ORCID Profile
0000-0002-9546-7433
Current Organisations
Griffith University
,
Griffith University - Gold Coast Campus
,
Southern Cross University
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In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Physical Geography | Sociology | Educational Technology and Computing | Geomorphology | Geology | Sedimentology | Sociology of Education |
Other | Equity and Access to Education | Expanding Knowledge in Education | School/Institution Community and Environment | Environmental policy, legislation and standards not elsewhere classified
Publisher: Elsevier BV
Date: 10-2023
Publisher: Wiley
Date: 24-05-2004
DOI: 10.1002/BIES.20050
Abstract: Two prevailing paradigms explain the ersity of sex-determining modes in reptiles. Many researchers, particularly those who study reptiles, consider genetic and environmental sex-determining mechanisms to be fundamentally different, and that one can be demonstrated experimentally to the exclusion of the other. Other researchers, principally those who take a broader taxonomic perspective, argue that no clear boundaries exist between them. Indeed, we argue that genetic and environmental sex determination in reptiles should be seen as a continuum of states represented by species whose sex is determined primarily by genotype, species where genetic and environmental mechanisms coexist and interact in lesser or greater measure to bring about sex phenotypes, and species where sex is determined primarily by environment. To do otherwise limits the scope of investigations into the transition between the two and reduces opportunities to use studies of reptiles to advance understanding of vertebrate sex determination generally.
Publisher: Informa UK Limited
Date: 07-2009
Publisher: Informa UK Limited
Date: 02-01-2022
Publisher: SAGE Publications
Date: 29-10-2018
Abstract: Young children are surrounded by ubiquitous environmental print (e.g. signs, product labels) on a daily basis in their homes and communities. Parent–child interactions with environmental print has the potential to foster emergent literacy. A randomised controlled pre–posttest study was conducted to examine the effects of a parent–child environmental print programme on emergent literacy skills (letter knowledge, letter and name writing, print concepts, environmental print reading, numeral name knowledge). Parent–child dyads ( N = 32, M child age = 3.63 years) participated in an 8-week (30 minutes per week) programme that used multisensory strategies to identify, trace and write letters and words embedded in environmental print. At post-test, the environmental print group showed improvements across all measures, making significant gains in letter knowledge and environmental print reading. These findings highlight potential benefits of coaching parents to use environmental print to support aspects of young children’s growth of emergent literacy skills.
Publisher: Springer Science and Business Media LLC
Date: 18-11-2009
Publisher: Informa UK Limited
Date: 23-07-2019
Publisher: Elsevier BV
Date: 2023
Publisher: Informa UK Limited
Date: 20-09-2012
Publisher: Informa UK Limited
Date: 11-2020
Publisher: Informa UK Limited
Date: 10-01-2012
Publisher: Springer Science and Business Media LLC
Date: 15-11-2015
Publisher: Springer Science and Business Media LLC
Date: 10-08-2023
DOI: 10.1186/S13046-023-02785-Z
Abstract: TP53 , encoding the tumor suppressor p53, is frequently mutated in various cancers, producing mutant p53 proteins (mutp53) which can exhibit neomorphic, gain-of-function properties. The latter transform p53 into an oncoprotein that promotes metastatic tumor progression via downstream effectors such as ENTPD5, an endoplasmic reticulum UDPase involved in the calnexin/calreticulin cycle of N-glycoprotein biosynthesis. Elucidating the mechanisms underlying the pro-metastatic functions of the mutp53-ENTPD5 axis is crucial for developing targeted therapies for aggressive metastatic cancer. We analyzed pancreatic, lung, and breast adenocarcinoma cells with p53 missense mutations to study the impact of mutp53 and ENTPD5 on the N-glycoproteins integrin-α5 (ITGA5) and integrin-β1 (ITGB1), which heterodimerize to form the key fibronectin receptor. We assessed the role of the mutp53-ENTPD5 axis in integrin-dependent tumor-stroma interactions and tumor cell motility using adhesion, migration, and invasion assays, identifying and validating therapeutic intervention targets. We employed an orthotopic xenograft model of pancreatic ductal adenocarcinoma to examine in viv o targeting of mutp53-ENTPD5-mediated ITGA5 regulation for cancer therapy. Mutp53 depletion diminished ITGA5 and ITGB1 expression and impaired tumor cell adhesion, migration, and invasion, rescued by ENTPD5. The mutp53-ENTPD5 axis maintained ITGA5 expression and function via the calnexin/calreticulin cycle. Targeting this axis using ITGA5-blocking antibodies, α-glucosidase inhibitors, or pharmacological degradation of mutp53 by HSP90 inhibitors, such as Ganetespib, effectively inhibited ITGA5-mediated cancer cell motility in vitro. In the orthotopic xenograft model, Ganetespib reduced ITGA5 expression and metastasis in an ENTPD5-dependent manner. The mutp53-ENTPD5 axis fosters ITGA5 and ITGB1 expression and tumor cell motility through the calnexin/calreticulin cycle, contributing to cancer metastasis. ITGA5-blocking antibodies or α-glucosidase inhibitors target this axis and represent potential therapeutic options worth exploring in preclinical models. The pharmacologic degradation of mutp53 by HSP90 inhibitors effectively blocks ENTPD5-ITGA5-mediated cancer cell motility and metastasis in vivo, warranting further clinical evaluation in p53-mutant cancers. This research underscores the significance of understanding the complex interplay between mutp53, ENTPD5, and the calnexin/calreticulin cycle in integrin-mediated metastatic tumor progression, offering valuable insights for the development of potential therapeutic strategies.
