ORCID Profile
0000-0002-4553-9697
Current Organisation
NIWA - The National Institute of Water and Atmospheric Research Ltd.
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Publisher: Society of Economic Geologists
Date: 15-04-2015
Publisher: American Geophysical Union (AGU)
Date: 07-2012
DOI: 10.1029/2012JB009163
Publisher: Elsevier BV
Date: 2019
Publisher: American Geophysical Union (AGU)
Date: 2012
DOI: 10.1029/2011JB008550
Publisher: Ubiquity Press, Ltd.
Date: 2023
DOI: 10.5334/DSJ-2023-005
Publisher: Elsevier BV
Date: 06-2015
Publisher: Oxford University Press (OUP)
Date: 12-2015
Publisher: Public Library of Science (PLoS)
Date: 19-04-2022
DOI: 10.1371/JOURNAL.PNTD.0010275
Abstract: The epidemiology of trachoma in several Pacific Islands differs from other endemic settings, in that there is a high prevalence of clinical signs of trachoma, particularly trachomatous inflammation—follicular (TF), but few cases of trichiasis and limited evidence of ocular chlamydial infection. This so-called “Pacific enigma” has led to uncertainty regarding the appropriate public health response. In 2019 alongside Nauru’s national trachoma population survey, we performed bacteriological and serological assessments of children to better understand the typology of trachoma and to determine whether there is a need for trachoma interventions. We used two-stage cluster s ling, examining residents aged ≥1 year and collecting household-level water, sanitation, and hygiene (WASH) variables. Children aged 1–9 years provided conjunctival swabs and finger-prick dried blood spots to investigate the presence of Chlamydia trachomatis nucleic acid and anti-Pgp3 antibodies, respectively. In 818 participants aged 1–9 years, the age-adjusted TF prevalence was 21.8% (95% CI 15.2–26.2%) ocular C . trachomatis prevalence was 34.5% (95% CI 30.6–38.9), and anti-Pgp3 antibody prevalence was 32.1% (95% CI 28.4%–36.3%). The age- and gender-adjusted prevalence of trichiasis in ≥15-year-olds was 0.3% (95% CI 0.00–0.85), but no in idual with trichiasis had trachomatous scarring (TS). Multivariable analysis showed an association between age and both TF (OR per year of age 1.3 [95% CI 1.2–1.4]) and anti-Pgp3 positivity (OR 1.2 [95% CI 1.2–1.3]). There were high rates of access to water and sanitation and no WASH variable was associated with the presence of TF. TF, nucleic acid, and age-specific antibody prevalence collectively indicate that high levels of C . trachomatis transmission among children present a high risk of ocular damage due to trachoma. The absence of trichiasis with trachomatous scarring suggest a relatively recent increase in transmission intensity.
Publisher: Society of Economic Geologists
Date: 30-09-2013
Publisher: Society of Economic Geologists
Date: 04-11-2013
Location: Australia
Location: New Zealand
Location: Australia
Location: New Zealand
Location: No location found
No related grants have been discovered for Jesse Robertson.