ORCID Profile
0000-0002-3132-2913
Current Organisations
King's College London
,
University of Oxford
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Publisher: Frontiers Media SA
Date: 03-06-2020
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0CC01904F
Abstract: A new set of H 2 O 2 -responsive PVA hydrogels were formed using the boronate fluorescent probe PF1 and the novel boronate fluorescent probe PT1 as the covalent crosslinkers.
Publisher: Future Science Ltd
Date: 11-2020
Abstract: As bacteria continue to develop resistance to our existing treatment options, antibiotic innovation remains overlooked. If current trends continue, then we could face the stark reality of a postantibiotic era, whereby routine bacterial infections could once again become deadly. In light of a warning signaled by the WHO, a number of new initiatives have been established in the hope of reinvigorating the antibiotic drug development pipeline. In this perspective, we aim to summarize some of these initiatives and funding options, as well as providing an insight into the predicament that we face. Using clinical trials data, company website information and the most recent press releases, a current update of the antibiotic drug development pipeline is also included.
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0BM01918F
Abstract: The optical response of an alkaline phosphatase (ALP) probe was evaluated against various bacterial species.
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8CC04316G
Abstract: A novel fluorescence-based scaffold was developed enabling the production of ‘AND’ based fluorescence probes – ROS/RNS and a second analyte.
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9CC07759F
Abstract: Here, a reaction-based indicator displacement hydrogel assay (RIA) was developed for the detection of hydrogen peroxide (H 2 O 2 ) via the oxidative release of the optical reporter Alizarin Red S (ARS).
Publisher: Frontiers Media SA
Date: 30-04-2019
Publisher: Springer Science and Business Media LLC
Date: 17-01-2018
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8CS00185E
Abstract: We review recent advances in the design and application of excited-state intramolecular proton-transfer (ESIPT) based fluorescent probes. These sensors and imaging agents (probes) are important in biology, physiology, pharmacology, and environmental science.
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9RA04908H
Abstract: With this research we set out to develop of a number of coumarin-based ‘AND’ logic fluorescence probes that were capable of detecting a chosen analyte in the presence of HCys.
Publisher: American Chemical Society (ACS)
Date: 12-06-2020
Abstract: Herein, we demonstrate a combined fluorescent probe/shape-encoded hydrogel strategy for the fast, sensitive, and selective detection of bacterial species via their characteristic enzymes. A poly(vinyl alcohol) (PVA) hydrogel loaded with the fluorescent probe
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Adam C. Sedgwick.