ORCID Profile
0000-0002-3381-214X
Current Organisation
University of Sydney
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In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Information Systems | Information Systems Development Methodologies | Artificial Intelligence and Image Processing | Pattern Recognition and Data Mining | Image Processing | Information Storage, Retrieval And Management | Simulation And Modelling | Library and Information Studies | Medical and Health Sciences not elsewhere classified | Information Systems Development Methodologies | Simulation and Modelling | Global Information Systems | Health Information Systems (Incl. Surveillance) | Interfaces And Presentation (Excl. Computer-Human Interaction) | Data Storage Representations | Information Systems Organisation | Communications Technologies | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) | Decision Support And Group Support Systems | Multimedia Programming | Medical Devices | Biomaterials | Biomedical Engineering | Antenna Technology | Digital Systems | Computer Communications Networks | Analysis Of Algorithms And Complexity | Multimedia | Astronomy And Astrophysics | Bioinformatics | Pattern Recognition
Information processing services | Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified | Diagnostic methods | Diagnostic Methods | Application tools and system utilities | Organs, diseases and abnormal conditions not elsewhere classified | Information and Communication Services not elsewhere classified | Health and Support Services not elsewhere classified | Cancer and related disorders | Solar-photoelectric | Skeletal System and Disorders (incl. Arthritis) | Physical sciences | Information services not elsewhere classified | Health and support services not elsewhere classified | Technological and organisational innovation | Integrated circuits and devices | Expanding Knowledge in the Medical and Health Sciences | Medical Instruments | Health Education and Promotion | Public health not elsewhere classified | Expanding Knowledge in the Biological Sciences | Other |
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2017
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: Springer Nature Switzerland
Date: 2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 12-2020
Publisher: Springer Science and Business Media LLC
Date: 06-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 05-2020
Publisher: IEEE
Date: 04-2019
Publisher: Elsevier
Date: 2020
Publisher: Elsevier
Date: 2020
Publisher: No publisher found
Date: 2019
Publisher: Elsevier BV
Date: 03-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2019
Publisher: Elsevier BV
Date: 04-2019
Publisher: Springer International Publishing
Date: 2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2019
Publisher: Springer Science and Business Media LLC
Date: 15-09-2018
Publisher: IEEE
Date: 04-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 11-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 12-2021
Publisher: Elsevier BV
Date: 03-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2022
Publisher: Elsevier
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 12-2021
Publisher: No publisher found
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2021
Publisher: Springer London
Date: 2009
Publisher: Springer Nature Switzerland
Date: 2023
Publisher: Springer International Publishing
Date: 2020
Publisher: Elsevier BV
Date: 06-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2023
Publisher: IEEE
Date: 04-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 12-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: Springer Nature Switzerland
Date: 2023
Publisher: No publisher found
Date: 2020
Publisher: ACM
Date: 15-10-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2022
Publisher: Springer Nature Switzerland
Date: 2023
Publisher: Springer Science and Business Media LLC
Date: 03-06-2023
DOI: 10.1007/S11633-022-1406-4
Abstract: Over the last decade, supervised deep learning on manually annotated big data has been progressing significantly on computer vision tasks. But, the application of deep learning in medical image analysis is limited by the scarcity of high-quality annotated medical imaging data. An emerging solution is self-supervised learning (SSL), among which contrastive SSL is the most successful approach to rivalling or outperforming supervised learning. This review investigates several state-of-the-art contrastive SSL algorithms originally on natural images as well as their adaptations for medical images, and concludes by discussing recent advances, current limitations, and future directions in applying contrastive SSL in the medical domain.
Publisher: Elsevier BV
Date: 11-2020
Publisher: Cold Spring Harbor Laboratory
Date: 20-07-2022
DOI: 10.1101/2022.07.19.500604
Abstract: The spatial architecture of the tumour microenvironment and phenotypic heterogeneity of tumour cells have been shown to be associated with cancer prognosis and clinical outcomes, including survival. Recent advances in highly multiplexed imaging, including imaging mass cytometry (IMC), capture spatially resolved, high-dimensional maps that quantify dozens of disease-relevant biomarkers at single-cell resolution, that contain potential to inform patient-specific prognosis. However, existing automated methods for predicting survival typically do not leverage spatial phenotype information captured at the single-cell level, and current methods tend to focus on a single modality, such as patient variables (PVs). There is no end-to-end method designed to leverage the rich information in whole IMC images and all marker channels, and aggregate this information with PVs in a complementary manner to predict survival with enhanced accuracy. We introduce a deep multimodal graph-based network (DMGN) that integrates entire IMC images and multiple PVs for end-to-end survival prediction of breast cancer. We propose a multimodal graph-based module that considers relationships between spatial phenotype information in all image regions and all PVs, and scales each region–PV pair based on its relevance to survival. We propose another module to automatically generate embeddings specialised for each PV to enhance multimodal aggregation. We show that our modules are consistently effective at improving survival prediction performance using two public datasets, and that DMGN can be applied to an independent validation dataset across the same antigens but different antibody clones. Our DMGN outperformed state-of-the-art methods at survival prediction.