Publisher: Informa UK Limited
Date: 21-11-2017
Publisher: Frontiers Media SA
Date: 18-10-2019
Publisher: Cambridge University Press (CUP)
Date: 12-05-2022
DOI: 10.1017/JGC.2021.5
Abstract: Resilience can be a protective trait to promote mental health when implemented in the early years. This study explored the use of storytelling to foster children’s learning of resilience. A pedagogically appropriate storybook was used to facilitate and embed the skills of resilience in children at primary school. Teachers ( n = 2) and community-based sports officers ( n = 2) read the storybook to children enrolled in Kindergarten (first formal year of schooling) ( n = 20), Year 1 ( n = 20) and Year 2 ( n = 20). The total number in the participant group was 60, aged 4–8 years old. Following the initial reading, teachers continued to deliver the storybook to children over a 4-week intervention period. All participants were interviewed about their perceptions of the storybook, and their responses were coded into key themes mapped by the Grotberg Resilience Framework. Results indicated that storytelling as a tool provided children with positive resilience-based behavioural intervention opportunities.
Publisher: Informa UK Limited
Date: 24-11-2021
Publisher: Informa UK Limited
Date: 12-2013
Publisher: Springer Science and Business Media LLC
Date: 05-0012
DOI: 10.1007/S10577-005-1010-9
Abstract: The bearded dragon, Pogona vitticeps (Agamidae: Reptilia) is an agamid lizard endemic to Australia. Like crocodilians and many turtles, temperature-dependent sex determination (TSD) is common in agamid lizards, although many species have genotypic sex determination (GSD). P. vitticeps is reported to have GSD, but no detectable sex chromosomes. Here we used molecular cytogenetic and differential banding techniques to reveal sex chromosomes in this species. Comparative genomic hybridization (CGH), GTG- and C-banding identified a highly heterochromatic microchromosome specific to females, demonstrating female heterogamety (ZZ/ZW) in this species. We isolated the P. vitticeps W chromosome by microdissection, re- lified the DNA and used it to paint the W. No unpaired bivalents were detected in male synaptonemal complexes at meiotic pachytene, confirming male homogamety. We conclude that P. vitticeps has differentiated previously unidentifable W and Z micro-sex chromosomes, the first to be demonstrated in an agamid lizard. Our finding implies that heterochromatinization of the heterogametic chromosome occurred during sex chromosome differentiation in this species, as is the case in some lizards and many snakes, as well as in birds and mammals. Many GSD reptiles with cryptic sex chromosomes may also prove to have micro-sex chromosomes. Reptile microchromosomes, long dismissed as non-functional minutiae and often omitted from karyotypes, therefore deserve closer scrutiny with new and more sensitive techniques.
