ORCID Profile
0000-0001-7489-8624
Current Organisations
Monash Health
,
Alfred Health
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Publisher: Wiley
Date: 26-07-2022
DOI: 10.1111/ANS.17097
Publisher: Wiley
Date: 28-08-2021
DOI: 10.1111/CODI.15868
Abstract: Perforations are a rare but serious complication of colorectal cancer. The current standard of treatment is emergent surgery followed by adjuvant chemotherapy. The concern with this approach is not only the uncertainty of achieving a R0 resection but also potential injury to adjacent vessels, nerves and ureters due to inflamed tissue planes. A subset of this patient population with a contained perforation who are clinically stable may have superior oncological outcomes with local sepsis control, neoadjuvant therapy followed by radical resection. The aim of this study is to report on the pre‐operative safety profile for neoadjuvant therapy in the setting of an abscess from colon cancer perforation and the short‐term oncological surgical quality outcomes. In this retrospective observational study, all consecutive perforated colon cancer receiving neoadjuvant therapy from Jan 2010 to Dec 2019 were included. There were 21 patients that met the inclusion criteria. The most common symptom at presentation was abdominal pain (71.4%) and most common site of perforation was sigmoid colon (61.9%). Local sepsis control was achieved with a combination of radiological or surgical drainage, erting ostomy and/or intravenous antibiotics. Thirteen patients had long‐course chemoradiation and eight patients had neoadjuvant chemotherapy. Of these, 13 (61.9%) had tumour regression, with one patient having a pathological complete response. All patients achieved a R0 resection. In a small subset of patients with colon cancer perforation, this study has demonstrated the potential safe usage of neoadjuvant therapy first before radical surgery to achieve a clear resection margin.
Publisher: Wiley
Date: 20-11-2023
DOI: 10.1111/CODI.16394
Publisher: AME Publishing Company
Date: 06-2019
Publisher: Oxford University Press (OUP)
Date: 10-2019
DOI: 10.1093/JSCR/RJZ278
Abstract: Bowel perforation is a rare and unusual complication of laparoscopic adjustable gastric band (LAGB) insertion, which if left undiagnosed can have potentially fatal consequences. We present the first case ever published of a delayed presentation of small-bowel perforation secondary to a laparoscopic port insertion. A young woman presented to Emergency Department with intermittent vague abdominal pain for 5 months, on the background of having a LAGB inserted 4 years prior. She was subsequently found to have a small-bowel perforation with mesenteric adhesions to a laparoscopic port site. The patient underwent a successful small-bowel resection with primary anastomosis and made an uneventful recovery.
Publisher: AME Publishing Company
Date: 12-2020
DOI: 10.21037/DMR-20-74
Publisher: Springer Science and Business Media LLC
Date: 04-05-2021
Publisher: Oxford University Press (OUP)
Date: 03-2020
DOI: 10.1093/JSCR/RJAA008
Abstract: An internal hernia is a protrusion of viscera through a congenital or acquired defect in the mesentery of peritoneum. They account for & .9% of all small bowel obstructions [1] and ~4% of obstructions due to hernias [2]. We present a rare case of closed loop obstruction secondary to a band adhesion traversing the lower abdomen from a sigmoid colon appendage epiploicae to the right pelvic wall. A 82-year-old woman presented to the emergency department with nausea, vomiting and worsening right sided abdominal pain for 24 h, on the background of previous pelvic radiation and hysterectomy for uterine cancer. She was subsequently found to have a closed loop obstruction with 30 cm of ischemic bowel strangulated by a band adhesion from a sigmoid colon appendage epiploicae to the right abdominal wall. The patient underwent a successful small bowel resection with primary anastomosis and made an uneventful recovery.
Publisher: Wiley
Date: 21-09-2023
DOI: 10.1111/CODI.16335
No related grants have been discovered for Rathin Gosavi.