ORCID Profile
0000-0002-0523-168X
Current Organisations
CSIRO Black Mountain Laboratories
,
CSIRO
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Elsevier BV
Date: 09-2021
Publisher: Elsevier BV
Date: 07-2021
Publisher: Springer Science and Business Media LLC
Date: 12-2021
DOI: 10.1186/S12284-021-00543-3
Abstract: Diet-related noncommunicable diseases impose a heavy burden on human health worldwide. Rice is a good target for diet-related disease prevention strategies because it is widely consumed. Liu et al . (Proc Natl Acad Sci USA 115(44):11327–11332, 2018. 0.1073 nas.1806304115 ) demonstrated that increasing the number of cell layers and thickness of putative aleurone in ta2-1 ( thick aleurone 2-1 ) mutant rice enhances simultaneously the content of multiple micronutrients. However, the increases of aleurone-associated nutrients were not proportional to the increases in the aleurone thickness. In this study, first, cytohistological analyses and transmission electron microscopy demonstrated that the multilayer in ta2-1 exhibited aleurone cell structural features. Second, we detected an increase in insoluble fibre and insoluble bound-phenolic compounds, a shift in aleurone-specific neutral non-starch polysaccharide profile, enhancement of phytate and minerals such as iron, zinc, potassium, magnesium, sulphur, and manganese, enrichment of triacylglycerol and phosphatidylcholine but slight reduction in free fatty acid, and an increase in oleic fatty acid composition. These findings support our hypothesis that the expanded aleurone-like layers in ta2-1 maintained some of the distinctive aleurone features and composition. We provide perspectives to achieve even greater filling of this expanded micronutrient sink to provide a means for multiple micronutrient enhancements in rice.
Publisher: Research Square Platform LLC
Date: 17-03-2021
DOI: 10.21203/RS.3.RS-300756/V1
Abstract: Background Diet-related non communicable diseases (NCDs) impose a heavy burden on human health worldwide. Rice is a good target for diet-related disease prevention strategies because it is widely consumed. Liu et al. demonstrated that increasing the number of cell layers and thickness of putative aleurone in ta2-1 (thick aleurone 2-1) mutant rice enhances simultaneously the content of multiple micronutrients. However, the increases of aleurone-associated nutrients were not proportional to the increases in the aleurone thickness. Results In this study, first, cytohistological analyses and transmission electron microscopy demonstrated that the multilayer in ta2-1 exhibited aleurone cell structural features. Second, we detected an increase in insoluble fibre and insoluble bound-phenolic compounds, a shift in aleurone-specific NNSP (neutral non-starch polysaccharide) profile, enhancement of phytate and minerals such as iron, zinc, potassium, magnesium, sulphur, and manganese, enrichment of triacylglycerol and phosphatidylcholine but slight reduction in free fatty acid, and an increase in oleic fatty acid composition. Conclusion These findings support our hypothesis that the expanded aleurone-like layers in ta2-1 maintained the distinctive aleurone features and composition associated with true aleurone. We provide perspectives to achieve even greater filling of this expanded micronutrient sink to alleviate the burden of NCDs.
Publisher: Frontiers Media SA
Date: 09-09-2021
Abstract: Lysine is the most limiting essential amino acid in cereals, and efforts have been made over the decades to improve the nutritional quality of these grains by limiting storage protein accumulation and increasing lysine content, while maintaining desired agronomic traits. The single lys3 mutation in barley has been shown to significantly increase lysine content but also reduces grain size. Herein, the regulatory effect of the lys3 mutation that controls storage protein accumulation as well as a plethora of critically important processes in cereal seeds was investigated in double mutant barley lines. This was enabled through the generation of three hordein double-mutants by inter-crossing three single hordein mutants, that had all been backcrossed three times to the malting barley cultivar Sloop. Proteome abundance measurements were integrated with their phenotype measurements proteins were mapped to chromosomal locations and to their corresponding functional classes. These models enabled the prediction of previously unknown points of crosstalk that connect the impact of lys3 mutations to other signalling pathways. In combination, these results provide an improved understanding of how the mutation at the lys3 locus remodels cellular functions and impact phenotype that can be used in selective breeding to generate favourable agronomic traits.
Publisher: Proceedings of the National Academy of Sciences
Date: 10-2018
Abstract: The aleurone, storing proteins, lipids, vitamins, and minerals, is the most nutritious part of cereal grains. Genetic analyses were conducted to screen for mutants with thickened aleurone, and identified thick aleurone 2-1 , which exhibits a multicell-layered aleurone and an improved nutritional profile. Map-based cloning showed that TA2 encodes a DNA demethylase. This study provides a strategy for enhancing the nutritional value of rice, and possibly of other cereals as well.
Location: Hong Kong
Location: Australia
Location: Hong Kong
No related grants have been discovered for Ronald YU.