Publisher: Informa UK Limited
Date: 27-11-2018
Publisher: Australasian Society for Computers in Learning in Tertiary Education
Date: 24-04-2011
DOI: 10.14742/AJET.970
Abstract: span The discipline of statistics seems well suited to the integration of technology in a lecture as a means to enhance student learning and engagement. Technology can be used to simulate statistical concepts, create interactive learning exercises, and illustrate real world applications of statistics. The present study aimed to better understand the use of such applications during lectures from the student's perspective. The technology used included multimedia, computer-based simulations, animations, and statistical software. Interviews were conducted on a stratified random s le of 38 students in a first year statistics course. The results showed three global effects on student learning and engagement: showed the practical application of statistics, helped with understanding statistics, and addressed negative attitudes towards statistics. The results are examined from within a blended learning framework and the benefits and drawbacks to the integration of technology during lectures are discussed. /span
Publisher: Wiley
Date: 20-08-2019
DOI: 10.1002/TRTR.1865
Publisher: Informa UK Limited
Date: 07-02-2020
Publisher: Informa UK Limited
Date: 04-07-2022
Publisher: Cambridge University Press (CUP)
Date: 10-09-2022
DOI: 10.1017/JGC.2021.23
Abstract: The concept of resilience and mindfulness is becoming increasingly popular in schools worldwide in response to critical issues such as escalating teacher stress and burnout. This article explores the concept of mindfulness as a supportive practice to build resilience in times of stress in relation to reducing or preventing teacher burnout. It aims to provide practical strategies for psychologists and counsellors in schools to empower teachers with coping strategies when encountering stress. What current research literature reveals about the effectiveness of resilience and mindfulness for supporting the wellbeing of preservice and inservice teachers is discussed. Overall, the research shows that practising mindfulness to build resilience is beneficial because it helps teachers focus on the present and improves attention, self-awareness and emotional regulation, which can reduce stress and enhance wellbeing. However, further empirical studies are needed to provide deeper insights of these benefits for teachers. Recommendations for psychologists and counsellors in supporting teachers on practising mindfulness and resilience are provided.
Publisher: Informa UK Limited
Date: 04-03-2023
Publisher: Informa UK Limited
Date: 06-2009
Publisher: Informa UK Limited
Date: 14-11-2022
Publisher: Wiley
Date: 31-08-2023
DOI: 10.1111/JCAL.12866
Publisher: Springer Science and Business Media LLC
Date: 18-05-2016
Publisher: MDPI AG
Date: 10-10-2020
Abstract: It is well-recognised that disengagement is a growing problem in schools across the globe. Furthermore, statistics show that nearly 60% of all gifted students are not actualising their potential, exposing the loss of potential for both the in idual and society. While disengagement and underachievement are complex issues with no one root cause, it is well-established that when students are actively engaged in their learning, they learn more effectively. Talent actualisation is not guaranteed just because a student is gifted. As such there is heightened concern about student (dis)engagement, where there is a failure to adequately support (re)engagement so that gifted potential can develop into talent actualisation, which is evidenced through mastery. This conceptual article provides a new lens through which to explore (re)engagement opportunities for gifted students by conceptualising the interrelationship between three interconnected constructs: (1) four engagement dimensions (behavioural, affective, social, and cognitive) (2) Neihart and Betts’ six profiles of the gifted and (3) appropriate pedagogical approaches aimed at (re)engagement. The authors’ focus on proposing new conceptualisations of these three interdependent constructs through a framework titled the (Re) Engagement Nexus Model. This model is intended as a starting point for future research in personalising (re)engagement opportunities for gifted learners and preventing underachievement and disengagement before it becomes entrenched.
Publisher: The Company of Biologists
Date: 04-2023
DOI: 10.1242/DEV.201185
Abstract: Computational analysis of bio-images by deep learning (DL) algorithms has made exceptional progress in recent years and has become much more accessible to non-specialists with the development of ready-to-use tools. The study of oogenesis mechanisms and female reproductive success has also recently benefited from the development of efficient protocols for three-dimensional (3D) imaging of ovaries. Such datasets have a great potential for generating new quantitative data but are, however, complex to analyze due to the lack of efficient workflows for 3D image analysis. Here, we have integrated two existing open-source DL tools, Noise2Void and Cellpose, into an analysis pipeline dedicated to 3D follicular content analysis, which is available on Fiji. Our pipeline was developed on larvae and adult medaka ovaries but was also successfully applied to different types of ovaries (trout, zebrafish and mouse). Image enhancement, Cellpose segmentation and post-processing of labels enabled automatic and accurate quantification of these 3D images, which exhibited irregular fluorescent staining, low autofluorescence signal or heterogeneous follicles sizes. In the future, this pipeline will be useful for extensive cellular phenotyping in fish or mammals for developmental or toxicology studies.
