ORCID Profile
0000-0001-9189-7244
Current Organisation
University of Oxford
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Publisher: Public Library of Science (PLoS)
Date: 27-06-2019
Publisher: Informa UK Limited
Date: 04-2019
Publisher: Springer Science and Business Media LLC
Date: 1991
DOI: 10.1007/BF02310916
Publisher: Centers for Disease Control and Prevention (CDC)
Date: 02-2015
Publisher: Proceedings of the National Academy of Sciences
Date: 22-06-2015
Abstract: Klebsiella pneumoniae is rapidly becoming untreatable using last-line antibiotics. It is especially problematic in hospitals, where it causes a range of acute infections. To approach controlling such a bacterium, we first must define what it is and how it varies genetically. Here we have determined the DNA sequence of K . pneumoniae isolates from around the world and present a detailed analysis of these data. We show that there is a wide spectrum of ersity, including variation within shared sequences and gain and loss of whole genes. Using this detailed blueprint, we show that there is an unrecognized association between the possession of specific gene profiles associated with virulence and antibiotic resistance and the differing disease outcomes seen for K . pneumoniae .
Publisher: American Society of Tropical Medicine and Hygiene
Date: 06-03-2013
Publisher: Centers for Disease Control and Prevention (CDC)
Date: 12-2012
Publisher: Elsevier BV
Date: 02-2015
Publisher: Public Library of Science (PLoS)
Date: 21-03-2013
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for David Dance.