ORCID Profile
0000-0002-8062-4491
Current Organisations
University of Georgia
,
Hong Kong University of Science and Technology
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Publisher: Informa UK Limited
Date: 15-10-2020
DOI: 10.1080/02640414.2019.1679575
Abstract: To help inform strategies aimed at increasing muscular fitness levels, we examined factors associated with childhood muscular fitness (strength and power) that preceded the recently observed secular decline. Data were available from a nationally representative s le of Australian children aged 7-15 years in 1985 (n = 8469). Muscular fitness measures included strength (right and left grip, shoulder extension and flexion, and leg strength) and power (standing long jump distance). Anthropometric (adiposity, fat-free mass), cardiorespiratory fitness (CRF), flexibility, speed capability, physical activity (in idual and parental), dietary quality and intake (fruit, vegetable, protein) and sociodemographic (area-level socioeconomic status (SES), school type) data were available. Statistical analyses included sex-stratified linear regression. Of all examined factors, measures of adiposity, fat-free mass, CRF, flexibility and speed capability were associated with muscular fitness at levels that met Cohen's threshold for important effects (r-squared = 0.02 to 0.28). These findings highlight the multifactorial relationship between muscular fitness and its determinants. Collectively, these factors were powerful in explaining muscular strength (females: r-squared = 0.32 males: r-squared = 0.41) and muscular power (females: r-squared = 0.36 males: r-squared = 0.42). These findings highlight modifiable and environmental factors that could be targeted to increase childhood muscular fitness.
Publisher: Oxford University Press (OUP)
Date: 18-01-2010
Publisher: Human Kinetics
Date: 2014
Abstract: We investigated associations of total sedentary behavior (SB) and objectively-measured and self-reported physical activity (PA) with obesity. Data from 1662 adults (26–36 years) included daily steps, self-reported PA, sitting, and waist circumference. SB and PA were dichotomized at the median, then 2 variables created (SB/self-reported PA SB/objectively-measured PA) each with 4 categories: low SB/high PA (reference group), high SB/high PA, low SB/low PA, high SB/low PA. Overall, high SB/low PA was associated with 95 –168% increased obesity odds. Associations were stronger and more consistent for steps than self-reported PA for men (OR 2.68, 95% CI 1.36–5.32 and OR 1.95, 95% CI 1.01–3.79, respectively) and women (OR 2.66, 95% CI 1.58–4.49 and OR 2.00, 95% CI 1.21–3.31, respectively). Among men, obesity was higher when daily steps were low, irrespective of sitting (low SB/low steps OR 2.07, 95% CI 1.03–4.17 high SB/low steps OR 2.68, 95% CI 1.36–5.32). High sitting and low activity increased obesity odds among adults. Irrespective of sitting, men with low step counts had increased odds of obesity. The findings highlight the importance of engaging in physical activity and limiting sitting.
Publisher: Elsevier BV
Date: 05-2008
Abstract: The behavioral pathways through which television (TV) viewing leads to increased adiposity in adults are unclear. We wanted to determine whether the association between TV viewing and abdominal obesity in young adults is mediated by food and beverage consumption during TV viewing time or by a reduction in overall leisure-time physical activity (LTPA). This study involved a cross-sectional analysis of data from 2001 Australian adults aged 26-36 y. Waist circumference (WC) was measured at study clinics, and TV viewing time, frequency of food and beverage consumption during TV viewing, LTPA, and demographic characteristics were self-reported. Women watching TV > 3 h/d had a higher prevalence of severe abdominal obesity (WC: > or = 88 cm) compared with women watching 3 h/d than in men watching < or = 1 h/d (PR: 2.16 95% CI: 1.37, 3.41). Adjustment for LTPA made little difference, but adjustment for food and beverage consumption during TV viewing attenuated the associations (PR: 1.48 95% CI: 1.01, 2.17 for women PR: 1.73 95% CI: 1.06, 2.83 for men). The association between TV viewing and WC in young adults may be partially explained by food and beverage consumption during TV viewing but was not explained by a reduction in overall LTPA. Other behaviors likely contribute to the association between TV viewing and obesity.
Publisher: Elsevier BV
Date: 11-2011
DOI: 10.1016/J.JSAMS.2011.04.006
Abstract: Accurately quantifying physical activity is important for investigating relations with potential correlates, but past studies have mostly relied on self-report measures, which may be susceptible to error and biases, limiting interpretability. This study aimed to examine correlates of pedometer-determined physical activity and compare them with correlates of self-reported physical activity. Cross-sectional data were taken from 2017 Australian adults (aged 26-36 years) who were involved in the Childhood Determinants of Adult Health follow-up study during 2004-2006. Daily steps were recorded for seven days using Yamax pedometers and physical activity (total min/week) was reported via the long International Physical Activity Questionnaire. Demographic, biological, behavioral, psychological, social and environmental factors were assessed. Lower education, blue collar occupation and higher mental health score (men) and low-moderate alcohol intake (women) were positively associated with self-report and pedometer-measured activity. Among men, body mass index (BMI) was inversely and physical health score was positively associated with pedometer-measured activity while smoking, low to moderate alcohol intake, higher general health and urban area of residence were positively associated with self-reported activity. Among women, age and general health status were positively associated and number of live births inversely associated with pedometer-measured activity, while lower education, blue collar occupation, part time employment, smoking, diet, higher physical health score and higher mental health score were positively associated and white collar occupation inversely associated with self-reported activity. Many physical activity correlates differed depending on the measure employed researchers should be mindful of these differences when selecting measures of physical activity.
