.
Publisher: Elsevier BV
Date: 08-2021
Publisher: American Society for Microbiology
Date: 27-06-2023
Publisher: SAGE Publications
Date: 06-2010
Abstract: In this study, the internal phase distributions of gas-liquid bubbly flow in a horizontal pipe have been predicted using the population balance model based on Average Bubble Number Density approach. Four flow conditions with average gas volume fraction ranging from 4.4% to 20% have been investigated. Predicted local radial distributions of void fraction, interfacial area concentration and gas velocity have been validated against the experimental data. In general, satisfactory agreements between predicted results and measured values have been achieved. For high superficial gas velocity, it has been ascertained that peak local void fraction of 0.7 with interfacial area concentration of 800 m −1 can be encountered near the top wall of the pipe. Some discrepancies have nonetheless been found between the numerical and experimental results at certain locations of the pipe. The insufficient resolution of the turbulent model in fully accommodating the strong turbulence in the current pipe orientation and the inclusion of additional interfacial force such as the prevalent bouncing force among bubbles remain some of the outstanding challenging issues need to be addressed in order to improve the prediction of horizontal gas-liquid bubbly flow.
Publisher: Informa UK Limited
Date: 02-08-2017
Publisher: Elsevier BV
Date: 02-2017
Publisher: Elsevier BV
Date: 09-2017
Publisher: Hindawi Limited
Date: 17-08-2021
DOI: 10.1111/CMI.13383
Abstract: Tracheitis associated with the chronic respiratory disease in chickens caused by Mycoplasma gallisepticum is marked by infiltration of leukocytes into the mucosa. Although cytokines/chemokines are known to play a key role in the recruitment, differentiation, and proliferation of leukocytes, those that are produced and secreted into the trachea during the chronic stages of infection with M. gallisepticum have not been described previously. In this study, the levels of transcription in the trachea of genes encoding a panel of 13 cytokines/chemokines were quantified after experimental infection with the M. gallisepticum wild-type strain Ap3AS in unvaccinated chickens and chickens vaccinated 40-, 48- or 57-weeks previously with the novel attenuated strain ts-304. These transcriptional levels in unvaccinated/infected and vaccinated/infected chickens were compared with those of unvaccinated/uninfected and vaccinated/uninfected chickens. Pathological changes and subsets of leukocytes infiltrating the tracheal mucosa were concurrently assessed by histopathological examination and indirect immunofluorescent staining. After infection, unvaccinated birds had a significant increase in tracheal mucosal thickness and in transcription of genes for cytokines/chemokines, including those for IFN-γ, IL-17, RANTES (CCLi4), and CXCL-14, and significant downregulation of IL-2 gene transcription. B cells, CD3
Publisher: MDPI AG
Date: 08-03-2019
DOI: 10.3390/EN12050910
Abstract: In this article, the evolution of in-flame soot species in a slow speed, buoyancy-driven diffusion flame is thoroughly studied with the implementation of the population balance approach in association with computational fluid dynamics (CFD) techniques. This model incorporates interactive fire phenomena, including combustion, radiation, turbulent mixing, and all key chemical and physical formation and destruction processes, such as particle inception, surface growth, oxidation, and aggregation. The in-house length-based Direct Quadrature Method of Moments (DQMOM) soot model is fully coupled with all essential fire sub-modelling components and it is specifically constructed for low-speed flames. Additionally, to better describe the combustion process of the parental fuel, ethylene, the strained laminar flamelet model, which considers detailed chemical reaction mechanisms, is adopted. Numerical simulation is validated against a self-conducted co-flow slot burner experimental measurement. A comprehensive assessment of the effect of adopting different nucleation laws, oxidation laws, and various fractal dimension and diffusivity values is performed. The results suggest the model employing Moss law of nucleation, modified NSC law of oxidation, and adopting a fractal dimension value of 2.0 and Schmidt number of 0.9 yields the simulation result that best agreed with experimental data.
