ORCID Profile
0000-0002-4231-8215
Current Organisation
University of Miami
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Publisher: Elsevier BV
Date: 08-2021
Publisher: Elsevier BV
Date: 2021
Publisher: CRC Press
Date: 17-02-2017
Publisher: Elsevier BV
Date: 08-2012
Publisher: Optica Publishing Group
Date: 24-07-2018
DOI: 10.1364/BOE.9.003834
Publisher: Optica Publishing Group
Date: 06-10-2021
DOI: 10.1364/BOE.435127
Abstract: We have combined an anterior segment (AS) optical coherence tomography (OCT) system and a wavefront-based aberrometer with an approach that senses ocular wavefront aberrations using the OCT beam. Temporal interlacing of the OCT and aberrometer channels allows for OCT images and refractive error measurements to be acquired continuously and in real-time. The system measures refractive error with accuracy and precision comparable to that of clinical autorefractors. The proposed approach provides a compact modular design that is suitable for integrating OCT and wavefront-based autorefraction within the optical head of the ophthalmic surgical microscope for guiding cataract surgery or table-top devices for simultaneous autorefraction and ocular biometry.
Publisher: Elsevier BV
Date: 04-2021
Publisher: Elsevier BV
Date: 07-2011
Publisher: Association for Research in Vision and Ophthalmology (ARVO)
Date: 15-04-2020
DOI: 10.1167/IOVS.61.4.11
Publisher: Optica Publishing Group
Date: 20-07-2021
DOI: 10.1364/BOE.427286
Abstract: We acquired 1325 nm OCT images of the sclera and ciliary muscle of human subjects. The attenuation coefficients of the sclera and ciliary muscle were determined from a curve fit of the average intensity profile of about 100 A-lines in a region of interest after correction for the effect of beam geometry, using a single scattering model. The average scleral attenuation coefficient was 4.13 ± 1.42 mm -1 with an age-related decrease that was near the threshold for statistical significance (p = 0.053). The average ciliary muscle attenuation coefficient was 1.72 ± 0.88 mm -1 , but this value may be an underestimation due to contributions from multiple scattering. Overall, the results suggest that inter-in idual variations in scleral attenuation contribute to variability in the quality of transscleral OCT images of the ciliary muscle and the outcome of transscleral laser therapies.
Publisher: Optica Publishing Group
Date: 06-09-2022
DOI: 10.1364/BOE.464121
Abstract: The lens of the eye has a refractive index gradient that changes as the lens grows throughout life. These changes play a key role in the optics of the eye. Yet, the lens is generally simulated using a homogeneous model with an equivalent index that does not accurately represent the gradient. We present an analytical paraxial model of the gradient lens of the eye that gives the direct relation between refractive index distribution and paraxial characteristics. The model accurately simulates the changes in lens power with age and accommodation. It predicts that a decrease in equivalent index with age is associated with a flattening of the axial refractive index profile and that changes in lens power with accommodation are due primarily to changes in the axial variation of the iso-indicial curvature, consistent with Gullstrand’s intracapsular theory of accommodation. The iso-indicial curvature gradient causes a shift of the principal planes compared to the homogeneous equivalent model. This shift introduces a clinically significant error in eye models that implement a homogenous lens. Our gradient lens model can be used in eye models to better predict the optics of the eye and the changes with age and accommodation.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 09-2022
DOI: 10.1097/J.JCRS.0000000000000934
Abstract: To determine whether patient-customized paraxial eye models that do not rely on exact ray tracing and do not consider aberrations can accurately predict pseudophakic refraction. Bascom Palmer Eye Institute, Miami, Florida. Prospective study. Cataract surgery patients with and without a history of refractive surgery were included. Manifest refraction, corneal biometry, and extended-depth optical coherence tomography (OCT) imaging were performed at least 1 month postoperatively. Corneal and OCT biometry were used to create paraxial eye models. The pseudophakic refraction simulated using the eye model was compared with measured refraction to calculate prediction error. 49 eyes of 33 patients were analyzed, of which 12 eyes from 9 patients had previous refractive surgery. In eyes without a history of refractive surgery, the mean prediction error was 0.08 ± 0.33 diopters (D), ranging from −0.56 to 0.79 D, and the mean absolute error was 0.27 ± 0.21 D. 31 eyes were within ±0.5 D, and 36 eyes were within ±0.75 D. In eyes with previous refractive surgery, the mean prediction error was −0.44 ± 0.58 D, ranging from −1.42 to 0.32 D, and the mean absolute error was 0.56 ± 0.46 D. 7 of 12 eyes were within ±0.5 D, 8 within ±0.75 D, and 10 within ±1 D. All eyes were within ±1.5 D. Accurate calculation of refraction in postcataract surgery patients can be performed using paraxial optics. Measurement uncertainties in ocular biometry are a primary source of residual prediction error.
No related grants have been discovered for Fabrice Manns.