Publisher: IOP Publishing
Date: 09-10-2007
Publisher: Elsevier BV
Date: 07-2021
Publisher: Elsevier BV
Date: 05-2008
DOI: 10.1016/J.ANNEPIDEM.2008.01.005
Abstract: To compare the ability of alternative measures of physical activity and fitness to quantify associations with health outcomes. Associations between a range of subjective and objective physical activity and fitness measures and cardiometabolic risk factors were examined using data from 1,631 Australians aged 26-36 years. Anthropometry, fitness, blood pressure, and fasting blood glucose, insulin, and lipids were measured at study clinics. Participants completed the International Physical Activity Questionnaire (IPAQ) and 7-day pedometer diaries they also reported sedentary behavior (sitting, television viewing). In men and women, associations were strongest for fitness, with those in the highest (vs. lowest) fitness quarter having a 75% to 80% lower prevalence of two or more primary risk factors (waist circumference, high-density lipoprotein cholesterol, and insulin resistance). In men, a 60% to 70% reduced prevalence of two or more risk factors was observed across extreme quarters of IPAQ leisure, IPAQ vigorous, sitting duration, and pedometer measures. Similar reductions in prevalence were observed only across extreme quarters of pedometer activity and television viewing in women. Associations between alternative measures and cardiometabolic risk were relatively independent, suggesting that a range of physical activity and fitness measures may be needed to most accurately quantify associations between physical activity and health.
Publisher: American Diabetes Association
Date: 23-12-2008
DOI: 10.2337/DC08-1638
Abstract: To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance. A prospective cohort study set in Australia in 2004–2006 followed up a cohort of 647 adults who had participated in the Australian Schools Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and BMI ≥30 kg/m2, respectively. Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95% CI 1.6–5.6]) and insulin resistance (1.7 [1.1–2.6]). A decline in fitness level between childhood and adulthood was associated with increased obesity (4.5 [2.6–7.7]) and insulin resistance (2.1 [1.5–2.9]) per unit decline. A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 08-07-2022
DOI: 10.1249/MSS.0000000000002990
Abstract: To promote greater muscular strength across the life course and, in turn, help improve long-term health outcomes, strategies aimed at increasing muscular strength are required. To inform these strategies, this study identified childhood factors associated with muscular strength trajectories. Prospective longitudinal study of 1280 Childhood Determinants of Adult Health participants who had a range of potentially modifiable factors (e.g., anthropometric measures, physical activity) and health and risk motivation items (e.g., attitudes, beliefs, and intentions on health-related actions) measured in childhood and had their muscular strength assessed up to three times between childhood and midlife. Associations between childhood factors and three predetermined life course muscular strength trajectories (identified previously using group-base trajectory modeling as follows: above average and increasing, average, and below average and decreasing) were examined using log multinomial regression. Greater physical fitness, physical activity, fat-free mass, enjoyment of physical activity, physical education, and school sports, and positive attitudes regarding the importance of exercising, staying fit, and body image were associated with a lower likelihood of being in the below average and decreasing muscular strength trajectory (relative risk range, 0.45–0.98). Greater physical fitness, physical activity, and fat-free mass, and attending an independent school were associated with a higher likelihood of being in the above average and increasing muscular strength trajectory (relative risk range, 1.03–1.93). In addition to providing health benefits in the short term, physical activity, physical fitness, positive health attitudes, and healthy weight in childhood may lead to better muscular strength in the long term.
Publisher: Elsevier BV
Date: 09-2018
DOI: 10.1016/J.JSAMS.2018.02.002
Abstract: To assess whether childhood cardiorespiratory fitness (CRF) and muscular fitness phenotypes (strength, power, endurance) predict adult glucose homeostasis measures. Prospective longitudinal study. Study examining participants who had physical fitness measured in childhood (aged 7-15 years) and who attended follow-up clinics approximately 20 years later and provided a fasting blood s le which was tested for glucose and insulin. Physical fitness measurements included muscular strength (right and left grip, shoulder flexion, shoulder and leg extension), power (standing long jump distance) and endurance (number of push-ups in 30s), and CRF (1.6km run duration). In adulthood, fasting glucose and insulin levels were used to derive glucose homeostasis measures of insulin resistance (HOMA2-IR) and beta cell function (HOMA2-β). A standard deviation increase in childhood CRF or muscular strength (males) was associated with fasting glucose (CRF: β=-0.06mmol/L), fasting insulin (CRF: β=-0.73mU/L strength: β=-0.40mU/L), HOMA2-IR (CRF: β=-0.06 strength: β=-0.05) and HOMA2-β (CRF: β=-3.06% strength: β=-2.62%) in adulthood, independent of the alternative fitness phenotype (all p 0.06). CRF and muscular fitness in childhood were inversely associated with measures of fasting insulin, insulin resistance and beta cell function in adulthood. Childhood CRF and muscular fitness could both be potential independent targets for strategies to help reduce the development of adverse glucose homeostasis.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-2013
Publisher: Springer Science and Business Media LLC
Date: 20-12-2011
DOI: 10.1007/S00421-011-2286-4
Abstract: Low cardiorespiratory fitness (CRF) is a risk factor for cardiovascular disease (CVD) but the association of muscular fitness phenotypes (strength, endurance and power) on CVD risk in youth has not been examined. We examined the cross-sectional association between muscular fitness phenotypes with in idual and clustered CVD risk factors and determined if any potential associations are independent of CRF. Participants were 1,642 youth aged 9, 12, and 15 years from the Australian Schools Health and Fitness Survey that had muscular strength (dynamometer), power (standing long-jump), and endurance (push-ups) as well as CRF (1.6 km run-time) measured. Outcomes included established risk factors (body mass index, waist circumference, blood lipids and blood pressure) and a clustered CVD risk-score. Muscular strength, endurance, and power were inversely associated with clustered CVD risk (all P < 0.05). After adjustment for body mass index, the association remained for muscular endurance and power (all P ≤ 0.001), but not strength. Muscular power was inversely related to prevalence of clustered CVD risk (≥80th percentile) within low (P trend < 0.001), moderate (Ptrend < 0.001), and high (Ptrend = 0.001) CRF categories. Among youth, low muscular fitness levels as well as low CRF should be avoided for primary CVD prevention.