Publisher: Informa UK Limited
Date: 13-12-2008
Publisher: Elsevier BV
Date: 11-2014
Publisher: MDPI AG
Date: 21-01-2023
DOI: 10.3390/MET13020212
Abstract: Single Snorkel Furnace (SSF) vacuum refining furnace is a novel external refining equipment for high clean steel production. RH is a molten steel refining technology developed by Rheinstahl-Heraeus company. Compared with the traditional RH furnace, the SSF furnace has the advantages of a simple structure, high refining efficiency, and low production cost. However, because the upward flow and the downward flow are in a single snorkel, the flow phenomenon is more complex than that in the RH device. Therefore, the gas–liquid two-phase flow law in SSF furnaces plays an important role in improving equipment efficiency and accurate control. In addition, the evolution and movement behavior of bubbles have an important influence on the two-phase flow. In this study, the Population Balance Model (PBM) model is employed to study the bubble properties, taking into account the effect of bubble coalescence and breakup on the flow field. The simulation results with this model are consistent with the experimental values, and the comparison with the results of the model without the PBM is revealed to be closer with less error. The results show that with the PBM model the flow field is more homogeneously distributed, the flow velocity is more stable, and the area distribution of the upward flow and downward flow in the snorkel is more symmetrical. In the case of this study, as the fluid level rises, the bubble diameter will increase due to the decrease in hydrostatic pressure.
Publisher: SAGE Publications
Date: 06-2009
DOI: 10.1260/175748209789563928
Abstract: In this article, we present a review of the state-of-the-art population balance modelling techniques that have been adopted to describe the phenomenological nature of isothermal bubbly flows. The main focus of the review can be broadly classified into three categories: (i) Numerical approaches or solution algorithms of the PBE (ii) Applications of the PBE in practical gas-liquid multiphase problems and (iii) Possible aspects of the future development in population balance modelling. For the first category, details of solution algorithms based on both method of moment (MOM) and discrete class method (CM) that have been proposed in the literature are provided. Advantages and drawbacks of both approaches are also discussed from the theoretical and practical viewpoints. For the second category, applications of existing population balance models in practical multiphase problems that have been proposed in the literature are summarized. Selected existing mathematical closures for modelling the “birth” and “death” rate of bubbles in gas-liquid bubbly flows are introduced. Particular attention is devoted to assess the capability of some selected models in predicting bubbly flow conditions through detail validation studies against experimental data. These studies demonstrate that good agreement can be achieved by the present model by comparing the predicted results against measured data with regards to the radial distribution of void fraction and sauter mean bubble diameter. Finally, weaknesses and limitations of the existing models are revealed are suggestions for further development are discussed. Emerging topics for future population balance studies are provided as to complete the aspect of population balance modelling.
Publisher: Elsevier BV
Date: 08-2021
Publisher: AIP
Date: 2010
DOI: 10.1063/1.3366467
Publisher: Elsevier BV
Date: 02-2011
Publisher: Springer Science and Business Media LLC
Date: 12-2010
DOI: 10.1007/S13246-010-0050-4
Abstract: Numerical simulation is performed to demonstrate that hemodynamic factors are significant determinants for the development of a vascular pathology. Experimental measurements by particle image velocimetry are carried out to validate the credibility of the computational approach. We present a study for determining complex flow structures using the case of an anatomically realistic carotid bifurcation model that is reconstructed from medical imaging. A transparent silicone replica of the artery is developed for in-vitro flow measurement. The dynamic behaviours of blood through the vascular structure based on the numerical and experimental approaches show good agreement.