Publisher: ACM
Date: 15-10-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2023
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2022
Publisher: Springer Science and Business Media LLC
Date: 19-01-2019
DOI: 10.1007/S11548-019-01916-2
Abstract: Our aim was to develop an interactive 3D direct volume rendering (DVR) visualization solution to interpret and analyze complex, serial multi-modality imaging datasets from positron emission tomography-computed tomography (PET-CT). Our approach uses: (i) a serial transfer function (TF) optimization to automatically depict particular regions of interest (ROIs) over serial datasets with consistent anatomical structures (ii) integration of a serial segmentation algorithm to interactively identify and track ROIs on PET and (iii) parallel graphics processing unit (GPU) implementation for interactive visualization. Our DVR visualization more easily identifies changes in ROIs in serial scans in an automated fashion and parallel GPU computation which enables interactive visualization. Our approach provides a rapid 3D visualization of relevant ROIs over multiple scans, and we suggest that it can be used as an adjunct to conventional 2D viewing software from scanner vendors.
Publisher: Springer Nature Switzerland
Date: 2023
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 05-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2023
Publisher: Elsevier BV
Date: 03-2019
DOI: 10.1016/J.CMPB.2018.12.031
Abstract: Prostate segmentation on Magnetic Resonance (MR) imaging is problematic because disease changes the shape and boundaries of the gland and it can be difficult to separate the prostate from surrounding tissues. We propose an automated model that extracts and combines multi-level features in a deep neural network to segment prostate on MR images. Our proposed model, the Propagation Deep Neural Network (P-DNN), incorporates the optimal combination of multi-level feature extraction as a single model. High level features from the convolved data using DNN are extracted for prostate localization and shape recognition, while labeling propagation, by low level cues, is embedded into a deep layer to delineate the prostate boundary. A well-recognized benchmarking dataset (50 training data and 30 testing data from patients) was used to evaluate the P-DNN. When compared it to existing DNN methods, the P-DNN statistically outperformed the baseline DNN models with an average improvement in the DSC of 3.19%. When compared to the state-of-the-art non-DNN prostate segmentation methods, P-DNN was competitive by achieving 89.9 ± 2.8% DSC and 6.84 ± 2.5 mm HD on training sets and 84.13 ± 5.18% DSC and 9.74 ± 4.21 mm HD on testing sets. Our results show that P-DNN maximizes multi-level feature extraction for prostate segmentation of MR images.
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2021
Publisher: Elsevier
Date: 2020
Publisher: Wiley
Date: 23-12-2020
DOI: 10.1002/AJS4.96
Publisher: IEEE
Date: 07-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2020
Publisher: Elsevier BV
Date: 06-2020
Publisher: Elsevier BV
Date: 2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2022
Publisher: Springer International Publishing
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 06-2023
Publisher: Springer International Publishing
Date: 2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 09-2018
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2022
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2023
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 08-2023
Publisher: Elsevier BV
Date: 08-2019
DOI: 10.1016/J.MEDIA.2019.06.005
Abstract: The availability of large-scale annotated image datasets and recent advances in supervised deep learning methods enable the end-to-end derivation of representative image features that can impact a variety of image analysis problems. Such supervised approaches, however, are difficult to implement in the medical domain where large volumes of labelled data are difficult to obtain due to the complexity of manual annotation and inter- and intra-observer variability in label assignment. We propose a new convolutional sparse kernel network (CSKN), which is a hierarchical unsupervised feature learning framework that addresses the challenge of learning representative visual features in medical image analysis domains where there is a lack of annotated training data. Our framework has three contributions: (i) we extend kernel learning to identify and represent invariant features across image sub-patches in an unsupervised manner. (ii) We initialise our kernel learning with a layer-wise pre-training scheme that leverages the sparsity inherent in medical images to extract initial discriminative features. (iii) We adapt a multi-scale spatial pyramid pooling (SPP) framework to capture subtle geometric differences between learned visual features. We evaluated our framework in medical image retrieval and classification on three public datasets. Our results show that our CSKN had better accuracy when compared to other conventional unsupervised methods and comparable accuracy to methods that used state-of-the-art supervised convolutional neural networks (CNNs). Our findings indicate that our unsupervised CSKN provides an opportunity to leverage unannotated big data in medical imaging repositories.