Publisher: Human Kinetics
Date: 05-2010
DOI: 10.1123/JPAH.7.3.410
Abstract: The Global Physical Activity Questionnaire (GPAQ) was developed as an improvement of the International Physical Activity Questionnaire (IPAQ) for use in cross-cultural settings. This study compared the reliability and validity of GPAQ and IPAQ in Vietnam. 251 adults were randomly selected from a population-based survey (n = 1978) of noncommunicable disease risk factors. GPAQ and IPAQ were administered on 2 occasions. Participants wore pedometers and logged their physical activity (PA) for 7 consecutive days. Test-retest correlations of GPAQ measurements differed for participants (n = 153) with stable work patterns (work PA r = .43, total PA r = .39) and those (n = 98) with unstable work patterns (work PA r = −0.02, total PA r = −0.05). IPAQ measurements did not differ in this way. GPAQ reliability was poorer for transport (GPAQ r = .25, IPAQ r = .60) and for leisure (GPAQ r = .21, IPAQ r = .45) PA. GPAQ estimates of total PA for participants with stable work patterns were moderately correlated with IPAQ total PA ( r = .32), steps per day ( r = .39), and PA log ( r = .31). The modifications made when designing GPAQ improved its reliability for persons with stable work patterns, but at the expense of poorer reliability for persons with more variable PA. GPAQ did not have superior validity to IPAQ.
Publisher: Oxford University Press (OUP)
Date: 31-05-2011
Abstract: it is uncertain as to which measures of gait best predict those who are likely to fall. Our aim was to investigate the associations of gait and gait variability measures with incident falls risk. in iduals aged 60-86 years (n = 412) were randomly selected from the Tasmanian electoral roll. Average gait and gait variability measures were collected on a computerised walkway. Falls were recorded prospectively over 12 months. Log multinomial regression was used to estimate the relative risk of single and multiple falls associated with gait measures. Covariates included age, sex, sensorimotor and cognitive measures, mood and medications. in this population-based study greater intra-in idual variability in step length and double-support phase were linearly associated with increased risk of multiple falls (P = 0.04). Non-linear associations with multiple falls were found for gait speed P = 0.002, cadence P = 0.004 and step time variability P = 0.03. None of the gait measures predicted risk of single falls. there is an increased risk of multiple falls, but not single falls, in older people with poorer gait. Specific measures of gait and gait variability seem to confer this risk and may be amenable to interventions designed to reduce the risk of multiple falls in older people.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 30-07-2020
DOI: 10.1249/MSS.0000000000002108
Abstract: Child and adult muscular power have been shown to associate with contemporary cardiometabolic health. Muscular power typically persists (tracks) between childhood and adulthood. Few studies span childhood to adulthood, so we aimed to identify modifiable and environmental factors associated with the persistence or change in muscular power across the life course. Prospective study examining 1938 participants who had their muscular power (standing long jump distance) measured in 1985 as children 7–15 yr old and again 20 yr later in adulthood (26–36 yr old). A selection of objectively measured anthropometric characteristics (adiposity and fat-free mass), cardiorespiratory fitness (CRF), self-reported physical activity, dietary (quality and fruit, vegetable, and protein intake), and sociodemographic data were available at both time points. Muscular power was separated into thirds, and participants were reported as having persistently low, decreasing, persistently moderate, increasing, or persistently high muscular power. Higher adiposity, lower physical activity, diet quality and socioeconomic status (SES) across the life course, and lower adult CRF were associated with persistently low muscular power. Lower adult protein intake and an increase in adiposity over time were associated with decreasing muscular power. An increase in fat-free mass was associated with a reduced probability of decreasing or persistently high muscular power and an increased probability of increasing muscular power. Higher adult fruit intake was associated with increasing muscular power. Lower adiposity across the life course, higher adult CRF and SES, and higher child protein intake were associated with persistently high muscular power. Healthy weight, good CRF, greater protein intake, and high SES are important correlates of high muscular power maintained from childhood to adulthood.
Publisher: Elsevier BV
Date: 10-2012
DOI: 10.1016/J.JACC.2012.05.056
Abstract: The aim of this study was to examine the effect of resolution from metabolic syndrome (MetS) between youth and adulthood on carotid artery intima-media thickness (IMT) and type 2 diabetes mellitus (T2DM). Published findings demonstrate that youth with MetS are at increased risk of cardio-metabolic outcomes in adulthood. It is not known whether this risk is attenuated in those who resolve their MetS status. Participants (n = 1,757) from 2 prospective cohort studies were examined as youth (when 9 to 18 years of age) and re-examined 14 to 27 years later. The presence of any 3 components (low high-density lipoprotein cholesterol, high triglycerides, high glucose, high blood pressure, or high body mass index) previously shown to predict adult outcomes defined youth MetS the harmonized MetS criteria defined adulthood MetS. Participants were classified according to their MetS status at baseline and follow-up and examined for risk of high IMT and T2DM. Those with MetS in youth and adulthood were at 3.4 times the risk (95% confidence interval: 2.4 to 4.9) of high IMT and 12.2 times the risk (95% confidence interval: 6.3 to 23.9) of T2DM in adulthood compared with those that did not have MetS at either time-point, whereas those that had resolved their youth MetS status by adulthood showed similar risk to those that did not have MetS at either time-point (p > 0.20 for all comparisons). Although youth with MetS are at increased risk of adult high IMT and T2DM, these data indicate that the resolution of youth MetS by adulthood can go some way to normalize this risk to levels seen in those who have never had MetS.
