ORCID Profile
0000-0002-5710-1115
Current Organisations
Noakhali Science and Technology University
,
University of Dhaka
,
Tottori University
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Publisher: Informa UK Limited
Date: 2018
Publisher: Bentham Science Publishers Ltd.
Date: 26-10-2016
Publisher: Medknow
Date: 11-2014
Publisher: Springer Science and Business Media LLC
Date: 07-05-2014
DOI: 10.1038/JA.2014.56
Abstract: The objective of this study was to determine the presence of ciprofloxacin and pharmacokinetics of ciprofloxacin in blood plasma of broiler chicken after single oral administration at feeding state. Ciprofloxacin was administered orally at 10 mg kg(-1) to each of the 10 broiler chickens at feeding state. Presence of ciprofloxacin was determined by TLC method and pharmacokinetics by HPLC method. Peak plasma concentration (Cmax) of ciprofloxacin, 0.26±0.03 mg l(-1) was achieved at 4.40±0.1 h (Tmax). Biological half-life of ciprofloxacin was 5.25±0.02 h. Area under the curve (AUC) was 13.397±0.13 mg ml(-1) h, elimination rate constant was 0.13±0.02 h(-1), volume of distribution was 0.194±0.04 l kg(-1) and bioavailability was 49±0.48%. On the basis of the results of the present study, we conclude that, feeding state may have a vital effect on the pharmacokinetic profile of ciprofloxacin in broiler blood plasma.
Publisher: Marmara Pharmaceutical Journal
Date: 20-06-2017
Publisher: Elsevier BV
Date: 05-2019
Publisher: Marmara Pharmaceutical Journal
Date: 12-01-2018
DOI: 10.12991/MPJ.2018.47
Publisher: Springer Science and Business Media LLC
Date: 28-10-2014
No related grants have been discovered for Mohammad Salim Hossain.