Publisher: Elsevier
Date: 2020
Publisher: CRC Press
Date: 31-10-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2019
Publisher: IEEE
Date: 04-2019
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2019
Publisher: Elsevier BV
Date: 02-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2020
Publisher: IEEE
Date: 06-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 05-2021
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2021
Publisher: Springer Science and Business Media LLC
Date: 21-05-2019
DOI: 10.1007/S11548-019-01999-X
Abstract: Multidisciplinary team meetings (MDTs) are the standard of care for safe, effective patient management in modern hospital-based clinical practice. Medical imaging data are often the central discussion points in many MDTs, and these data are typically visualised, by all participants, on a common large display. We propose a Web-based MDT visualisation system (WMDT-VS) to allow in idual participants to view the data on their own personal computing devices with the potential to customise the imaging data, i.e. different view of the data to that of the common display, for their particular clinical perspective. We developed the WMDT-VS by leveraging the state-of-the-art Web technologies to support four MDT visualisation features: (1) 2D and 3D visualisations for multiple imaging modality data (2) a variety of personal computing devices, e.g. smartphone, tablets, laptops and PCs, to access and navigate medical images in idually and share the visualisations (3) customised participant visualisations and (4) the addition of extra local image data for visualisation and discussion. We outlined these MDT visualisation features on two simulated MDT settings using different imaging data and usage scenarios. We measured compatibility and performances of various personal, consumer-level, computing devices. Our WMDT-VS provides a more comprehensive visualisation experience for MDT participants.
Publisher: No publisher found
Date: 2020
Publisher: Elsevier BV
Date: 02-2020
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 03-2021
Location: United States of America
Start Date: 2017
End Date: 2021
Funder: Australian Research Council
View Funded ActivityStart Date: 2004
End Date: 2009
Funder: Australian Research Council
View Funded ActivityStart Date: 2003
End Date: 2003
Funder: Australian Research Council
View Funded ActivityStart Date: 2003
End Date: 2003
Funder: Australian Research Council
View Funded ActivityStart Date: 02-2004
End Date: 11-2004
Amount: $10,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 05-2006
End Date: 05-2011
Amount: $634,946.00
Funder: Australian Research Council
View Funded ActivityStart Date: 06-2020
End Date: 12-2023
Amount: $480,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 05-2006
End Date: 06-2009
Amount: $425,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2016
End Date: 12-2019
Amount: $390,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 08-2005
End Date: 11-2009
Amount: $480,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 08-2003
End Date: 07-2006
Amount: $172,536.00
Funder: Australian Research Council
View Funded ActivityStart Date: 01-2015
End Date: 12-2018
Amount: $355,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 03-2018
End Date: 06-2022
Amount: $4,420,408.00
Funder: Australian Research Council
View Funded ActivityStart Date: 12-2011
End Date: 12-2015
Amount: $386,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 11-2010
End Date: 12-2014
Amount: $430,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 12-2016
End Date: 12-2019
Amount: $360,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2010
End Date: 12-2014
Amount: $610,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 06-2014
End Date: 06-2018
Amount: $342,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 03-2004
End Date: 11-2004
Amount: $10,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 12-2007
End Date: 12-2010
Amount: $390,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 05-2004
End Date: 12-2009
Amount: $700,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 05-2017
End Date: 12-2021
Amount: $481,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 03-2005
End Date: 02-2009
Amount: $456,632.00
Funder: Australian Research Council
View Funded ActivityStart Date: 09-2004
End Date: 12-2011
Amount: $1,600,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 05-2004
End Date: 12-2004
Amount: $10,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 09-2009
End Date: 12-2012
Amount: $470,000.00
Funder: Australian Research Council
View Funded Activity