ORCID Profile
0000-0002-4537-7624
Current Organisation
University Clinics of Dental Medicine, University of Geneva
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Publisher: Wiley
Date: 16-10-2021
DOI: 10.1111/CLR.13831
Abstract: Soft‐tissue volume augmentation treatments do not provide the satisfactory long‐term functional and esthetic outcomes. The aim of the study was to develop a standardized digital procedure to design in idual soft‐tissue substitutes (STS) and apply mathematical modeling to obtain average shape STS for single posterior tooth defects. Thirty‐three casts from 30 patients were scanned. STS were designed with a computer‐aided design software and a systematic procedure standardized the measurements across all STS using 3D‐analysis software. The occlusal, mesial–distal, and buccal–lingual planes were defined to partition, each STS and produce a mesh. The thickness values of each 3D slice were documented in a coordinate system chart to generate a scatter graph. Graphs were embedded into images (Orange software) and images were analyzed via hierarchical clustering. Three STS groups were identified according to shape. Two shapes corresponded to the maxilla defects: a square ( n = 13) with dimensions of 10 mm in a lingual–buccal (length) and 7–10 mm in a mesial–distal (width) direction a rectangle ( n = 11) of 11 mm in length and 4–7 mm in width. The average shape for mandible defects ( n = 9) was smaller (6–8 mm in length, 5–10 mm in width). The highest thickness in all STS was in the buccal portion, above the alveolar ridge, with median values of 2 mm. The lowest thickness of 0.2 mm was at the edges. The study developed novel methodology to design customized, as well as average shape STS for volume augmentation. Future STS harboring adapted geometry might increase volume augmentation efficiency and accuracy, while reducing surgical time.
Publisher: Wiley
Date: 07-12-2022
DOI: 10.1111/JERD.12990
Abstract: This study aims to validate the standardized procedure for designing soft tissue substitutes (STS) adapted to optimally fit single‐tooth defects in the anterior jaws and double‐tooth defects in the posterior jaw and to compare mathematically modeled average shapes. Casts from 35 patients with 17 single‐tooth defects in anterior region and 21 double‐tooth defects in posterior region were scanned. STS were designed and sectioned in 3D slices meshes. Thickness values were documented respecting mesial‐distal and buccal‐lingual orientations. Graphs were embedded into images, and hierarchical clustering was applied to group STS according to shape and thickness. STS clustered into two groups per defect type. For anterior single defects, STS ( n = 4) were either a small and thin oval: 7 mm buccal‐lingual, 4–5 mm mesial‐distal direction and 1.1–1.5 mm thick or a larger oval ( n = 13): 9 mm buccal‐lingual, 5–7 mm mesial‐distal and 1.6 m thick. For posterior double tooth defects, STS ( n = 10) were either narrow, long and thick: 6–7 mm buccal‐lingual, 16–20 mm mesial‐distal and 2.2 thick or a wide, thinner rectangle ( n = 11): 9–11 mm buccal‐lingual, 12–14 mm mesial‐distal and 1.1–1.5 mm thick. The study validated the standardized digital method to design grafts for soft tissue volume augmentation and identified four average shapes for anterior single‐tooth and posterior double‐tooth soft tissue defects. We developed and validated a standardized digital method to design an optimal geometrical shape of a soft tissue substitute for oral volume augmentation and combined it with mathematical modeling to identify average shapes for single‐interior, and double‐posterior tooth defects. The identified average shapes offer the possibility to produce better‐fitted xenografts or synthetic STS blocks requiring minimal chair‐side adaptation leading to reduced clinical time and patient discomfort and potentially improving soft tissue volume augmentation outcomes.
Publisher: MDPI AG
Date: 15-07-2020
DOI: 10.3390/JCM9072238
Abstract: Three-dimensional (3D) printing technology allows the production of an in idualized 3D object based on a material of choice, a specific computer-aided design and precise manufacturing. Developments in digital technology, smart biomaterials and advanced cell culturing, combined with 3D printing, provide promising grounds for patient-tailored treatments. In dentistry, the “digital workflow” comprising intraoral scanning for data acquisition, object design and 3D printing, is already in use for manufacturing of surgical guides, dental models and reconstructions. 3D printing, however, remains un-investigated for oral mucosa/gingiva. This scoping literature review provides an overview of the 3D printing technology and its applications in regenerative medicine to then describe 3D printing in dentistry for the production of surgical guides, educational models and the biological reconstructions of periodontal tissues from laboratory to a clinical case. The biomaterials suitable for oral soft tissues printing are outlined. The current treatments and their limitations for oral soft tissue regeneration are presented, including “off the shelf” products and the blood concentrate (PRF). Finally, tissue engineered gingival equivalents are described as the basis for future 3D-printed oral soft tissue constructs. The existing knowledge exploring different approaches could be applied to produce patient-tailored 3D-printed oral soft tissue graft with an appropriate inner architecture and outer shape, leading to a functional as well as aesthetically satisfying outcome.
Location: Switzerland
No related grants have been discovered for Irena Sailer.