ORCID Profile
0000-0002-2139-1616
Current Organisation
University of Eastern Finland
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Publisher: Inderscience Publishers
Date: 2018
Publisher: Elsevier BV
Date: 11-2022
Publisher: Springer Science and Business Media LLC
Date: 27-06-2019
Publisher: Springer Science and Business Media LLC
Date: 03-07-2019
Publisher: Emerald
Date: 30-09-2021
DOI: 10.1108/IJEBR-05-2021-0401
Abstract: Communicating the identity of a family business generates positive results in consumer response. The paper aims to understanding how the efficient transmission of family identity can influence consumer behavior is essential for designing family firms' marketing communication strategies. An experimental study based on the eye-tracking technique was designed to determine how attention to (familiar vs non-familiar) visual stimuli on a website influences consumer recognition of a family firm status and how it influences consumer behavior. A s le of 212 in iduals was exposed to (simulated) websites of family and non-family firms in the hospitality industry to capture information about their eye movements and measure visual attention to specific stimuli that communicated family identity. Visual attention has a direct and positive influence on recognizing family firm's identity (FFI). Through FFI, visual attention has an indirect positive effect on trust in the company and attitude toward the brand (BraAtt). Trust in a firm positively affects purchase intention (PurInt). It is known that consumers can perceive a FFI however, there is no study on the sensory mechanisms operating in consumers' perceptions of family identity. The study contributes to understanding how consumers can perceive a FFI. This study proposes a novel method for evaluating consumer responses by transmitting family business identity on digital platforms.
Publisher: Springer Science and Business Media LLC
Date: 05-01-2021
Publisher: Emerald
Date: 05-03-2018
DOI: 10.1108/JEEE-07-2017-0052
Abstract: The purpose of this paper is to provide a tool for the integration of knowledge and the development of students’ capacities for analysis in the area of strategic management of companies. Mall Connection is a Chilean company that has developed mainly in the business of the commercialization of technological devices and their accessories. From this base, it has constructed a portfolio of related business and currently has expansion into neighbouring countries as one of its most important challenges. The case has been developed from primary sources of information, in-depth interviews with the management team of the company and secondary information obtained mainly from the Passport Euromonitor database. This information was processed, analysed and presented in the document so as to give support to the learning outcomes defined in the teaching notes. The breadth of the case offers flexibility in its application in corporate strategy and business courses. It allows external and internal competitive analysis of the strategy of the company. One central aspect is that it requires students to integrate the theory learnt in their courses with the practical experience described in the case to propose answers to the questions asked. The case is of great value in motivating the learning in MBA students and in courses of business strategy at undergraduate level. It is an original case that allows students to know experiences of entrepreneurship and strategic management in a Latin American context.
Publisher: MDPI AG
Date: 30-12-2021
Abstract: Human cerebral organoids, derived from induced pluripotent stem cells, offer a unique in vitro research window to the development of the cerebral cortex. However, a key player in the developing brain, the microglia, do not natively emerge in cerebral organoids. Here we show that erythromyeloid progenitors (EMPs), differentiated from induced pluripotent stem cells, migrate to cerebral organoids, and mature into microglia-like cells and interact with synaptic material. Patch-cl electrophysiological recordings show that the microglia-like population supported the emergence of more mature and ersified neuronal phenotypes displaying repetitive firing of action potentials, low-threshold spikes and synaptic activity, while multielectrode array recordings revealed spontaneous bursting activity and increased power of gamma-band oscillations upon pharmacological challenge with NMDA. To conclude, microglia-like cells within the organoids promote neuronal and network maturation and recapitulate some aspects of microglia-neuron co-development in vivo, indicating that cerebral organoids could be a useful biorealistic human in vitro platform for studying microglia-neuron interactions.
Publisher: Springer Science and Business Media LLC
Date: 08-01-2020
Publisher: Elsevier BV
Date: 08-2019
Publisher: Cold Spring Harbor Laboratory
Date: 09-12-2020
DOI: 10.1101/2020.12.08.416388
Abstract: Human stem cell-derived brain organoids provide a physiologically relevant in vitro 3D brain model for studies of neurological development that are unique to the human nervous system. Prior studies have reported protocols that support the maturation of microglia from mesodermal progenitors leading to innately developing microglia within the organoids. However, although microglia are known to support neuronal development in rodents, none of the previous studies have reported what is the impact of microglia on neuronal growth and maturation in human brain organoids. Here we show that incorporating microglial progenitors into the developing organoid supports neuronal maturation, the emergence of neurons capable of firing repetitive action potentials and the appearance of synaptic and neuronal bursting activity. Immunocompetent organoids enable experimental strategies for interrogating fundamental questions on microglial and neuronal ersity and function during human brain development.
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Antonios Dougalis.