Publisher: Oxford University Press (OUP)
Date: 13-10-2009
Abstract: the study of factors associated with age-related gait decline may assist in developing methods to preserve mobility in older people. to examine the associations between sensorimotor factors relevant to ageing and gait in the general older population. cross-sectional population-based study. participants aged 60-86 years (n = 278) were randomly selected using electoral roll s ling. Sensorimotor factors (quadriceps strength, reaction time, postural sway, proprioception and visual contrast sensitivity) were measured using the Physiological Profile Assessment. Gait variables (speed, cadence, step length, double support phase and step width) were recorded with a GAITRite walkway. Linear regression was used to model relationships between sensorimotor and gait variables. mean age of participants was 72.4 (7.0) years with 154 (55%) males. Better quadriceps strength, reaction time and postural sway (in men) predicted faster gait speed due to their effects on step length and/or cadence. Body weight (in men) and visual contrast sensitivity (in women) were modifying factors in these relationships. Better postural sway, reaction time (in men) and quadriceps strength (in women) predicted reduced double support phase. Modifying factors were quadriceps strength (in men) and proprioception (in women). Postural sway was the sole predictor of step width and in women only. potentially modifiable sensorimotor factors were associated with a range of gait measures, with a different pattern of in idual associations and interactions seen between the sexes. These results provide further mechanistic insights towards explaining age-related gait decline in the general older population.
Publisher: Elsevier BV
Date: 05-2022
DOI: 10.1016/J.NUMECD.2022.01.018
Abstract: Low muscular strength associates with the metabolic syndrome (MetS). However, how muscular strength measured at different life stages contribute to the development of MetS is unknown. This study compared the contribution of muscular strength measured in youth, young- and mid-adulthood with MetS in midlife. Prospective longitudinal study of 267 Childhood Determinants of Adult Health Study participants who between 1985 and 2019 had measures of muscular strength (dominant grip strength) at three life stages (youth = 9-15 years, young adulthood = 26-36 years, mid-adulthood = 36-49 years) and had their MetS status assessed in mid-adulthood. Bayesian relevant life-course exposure models quantified associations between muscular strength at each life stage with MetS and estimated the maximum accumulated effect of lifelong muscular strength. The contribution of muscular strength at each life stage with MetS was equal (youth = 38%, young adulthood = 28%, mid-adulthood = 34%). A one standard deviation increase in cumulative muscular strength was associated with 46% reduced odds of MetS. Of all MetS components, muscular strength was most strongly negatively associated with high waist circumference. A life-course approach demonstrated reduced odds of MetS in midlife was associated with cumulatively high muscular strength since youth. This supports efforts to promote physical fitness throughout life.
Publisher: American Diabetes Association
Date: 25-02-2010
DOI: 10.2337/DC09-1940
Abstract: To examine the association between depressive disorder and insulin resistance in a s le of young adults using the Composite International Diagnostic Interview to ascertain depression status. Cross-sectional data were collected from 1,732 participants aged between 26 and 36 years. Insulin resistance was derived from blood chemistry measures of fasting insulin and glucose using the homeostasis model assessment method. Those identified with mild, moderate, or severe depression were classified as having depressive disorder. The 12-month prevalence of depressive disorder was 5.4% among men and 11.7% among women. In unadjusted models mean insulin resistance was 17.2% (95% CI 0.7–36.0%, P = 0.04) higher in men and 11.4% (1.5–22.0%, P = 0.02) higher in women with depressive disorder. After adjustment for behavioral and dietary factors, the increased level of insulin resistance associated with depressive disorder was 13.2% (−3.1 to 32.3%, P = 0.12) in men and 6.1% (−4.1 to 17.4%, P = 0.25) in women. Waist circumference was identified as a mediator in the relationship between depression and insulin resistance, reducing the β coefficient in the fully adjusted models in men by 38% and in women by 42%. A positive association was found between depressive disorder and insulin resistance in this population-based s le of young adult men and women. The association seemed to be mediated partially by waist circumference.
Publisher: AMPCo
Date: 05-2007
DOI: 10.5694/J.1326-5377.2007.TB00997.X
Abstract: To examine overweight and obesity in Australian children followed through to adulthood. A cohort study of 8498 children aged 7-15 years who participated in the 1985 Australian Schools Health and Fitness Survey of these, 2208 men and 2363 women completed a follow-up questionnaire at age 24-34 years in 2001-2005. Height and weight were measured in 1985, and self-reported at follow-up. The accuracy of self-reported data was checked in 1185 participants. Overweight and obesity in childhood were defined according to international standard definitions for body mass index (BMI), and, in adulthood, as a BMI of 25-29.9 and > or =30 kg/m2, respectively, after correcting for self-report error. In those with baseline and follow-up data, the prevalence of overweight and obesity in childhood was 8.3% and 1.5% in boys and 9.7% and 1.4% in girls, respectively. At follow-up, the prevalence was 40.1% and 13.0% in men and 19.7% and 11.7% in women. The relative risk (RR) of becoming an obese adult was significantly greater for those who had been obese as children compared with those who had been a healthy weight (RR = 4.7 95% CI, 3.0-7.2 for boys and RR = 9.2 95% CI, 6.9-12.3 for girls). The proportion of adult obesity attributable to childhood obesity was 6.4% in males and 12.6% in females. Obesity in childhood was strongly predictive of obesity in early adulthood, but most obese young adults were a healthy weight as children.
