ORCID Profile
0000-0003-4437-3784
Current Organisations
The University of Auckland
,
Chitkara University
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Publisher: The Electrochemical Society
Date: 24-04-2022
Abstract: Amblyopia interferes in the critical period of visual development among children. Due to the limitations of conventional management of patching therapy, in the recent decade digital screen based binocular vision therapy was introduced. We aimed to study the awareness and attitude of eye care practitioners towards digital screen based binocular vision therapy in management of amblyopia. The study has been conducted by constructing and validating a questionnaire. The questionnaire was validated through a pilot study. Around 104 eye care practitioners responded to the survey, showing 96% of the eye care practitioners’ awareness towards refractive correction as the first line of management for amblyopia. A high number of respondents (83%) were aware of prescribing computer-based video games for amblyopia therapy in the clinical practice. 'The visual function improvement is very much feasible with digital screen based binocular vision therapy’ was the opinion of 55% (n=52) of eye care practitioners.
Publisher: Medknow
Date: 2021
Publisher: SynthesisHub Advance Scientific Research
Date: 2020
DOI: 10.31838/EJMCM
Publisher: Medknow
Date: 05-2023
Publisher: Elsevier BV
Date: 04-2012
DOI: 10.1016/J.CLAE.2011.08.008
Abstract: To establish if sodium fluorescein (SFL) dye accumulation within intercellular spaces on the ocular surface contributes to the appearance of superficial punctate corneal staining. Thirteen subjects bilaterally wore PureVision™ lenses that had been pre-soaked in ReNu MultiPlus® multipurpose solution. After 1h of lens wear, corneal staining with SFL was assessed using a standard slit-l technique. Participants who presented with bilateral, corneal staining were selected for further evaluation. A randomly selected eye was rinsed with saline three times. Fellow eyes (control) received no rinsing. After each rinse, the appearance of SFL staining was recorded without any further instillation of the dye. To eliminate any confounding effects of staining due to residual fluorescein in the tear menisci, corneal staining was induced in freshly excised, isolated, rabbit eyes by topical administration of 0.001% PHMB and staining, rinsing and grading were performed as above. Nine out of 13 subjects presented with bilateral diffuse corneal staining (mean grade±SD: 2.4±0.7). The mean staining grades in test and control eyes respectively after each of the three rinses were (1) 2.41±0.41, 2.25±0.69 (p=0.9) (2) 2.34±0.79, 2.1±0.83 (p=0.8) and (3) 1.71±0.65, 1.60±0.79 (p=0.6) there was no significant reduction in staining with rinsing (p>0.05) and no difference was observed between test and control eyes at any s ling-point. Similar observations made in ex vivo rabbit eyes replicated these results. Pooling or accumulation of SFL solution within intercellular spaces does not appear to contribute to the appearance of superficial micropunctate corneal staining.
Publisher: Elsevier BV
Date: 06-2014
DOI: 10.1016/J.CLAE.2013.11.003
Abstract: To evaluate the physiological status of corneal epithelial cells exhibiting fluorescein staining. Fluorescein staining properties of corneal epithelial cells under normal and stressed conditions were studied using cell-culture (human corneal limbal epithelial cells - HCLE) and organ-culture (rabbit) models. Stress stimuli comprised exposure to hypotonicity, hypertonicity, preservatives, scratch, and alkaline wounding. In addition to fluorescein, cells were stained with Hoechst-33342 (HO), Propidium-iodide (PI), and Annexin-V (AN-V) to identify live, dead and apoptotic cells. Clinical-slit-l and fluorescence confocal-microscopic (FCM) observations were performed. FCM images were quantified for fluorescence intensity using Image-J software. Healthy HCLE cells uniformly took up fluorescein to a moderate degree with a mean grey value of 62 ± 24 (mean ± SD) on a scale of 0-256 (no unit). Fluorescence levels similar to those observed prior to stress were associated with healthy cells. Apoptotic cells showed the highest fluorescence (138 ± 38). Dead cells showed minimal fluorescence (23 ± 7) that was similar to the background (20 ± 11, p>0.05). Observations in whole rabbit eyes were in general agreement with these cell culture findings. The clinical observation of corneal staining with fluorescein suggests the presence of epithelial cells that are undergoing apoptosis but does not indicate dead cells. Under in vitro or ex vivo conditions, healthy cells took up fluorescein at levels that were lower than those of apoptotic cells and thus, are not likely to be perceived as exhibiting staining during clinical observation. Sodium fluorescein may be considered as a probe for apoptotic epithelial cells.
Publisher: Elsevier BV
Date: 12-2011
Publisher: Elsevier BV
Date: 08-2010
DOI: 10.1016/J.CLAE.2010.02.004
Abstract: To evaluate the early phase time course of solution induced corneal staining. A double masked, single centred, prospective clinical trial was conducted. Twenty-five participants, either experienced or new contact lens wearers, participated in the study. Corneal staining response to short term use of ReNu MultiPlus Multipurpose Solution and PureVision silicon hydrogel contact lens with fluorescein was observed using standard techniques after 15, 30, 45, 60 and 120 min of lens wear and graded according to the IER scale. Measurements were carried out on separate days for each time point, in random order. Mean extent of staining was greater in test than in control eyes at all time points except baseline. In test eyes, the degree of staining increased successively at each time point after insertion, up to, but not beyond, 60 min. For those participants presenting with staining, maximum severity and frequency were both observed at 60 min and were significantly greater (p < 0.05) than at 15, 30, and 45 min. Solution induced corneal staining gradually increased after lens insertion to a maximum at 1h. This level was maintained until at least 2h post-insertion.
Publisher: Elsevier BV
Date: 12-2019
Publisher: Elsevier BV
Date: 07-2023
Publisher: Informa UK Limited
Date: 31-01-2022
DOI: 10.1080/09286586.2022.2032202
Abstract: To determine the prevalence of refractive error (RE) and associated risk factors for myopic refractive errors in children and young adults from the urban region of Hyderabad, South India. Four thousand sixty-five (4,065) participants aged 6-22 years were enrolled and examined in this cross-sectional study conducted from October 2013 to January 2015. Participants were enrolled from a random s le of schools and universities in regions representative of urban Hyderabad. RE was determined using cycloplegic autorefraction. The association of demographic factors such as age, gender, and socio-economic category (SEC) (low/mid/high) with myopia was explored with logistic regression with robust standard error. Of the total participants, 2,259 were children aged 6-15 years and 1,806 were adolescents and young adults aged 16-22 years. Overall prevalence of myopia, high myopia (≤ -5.00D and ≤ -6.00 D), hyperopia, emmetropia, and astigmatism was 29.8% (95% CI: 26.0% to 33.6%, n = 1,216), 2.9% (95% CI: 1.9% to 3.9%, n = 120), 1.1% (95%CI: 0.7% to 1.5%, n = 46), 14.7% (95% CI: 12.4% to 17.0%, n = 599), 46.9% (95% CI: 43.7% to 50.1%, n = 1913) and 8.6% (95% CI: 7.4% to 9.9%, n = 352) respectively. A strong correlation existed between age and prevalence of myopia (R Myopia was the most prevalent refractive error and increased with age in this urban population. More myopia was observed in schools of low SEC.
No related grants have been discovered for Kalika Bandamwar.