ORCID Profile
0000-0002-1824-5087
Current Organisation
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
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Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0TB01967D
Abstract: The efficiency of photodynamic therapy (PDT) is severely constrained due to the innate hypoxic environment, besides the elevated level of glutathione (GSH).
Publisher: Elsevier BV
Date: 06-2019
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C7DT04093H
Abstract: The disulfide bond (–S–S–) is an enormously valuable functional group in a variety of chemical and biological agents that display effective reactivity or biological activities ( e.g. , antitumor activities).
Publisher: American Chemical Society (ACS)
Date: 12-03-2020
Publisher: Elsevier BV
Date: 02-2019
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9NR06450H
Abstract: This review summarizes the recent progress in UCNP-based nanotherapeutics by highlighting the increasingly developing trend of TME-responsive UCNMs.
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0NR04634E
Abstract: An X-ray-triggered NO-released Bi–SNO nanoparticle was developed for combined treatment of photothermal-therapy, radiotherapy, and gas therapy.
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C7DT04141A
Abstract: NIR light-induced imaging-guided cancer therapy is an encouraging route in the cancer theranostic field.
Publisher: Elsevier BV
Date: 07-2016
DOI: 10.1038/MI.2015.105
Abstract: Human and mouse respiratory tracts show anatomical and physiological differences, which will benefit from alternative experimental models for studying many respiratory diseases. Pig has been recognized as a valuable biomedical model, in particular for lung transplantation or pathologies such as cystic fibrosis and influenza infection. However, there is a lack of knowledge about the porcine respiratory immune system. Here we segregated and studied six populations of pig lung dendritic cells (DCs)/macrophages (Mθs) as follows: conventional DCs (cDC) 1 and cDC2, inflammatory monocyte-derived DCs (moDCs), monocyte-derived Mθs, and interstitial and alveolar Mθs. The three DC subsets present migratory and naive T-cell stimulation capacities. As observed in human and mice, porcine cDC1 and cDC2 were able to induce T-helper (Th)1 and Th2 responses, respectively. Interestingly, porcine moDCs increased in the lung upon influenza infection, as observed in the mouse model. Pig cDC2 shared some characteristics observed in human but not in mice, such as the expression of FCɛRIα and Langerin, and an intra-epithelial localization. This work, by unraveling the extended similarities of the porcine and human lung DC/Mθ networks, highlights the relevance of pig, both as an exploratory model of DC/Mθ functions and as a model for human inflammatory lung pathologies.
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7TB01983A
Abstract: Low tissue penetration depth of the excited light and complicated synthetic procedures greatly hinder the clinical application of photodynamic therapy (PDT).
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7NR01836C
Abstract: Lanthanide-doped photon upconverting nanomaterials are evolving as a new class of imaging contrast agents, offering highly promising prospects in the area of biomedical applications.
Location: Spain
No related grants have been discovered for Angel Ezquerra.