Publisher: Wiley
Date: 10-2014
DOI: 10.1002/OBY.20871
Abstract: Cardiorespiratory fitness and adiposity may influence cardiovascular risk through their effects on inflammation. The long-term effects of these modifiable factors on adult inflammation remain uncertain. The associations of childhood and adulthood cardiorespiratory fitness and adiposity with adult inflammation [C-reactive protein (CRP), fibrinogen] were examined. 1,976 children examined in 1985 and re-examined as young adults in 2004-2006 were included. Cardiorespiratory fitness and adiposity were assessed at both waves. CRP and fibrinogen were measured at follow-up. Higher childhood fitness was associated with lower adult inflammation in both sexes. After adjusting for childhood adiposity, the association with CRP attenuated in males, but remained in females (average reduction of CRP 18.1% (95% CI 11.3-24.4%) per 1-SD increase in childhood fitness). Higher adult fitness, adjusting for childhood fitness (an increase in fitness from childhood to adulthood), was associated with lower adult CRP in females and lower fibrinogen in males. Higher childhood and adulthood adiposity (an increase in adiposity from childhood to adulthood) were associated with higher adult inflammation in both sexes. Prevention programs to increase fitness and reduce adiposity in childhood, and maintain a favorable fitness and weight into adulthood, may lead to reduction in adult systemic inflammation.
Publisher: Elsevier BV
Date: 10-2009
DOI: 10.1016/J.AMEPRE.2009.05.020
Abstract: Pedometers are increasingly being used to assess population levels of physical activity and as motivational tools for in iduals to increase their physical activity. To maximize their utility, a framework for classifying pedometer-determined activity into meaningful health-related categories is needed. This study investigated whether a pedometer step index proposed by Tudor-Locke and Bassett can effectively group younger and older adults according to cardiometabolic health status. Analyses (conducted in 2008) used cross-sectional data from the Childhood Determinants of Adult Health study (1793 adults aged 26-36 years collected 2004-2006) and from the Tasmanian Older Adult Cohort study (1014 adults aged 50-80 years collected 2002-2006). Participants wore a pedometer for 7 days and the prevalence of cardiometabolic health indicators, including the metabolic syndrome, elevated Pathobiological Determinants of Atherosclerosis in Youth risk scores, and elevated Framingham risk scores, was examined across the following step categories: sedentary ( or = 12,500). With the exception of younger men, in iduals achieving > or = 5000 steps had a substantially lower prevalence of adverse cardiometabolic health indicators than those obtaining fewer steps. Differences in the prevalence of adverse indicators were generally modest across higher steps-per-day categories. However, younger men and women in the high-active category had a substantially lower prevalence of some adverse health indicators. In general, the proposed index for classifying pedometer activity effectively distinguishes cardiometabolic health risk. Pedometers may be a useful tool for objectively identifying inactive in iduals at greatest risk for poor cardiometabolic health.
Publisher: Springer Science and Business Media LLC
Date: 28-09-2010
DOI: 10.1038/IJO.2010.205
Abstract: To estimate associations between alternative measures of childhood adiposity and indicators of cardio-metabolic health in adulthood, both unadjusted and adjusted for changes in adiposity from childhood to adulthood. The study consisted of a 20-year follow-up of 2188 adults who had participated in the 1985 Australian Schools Health and Fitness Survey when they were between 7 and 15 years of age. Baseline and follow-up measures of body composition included height and weight, waist and hip circumferences and skinfold thicknesses at four sites. At follow-up, participants attended study clinics where component indicators of the metabolic syndrome (MetS) (waist circumference, blood pressure, fasting blood glucose and lipids) were measured. Waist circumference and skinfold measures were the strongest predictors of subsequent MetS (2009 Joint Scientific Statement definition) in early adulthood. For ex le, relative risks (RRs) for children in the highest (vs lowest) quarter of waist circumference were 4.8 (95% confidence interval (CI): 2.5-9.2) for males and 5.8 (95% CI: 2.4-14.2) for females. After adjusting for change in waist circumference from childhood to adulthood, each 10 cm increase in childhood waist circumference was associated with an approximate twofold increase in risk for adult MetS (RR = 2.1 (95% CI: 1.7-2.7) among males and RR = 2.3 (95% CI: 1.6-3.4) among females). Elevated waist circumference and skinfold thickness measures in childhood appear to be the strongest predictors of subsequent MetS in early adulthood. The increased risk associated with higher waist circumference in childhood appears to be independent of changes in waist circumference from childhood to adulthood.
Publisher: Springer Science and Business Media LLC
Date: 22-04-2016
DOI: 10.1038/IJO.2016.61
Abstract: The objective of this study was to examine whether childhood cardiorespiratory fitness attenuates or modifies the long-term cardiometabolic risks associated with childhood obesity. The study consisted of a 20-year follow-up of 1792 adults who participated in the 1985 Australian Schools Health and Fitness Survey when they were 7-15 years of age. Baseline measures included a 1.6-km run to assess cardiorespiratory fitness and waist circumference to assess abdominal adiposity. At follow-up, participants attended study clinics where indicators of Metabolic Syndrome (MetS) (waist circumference, blood pressure, fasting blood glucose and lipids) were measured and cardiorespiratory fitness was reassessed using a submaximal graded exercise test. Both high waist circumference and low cardiorespiratory fitness in childhood were significant independent predictors of MetS in early adulthood. The mutually adjusted relative risk of adult MetS was 3.00 (95% confidence interval: 1.85-4.89) for children in the highest (vs lowest) third of waist circumference and 0.64 (95% confidence interval: 0.43-0.96) for children with high (vs low) cardiorespiratory fitness. No significant interaction between waist circumference and fitness was observed, with higher levels of childhood fitness associated with lower risks of adult MetS among those with either low or high childhood waist circumference values. Participants who had both high waist circumference and low cardiorespiratory fitness in childhood were 8.5 times more likely to have MetS in adulthood than those who had low waist circumference and high cardiorespiratory fitness in childhood. Regardless of childhood obesity status, participants with low childhood fitness who increased their relative fitness by adulthood had a substantially lower prevalence of MetS than those who remained low fit. Childhood waist circumference and cardiorespiratory fitness are both strongly associated with cardiometabolic health in later life. Higher levels of cardiorespiratory fitness substantially reduce the risk of adult MetS, even among those with abdominal obesity in childhood.