Publisher: Elsevier BV
Date: 05-2022
Publisher: Elsevier
Date: 2018
Publisher: Elsevier BV
Date: 06-2023
Publisher: Elsevier BV
Date: 12-2011
Publisher: Elsevier BV
Date: 07-2008
Publisher: SAGE Publications
Date: 03-2012
Abstract: Two-fluid modeling approach is considered as one of the most practical and accurate macroscopic formulation of handling bubbly flow systems. Nevertheless, in order to rigorously account for bubble-bubble interactions, the population balance equation (PBE) must be solved alongside with the continuity and momentum balance equations. Class method typified by the MUltiple SIze Group (MUSIG) model appears to be one of the most direct methods to solve the PBE using a finite series of discrete classes. In this paper, an alternative approach based on the direct quadrature method of moments (DQMOM) is investigated. In contrast to MUSIG model which requires a large number of classes to resolve the bubble distribution, the main advantage of DQMOM is that the number of moments to be solved is generally very small. Validation and assessment of the two population balance models are carried out against measurements of vertical bubbly flows for a range of flow conditions. Based on the present study, preliminary computed results have been found to compare very well against the experimental data as well as the numerical results predicted through the MUSIG model.
Publisher: Elsevier BV
Date: 11-2005
Publisher: Elsevier BV
Date: 03-2016
Publisher: MDPI AG
Date: 04-01-2022
DOI: 10.3390/MOLECULES27010292
Abstract: Building polymers implemented into building panels and exterior façades have been determined as the major contributor to severe fire incidents, including the 2017 Grenfell Tower fire incident. To gain a deeper understanding of the pyrolysis process of these polymer composites, this work proposes a multi-scale modelling framework comprising of applying the kinetics parameters and detailed pyrolysis gas volatiles (parent combustion fuel and key precursor species) extracted from Molecular Dynamics models to a macro-scale Computational Fluid Dynamics fire model. The modelling framework was tested for pure and flame-retardant polyethylene systems. Based on the modelling results, the chemical distribution of the fully decomposed chemical compounds was realised for the selected polymers. Subsequently, the identified gas volatiles from solid to gas phases were applied as the parent fuel in the detailed chemical kinetics combustion model for enhanced predictions of toxic gas, charring, and smoke particulate predictions. The results demonstrate the potential application of the developed model in the simulation of different polymer materials without substantial prior knowledge of the thermal degradation properties from costly experiments.
Publisher: ISEC Press
Date: 11-2020
DOI: 10.14455/ISEC.2020.7(2).CON-31
Abstract: Applying Virtual Reality (VR) in construction professional training has been advocated as an effective method to improve learner’s cognition. However, there has been a lack of a systematic approach in VR-based training in the construction context. This study aims to develop a framework to institutionalize VR-based construction professional training design. Virtual Generation and Experience Road Map (VGERM) was adopted in the development of the mobile VR app for use in teaching substructure in an undergraduate construction technology course. A mobile VR app was developed by using a Unity-based platform, namely EduVenture. Procedures of the VR app development were articulated with an aim to demonstrate how the proposed framework can be utilized in fostering knowledge and skills transfer. Feedback of the users was collected through the Course Experience Survey. Findings of this study help gain a better understanding of the key areas to foster the benefits of VR for efficient use within professional construction training.
Publisher: MDPI AG
Date: 09-04-2019
DOI: 10.3390/APP9071476
Abstract: Nanofluids can be considered as engineered colloidal suspensions of nanometer-sized particles in a base fluid of water, ethylene glycol, or oil [...]
Publisher: Elsevier BV
Date: 05-2016
Publisher: Elsevier BV
Date: 2018
Publisher: MDPI AG
Date: 15-05-2020
DOI: 10.3390/APP10103428
Abstract: The fundamental flow structure and temperature distribution of small-scale fire whirls, including tangential and axial velocities, temperature variation, and air entrainment in the lower boundary layer, were successfully captured using a generic fire field model with large eddy simulation (LES) turbulence closure. Numerical predictions were validated thoroughly against two small-scale experimental measurements, where detailed temperature and velocity distributions were recorded. Good agreement between numerical and experimental results was achieved. Normalization was also performed to compare the numerical predictions with the empirical correlations by Lei et al. (2015) developed from medium-scale fire whirl measurements. The transient development stages of small-scale fire whirls and the impact of air entrainment on the stability of the fire whirls were also investigated based on the validated numerical results. The numerical validations showed the potential of the current LES fire field model in capturing the dynamic behaviour of the fire whirl plume and performing a quantitative analysis on its onset criteria and combustion dynamics in future.
