ORCID Profile
0000-0003-0420-0264
Current Organisations
University of the Sunshine Coast, Queensland
,
University of the Sunshine Coast
,
University of Queensland
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Canadian Science Publishing
Date: 05-2022
Abstract: This study investigated the acceptable accuracy of common body composition techniques compared with the reference 4-compartment (4C-R) model, which has not been investigated in a s le with erse characteristics, including age and sex. Techniques included components of the 4C-R model [dual-energy X-ray absorptiometry, air displacement plethysmography, deuterium dilution (DD)] and surrogate compartment models, which utilised bioelectrical impedance spectroscopy (BIS) rather than DD. Men and women (sex = 1:1, 18–85 years, n = 90) completed body composition testing under best-practice guidance. For measurement of in iduals, only the reference 3-compartment (3C-R) equation met acceptable error limits ( % error among in iduals) within the a priori cut-point (80%) for fat-free mass (FFM CV = 0.52%) and fat mass (FM CV = 1.61%). However, all investigated techniques reached equivalency to the 4C-R model for FFM on average (CV = 0.52–4.31%), but for FM only the 3C and 4C equations that included quantification of total body water (TBW) by DD or BIS reached equivalency overall (CV = 1.61–6.68%). Sex and age minimally influenced accuracy. Only the 3C-R or 4C-R equations are supported for acceptable in idual accuracy for both FFM and FM. For group estimates any investigated technique could be used with acceptable accuracy for FFM however, for FM, inclusion of TBW measurement within a compartment model is necessary. Novelty: Only the referent 3C and 4C models (including deuterium dilution) provide accurate body composition results that are acceptable for measurement of in iduals in the general population. For group estimates of lean mass in the general population, compartments models that include TBW must be used for accurate measurement.
Publisher: Elsevier BV
Date: 09-2023
Publisher: Springer Science and Business Media LLC
Date: 17-09-2021
DOI: 10.1007/S00198-021-06131-X
Abstract: To determine the pooled effect of exercise on the bone health of people diagnosed with cancer. Four electronic databases were systematically searched. Controlled trials that assessed the effect of exercise on the bone mineral density (BMD) or content (BMC) measured by dual-energy x-ray absorptiometry or peripheral quantitative computed tomography in people who had been diagnosed with cancer were included in the study. Random-effect meta-analyses of effect size (ES) were conducted. Sub-group analyses were performed to explore the influence of intervention duration, prescription and participant characteristics. Of 66 full-text articles screened, 22 studies, from 21 interventions, were included (primarily breast rostate cancer, s le range n = 36-498). When all interventions were grouped, a significant pooled ES was observed for exercise on hip (ES = 0.112, 95% CI: 0.026 to 0.198 p = 0.011) and lumbar spine BMD (ES = 0.269, 95% CI: 0.036 to 0.501 p = 0.024) compared to control. There was also an influence of sex, where females had greater improvements in hip (ES = 0.120, 95% CI: 0.017 to 0.223 p = 0.022) and spine BMD (ES = 0.415, 95% CI: 0.056 to 0.774 p = 0.23) compared to males. Overall, exercise regimens of studies included in this review appear to improve bone health at the hip and spine in people diagnosed with cancer. Sub-analyses suggest some influence of sex, where females had greater improvements in BMD compared to males. It is essential that future studies evaluate the dose-response of exercise training on bone health and create exercise protocols that better align with the laws of bone modelling to enhance osteogenic potential.
Publisher: University of Queensland Library
Date: 2021
DOI: 10.14264/80CB125
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 07-2020
Publisher: Springer Science and Business Media LLC
Date: 22-05-2023
DOI: 10.1007/S40279-023-01862-9
Abstract: Cancer-related pain is common and undertreated. Exercise is known to have a pain-relieving effect in non-cancer pain. This systematic review aimed to evaluate (1) the effect of exercise on cancer-related pain in all cancers, and (2) whether the effect of exercise differed according to exercise mode, degree of supervision, intervention duration and timing (during or after cancer treatment), pain types, measurement tool and cancer type. Electronic searches were undertaken in six databases to identify exercise studies evaluating pain in people with cancer, published prior to 11 January 2023. All stages of screening and data extraction were conducted independently by two authors. The Cochrane risk of bias tool for randomised trials (RoB 2) was used and overall strength of evidence was assessed using the GRADE approach. Meta-analyses were performed overall and by study design, exercise intervention and pain characteristics. In total, 71 studies reported in 74 papers were eligible for inclusion. The overall meta-analysis included 5877 participants and showed reductions in pain favouring exercise (standardised mean difference − 0.45 95% confidence interval − 0.62, − 0.28). For most ( 82%) of the subgroup analyses, the direction of effect favoured exercise compared with usual care, with effect sizes ranging from small to large (median effect size − 0.35 range − 0.03 to − 1.17). The overall strength of evidence for the effect of exercise on cancer-related pain was very low. The findings provide support that exercise participation does not worsen cancer-related pain and that it may be beneficial. Better pain categorisation and inclusion of more erse cancer populations in future research would improve understanding of the extent of benefit and to whom. CRD42021266826.