Publisher: Springer Science and Business Media LLC
Date: 14-03-2014
DOI: 10.1007/S00127-014-0863-7
Abstract: Little is known about how physical activity patterns during childhood and adolescence are associated with risk of subsequent depression. We examined prospective and retrospective associations between leisure physical activity patterns from childhood to adulthood and risk of clinical depression in young adulthood. Participants (759 males, 871 females) in a national survey, aged 9-15 years, were re-interviewed approximately 20 years later. Leisure physical activity was self-reported at baseline (1985) and follow-up (2004-2006). To bridge the interval between the two time-points, historical leisure activity from age 15 years to adulthood was self-reported retrospectively at follow-up. Physical activity was categorized into groups that, from a public health perspective, compared patterns that were least beneficial (persistently inactive) with those increasingly beneficial (decreasing, increasing and persistently active). Depression (major depressive or dysthymic disorder) was assessed using the Composite International Diagnostic Interview. Compared with those persistently inactive, males who were increasingly and persistently active had a 69 and 65 % reduced risk of depression in adulthood, respectively (all p < 0.05). In retrospective analyses, females who were persistently active had a 51 % reduced risk of depression in adulthood (p = 0.01). Similar but non-significant trends were observed for leisure physical activity in females and historical leisure activity in males. Results excluded those with childhood onset of depression and were adjusted for various sociodemographic and health covariates. Findings from both prospective and retrospective analyses indicate a beneficial effect of habitual discretionary physical activity since childhood on risk of depression in young adulthood.
Publisher: American Institute of Mathematical Sciences (AIMS)
Date: 2016
Publisher: SAGE Publications
Date: 05-09-2011
Abstract: Aims: The aim of this study was to provide descriptive population-based pedometer data from adults aged 30-45 years in Finland, and to compare daily step counts with evidence-based indices. Methods: The data was collected from 1853 participants in 7 consecutive days in winter 2007—08 in part of 27-year follow up of the Cardiovascular Risk in Young Finns study. Results: The participants took (mean±standard deviation) 7499 ± 2908 steps/day. Step counts included 1925 ± 2052 aerobic steps/day gathered in bouts of at least 10 min continuous ambulatory activity. Women had more total steps than men ((7824 ± 2925 vs. 7089 ± 2774 p 0.001). Although participants had higher mean total steps on weekdays than on weekend days, they took more aerobic steps on weekend days than weekdays (p 0.001). High-level non-manual work, and unemployment were associated with having fewer total steps, but high-level non-manual workers had more aerobic steps than other occupation groups. According to pedometer thresholds proposed by Tudor-Locke and Basset, 26% of men and 16% of women could be classified as inactive ( steps/day) and 20% of women and 15% of men would be classified as active ( ,000 steps/day). Conclusions: We conclude that about one-quarter of men and one-fifth of women are considered as inactive, based on the number of daily total steps. Our results suggest that total steps may provide a very different picture of activity from aerobic steps important differences are evident by socioeconomic position and day of the week.
Publisher: Wiley
Date: 14-08-2019
DOI: 10.1111/SMS.13529
Abstract: This study aimed to assess whether the longitudinal association between childhood muscular fitness and adult measures of glucose homeostasis persist despite changes in muscular fitness across the life course. This prospective longitudinal study included 586 participants who had their muscular power (standing long jump distance), cardiorespiratory fitness (CRF), and waist circumference measured as children (aged 9, 12, 15 years) and again 20 years later as adults. In adulthood, these participants also provided a fasting blood s le which was tested for glucose and insulin. Glucose homeostasis measures including insulin resistance (HOMA2-IR) and beta cell function (HOMA2-β) were estimated. Child and adult muscular power levels were separated into thirds, and tracking groups (persistently low, decreasing, persistently moderate, increasing, and persistently high) were created. Sex-stratified multivariable linear regression models were used to examine the association between muscular power tracking groups and adult measures of glucose homeostasis. Compared with males with persistently high muscular power, males with increasing and persistently low muscular power had higher fasting insulin (increasing: β = 1.12 mU/L, P = .04 persistently low: β = 2.12 mU/L, P = .001) and HOMA2-β (increasing: β = 8.50%, P = .03 persistently low: β = 11.27%, P = .01) independent of CRF and males with persistently low muscular power had greater fasting insulin (β = 1.22 mU/L, P = .02) and HOMA2-IR (β = 0.14, P = .02) independent of waist circumference. Non-significant associations were present for females. For males, maintaining persistently high muscular power between childhood and adulthood could lead to a healthier adult glucose homeostasis profile.
Publisher: Oxford University Press (OUP)
Date: 25-11-2009
Abstract: Intra-in idual gait variability predicts falls and disability in older people. Knowledge of factors that contribute to gait variability may lead to interventions aimed at reducing decline in mobility and falls risk. The aim of this population-based study was to examine whether poorer performance on a range of sensorimotor measures was associated with greater gait variability. In iduals aged 60-86 years (n = 412) were randomly selected from the Southern Tasmanian electoral roll. Spatial (step length and step width) and temporal (step time and double support time [DST]) gait measures were recorded with a GAITRite walkway. Variability for each gait measure was the standard deviation of measurements recorded during six walks. Sensorimotor measures included visual contrast sensitivity, lower limb proprioception, quadriceps strength, reaction time, and body sway (eyes open and closed). Regression analysis was used to determine the relationships between sensorimotor measures and gait variability. Greater sway on a foam mat (eyes closed) was associated with greater variability in all gait measures (p < .05). Slower reaction time was associated with greater variability in both temporal gait measures (p < .05), whereas poorer proprioception was only associated with greater DST variability (p = .01) and weaker quadriceps strength with greater step time variability. Other sensorimotor factors were not independently associated with gait variability. Body sway, reaction time, quadriceps strength, and proprioception are likely factors that may explain gait variability in the general older population. Further research is warranted to determine causality of these associations and whether intervention programs addressing these factors may reduce gait variability in older people.