Publisher: SAGE Publications
Date: 25-12-2016
Abstract: In order to accurately predict the thermal hydraulic of two-phase gas–liquid flows with heat and mass transfer, special numerical considerations are required to capture the underlying physics: characteristics of the heat transfer and bubble dynamics taking place near the heated wall and the evolution of the bubble size distribution caused by the coalescence, break-up, and condensation processes in the bulk subcooled liquid. The evolution of the bubble size distribution is largely driven by the bubble coalescence and break-up mechanisms. In this paper, a numerical assessment on the performance of six different bubble coalescence and break-up kernels is carried out to investigate the bubble size distribution and its impact on local hydrodynamics. The resultant bubble size distributions are compared to achieve a better insight of the prediction mechanisms. Also, the void fraction, bubble Sauter mean diameter, and interfacial area concentration profiles are compared against the experimental data to ensure the validity of the models applied.
Publisher: MDPI AG
Date: 04-2019
DOI: 10.3390/MET9040400
Abstract: With the demand of high-quality steel and miniaturization of the special steel production, single snorkel vacuum refining process has been widely concerned in China recently, because of its simple structure and good performance of degassing and decarburization. In this study, a water model experimental system and a three-dimensional mathematical model based on two-fluid multiphase flow model have been built to analyze the refining efficiency limitation of the single snorkel vacuum refining furnace from the flow pattern and gas distribution. The results showed that there is a limited gas flow rate, and beyond this flow rate the gas column deviates to the wall and the redundant bubbles escape from the free surface, which will not further improve the refining efficiency and will lead to the erosion of the snorkel. In this case, the limited flow rate is 900 NL/h. Furthermore, the fluctuation of the free surface and the different structural parameters have significant effects on the flow field in single-snorkel vacuum refining furnace (SSF).
Publisher: Elsevier BV
Date: 06-2017
Publisher: AIP
Date: 2012
DOI: 10.1063/1.4756076
Publisher: AIP
Date: 2010
DOI: 10.1063/1.3452294
Publisher: Elsevier BV
Date: 10-2016
Publisher: Wildlife Disease Association
Date: 02-07-2020
DOI: 10.7589/2019-05-120
Publisher: Elsevier BV
Date: 12-2009
Publisher: Elsevier BV
Date: 02-2020
Publisher: SAGE Publications
Date: 09-2014
Publisher: SAGE Publications
Date: 2014
DOI: 10.1155/2014/792050
Start Date: 2014
End Date: 2015
Funder: National Natural Science Foundation of China
View Funded ActivityStart Date: 2018
End Date: 2021
Funder: Australian Renewable Energy Agency
View Funded ActivityStart Date: 2015
End Date: 2017
Funder: Australian Research Council
View Funded ActivityStart Date: 2008
End Date: 2010
Funder: Australian Research Council
View Funded ActivityStart Date: 2013
End Date: 2016
Funder: Australian Research Council
View Funded ActivityStart Date: 2013
End Date: 2015
Funder: Australian Research Council
View Funded ActivityStart Date: 2016
End Date: 2018
Funder: Australian Research Council
View Funded ActivityStart Date: 06-2014
End Date: 06-2019
Amount: $205,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2015
End Date: 06-2016
Amount: $152,436.00
Funder: Australian Research Council
View Funded ActivityStart Date: 01-2008
End Date: 07-2011
Amount: $235,944.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2013
End Date: 12-2017
Amount: $315,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2018
End Date: 07-2023
Amount: $4,272,072.00
Funder: Australian Research Council
View Funded Activity