Publisher: Elsevier BV
Date: 10-2019
Publisher: Elsevier BV
Date: 04-2021
Publisher: Elsevier BV
Date: 11-2018
Publisher: Elsevier BV
Date: 07-2021
DOI: 10.1093/AJCN/NQAB046
Publisher: Hindawi Limited
Date: 11-2021
DOI: 10.1002/TSM2.294
Publisher: Frontiers Media SA
Date: 22-08-2022
DOI: 10.3389/FPHYS.2022.967169
Abstract: Purpose: This study assessed the biological reliability of peripheral human cytokines and adipokines, and the influence of participant characteristics on total error. This has essential application to interventional cytokine measurement to ensure that reported results are interpreted with confidence. Methods: Participants (49% female, 18–85 years, n = 84) completed two consecutive-day testing sessions. Participants provided a venous blood s le at the same time of day across two consecutive days, under standardized participant presentation, including 24-h rested and 12-h fasted conditions. Multiplex immunoassay was used to assess inflammatory analytes from s les (predominantly plasma). Repeat measurements were conducted between-day for total precision quantification, and technical (technique) error was negated from the total to provide an estimate of biological (attributed to participant presentation) error. Results: Whilst there was no evidence of statistically significant biological error, a small amount of biological error was consistently present across most analytes (∼3.3%/0.07 pg/ml), which was largest for measurement of leptin (7.3%/210 pg/ml). There was also an influence of sex on reliability of leptin and adiponectin (total model explained 6–7% of error variation), where females demonstrated the greatest error. Conclusion: Biological error reported in this study should be applied to any future study or in idual with a repeated measurement of cytokine concentrations over time that maintain best practice procedures (12-h fasted, 24-h rested). In most cases, raw error should be used, with exceptions for women for measurement of leptin and adiponectin. This approach will ensure that results are reported with certainty for improved reporting of intervention efficacy.
Publisher: Springer Science and Business Media LLC
Date: 17-05-2023
DOI: 10.1007/S00520-023-07790-8
Abstract: To systematically synthesise evidence of exercise intervention efficacy for physical sychosocial outcomes that matter to women during/following treatment for gynaecological cancer. Five databases were searched (PubMed, EMBASE, CINAHL, PsychInfo, Scopus). Exercise-only intervention studies that included women during/ following treatment for any gynaecological cancer, with/ without control comparison, on any physical or psychosocial outcome(s), were included and qualitatively appraised using the Revised Cochrane Risk of Bias tool and a modified Newcastle-Ottawa Scale. Seven randomised controlled trials (RCTs), three single-arm pre-post studies, and one prospective cohort study satisfied were included (11 studies). Most studies were completed following treatment (91%), included combined (aerobic and resistance 36%) and aerobic (36%) training, were fully/mostly (63%) unsupervised, and had a moderate-to-high risk of bias. Overall, 33 outcomes (64% objectively-measured) were assessed. Improvements were observed in aerobic capacity (V̇O 2 Peak +1.6 mL/kg/min, 6-minute walk distance +20-27 m), lower- (30-second sit-to-stand +2-4 repetitions) and upper-limb strength (30-second arm curl +5 repetitions 1RM grip strength/chest press +2.4-3.1 kg), and agility (timed up-and-go -0.6 seconds). However, changes in quality of life, anthropometry/body composition, balance and flexibility were inconsistent. There was no evidence to support worsening of outcomes. Preliminary research into the role of exercise post-gynaecological cancer suggests an improvement in exercise capacity, muscular strength, and agility which, in the absence of exercise, typically decline following gynaecological cancer. Future exercise trials involving larger and more erse gynaecological cancer s les will improve understanding of the potential and magnitude of effect of guideline-recommended exercise on outcomes that matter to patients.
No related grants have been discovered for Grace Laura Rose.