Publisher: Oxford University Press (OUP)
Date: 02-2008
Abstract: Adequate mobility is essential to maintain an independent and active lifestyle. The aim of this cross-sectional study is to examine the associations of age with temporal and spatial gait variables in a population-based s le of older people, and whether these associations are modified by sex. Men and women aged 60-86 years were randomly selected from the Southern Tasmanian electoral roll (n = 223). Gait speed, step length, cadence, step width, and double-support phase were recorded with a GAITRite walkway. Regression analysis was used to model the relationship between age, sex, and gait variables. For men, after adjusting for height and weight, age was linearly associated with all gait variables (p <.05) except cadence (p =.11). For women, all variables demonstrated a curvilinear association, with age-related change in these variables commencing during the 7th decade. Significant interactions were found between age and sex for speed (p =.04), cadence (p =.01), and double-support phase (p =.03). Associations were observed between age and a broad range of temporal and spatial gait variables in this study. These associations differed by sex, suggesting that the aging process may affect gait in men and women differently. These results provide a basis for further research into sex differences and mechanisms underlying gait changes with advancing age.
Publisher: Springer Science and Business Media LLC
Date: 19-08-2021
DOI: 10.1007/S40279-020-01328-2
Abstract: Although low child and adult grip strength is associated with adverse cardiometabolic health, how grip strength across the life course associates with type 2 diabetes is unknown. This study identified the relative contribution of grip strength measured at specific life stages (childhood, young adulthood, mid-adulthood) with prediabetes or type 2 diabetes in mid-adulthood. Between 1985 and 2019, 263 participants had their grip strength measured using an isometric dynamometer in childhood (9–15 years), young adulthood (28–36 years) and mid-adulthood (38–49 years). In mid-adulthood, a fasting blood s le was collected and tested for glucose and glycated haemoglobin (HbA1c). Participants were categorized as having prediabetes or type 2 diabetes if fasting glucose levels were ≥ 5.6 mmol or if HbA1c levels were ≥ 5.7% (≥ 39 mmol/mol). A Bayesian relevant life course exposure model examined the association between lifelong grip strength and prediabetes or type 2 diabetes. Grip strength at each time point was equally associated with prediabetes or type 2 diabetes in mid-adulthood (childhood: 37%, young adulthood: 36%, mid-adulthood: 28%). A one standard deviation increase in cumulative grip strength was associated with 34% reduced odds of prediabetes or type 2 diabetes in mid-adulthood (OR 0.66, 95% credible interval 0.40, 0.98). Greater grip strength across the life course could protect against the development of prediabetes and type 2 diabetes. Strategies aimed at increasing muscular strength in childhood and maintaining behaviours to improve strength into adulthood could improve future cardiometabolic health.
Publisher: Wiley
Date: 05-2009
DOI: 10.1038/OBY.2008.641
Abstract: This cross-sectional study aimed to examine the association between different body composition measures, menstrual cycle characteristics, and hormonal factors in a population-based s le of young women. The study s le included 726 Australian women aged 26-36 years who were not currently taking hormonal contraceptives and were not currently pregnant or breast feeding. Anthropometric measures included BMI, waist circumference (WC), and waist-hip ratio (WHR). Menstrual cycle characteristics were self-reported and usual cycles defined as short ( or=35 days). Cycles were defined as irregular if there were >or=15 days between the longest and shortest cycle in the past 12 months. Fasting serum levels of sex hormone-binding globulin (SHBG), testosterone, insulin, and glucose were measured and the free androgen index (FAI) derived. Compared with those of normal weight, obese women had at least a twofold greater odds of having an irregular cycle, whether defined by BMI (odds ratio (OR) = 2.61 95% CI = 1.28-5.35), WC (OR 2.28 95% CI = 1.16-4.49), or WHR (OR = 2.27 95% CI = 1.09-4.72). Body composition measures were significantly positively associated with fasting insulin, testosterone, and FAI, and negatively associated with SHBG (P < 0.01). Fasting insulin, SHBG, and FAI had the strongest influence on the associations between obesity and irregular cycles, with statistically significant ORs of having an irregular cycle being attenuated to near null values following adjustment. In conclusion, both overall and central obesity were significantly associated with having an irregular menstrual cycle. This association was substantially influenced by hormonal factors, particularly insulin and SHBG.
Publisher: Springer Science and Business Media LLC
Date: 2011
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 09-2016
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 19-10-2010
DOI: 10.1161/CIRCULATIONAHA.110.940809
Abstract: The clinical utility of identifying pediatric metabolic syndrome (MetS) is controversial. This study sought to determine the status of pediatric MetS as a risk factor for adult subclinical atherosclerosis (carotid intima-media thickness [cIMT]) and type 2 diabetes mellitus (T2DM) and compare and contrast this prediction with its in idual components. Using data from the population-based, prospective, observational Bogalusa Heart and Cardiovascular Risk in Young Finns studies, we examined the utility of 4 categorical definitions of youth MetS and their components in predicting adult high cIMT and T2DM among 1781 participants aged 9 to 18 years at baseline (1984 to 1988) who were then examined 14 to 27 years later (2001–2007) when aged 24 to 41 years. Youth with MetS were at 2 to 3 times the risk of having high cIMT and T2DM as adults compared with those free of MetS at youth. Risk estimates with the use of high body mass index were similar to those of MetS phenotypes in predicting adult outcomes. Comparisons of area under the receiver operating characteristic curve and net reclassification index suggested that prediction of adult MetS, high cIMT, and T2DM in adulthood with the use of youth MetS was either equivalent or inferior to classification based on high body mass index or overweight and obesity. Youth with MetS are at increased risk of meaningful adult outcomes however, the simplicity of screening for high BMI or overweight and obesity in the pediatric setting offers a simpler, equally accurate alternative to identifying youth at risk of developing adult MetS, high cIMT, or T2DM.
