ORCID Profile
0000-0002-4837-4963
Current Organisations
Universiti Teknologi MARA
,
University of Queensland
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Publisher: Elsevier BV
Date: 15-12-2008
Publisher: Enviro Research Publishers
Date: 20-12-2022
Abstract: Purple Sweet Potato (PSP) in Malaysia is an abandoned crop. Even though it has various health benefits and nutritional values, consumers, especially Malaysians, still lack purple sweet potato consumption. It has a high dietary fibre content, a low glycemic index, and contains proteins, minerals, polyphenols, and anthocyanin. The National Health Morbidity Survey (Malaysia) in 2019 reported that 94% of Malaysian adults lack fiber consumption in their dietary patterns. As a result, it may become an alternative crop for in iduals who consume less nutrients and fibre as a result of dietary choices and health issues. This one-of-a-kind crop also contains anti-oxidative, hepatoprotective, anti-inflammatory, anti-tumor, anti-diabetic, anti-microbial, anti-obesity, and anti-aging qualities. Due to the lack of a commercial food product based on this crop, it has become an unpopular crop among Malaysians. Purple sweet potato makes only a few Malaysian sweets and traditional snacks. Nonetheless, Malaysian customers continue to ignore it. Thus, Purple Sweet Potato Cracker was made, and a proximate analysis was conducted to examine its physicochemical content. It was found that the newly developed PSP crackers were high in fiber, vitamins, and minerals, as well as in calcium (1332.08 mg/kg) and contained anthocyanins of 6.68 mg/L. Besides that, this special cracker is free from food preservatives without coloring agents and additives. The processing of Purple Sweet Potato Cracker carries important features for small-medium entrepreneurs, which will contribute to the Malaysian economy perspectives, as it has a good potential to be marketed in domestic and international commercial food outlets.
Publisher: MDPI AG
Date: 10-08-2022
Abstract: Coronavirus disease 2019 (COVID-19) is an infectious disease with approximately 517 million confirmed cases, with the average number of cases revealing that patients recover immediately without hospitalization. However, several other cases found that patients still experience various symptoms after 3–12 weeks, which is known as a long COVID syndrome. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can activate nuclear factor kappa beta (NF-κβ) and unbind the nuclear factor erythroid 2-related factor 2 (Nrf2) with Kelch-like ECH-associated protein 1 (Keap1), causing inhibition of Nrf2, which has an important role in antioxidant response and redox homeostasis. Disrupting the Keap1–Nrf2 pathway enhances Nrf2 activity, and has been identified as a vital approach for the prevention of oxidative stress and inflammation. Hence, natural antioxidants from various sources have been identified as a promising strategy to prevent oxidative stress, which plays a role in reducing the long COVID-19 symptoms. Oxygen-rich natural antioxidant compounds provide an effective Nrf2 activation effect that interact with the conserved amino acid residues in the Keap1-binding pocket, such as Ser602, Ser363, Ser508, and Ser555. In this review, the benefits of various natural antioxidant compounds that can modulate the Nrf2 signaling pathway, which is critical in reducing and curing long COVID-19, are highlighted and discussed.
Publisher: Wiley
Date: 14-03-2008
DOI: 10.1002/JSFA.3186
Publisher: Springer Singapore
Date: 2020
Publisher: Elsevier BV
Date: 08-2009
Publisher: University of Queensland Library
Date: 2019
DOI: 10.14264/UQL.2020.83
Publisher: Emerald
Date: 17-08-2020
Abstract: The purpose of this paper is to assess the value of websites accessible to patients looking for Web-based information regarding hypertension management. A cross-sectional research was carried out by finding out Malay and English language websites about hypertension. For this purpose, the keywords “hypertension and treatment” were entered on the Yahoo, Google, Ask.com, Bing and DuckDuckGo search engines, and the first five pages of the results obtained were inspected. The DISCERN tool was deployed for evaluating the quality of information. The actionability and understandability were assessed through the Patient Education Materials Assessment Tool (PEMAT). Eight assessors were asked to assess and grade the involved websites. Of the 216 websites, eight (4.0%) conformed to the inclusion norms. All websites were classified into private, 4 (50%) government, 2 (25%) and personal, 2 (25%). The general rating of the eight websites was good (mean 51.6 ± 8.2 on a 75-point scale) however, half of the websites were rated as fair (mean 45.3 ± 3.1 on a 75-point scale). All websites conformed to the standard score of ≥70% for understandability (mean 76.1 ± 11.4), but none for actionability (mean 52.8 ± 13.9). Analysis of variance indicated there was no statistical difference with regards to quality ( p = 0.525), understandability ( p = 0.484) and actionability ( p = 0.188) among the three website sets. Considering the surplus of websites dedicated to information on hypertension, an independent assessment of the quality of these websites will be advantageous. Patients should be rendered high understandability, quality and actionability to evade deceptive online information.
