ORCID Profile
0000-0002-8298-1417
Current Organisation
University of Leeds
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Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C8RE00211H
Abstract: A continuous-flow platform enables rapid kinetic profiling and accelerated production of block copolymer nano-objects via RAFT aqueous dispersion polymerization.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1RA01222C
Abstract: Mg(OH) 2 suspensions were floated utilising sodium dodecyl sulphate (SDS) sodium lauroyl isethionate (SLI) collectors, for rapid dewatering of radwaste suspensions.
Publisher: Elsevier BV
Date: 10-2023
Publisher: Elsevier BV
Date: 02-2021
Publisher: Royal Society of Chemistry (RSC)
Date: 2014
DOI: 10.1039/C4PY00856A
Abstract: Tuning the thermo-responsive behavior of statistical diblock copolymer worms.
Publisher: Royal Society of Chemistry (RSC)
Date: 2011
DOI: 10.1039/C1SM05771E
Publisher: American Chemical Society (ACS)
Date: 23-02-2011
DOI: 10.1021/NN102455Z
Abstract: Nature has the exquisite ability to design specific surface patterns and topologies on both the macro- and nanolength scales that relate to precise functions. Following a biomimetic approach, we have engineered fully synthetic nanoparticles that are able to self-organize their surface into controlled domains. We focused on polymeric vesicles or "polymersomes" enclosed membranes formed via self-assembly of hiphilic block copolymers in water. Exploiting the intrinsic thermodynamic tendency of dissimilar polymers to undergo phase separation, we mixed different vesicle-forming block copolymers in various proportions in order to obtain a wide range of polymersomes with differing surface domains. Using a combination of confocal laser scanning microscopy studies of micrometer-sized polymersomes, and electron microscopy, atomic force microscopy, and fluorescence spectroscopy on nanometer-sized polymersomes, we find that the domains exhibit similar shapes on both the micro- and nanolength scales, with dimensions that are linearly proportional to the vesicle diameter. Finally, we demonstrate that such control over the surface "patchiness" of these polymersomes determines their cell internalization kinetics for live cells.
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Nicholas Warren.