Publisher: Informa UK Limited
Date: 03-2010
Publisher: SAGE Publications
Date: 10-12-2015
Abstract: Young children living in technology-based communities are using touch-screen tablets (e.g. iPads) to engage with the digital world at an early age. The intuitive touch-screen interface, easily downloadable apps (applications) and mobility of tablets drive their increasing popularity with pre-schoolers. This review examines research to date on tablets, apps and emergent literacy in young children in the home and at pre-school. Evidence is building that suggests tablets have the potential to foster emergent writing and letter knowledge. Although the impact of tablets on emergent literacy is not yet fully known, developing themes highlight potential benefits and hindrances of tablets for emergent literacy. Two important considerations are the quality of emergent literacy apps and the importance of scaffolding young children's use of tablets at home and pre-school to support emergent literacy development. Directions for future research and recommendations for parents and teachers are discussed.
Publisher: Informa UK Limited
Date: 12-09-2023
Publisher: Wiley
Date: 06-2000
DOI: 10.1046/J.1365-294X.2000.00916.X
Abstract: Many studies in molecular ecology have focused on the use of repeat DNA markers to determine the nature of mating systems in a wide variety of animal species. Whilst these studies typically have focused on important issues such as the evolutionary consequences of fitness variation among males, genetic studies of mating systems are potentially also important because they can generate information of significance to wider issues in wildlife management. For ex le, genetically modified, sexually transmitted viral diseases have been suggested as potential agents for the control of vertebrate pest species. An understanding of the epidemiology of such agents requires an intimate knowledge of the sexual contact rates between in iduals of the target species. Here, we report the use of minisatellite DNA profiling to reveal the mating system in two New Zealand populations of the introduced Australian brushtail possum. The brushtail possum is New Zealand's most important mammalian pest and a species for which control by a sexually transmitted immunocontraceptive has been proposed. Encouragingly, we report considerable variation in the reproductive success of males at both study sites, with one male siring offspring from four females in one year (mean no. of offspring/reproductively successful male/year at the two sites is 1.95-2.15), while many sired none. This bias in the pattern of reproductive success among males will probably facilitate the spread of an immunocontraceptive agent and thereby increase the power of this approach to biological control.
Publisher: Springer Science and Business Media LLC
Date: 2001
Publisher: Informa UK Limited
Date: 03-07-2020
Publisher: Informa UK Limited
Date: 04-07-2023
Publisher: Informa UK Limited
Date: 03-2010
Publisher: Springer Science and Business Media LLC
Date: 30-10-2020
Publisher: Springer Science and Business Media LLC
Date: 04-09-2014
Publisher: MDPI AG
Date: 31-01-2022
Abstract: This article draws on case study findings of educator leadership in an online gifted education school, which emerged from a larger study exploring online engagement practices used by specialist gifted education teachers to (re)engage gifted learners. The gifted education teachers and their team leader were interviewed about leadership practices for supporting online engagement of gifted primary and high school students. Semi-structured interview data were transcribed, coded, and thematically analysed. Findings related to teachers voicing the importance of a passionate and committed team leader who understood giftedness and who acted as a facilitator in both the continuous development of teaching team skills and facilitation of online engagement practices for gifted students. Findings indicated five key themes related to transformational leadership practices: (1) understanding requirements of online practices for teaching gifted students (2) supporting digital and online innovation and creativity for engaging gifted students (3) leveraging the unique skills of the specialist teaching team for teaching gifted students in the online space (4) actively facilitating and encouraging (re)engagement of gifted students through online participation (5) follow-through to meet the needs and concerns of the specialist teaching team, gifted students, and their parents and/or carers. These leadership practices are of importance for actively supporting gifted education teachers and their students in online learning environments in order to achieve positive student engagement and learning outcomes commensurate with student potential.
Publisher: Elsevier BV
Date: 2014
Publisher: Informa UK Limited
Date: 28-10-2014
Publisher: SAGE Publications
Date: 11-11-2012
Abstract: Young children are surrounded by environmental print on a daily basis. Through their visual exploration of environmental print, coupled with sociocultural experiences, children gain valuable semantic and symbolic knowledge as they make sense of their world. The aim of this review is to examine the question of whether environmental print has value as a literacy learning resource, and if so, the mechanisms by which it promotes literacy development. It is shown that interactions with environmental print in the child's sociocultural context can develop their logographic reading skills. These skills, in turn, promote the development of emergent literacy skills that are the precursors to conventional reading skills. Environmental print may also be used more directly when parents and childhood educators use it to scaffold the learning of emergent literacy skills. It is recommended that parents and early childhood educators capitalize on children's natural attraction to environmental print by using it to promote their literacy development.