Publisher: Elsevier BV
Date: 2006
Publisher: Elsevier BV
Date: 08-2015
Publisher: Rynnye Lyan Resources
Date: 28-02-2023
DOI: 10.26656/FR.2017.7(1).660
Abstract: The emergence of COVID-19 had affected people in terms of their physical activity and nutritional changes which may increase the risk of various non-communicable diseases (NCD) among them. This study aimed to identify the physical activity level, nutritional changes, and perceived barriers to engage physical activity among students of UiTM Selangor, Puncak Alam C us during the Movement Control Order (MCO) in Malaysia. A total of 234 students aged 18-24 years old were chosen to participate in this study by using convenience s ling. The International Physical Activity Questionnaire (IPAQ), Physical Activity Resource Assessment (PARA), and adapted questionnaire from the Ministry of Health (MOH) Malaysia were used in this study. Findings reveal that students were able to engage in physical activity level during the pandemic period which required them to be quarantined. Moreover, there was an increase in the frequency of healthy eating behaviour as well as unhealthy eating behaviour during MCO.
Publisher: Emerald
Date: 04-2004
DOI: 10.1108/00346650410529005
Abstract: This study was aimed to estimate and compare the contents of protein and amino acids in raw, boiled and fried fishes of Indian mackerel “kembong” ( Rastrelliger kanagurta ), sardine ( Sardina pilchardus ), red tilapia ( Oreochromis mossambicusx ) and black tilapia ( Oreochromis mossambicus ). Protein contents of raw mackerel, sardine, red and black tilapia were 8.1±0.0, 8.4±0.1, 9.6±0.4 and 9.0±0.0 percent, respectively. In a boiled fish, the protein contents were 7.9±0.1, 7.7±0.0, 7.5±0.1 and 8.9±0.1 percent, respectively, and for a fried fish the values were 8.6±0.5, 8.9±0.1, 9.1±0.2 and 8.4±0.0 percent, respectively. It was found that there was a significant difference ( p .01) in the protein content of the raw fish compared to the heat‐treated ones for all the fishes. The study detected 17 components of essential amino acids (lysine, histidine, threonine, valine, methionine, leucine, isoleucine and phenylalanine) and non‐essential amino acids (arginine, aspartic acid, serine, glutamic acid, proline, glycine, alanine, cystein and tyrosine) in all the fishes. There was no significant difference in amino acids content among the boiled and fried fishes. In conclusion, heat treatment for five minutes in boiling water (100°C) and frying for three minutes in palm oil (160°C) did not alter the quality of protein in all the fishes studied.
Publisher: MDPI AG
Date: 30-01-2022
DOI: 10.3390/MOLECULES27030949
Abstract: Neuraminidase (NA) is an enzyme that prevents virions from aggregating within the host cell and promotes cell-to-cell spread by cleaving glycosidic linkages to sialic acid. The best-known neuraminidase is the viral neuraminidase, which present in the influenza virus. Thus, the development of anti-influenza drugs that inhibit NA has emerged as an important and intriguing approach in the treatment of influenza. Garcinia atroviridis L. (GA) dried fruits (GAF) are used commercially as seasoning and in beverages. The main objective of this study was to identify a new potential neuraminidase inhibitor from GA. A bioassay-guided fractionation method was applied to obtain the bioactive compounds leading to the identification of garcinia acid and naringenin. In an enzyme inhibition study, garcinia acid demonstrated the highest activity when compared to naringenin. Garcinia acid had the highest activity, with an IC50 of 17.34–17.53 µg/mL or 91.22–92.21 µM against Clostridium perfringens-NA, and 56.71–57.85 µg/mL or 298.32–304.31 µM against H1N1-NA. Based on molecular docking results, garcinia acid interacted with the triad arginine residues (Arg118, Arg292, and Arg371) of the viral neuraminidase, implying that this compound has the potential to act as a NA enzyme inhibitor.
Publisher: International Society for Horticultural Science (ISHS)
Date: 12-2015
Publisher: MDPI AG
Date: 24-07-2023
Abstract: This study aims to provide an overview of the compounds found in sweet potato (Ipomoea batatas) that contribute to its anti-diabetic activity and the mechanisms by which they act. A comprehensive literature search was conducted using electronic databases, such as PubMed, Scopus, and Science Direct, with specific search terms and Boolean operators. A total of 269 articles were initially retrieved, but after applying inclusion and exclusion criteria only 28 articles were selected for further review. Among the findings, four varieties of sweet potato were identified as having potential anti-diabetic properties. Phenolic acids, flavonols, flavanones, and anthocyanidins are responsible for the anti-diabetic activity of sweet potatoes. The anti-diabetic mechanism of sweet potatoes was determined using a combination of components with multi-target actions. The results of these studies provide evidence that Ipomoea batatas is effective in the treatment of type 2 diabetes.
No related grants have been discovered for Emmy Hainida Khairul Ikram.