John Kavanagh

Characterisation of dissolved organic matter in fermentation industry effluents and comparison with model compounds

Publisher: Elsevier BV

Date: 11-2019

DOI: 10.1016/J.CHEMOSPHERE.2019.05.272

Abstract: Advanced organic characterisation methods were used to investigate the suitability of lab-based model compounds as surrogates to mimic the dissolved organic matter (DOM) of both first and second generation fermentation industry effluents. Comparisons to both humic acid and synthetic melanoidin revealed the limitations of using these model organic compounds in treatment studies of biorefinery effluent. Rapid resin fractionation (RRF) of effluent from yeast cultivated on molasses suggests that 64% of the dissolved organic matter is present in the form of very hydrophobic acid (VHPhoA) compounds. Molecular weight distribution by size exclusion chromatography (LC-OCND) and fluorophore specific intensity by fluorescence excitation and emission matrix (FEEM) of the yeast effluent was comparable to signatures from humic acid. This indicates that humic acid would be a suitable model compound for oxidation, adsorption and filtration studies. Differences among the fermentation industry effluents were found to be inherently dependent on both the biochemistry of yeast and processes used. RRF and FEEM spectra of effluent from bioethanol production on cellulosic feed highlighted a preponderance of neutral compounds with fluorophore specific intensity characteristic of non-humic compounds with a higher fraction of neutral compounds (41%) relative to VHPhoA (38%), SHPhoA (16%) and HPhi (5%) moieties. Findings were not consistent with commercial humics, synthetic melanoidins or other cellulosic and lignocellulosic based effluents from Kraft and Thermomechanical pulp mills since the actual pollutants are heavily dependent on the pre-treatment process. This suggests further work is required to develop a model compound for treatment studies of effluent from second generation bio-refineries.

Biopolymer‐Based Multilayer Microparticles for Probiotic Delivery to Colon

Publisher: Wiley

Date: 03-03-2022

DOI: 10.1002/ADHM.202102487

Abstract: The potential health benefits of probiotics may not be realized because of the substantial reduction in their viability during food storage and gastrointestinal transit. Microencapsulation has been successfully utilized to improve the resistance of probiotics to critical conditions. Owing to the unique properties of biopolymers, they have been prevalently used for microencapsulation of probiotics. However, majority of microencapsulated products only contain a single layer of protection around probiotics, which is likely to be inferior to more sophisticated approaches. This review discusses emerging methods for the multilayer encapsulation of probiotic using biopolymers. Correlations are drawn between fabrication techniques and the resultant microparticle properties. Subsequently, multilayer microparticles are categorized based on their layer designs. Recent reports of specific biopolymeric formulations are examined regarding their physical and biological properties. In particular, animal models of gastrointestinal transit and disease are highlighted, with respect to trials of multilayer microencapsulated probiotics. To conclude, novel materials and approaches for fabrication of multilayer structures are highlighted.

Towards in situ product recovery for bubble column bioreactors

Publisher: Elsevier BV

Date: 08-2020

DOI: 10.1016/J.CEJ.2020.124745

Assessment of the impact of bubble size modelling in CFD simulations of alternative bubble column configurations operating in the heterogeneous regime

Publisher: Elsevier BV

Date: 08-2018

DOI: 10.1016/J.CES.2018.04.025

Pilot-scale production of phylloquinone (vitamin K1) using a bubble column photo-bioreactor

Publisher: Elsevier BV

Date: 10-2019

DOI: 10.1016/J.BEJ.2019.107243

University Of Sydney

Location: Australia

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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE230100167

Start Date: 08-2023

End Date: 12-2024

Amount: $393,481.00

Funder: Australian Research Council

Special Research Initiatives - Grant ID: SR180200046

Start Date: 04-2020

End Date: 06-2024

Amount: $758,233.00

Funder: Australian Research Council

Linkage Projects - Grant ID: LP100100310

Start Date: 05-2010

End Date: 12-2014

Amount: $253,000.00

Funder: Australian Research Council

Linkage Projects - Grant ID: LP100100347

Start Date: 05-2010

End Date: 12-2013

Amount: $230,000.00

Funder: Australian Research Council

Linkage Projects - Grant ID: LP120100608

Start Date: 03-2012

End Date: 03-2015

Amount: $210,000.00

Funder: Australian Research Council

Linkage Projects - Grant ID: LP190100143

Start Date: 08-2020

End Date: 12-2023

Amount: $439,588.00

Funder: Australian Research Council

Industrial Transformation Training Centres - Grant ID: IC140100026

Start Date: 09-2014

End Date: 09-2018

Amount: $2,997,000.00

Funder: Australian Research Council