ORCID Profile
0000-0002-0432-9298
Current Organisations
Australian Institute of Management in Western Australia
,
capstone health occupational & travel
,
Rockingham General Hospital
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Publisher: Unpublished
Date: 2017
Publisher: Elsevier BV
Date: 03-2022
Publisher: Unpublished
Date: 2019
Publisher: Public Library of Science (PLoS)
Date: 24-08-2023
DOI: 10.1371/JOURNAL.PGPH.0001687
Abstract: Though many studies on COVID have been published to date, data on COVID-19 epidemiology, symptoms, risk factors and severity in low- and middle-income countries (LMICS), such as Afghanistan are sparse. To describe clinical characteristics, severity, and outcomes of patients hospitalized in the MSF COVID-19 treatment center (CTC) in Herat, Afghanistan and to assess risk factors associated with severe outcomes. 1113 patients were included in this observational study between June 2020 and April 2022. Descriptive analysis was performed on clinical characteristics, complications, and outcomes of patients. Univariate description by Cox regression to identify risk factors for an adverse outcome was performed. Adverse outcome was defined as death or transfer to a level 3 intensive care located at another health facility. Finally, factors identified were included in a multivariate Cox survival analysis. A total of 165 patients (14.8%) suffered from a severe disease course, with a median time of 6 days (interquartile range: 2–11 days) from admission to adverse outcome. In our multivariate model, we identified male gender, age over 50, high O2 flow administered during admission, lymphopenia, anemia and O2 saturation = 93% during the first three days of admission as predictors for a severe disease course (p .05). Our analysis concluded in a relatively low rate of adverse outcomes of 14.8%. This is possibly related to the fact that the resources at an MSF-led facility are higher, in terms of human resources as well as supply of drugs and biomedical equipment, including oxygen therapy devices, compared to local hospitals. Predictors for severe disease outcomes were found to be comparable to other settings.
Location: Australia
Location: No location found
Location: Peru
Location: Australia
No related grants have been discovered for Saschveen Singh.