Publisher: Springer Science and Business Media LLC
Date: 26-06-2018
Publisher: Springer Science and Business Media LLC
Date: 17-08-2018
DOI: 10.1038/S41366-018-0177-Z
Abstract: Childhood body mass index (BMI) predicts adult glucose homeostasis measures and type 2 diabetes mellitus, but little is known about the predictive utility of other anthropometric measures in childhood. We aimed to identify the anthropometric measure in childhood that best predicts adult glucose homeostasis measures and examine if the combination of additional anthropometric measures further improves predictive utility. A 20-year follow-up of children participating in the Childhood Determinants of Adult Health Study (n = 2345, aged 7-15 years at baseline). Baseline anthropometric measures were waist circumference (WC), WC adjusted for height, weight adjusted for height, hip circumference, waist-hip-ratio, waist-height-ratio, BMI, conicity index, abdominal volume index (AVI), body adiposity index, and a body shape index. Fasting glucose and insulin levels measured at follow-up were used to define insulin resistance (HOMA2-IR), low beta-cell function (HOMA2-β), high fasting insulin, and impaired fasting glucose (IFG). All child anthropometric measures were significantly associated with HOMA2-IR, HOMA2-β, and high fasting insulin (relative risk = 1.12-1.55), but not IFG. AVI had the largest area under receiver-operating curve (AUC) in predicting adult HOMA2-IR (AUC, 95% confidence interval: 0.610, 0.584-0.637), HOMA2-β (0.615, 0.588-0.642) and high fasting insulin (0.613, 0.587-0.639). Combining each additional anthropometric measure with AVI did not appreciably increase predictive utility (an increase of 0.001-0.002 in AUC, p > 0.05 for all). Anthropometric measures from a single time-point in childhood are associated with insulin-related outcomes 20-year later in adulthood. However, overall predictive utility was low and was not substantially enhanced by combining multiple different child anthropometric measures.
Publisher: Elsevier BV
Date: 10-2023
Publisher: Elsevier BV
Date: 02-2009
DOI: 10.1016/J.AMEPRE.2008.09.036
Abstract: Epidemiologic research suggests that physical activity is associated with decreased prevalence of depression. However, the relationship between physical activity accumulated in various domains and depression remains unclear. Further, previous population-based studies have predominantly utilized self-reported measures of physical activity and depression symptom subscales. Associations between physical activity in various domains (leisure, work, active commuting, yard/household) and depression were examined using both subjective and objective measures of physical activity and a diagnostic measure of depression. Analyses (conducted in 2007) included data from 1995 young adults participating in a national study (2004-2006). Physical activity was measured by self-report (International Physical Activity Questionnaire) and objectively as pedometer steps/day. Depression (DSM-IV 12-month diagnosis of major depression or dysthymic disorder) was assessed using the Composite International Diagnostic Interview. For women, moderate levels of ambulatory activity (>or=7500 steps/day) were associated with approximately 50% lower prevalence of depression compared with being sedentary ( or=1.25 hours/week) were associated with approximately 45% lower prevalence compared with the sedentary group (0 hours/week) (p trend=0.003). In contrast, high durations of work physical activity (>or=10 hours/week) were associated with an approximate twofold higher prevalence of depression compared with being sedentary (0 hours/week) (p trend=0.005). No significant associations were observed for steps/day in men or for other types of self-reported activity including total physical activity in both men and women. These findings indicate that the context in which physical activity is assessed and the measurement methods utilized are important considerations when investigating associations between physical activity and depression.
Publisher: Elsevier BV
Date: 10-2017
DOI: 10.1016/J.JSAMS.2017.03.021
Abstract: Low muscular fitness levels have previously been reported as an independent risk factor for chronic disease outcomes. Muscular fitness tracking, the ability to maintain levels measured at one point in time to another point in time, was assessed from youth to adulthood to provide insight into whether early identification of low muscular fitness in youth is possible. Prospective longitudinal study. Study including 623 participants who had muscular fitness measures in 1985 (aged 9, 12 or 15 years) and again 20 years later in young adulthood. Measures of muscular fitness were strength (right and left grip, leg, shoulder extension and flexion measured by dynamometer, and a combined strength score) and power (standing long jump distance). Strength and power were relatively stable between youth and adulthood the strongest tracking correlations were observed for the combined strength score (r=0.47, p≤0.001), right grip strength (r=0.43, p≤0.001) and standing long jump (r=0.43, p≤0.001). Youth in the lowest third of muscular fitness had an increased risk of remaining in the lowest third of muscular fitness in adulthood (strength: relative risk (RR)=4.70, 95% confidence interval (CI) (3.19, 6.92) power: RR=4.06 (2.79, 5.90)). Youth with low muscular fitness are at increased risk of maintaining a low muscular fitness level into adulthood. These findings warrant investigation into the long term effects of early interventions that focus on improving low muscular fitness levels in youth which could potentially improve adult muscular fitness and reduce future chronic disease outcomes.
Location: United States of America
No related grants have been discovered for Michael D Schmidt.