Publisher: Springer Science and Business Media LLC
Date: 17-04-2020
Publisher: Bloomsbury Academic
Date: 2023
Publisher: S. Karger AG
Date: 2012
DOI: 10.1159/000337681
Abstract: The Early Nutrition Academy and the Child Health Foundation, in collaboration with the Committee on Nutrition, European Society for Paediatric Gastroenterology, Hepatology and Nutrition, held a workshop in March 2011 to explore guidance on acquiring evidence on the effects of nutritional interventions in infants and young children. The four objectives were to (1) provide guidance on the quality and quantity of evidence needed to justify conclusions on functional and clinical effects of nutrition in infants and young children aged years (2) agree on a range of outcome measures relevant to nutrition trials in this age group for which agreed criteria are needed (3) agree on an updated ‘core data set’ that should generally be recorded in nutrition trials in infants and young children, and (4) provide guidance on the use of surrogate markers in paediatric nutrition research. The participants discussed these objectives and agreed to set up six first working groups under the auspices of the Consensus Group on Outcome Measures Made in Paediatric Enteral Nutrition Clinical Trials (COMMENT). Five groups will aim to identify and define criteria for assessing key outcomes, i.e. growth, acute diarrhoea, atopic dermatitis and cows’ milk protein allergy, infections and ‘gut comfort’. The sixth group will review and update the ‘core data set’. The COMMENT Steering Committee will discuss and decide upon a method for reaching consensus which will be used by all working groups and plan to meet again within 2 years and to report and publish their conclusions.
Publisher: Informa UK Limited
Date: 11-01-2017
Publisher: Informa UK Limited
Date: 19-07-2019
Publisher: Informa UK Limited
Date: 11-09-2019
Publisher: Springer Science and Business Media LLC
Date: 17-03-2021
Publisher: SAGE Publications
Date: 27-12-2019
Abstract: This article uses a sociomaterial perspective to explore how deficit views of young children’s language and literacy are sustained and can be challenged. Foregrounding the notion of multiplicity, it considers how erse sociomaterial relations work to uphold particular kinds of practice and particular arrangements of bodies and things over others. These relations may interfere with and interface with each other in different ways, sometimes sustaining but also potentially disrupting deficit discourses and practices. Our sociomaterial perspective is illustrated with a short vignette from a study of children and touchscreen tablets in an early years setting. An initial analysis is followed by a series of alternate and tentative tracings of other kinds of relations that play through those moments. The article contributes to debates about social inequality by troubling the certainties generated though deficit models of children’s literacy, whilst working proactively to envision and produce alternate possibilities that foreground the potentialities generated as people and other materials assemble together.
Publisher: Informa UK Limited
Date: 29-08-2023
Publisher: Elsevier BV
Date: 06-2016
Publisher: Elsevier BV
Date: 2018
Publisher: Springer Science and Business Media LLC
Date: 06-06-2013
Publisher: Springer Science and Business Media LLC
Date: 2003
Publisher: Griffith University
Date: 2012
DOI: 10.25904/1912/2409
Publisher: Informa UK Limited
Date: 11-2013
Publisher: Wiley
Date: 05-12-2014
DOI: 10.1002/RRQ.66
Publisher: SAGE Publications
Date: 07-02-2014
Abstract: Young children interact with touch screen tablets at home and this may impact upon emergent literacy. The present study examined home access and use of touch screen tablets, as reported by parents, in Australian pre-schoolers ( N = 109) aged 3–5 years and whether this was associated with emergent literacy skills (letter name and sound, numeral identification, print concepts and name writing). Children with greater access to tablets were found to have higher letter sound and name writing skills. No relationships were found between time on tablets and emergent literacy skills. The quality of experiences rather than time spent on tablets may be important especially when viewed within a socio-cultural framework. Most parents (69%) reported that tablets were easy for their child to operate and believed tablets support early literacy development (70%). 53% believed children should have access to tablets at pre-school. Tablets have the potential to foster emergent literacy although this may depend upon the quality of digital interactions.
Publisher: Informa UK Limited
Date: 02-06-2016
Start Date: 07-2008
End Date: 06-2011
Amount: $288,650.00
Funder: Australian Research Council
View Funded ActivityStart Date: 04-2021
End Date: 06-2024
Amount: $251,176.00
Funder: Australian Research Council
View Funded Activity